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  1. 1.   Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNaV 1.7 and hCaV 3 voltage-gated channels
  2. Giribaldi, Julien; Chemin, Jean; Tuifua, Marie; Deuis, Jennifer R; Mary, Rosanna; Vetter, Irina; Wilson, David T; Daly, Norelle L; Schroeder, Christina I; Bourinet, Emmanuel; Dutertre, Sébastien
  3. The FEBS Journal. 2023, Mar 13;
  1. 2.   µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype NaV1.7
  2. McMahon, Kirsten L; Tran, Hue N T; Deuis, Jennifer R; Craik, David J; Vetter, Irina; Schroeder, Christina I
  3. Toxins. 2022, Aug 30; 14(9):
  1. 3.   HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCe Activation
  2. Mancardi, Daniele; Pagliaro, Pasquale; Ridnour,Lisa; Tocchetti, Carlo G; Miranda, Katrina; Juhaszova, Magdalena; Sollott, Steven J; Wink,David; Paolocci, Nazareno
  3. Antioxidants (Basel, Switzerland). 2022, Feb 14; 11(2):
  1. 4.   Structural and functional insights into inhibition of human voltage-gated sodium channels by µ-conotoxin KIIIA disulfide isomers
  2. Tran, Hue N T; McMahon, Kirsten L; Deuis, Jennifer R; Vetter, Irina; Schroeder,Christina
  3. The Journal of Biological Chemistry. 2022, Feb 12; 298(3): 101728.
  1. 5.   Small cyclic sodium channel inhibitors
  2. Peigneur, Steve; da Costa Oliveira, Cristina; de Sousa Fonseca, Flávia Cristina; McMahon, Kirsten L; Mueller, Alexander; Cheneval, Olivier; Cristina Nogueira Freitas, Ana; Starobova, Hana; Dimitri Gama Duarte, Igor; Craik, David J; Vetter, Irina; de Lima, Maria Elena; Schroeder,Christina; Tytgat, Jan
  3. Biochemical Pharmacology. 2021, Jan; 183: 114291.
  1. 6.   Pharmacological activity and NMR solution structure of the leech peptide HSTX-I
  2. McMahon, Kirsten L; Tay, Bryan; Deuis, Jennifer R; Tanaka, Brian S; Peigneur, Steve; Jin, Ai-Hua; Tytgat, Jan; Waxman, Stephen G; Dib-Hajj, Sulayman D; Vetter, Irina; Schroeder,Christina
  3. Biochemical pharmacology. 2020, NOV; 181(SI): 114082.
  1. 7.   Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible NaV Channel Inhibitor
  2. McMahon, Kirsten L; Tran, Hue N T; Deuis, Jennifer R; Lewis, Richard J; Vetter, Irina; Schroeder,Christina
  3. Biomedicines. 2020, Oct 02; 8(10): E391.
  1. 8.   Bridgehead Modifications of Englerin A Reduce TRPC4 Activity and Intravenous Toxicity but not Cell Growth Inhibition
  2. Wu, Zhenhua; Suppo, Jean-Simon; Tumova, Sarka; Strope, Jonathan; Bravo, Fernando; Moy, Melody; Weinstein, Ethan S; Peer, Cody J; Figg, William D; Chain, William J; Echavarren, Antonio M; Beech, David J; Beutler,John
  3. ACS medicinal chemistry letters. 2020, Sep 10; 11(9): 1711-1716.
  1. 9.   Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization
  2. Hauseman, Zachary J; Harvey, Edward P; Newman, Catherine E; Wales, Thomas E; Bucci, Joel C; Mintseris, Julian; Schweppe, Devin K; David, Liron; Fan,Lixin; Cohen, Daniel T; Herce, Henry D; Mourtada, Rida; Ben-Nun, Yael; Bloch, Noah B; Hansen, Scott B; Wu, Hao; Gygi, Steven P; Engen, John R; Walensky, Loren D
  3. Molecular cell. 2020, JUL 2; 79(1): 68-+.
  1. 10.   Calcium-induced calcium release and type 3 ryanodine receptors modulate the slow afterhyperpolarising current, sI(AHP), and its potentiation in hippocampal pyramidal neurons
  2. Tedoldi, Angelo; Ludwig, Petra; Fulgenzi,Gianluca; Takeshima, Hiroshi; Pedarzani, Paola; Stocker, Martin
  3. PLOS ONE. 2020, JUN 19; 15(7):
  1. 11.   Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction
  2. Younger, Scott; Jang,Hyunbum; Davies, Hannah A; Niemiec, Martin J; Garcia, Joe G N; Nussinov,Ruth; Migrino, Raymond Q; Madine, Jillian; Arce, Fernando T
  3. Biophysical journal. 2020, JUN 2; 118(11): 2769-2782.
  1. 12.   Restriction enzymes use a 24 dimensional coding space to recognize 6 base long DNA sequences
  2. Schneider,Tom; Jejjala, Vishnu
  3. PloS one. 2019, OCT 31; 14(10): e0222419.
  1. 13.   Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs
  2. Matthies, Doreen; Bae, Chanhyung; Toombes, Gilman Es; Fox, Tara; Bartesaghi, Alberto; Subramaniam, Sriram; Swartz, Kenton Jon
  3. eLife. 2018, Aug 15; 7: pii: e37558.
  1. 14.   Antimicrobial Properties of Amyloid Peptides
  2. Kagan, B. L.; Jang, H.; Capone, R.; Arce, F. T.; Ramachandran, S.; Lal, R.; Nussinov, R.
  3. Molecular Pharmaceutics. 2012, Apr; 9(4): 708-717.
  1. 15.   Effects of Point Substitutions on the Structure of Toxic Alzheimer's beta-Amyloid Channels: Atomic Force Microscopy and Molecular Dynamics Simulations
  2. Connelly, L.; Jang, H.; Arce, F. T.; Ramachandran, S.; Kagan, B. L.; Nussinov, R.; Lal, R.
  3. Biochemistry. 2012, Apr; 51(14): 3031-3038.
  1. 16.   Allosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra-molecular communication pathways
  2. Nussinov, R.
  3. British Journal of Pharmacology. 2012, Apr; 165(7): 2110-2112.
  1. 17.   All-D-Enantiomer of beta-Amyloid Peptide Forms Ion Channels in Lipid Bilayers
  2. Capone, R.; Jang, H.; Kotler, S. A.; Connelly, L.; Arce, F. T.; Ramachandran, S.; Kagan, B. L.; Nussinov, R.; Lal, R.
  3. Journal of Chemical Theory and Computation. 2012, Mar; 8(3): 1143-1152.
  1. 18.   Probing Structural Features of Alzheimer's Amyloid-beta Pores in Bilayers Using Site-Specific Amino Acid Substitutions
  2. Capone, R.; Jang, H.; Kotler, S. A.; Kagan, B. L.; Nussinov, R.; Lal, R.
  3. Biochemistry. 2012, Jan; 51(3): 776-785.
  1. 19.   Dystrophin Is Required for the Normal Function of the Cardio-Protective K(ATP) Channel in Cardiomyocytes
  2. Graciotti, L.; Becker, J.; Granata, A. L.; Procopio, A. D.; Tessarollo, L.; Fulgenzi, G.
  3. Plos One. 2011, Oct; 6(10): 10.
  1. 20.   Polymorphism of amyloid beta peptide in different environments: implications for membrane insertion and pore formation
  2. Arce, F. T.; Jang, H. B.; Ramachandran, S.; Landon, P. B.; Nussinov, R.; Lal, R.
  3. Soft Matter. 2011, Jun 7; 7(11): 5267-5273.
  1. 21.   Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link
  2. Jang, H. J. H.; Arce, F. T.; Mustata, M.; Ramachandran, S.; Capone, R.; Nussinov, R.; Lal, R.
  3. Biophysical Journal. 2011, Apr; 100(7): 1775-1783.
  1. 22.   Conserved Intramolecular Disulfide Bond Is Critical to Trafficking and Fate of ATP-binding Cassette (ABC) Transporters ABCB6 and Sulfonylurea Receptor 1 (SUR1)/ABCC8
  2. Fukuda, Y.; Aguilar-Bryan, L.; Vaxillaire, M.; Dechaume, A.; Wang, Y.; Dean, M.; Moitra, K.; Bryan, J.; Schuetz, J. D.
  3. Journal of Biological Chemistry. 2011, Mar; 286(10): 8481-8492.
  1. 23.   Molecular-Level Examination of Cu2+ Binding Structure for Amyloid Fibrils of 40-Residue Alzheimer's beta by Solid-State NMR Spectroscopy
  2. Parthasarathy, S.; Long, F.; Miller, Y.; Xiao, Y. L.; McElheny, D.; Thurber, K.; Ma, B. Y.; Nussinov, R.; Ishii, Y.
  3. Journal of the American Chemical Society. 2011, Mar; 133(10): 3390-3400.
  1. 24.   Role of vascular K(ATP) channels in blood pressure variability after sinoaortic denervation in rats
  2. Yang, Z. W.; Li, D. J.; Liu, C.; Han, P.; Yang, Y. L.; Su, D. F.; Shen, F. M.
  3. Acta Pharmacologica Sinica. 2011, Feb; 32(2): 194-200.
  1. 25.   beta-Barrel Topology of Alzheimer's beta-Amyloid Ion Channels
  2. Jang, H.; Arce, F. T.; Ramachandran, S.; Capone, R.; Lal, R.; Nussinov, R.
  3. Journal of Molecular Biology. 2010, Dec; 404(5): 917-934.
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