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  1. 1.   Abrogation of the G2/M checkpoint as a chemo sensitization approach for alkylating agents
  2. Lang, Fengchao; Cornwell, James A; Kaur, Karambir; Elmogazy, Omar; Zhang, Wei; Zhang, Meili; Song, Hua; Sun,David; Wu,Xiaolin; Aladjem, Mirit I; Aregger,Michael; Cappell, Steven D; Yang, Chunzhang
  3. Neuro-Oncology. 2023, Dec 22;
  1. 2.   Considerations for a Reliable In Vitro Model of Chemotherapy-Induced Peripheral Neuropathy
  2. Eldridge, Sandy; Scuteri, Arianna; Jones, Eugenia M. C.; Cavaletti, Guido; Guo, Liang; Glaze, Elizabeth
  3. Toxics. 2021, Nov 11; 9(11):
  1. 3.   Adcitmer(R), a new CD56-targeting monomethyl auristatin E-conjugated antibody, is a potential therapeutic approach in Merkel cell carcinoma
  2. Esnault, C.; Martin, C.; Desgranges, A.; Baltus, C. B.; Aubrey, N.; Lakhrif, Z.; Lajoie, L.; Lantier, L.; Clemenceau, B.; Sarma, B.; Schrama, J.; Houben, R.; Schrama, D.; Hesbacher, S.; Feng,Yang; Dimitrov, D.; Guyetant, S.; Berthon, P.; Viaud-Massuard, M. C.; Samimi, M.; Touze, A.; Kervarrec, T.
  3. The British Journal of Dermatology. 2021, Sep 28;
  1. 4.   A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations
  2. Zhang, Zhiying; Hu, Kaiwen; Miyake, Kentaro; Kiyuna, Tasuku; Oshiro, Hiromichi; Wangsiricharoen, Sintawat; Kawaguchi, Kei; Higuchi, Takashi; Razmjooei, Sahar; Miyake, Masuyo; Chawla, Sant P; Singh,Shree Ram; Hoffman, Robert M
  3. Scientific reports. 2020, Nov 18; 10(1): 20105.
  1. 5.   Treatment of HIV-associated Primary CNS Lymphoma with Antiretroviral Therapy, Rituximab, and High-Dose Methotrexate
  2. Lurain, Kathryn; Uldrick, Thomas S; Ramaswami, Ramya; Polizzotto, Mark; Goncalves, Priscila; Widell, Anaida; Steinberg, Seth M; Jaffe, Elaine S; Pittaluga, Stefania; Wang, Hao-Wei; Yuan, Constance; Tamula,Mary Anne; Martin, Staci; Wolters, Pamela L; George, Jomy; Little, Richard F; Yarchoan, Robert
  3. Blood. 2020, NOV 5; 136(19): 2229-2232.
  1. 6.   CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells
  2. Grant, Corena V; Cai, Shengxin; Risinger, April L; Liang, Huiyun; O'Keefe,Barry; Doench, John G; Cichewicz, Robert H; Mooberry, Susan L
  3. Journal of natural products. 2020, OCT 23; 83(10): 3080-3092.
  1. 7.   Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model
  2. Philippou, Yiannis; Sjoberg, Hanna T.; Murphy, Emma; Alyacoubi, Said; Jones, Keaton I.; Gordon-Weeks, Alex N.; Phyu, Su; Parkes, Eileen E.; Gillies McKenna, W.; Lamb, Alastair D.; Gileadi, Uzi; Cerundolo, Vincenzo; Scheiblin,David; Lockett,Stephen; Wink,David; Mills, Ian G.; Hamdy, Freddie C.; Muschel, Ruth J.; Bryant, Richard J.
  3. BRITISH JOURNAL OF CANCER. 2020, JUL 9;
  1. 8.   Protection of hematopoietic stem cells from stress-induced exhaustion and aging
  2. Singh,Shweta; Jakubison,Brad; Keller,Jonathan
  3. Current opinion in hematology. 2020, JUL; 27(4): 225-231.
  1. 9.   Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets
  2. Krushkal, Julia; Silvers,Thomas; Reinhold, William C; Sonkin, Dmitriy; Vural, Suleyman; Connelly, John; Varma, Sudhir; Meltzer, Paul S; Kunkel, Mark; Rapisarda,Annamaria; Evans, David; Pommier, Yves; Teicher, Beverly A
  3. Clinical epigenetics. 2020, Jun 25; 12(1): 93.
  1. 10.   Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment
  2. Maniati, Eleni; Berlato, Chiara; Gopinathan, Ganga; Heath, Owen; Kotantaki, Panoraia; Lakhani, Anissa; McDermott, Jacqueline; Pegrum, Colin; Delaine-Smith, Robin M; Pearce, Oliver M T; Hirani, Priyanka; Joy, Joash D; Szabova,Ludmila; Perets, Ruth; Sansom, Owen J; Drapkin, Ronny; Bailey, Peter; Balkwill, Frances R
  3. Cell reports. 2020, Jan 14; 30(2): 525-540.e7.
  1. 11.   Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice
  2. Wang,Guohao; Xu, Junji; Zhao, Jiangsha; Yin, Weiqin; Liu, Dayong; Chen, WanJun; Hou, Steven X
  3. Nature communications. 2020, Jan 10; 11(1): 220.
  1. 12.   A Comparative Review of Chemotherapy-Induced Peripheral Neuropathy in In Vivo and In Vitro Models
  2. Eldridge, Sandy; Guo,Liang; Hamre, John
  3. Toxicologic pathology. 2019, Jul 22;
  1. 13.   A Pilot Study of Liposomal Doxorubicin Combined with Bevacizumab followed by Bevacizumab Monotherapy in Patients with Advanced Kaposi Sarcoma
  2. Ramaswami, Ramya; Uldrick, Thomas S; Polizzotto, Mark N; Wyvill, Kathleen M; Goncalves, Priscila; Widell, Anaida; Lurain, Kathryn; Steinberg, Seth M; Figg, William D; Tosato, Giovanna; Whitby,Denise; Yarchoan, Robert
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019, JUL 15; 25(14): 4238-4247.
  1. 14.   Identification of a mechanogenetic link between substrate stiffness and chemotherapeutic response in breast cancer
  2. Medina, Scott H; Bush, Brian; Cam, Maggie; Sevcik, Emily; DelRio, Frank W; Nandy, Kaustav; Schneider, Joel
  3. Biomaterials. 2019, May; 202: 1-11.
  1. 15.   A patient-derived orthotopic xenograft (PDOX) nude-mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma
  2. Zhang, Zhiying; Hu, Kaiwen; Kiyuna, Tasuko; Miyake, Kentaro; Kawaguchi, Kei; Igarashi, Kentaro; Nelson, Scott D; Li, Yunfeng; Singh, Shree Ram; Hoffman, Robert M
  3. Pharmacological research. 2019, Apr; 142: 169-175.
  1. 16.   Design, synthesis and preclinical evaluation of 5-methyl-N4-aryl-furo[2,3-d]pyrimidines as single agents with combination chemotherapy potential
  2. Devambatla, Ravi Kumar Vyas; Choudhary, Shruti; Ihnat, Michael; Hamel, Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & Medicinal Chemistry Letters. 2018, Oct 1; 28(18): 3085-3093.
  1. 17.   LMTK3 confers chemo-resistance in breast cancer
  2. Stebbing, Justin; Shah, Kalpit; Lit, Lei Cheng; Gagliano, Teresa; Ditsiou, Angeliki; Wang, Tingting; Wendler, Franz; Simon, Thomas; Szabo, Krisztina Sara; O'Hanlon, Tim; Dean, Michael; Roslani, April Camilla; Cheah, Swee Hung; Lee, Soo-Chin; Giamas, Georgios
  3. ONCOGENE. 2018, JUN; 37(23): 3113-3130.
  1. 18.   Anticancer activity of Schiff base-Poloxamer P85 combination against kidney cancer
  2. Dogan, Aysegul; Demirci, Selami; Telci, Dilek; Canikyan, Serli; Kongur, Merve; Dede, Bülent; Sahin, Fikrettin
  3. International urology and nephrology. 2018, Feb; 50(2): 247-255.
  1. 19.   PML: Regulation and multifaceted function beyond tumor suppression
  2. Hsu, Kuo-Sheng; Kao, Hung-Ying
  3. Cell and Bioscience. 2018, Jan 25; 8: 5.
  1. 20.   Preoperative transcatheter arterial chemotherapy may suppress oxidative stress in hepatocellular carcinoma cells and reduce the risk of short-term relapse
  2. Su, Hao; Zhu, Guangzhi; Djaja P, Ketut Indra; Lin, Yi; Gong, Yizhen; Liu, Xiaoguang; Li, Jiaquan; Liu, Zhiming; Qin, Xiao; Li, Lequn; Liu, Tangwei; Lu, Zili; Wei, Minyi; Yan, Lunan; Winkler, Cheryl; O'Brien, Stephen J; Li, Jing; Xiao, Kaiyin; Peng, Tao
  3. Oncotarget. 2017, Aug 15; 8(33): 54402-54415.
  1. 21.   Schiff base-Poloxamer P85 combination demonstrates chemotherapeutic effect on prostate cancer cells in vitro.
  2. Demirci, Selami; Dogan, Aysegül; Türkmen, Nese Basak; Telci, Dilek; Rizvanov, Albert A; Sahin, Fikrettin
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017, Feb; 86: 492-501.
  1. 22.   Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo [3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple -acting angiokinase inhibition as antitumor agents
  2. Pavana, Roheeth Kumar; Choudhary, Shruti; Bastian, Anja; Ihnat, Michael A.; Bai, Ruoli; Hamel, Ernest; Gangjee, Aleem
  3. BIOORGANIC & MEDICINAL CHEMISTRY. 2017, Jan 15; 25(2): 545-556.
  1. 23.   A Phase I Study of Veliparib in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and Lymphomas
  2. Kummar, S.; Ji, J. P.; Morgan, R.; Lenz, H. J.; Puhalla, S. L.; Belani, C. P.; Gandara, D. R.; Allen, D.; Kiesel, B.; Beumer, J. H.; Newman, E. M.; Rubinstein, L.; Chen, A.; Zhang, Y. P.; Wang, L. H.; Kinders, R. J.; Parchment, R. E.; Tomaszewski, J. E.; Doroshow, J. H.
  3. Clinical Cancer Research. 2012, Mar; 18(6): 1726-1734.
  1. 24.   Preclinical therapeutic response of residual metastatic disease is distinct from its primary tumor of origin
  2. Day, C. P.; Carter, J.; Bonomi, C.; Hollingshead, M.; Merlino, G.
  3. International Journal of Cancer. 2012, Jan; 130(1): 190-199.
  1. 25.   Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells
  2. Bulut, G.; Hong, S. H.; Chen, K.; Beauchamp, E. M.; Rahim, S.; Kosturko, G. W.; Glasgow, E.; Dakshanamurthy, S.; Lee, H. S.; Daar, I.; Toretsky, J. A.; Khanna, C.; Uren, A.
  3. Oncogene. 2012, Jan; 31(3): 269-281.
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