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  1. 1.   The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins
  2. Rosenberg, Eric M; Jian, Xiaoying; Soubias,Olivier; Yoon, Hye-Young; Yadav, Mukesh P; Hammoudeh, Sarah; Pallikkuth, Sandeep; Akpan, Itoro; Chen, Pei-Wen; Maity, Tapan K; Jenkins, Lisa M; Yohe,Marielle; Byrd,Robert; Randazzo, Paul A
  3. The Journal of Biological Chemistry. 2023, Feb 07; 299(3): 102992.
  1. 2.   SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations
  2. Liao, Tsung-Jen; Jang,Hyunbum; Fushman, David; Nussinov,Ruth
  3. The Journal of chemical physics. 2020, Jul 28; 153(4): 045106.
  1. 3.   High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1
  2. Liao,Tsung-Jen; Jang,Hyunbum; Nussinov,Ruth; Fushman, David
  3. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2020, Feb 19; 142: 3401-3411.
  1. 4.   Leucine zipper transcription factor-like 1 binds adaptor protein complex-1 and 2 and participates in trafficking of transferrin receptor 1
  2. Promchan,Kanyarat; Natarajan,Ven
  3. PloS one. 2020, JAN 2; 15(1): e0226298.
  1. 5.   Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity.
  2. Czikora, Agnes; Lundberg, Daniel J; Abramovitz, Adelle; Lewin, Nancy E; Kedei, Noemi; Peach, Megan L; Zhou, Xiaoling; Merritt, Raymond C; Craft, Elizabeth A; Braun, Derek C; Blumberg, Peter M
  3. The Journal of biological chemistry. 2016, May 20; 291(21): 11133-47.
  1. 6.   The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling
  2. Lim, J.; Zhou, M.; Veenstra, T. D.; Morrison, D. K.
  3. Genes & Development. 2010, Jul; 24(14): 1496-1506.
  1. 7.   In vitro and in vivo analysis of neurotrophin-3 activation of Arf6 and Rac-1
  2. Esteban, P. F.; Caprari, P.; Yoon, H. Y.; Randazzo, P. A.; Tessarollo, L.
  3. Small Gtpases in Disease, Part A. 2008 438: 171-183.
  1. 8.   Integrating signals from RTKs to ERK/MAPK
  2. McKay, M. M.; Morrison, D. K.
  3. Oncogene. 2007, May; 26(22): 3113-3121.
  1. 9.   The scaffold protein Cybr is required for cytokine-modulated trafficking of leukocytes in vivo
  2. Coppola, V.; Barrick, C. A.; Bobisse, S.; Rodriguez-Galan, M. C.; Pivetta, M.; Reynolds, D.; Howard, O. M. Z.; Palko, M. E.; Esteban, P. F.; Young, H. A.; Rosato, A.; Tessarollo, L.
  3. Molecular and Cellular Biology. 2006, Jul; 26(14): 5249-5258.
  1. 10.   Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
  2. Lee, S.; Tsai, Y. C.; Mattera, R.; Smith, W. J.; Kostelansky, M. S.; Weissman, A. M.; Bonifacino, J. S.; Hurley, J. H.
  3. Nature Structural & Molecular Biology. 2006, MAR; 13(3): 264-271.
  1. 11.   Cytokinesis regulator ECT2 changes its conformation through phosphorylation at Thr-341 in G2/M phase
  2. Hara, T.; Abe, M.; Inoue, H.; Yu, L. R.; Veenstra, T. D.; Kang, Y. H.; Lee, K. S.; Miki, T.
  3. Oncogene. 2006, JAN; 25(4): 566-578.
  1. 12.   Rap-GEF signaling controls stem cell anchoring to their niche through regulating DE-cadherin-mediated cell adhesion in the Drosophila testis
  2. Wang, H.; Singh, S. R.; Zheng, Z. Y.; Oh, S. W.; Chen, X.; Edwards, K.; Hou, S. X.
  3. Developmental Cell. 2006, JAN; 10(1): 117-126.
  1. 13.   Ras-GRF1 signaling is required for normal beta-cell development and glucose homeostasis
  2. de Mora, J. F.; Esteban, L. M.; Burks, D. J.; Nunez, A.; Garces, C.; Garcia-Barrado, M. J.; Iglesias-Osma, M. C.; Moratinos, J.; Ward, J. M.; Santos, E.
  3. Embo Journal. 2003 22(12): 3039-3049.
  1. 14.   Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development
  2. Fernandez-Medarde, A.; Esteban, L. M.; Nunez, A.; Porteros, A.; Tessarollo, L.; Santos, E.
  3. Molecular and Cellular Biology. 2002 22(8): 2498-2504.
  1. 15.   The Sos1-Rac1 signaling - Possible involvement of a vacuolar H+ -ATPase E subunit
  2. Miura, K.; Miyazawa, S.; Furuta, S.; Mitsushita, J.; Kamijo, K.; Ishida, H.; Miki, T.; Suzukawa, K.; Resau, J.; Copeland, T. D.; Kamata, T.
  3. Journal of Biological Chemistry. 2001 276(49): 46276-46283.
  1. 16.   Macrophage stimulating protein
  2. Leonard, E. J.; Danilkovitch, A.
  3. Advances in Cancer Research, Vol 77. 2000 77: 139-167.
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