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  1. 1.   CDK2 Inhibition Produces a Persistent Population of Polyploid Cancer Cells
  2. Tyutyunyk-Massey, Liliya; Chen,Zibo; Liu,Xiuxia; Kawakami, Masanori; Harned,Adam; Ng, Yeap; Harned,Adam; Okpechi,Samuel; Ogunlade,Blessing; Alfaro Mora,Yair; Weigert, Roberto; Narayan,Kedar; Liu,Xi; Dmitrovsky,Ethan
  3. JCI Insight. 2025, Apr 15;
  1. 2.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 3.   Slower CDK4 and faster CDK2 activation in the cell cycle
  2. Zhang,Wengang; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Structure (London, England : 1993). 2024, Apr 23;
  1. 4.   Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B
  2. Muys, Bruna R; Shrestha, Roshan L; Anastasakis, Dimitrios G; Pongor, Lorinc; Li, Xiao Ling; Grammatikakis, Ioannis; Polash, Ahsan; Chari,Raj; Gorospe, Myriam; Harris, Curtis C; Aladjem, Mirit I; Basrai, Munira A; Hafner, Markus; Lal, Ashish
  3. Cell Reports. 2023, Mar 15; 42(3): 112260.
  1. 5.   Context-Dependent Function of Long Noncoding RNA PURPL in Transcriptome Regulation during p53 Activation
  2. Hartford, Corrine Corrina R; Shrestha, Roshan L; Pongor, Lorinc; Zhao,Yongmei; Chen, Xiongfong; Fromont,Caroline; Chaudhary, Ritu; Li, Xiao Ling; Pasterczyk, Katherine R; Kumar, Ravi; Muys, Bruna R; Tsitsipatis, Dimitrios; Chari,Raj; Gorospe, Myriam; Aladjem, Mirit I; Khan, Javed; Basrai, Munira A; Grammatikakis, Ioannis; Lal, Ashish
  3. Molecular and Cellular Biology. 2022, Nov 07; 42(12): e0028922.
  1. 6.   Restoration of microRNA metabolism trigger robust antitumor responses
  2. Bofill De Ros,Xavier
  3. Molecular Therapy. Nucleic Acids. 2022, Sep 13; 29: 498-500.
  1. 7.   Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors
  2. Spano, Virginia; Barreca, Marilia; Rocca, Roberta; Bortolozzi, Roberta; Bai, Ruoli; Carbone, Anna; Raimondi, Maria Valeria; Piccionello, Antonio Palumbo; Montalbano, Alessandra; Alcaro, Stefano; Hamel, Ernest; Viola, Giampietro; Barraja, Paola
  3. European Journal of Medicinal Chemistry. 2021, Feb 15; 212
  1. 8.   RAB19 Directs Cortical Remodeling and Membrane Growth for Primary Ciliogenesis
  2. Jewett, Cayla E.; Soh, Adam W. J.; Lin, Carrie H.; Lu,Quanlong; Lencer, Ezra; Westlake,Christopher; Pearson, Chad G.; Prekeris, Rytis
  3. Developmental Cell. 2021, Feb 8; 56(3): 325-340.e8.
  1. 9.   Overproduction of a dominant mutant of the conserved Era GTPase inhibits cell division in Escherichia coli
  2. Zhou, Xiaomei; Peters, Howard K; Li,Xintian; Costantino,Nina; Kumari,Vandana; Shi,Genbin; Tu, Chao; Cameron, Todd A; Haeusser, Daniel P; Vega, Daniel E; Ji, Xinhua; Margolin, William; Court,Don
  3. Journal of bacteriology. 2020, NOV; 202(21): pii: JB.00342-20.
  1. 10.   Impact of losing hRpn13 Pru or UCHL5 on proteasome clearance of ubiquitinated proteins and RA190 cytotoxicity
  2. Osei Amponsa,Vasty; Sridharan, Vinidhra; Tandon,Mayank; Evans,Christine; Klarmann,Kim; Cheng,Oscar; Lack,Justin; Chari,Raj; Walters,Kylie
  3. Molecular and cellular biology. 2020, SEP; 40(18):
  1. 11.   Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA damage response in Purkinje neuron progenitors
  2. Casoni, Filippo; Croci, Laura; Bosone, Camilla; D'Ambrosio, Roberta; Badaloni, Aurora; Gaudesi, Davide; Barili, Valeria; Sarna, Justyna R; Tessarollo, Lino; Cremona, Ottavio; Hawkes, Richard; Warming, Søren; Consalez, G Giacomo
  3. Development. 2017, Oct 15; 144(20): 3686-3697.
  1. 12.   NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction
  2. Juhasz, Agnes; Markel, Susan; Gaur, Shikha; Liu, Han; Lu, Jiamo; Jiang, Guojian; Wu, Xiwei; Antony, Smitha; Wu, Yongzhong; Melillo, Giovanni; Meitzler, Jennifer L; Haines, Diana; Butcher, Donna; Roy, Krishnendu; Doroshow, James H
  3. Journal of Biological Chemistry. 2017, May 12; 292(19): 7866-7887.
  1. 13.   The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression
  2. Randles, L.; Anchoori, R. K.; Roden, R. B.; Walters, K. J.
  3. The Journal of biological chemistry. 2016, 15-Apr; 291(16): 8773-83.
  1. 14.   MDM1 is a microtubule-binding protein that negatively regulates centriole duplication
  2. Van de Mark, D.; Kong, D.; Loncarek, J.; Stearns, T.
  3. Molecular Biology of the Cell. 2015, 1-Nov; 26(21): 3788-802.
  1. 15.   Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration
  2. Diril, M. K.; Ratnacaram, C. K.; Padmakumar, V. C.; Du, T. H.; Wasser, M.; Coppola, V.; Tessarollo, L.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2012, Mar; 109(10): 3826-3831.
  1. 16.   MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells
  2. Viola, G.; Bortolozzi, R.; Hamel, E.; Moro, S.; Brun, P.; Castagliuolo, I.; Ferlin, M. G.; Basso, G.
  3. Biochemical Pharmacology. 2012, Jan; 83(1): 16-26.
  1. 17.   Effect of nitric oxide on neointimal hyperplasia based on sex and hormone status
  2. Hogg, M. E.; Varu, V. N.; Vavra, A. K.; Popowich, D. A.; Banerjee, M. N.; Martinez, J.; Jiang, Q.; Saavedra, J. E.; Keefer, L. K.; Kibbe, M. R.
  3. Free Radical Biology and Medicine. 2011, May; 50(9): 1065-1074.
  1. 18.   C/EBP ? targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression
  2. Pawar, S. A.; Sarkar, T. R.; Balamurugan, K.; Sharan, S.; Wang, J.; Zhang, Y. H.; Dowdy, S. F.; Huang, A. M.; Sterneck, E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2010, May 18; 107(20): 9210-9215.
  1. 19.   Profiling of cell cycle genes of breast cells exposed to etodolac
  2. Roy, D.; Arason, G. A.; Chowdhury, B.; Mitra, A.; Calaf, G. M.
  3. Oncology Reports. 2010, May; 23(5): 1383-1391.
  1. 20.   Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations
  2. Chang, S.; Biswas, K.; Martin, B. K.; Stauffer, S.; Sharan, S. K.
  3. Journal of Clinical Investigation. 2009, Oct; 119(10): 3160-71.
  1. 21.   Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G(1)/S transition
  2. Li, W.; Kotoshiba, S.; Berthet, C.; Hilton, M. B.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(2): 486-491.
  1. 22.   Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
  2. Satyanarayana, A.; Kaldis, P.
  3. Oncogene. 2009 28(33): 2925-2939.
  1. 23.   Towards inferring time dimensionality in protein-protein interaction networks by integrating structures: the p53 example
  2. Tuncbag, N.; Kar, G.; Gursoy, A.; Keskin, O.; Nussinov, R.
  3. Molecular Biosystems. 2009 5(12): 1770-1778.
  1. 24.   In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide
  2. Kil, W. J.; Cerna, D.; Burgan, W. E.; Beam, K.; Carter, D.; Steeg, P. S.; Tofilon, P. J.; Camphausen, K.
  3. Clinical Cancer Research. 2008 14(3): 931-938.
  1. 25.   Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2
  2. Satyanarayana, A.; Berthet, C.; Lopez-Molina, J.; Coppola, V.; Tessarollo, L.; Kaldis, P.
  3. Development. 2008 135(20): 3389-3400.
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