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  1. 1.   The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress
  2. Stromberg, Benjamin R.; Singh, Mayank; Torres, Adrian E.; Burrows, Amy C.; Pal, Debjani; Insinna, Christine; Rhee, Yosup; Dickson, Andrew S.; Westlake,Christopher; Summers, Matthew K.
  3. The Journal of Biological Chemistry. 2021, Oct; 297(4):
  1. 2.   Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy
  2. Lountos, G. T.; Jobson, A. G.; Tropea, J. E.; Self, C. R.; Zhang, G. T.; Pommier, Y.; Shoemaker, R. H.; Waugh, D. S.
  3. Journal of Structural Biology. 2011, Dec; 176(3): 292-301.
  1. 3.   In vitro and In vivo Radiosensitization with AZD6244 (ARRY-142886), an Inhibitor of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase 1/2 Kinase
  2. Chung, E. J.; Brown, A. P.; Asano, H.; Mandler, M.; Burgan, W. E.; Carter, D.; Camphausen, K.; Citrin, D.
  3. Clinical Cancer Research. 2009 15(9): 3050-3057.
  1. 4.   Cellular Inhibition of Checkpoint Kinase 2 (Chk2) and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor PV1019 [7-Nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]
  2. Jobson, A. G.; Lountos, G. T.; Lorenzi, P. L.; Llamas, J.; Connelly, J.; Cerna, D.; Tropea, J. E.; Onda, A.; Zoppoli, G.; Kondapaka, S.; Zhang, G. T.; Caplen, N. J.; Cardellina, J. H.; Yoo, S. S.; Monks, A.; Self, C.; Waugh, D. S.; Shoemaker, R. H.
  3. Journal of Pharmacology and Experimental Therapeutics. 2009 331(3): 816-826.
  1. 5.   Identification of a bis-guanylhydrazone 4,4 '-diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555 as a novel chemotype for inhibition of Chk2 kinase
  2. Jobson, A. G.; Cardellina, J. H.; Scudiero, D.; Kondapaka, S.; Zhang, H.; Kim, H.; Shoemaker, R.; Pommier, Y.
  3. Molecular Pharmacology. 2007, Oct; 72(4): 876-884.
  1. 6.   7-hydroxystaurosporine (UCN-01) inhibition of Akt Thr(308) but not Ser(473) phosphorylation: A basis for decreased insulin-stimulated glucose transport
  2. Kondapaka, S. B.; Zarnowski, M. J.; Yver, D. R.; Sausville, E. A.; Cushman, S. W.
  3. Clinical Cancer Research. 2004, NOV 1; 10(21): 7192-7198.
  1. 7.   Mos positively regulates Xe-Wee1 to lengthen the first mitotic cell cycle of Xenopus
  2. Murakami, M. S.; Copeland, T. D.; Vande Woude, G. F.
  3. Genes & Development. 1999 13(5): 620-631.
  1. 8.   Irreversible G(2)-M Arrest and Cytoskeletal Reorganization Induced By Cytotoxic Nucleoside Analogues
  2. Halloran, P. J.; Fenton, R. G.
  3. Cancer Research. 1998 58(17): 3855-3865.
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