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  1. 1.   Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors
  2. Takebe, Naoko; Naqash, Abdul Rafeh; Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Do, Khanh; Bruns, Ashley; Juwara,Lamin; Zlott, Jennifer; Rubinstein, Larry; Piekarz, Richard; Sharon, Elad; Streicher, Howard; Mittra, Arjun; Miller, Sarah B.; Ji,Jay; Wilsker,Deborah; Kinders,Robert; Parchment,Ralph; Chen,Li; Chang,Ting-Chia; Das,Biswajit; Mugundu, Ganesh; Doroshow, James H.; Chen, Alice P.
  3. CLINICAL CANCER RESEARCH. 2021, Apr 16; 27(14): 3834-3844.
  1. 2.   CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute
  2. Zoppoli, G.; Solier, S.; Reinhold, W. C.; Liu, H.; Connelly, J. W.; Monks, A.; Shoemaker, R. H.; Abaan, O. D.; Davis, S. R.; Meltzer, P. S.; Doroshow, J. H.; Pommier, Y.
  3. Oncogene. 2012, Jan; 31(4): 403-418.
  1. 3.   Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155
  2. Chang, S. H.; Wang, R. H.; Akagi, K.; Kim, K. A.; Martin, B. K.; Cavallone, L.; Haines, D. C.; Basik, M.; Mai, P.; Poggi, E.; Isaacs, C.; Looi, L. M.; Mun, K. S.; Greene, M. H.; Byers, S. W.; Teo, S. H.; Deng, C. X.; Sharan, S. K.; Kathleen Cuningham Fdn, C.
  3. Nature Medicine. 2011, Oct; 17(10): 1275-U308.
  1. 4.   Epimorphic regeneration in mice is p53-independent
  2. Arthur, L. M.; Demarest, R. M.; Clark, L.; Gourevitch, D.; Bedelbaeva, K.; Anderson, R.; Snyder, A.; Capobianco, A. J.; Lieberman, P.; Feigenbaum, L.; Heber-Katz, E.
  3. Cell Cycle. 2010, Sep; 9(18): 3667-3673.
  1. 5.   Histone yH2AX and Poly(ADP-Ribose) as Clinical Pharmacodynamic Biomarkers
  2. Redon, C. E.; Nakamura, A. J.; Zhang, Y. W.; Ji, J. P.; Bonner, W. M.; Kinders, R. J.; Parchment, R. E.; Doroshow, J. H.; Pommier, Y.
  3. Clinical Cancer Research. 2010, Sep; 16(18): 4532-4542.
  1. 6.   Interleukin-15 Enhances Proteasomal Degradation of Bid in Normal Lymphocytes: Implications for Large Granular Lymphocyte Leukemias
  2. Hodge, D. L.; Yang, J.; Buschman, M. D.; Schaughency, P. M.; Dang, H.; Bere, W.; Yang, Y. L.; Savan, R.; Subleski, J. J.; Yin, X. M.; Loughran, T. P.; Young, H. A.
  3. Cancer Research. 2009 69(9): 3986-3994.
  1. 7.   Targeting the ubiquitin-proteasome system for cancer therapy
  2. Yang, Y. L.; Kitagaki, J.; Wang, H.; Hou, D. X.; Perantoni, A. O.
  3. Cancer Science. 2009 100(1): 24-28.
  1. 8.   Aberrant splicing induced by missense mutations in BRCA1: clues from a humanized mouse model
  2. Yang, Y. P.; Swaminathan, S.; Martin, B. K.; Sharan, S. K.
  3. Human Molecular Genetics. 2003 12(17): 2121-2131.
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