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  1. 1.   Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors
  2. Krushkal, Julia; Zhao, Yingdong; Roney, Kyle; Zhu, Weimin; Brooks,Alan; Wilsker,Deborah; Parchment, Ralph E; McShane, Lisa M; Doroshow, James H
  3. Epigenetics. 2024, Dec; 19(1): 2309824.
  1. 2.   Synthesis and Biological Evaluation of Novel 2-Aroyl Benzofuran-Based Hydroxamic Acids as Antimicrotubule Agents
  2. Mariotto, Elena; Canton, Martina; Marchioro, Chiara; Brancale, Andrea; Hamel,Ernest; Varani, Katia; Vincenzi, Fabrizio; De Ventura, Tiziano; Padroni, Chiara; Viola, Giampietro; Romagnoli, Romeo
  3. International Journal of Molecular Sciences. 2024, Jul 09; 25(14):
  1. 3.   Romidepsin-induced HIV-1 viremia during effective antiretroviral therapy contains identical viral sequences with few deleterious mutations
  2. Winckelmann, Anni; Barton, Kirston; Hiener, Bonnie; Schlub, Timothy E.; Shao, Wei; Rasmussen, Thomas A.; Ostergaard, Lars; Sogaard, Ole S.; Tolstrup, Martin; Palmer, Sarah
  3. AIDS. 2017, Mar 27; 31(6): 771-779.
  1. 4.   EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR
  2. Wang, C. X.; Liu, Z. H.; Woo, C. W.; Li, Z. J.; Wang, L. F.; Wei, J. S.; Marquez, V. E.; Bates, S. E.; Jin, Q. H.; Khan, J.; Ge, K.; Thiele, C. J.
  3. Cancer Research. 2012, Jan; 72(1): 315-324.
  1. 5.   Methotrexate induces apoptosis through p53/p21-dependent pathway and increases E-cadherin expression through downregulation of HDAC/EZH2
  2. Huang, W. Y.; Yang, P. M.; Chang, Y. F.; Marquez, V. E.; Chen, C. C.
  3. Biochemical Pharmacology. 2011, Feb; 81(4): 510-517.
  1. 6.   Identification of Four Potential Epigenetic Modulators from the NCI Structural Diversity Library Using a Cell-Based Assay
  2. Best, A. M.; Chang, J. J.; Dull, A. B.; Beutler, J. A.; Martinez, E. D.
  3. Journal of Biomedicine and Biotechnology. 2011 11.
  1. 7.   Total Synthesis and Biological Evaluation of Largazole and Derivatives with Promising Selectivity for Cancers Cells
  2. Zeng, X.; Yin, B. L.; Hu, Z.; Liao, C. Z.; Liu, J. L.; Li, S.; Li, Z.; Nicklaus, M. C.; Zhou, G. B.; Jiang, S.
  3. Organic Letters. 2010, Mar; 12(6): 1368-1371.
  1. 8.   Laboratory correlates for a phase II trial of romidepsin in cutaneous and peripheral T-cell lymphoma
  2. Bates, S. E.; Zhan, Z. R.; Steadman, K.; Obrzut, T.; Luchenko, V.; Frye, R.; Robey, R. W.; Turner, M.; Gardner, E. R.; Figg, W. D.; Steinberg, S. M.; Ling, A.; Fojo, T.; To, K. W.; Piekarz, R. L.
  3. British Journal of Haematology. 2010, Jan; 148(2): 256-267.
  1. 9.   Epigenetic gene regulation in stem cells and correlation to cancer
  2. Mathews, L. A.; Crea, F.; Farrar, W. L.
  3. Differentiation. 2009, Jul; 78(1): 1-17.
  1. 10.   Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts
  2. Baschnagel, A.; Russo, A.; Burgan, W. E.; Carter, D.; Beam, K.; Palmieri, D.; Steeg, P. S.; Tofilon, P.; Camphausen, K.
  3. Molecular Cancer Therapeutics. 2009 8(6): 1589-1595.
  1. 11.   Determination of a benzamide histone deacetylase inhibitor, MS-275, in human plasma by liquid chromatography with mass-spectrometric detection
  2. Danish, M.; Gardner, E. R.; Chen, X. H.; Figg, W. D.
  3. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 2009 877(3): 355-359.
  1. 12.   Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast
  2. Fischer, T.; Cui, B. W.; Dhakshnamoorthy, J.; Zhou, M.; Rubin, C.; Zofall, M.; Veenstra, T. D.; Grewal, S.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(22): 8998-9003.
  1. 13.   Bioactive Food Components, Inflammatory Targets, and Cancer Prevention
  2. Kim, Y. S.; Young, M. R.; Bobe, G.; Colburn, N. H.; Milner, J. A.
  3. Cancer Prevention Research. 2009 2(3): 200-208.
  1. 14.   The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo
  2. Lucas, D. M.; Edwards, R. B.; Lozanski, G.; West, D. A.; Shin, J. D.; Vargo, M. A.; Davis, M. E.; Rozewski, D. M.; Johnson, A. J.; Su, B. N.; Goettl, V. M.; Heerema, N. A.; Lin, T. S.; Lehman, A.; Zhang, X. L.; Jarjoura, D.; Newman, D. J.; Byrd, J. C.
  3. Blood. 2009 113(19): 4656-4666.
  1. 15.   Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts
  2. Monks, A.; Hose, C. D.; Pezzoli, P.; Kondapaka, S.; Vansant, G.; Petersen, K. D.; Sehested, M.; Monforte, J.; Shoemaker, R. H.
  3. Anti-Cancer Drugs. 2009 20(8): 682-692.
  1. 16.   Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks
  2. Palmieri, D.; Lockman, P. R.; Thomas, F. C.; Hua, E.; Herring, J.; Hargrave, E.; Johnson, M.; Flores, N.; Qian, Y. Z.; Vega-Valle, E.; Taskar, K. S.; Rudraraju, V.; Mittapalli, R. K.; Gaasch, J. A.; Bohn, K. A.; Thorsheim, H. R.; Liewehr, D. J.
  3. Clinical Cancer Research. 2009 15(19): 6148-6157.
  1. 17.   Population Pharmacokinetics of Romidepsin in Patients with Cutaneous T-Cell Lymphoma and Relapsed Peripheral T-Cell Lymphoma
  2. Woo, S.; Gardner, E. R.; Chen, X. H.; Ockers, S. B.; Baum, C. E.; Sissung, T. M.; Price, D. K.; Frye, R.; Piekarz, R. L.; Bates, S. E.; Figg, W. D.
  3. Clinical Cancer Research. 2009 15(4): 1496-1503.
  1. 18.   Determination of the cyclic depsipeptide FK228 in human and mouse plasma by liquid chromatography with mass-spectrometric detection
  2. Chen, X. H.; Gardner, E. R.; Figg, W. D.
  3. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 2008 865(1-2): 153-158.
  1. 19.   The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation
  2. Song, C. C.; Xiao, Z.; Nagashima, K.; Li, C.; Lockett, S. J.; Dai, R. M.; Cho, E. H.; Conrads, T. P.; Veenstra, T. D.; Colburn, N. H.; Wang, Q.; Wang, J. M.
  3. Toxicology and Applied Pharmacology. 2008 228(3): 351-363.
  1. 20.   Zap70 signaling pathway mediates glucocorticoid receptor-dependent transcriptional activation: role in the regulation of annexin 1 expression in T cells
  2. Ishaq, M.; DeGray, G.; Mou, K.; Aguilera, A.; Yang, J.; Lempicki, R. A.; Hazen, A.; Natarajan, V.
  3. Journal of Immunology. 2007, Sep; 179(6): 3851-3858.
  1. 21.   Pathway analysis identifies perturbation of genetic networks induced by butyrate in a bovine kidney epithelial cell line
  2. Li, C. J.; Li, R. W.; Wang, Y. H.; Elsasser, T. H.
  3. Functional & Integrative Genomics. 2007, Jul; 7(3): 193-205.
  1. 22.   Structure of the POZ domain of human LRF, a master regulator of oncogenesis
  2. Schubot, F. D.; Tropea, J. E.; Waugh, D. S.
  3. Biochemical and Biophysical Research Communications. 2006, Dec; 351(1): 1-6.
  1. 23.   Loss of emerin at the nuclear envelope disrupts the Rb1/E2F and MyoD pathways during muscle regeneration
  2. Melcon, G.; Kozlov, S.; Cutler, D. A.; Sullivan, T.; Hernandez, L.; Zhao, P.; Mitchell, S.; Nader, G.; Bakay, M.; Rottman, J. N.; Hoffman, E. P.; Stewart, C. L.
  3. Human Molecular Genetics. 2006, FEB 15; 15(4): 637-651.
  1. 24.   Gene profiling of PXD-101, a novel hydroxamate type inhibitor of histone deacetylase, leads to identification of aurora kinase inhibition
  2. Hose, C.; Shoemaker, R.; Monks, A.
  3. Clinical Cancer Research. 2005, DEC 15; 11(24, Part 2 Suppl. S): 9152S-9152S.
  1. 25.   Antibody response to a non-conserved C-terminal part of human histone deacetylase 3 in colon cancer patients
  2. Shebzukhov, Y. V.; Koroleva, E. P.; Khlgatian, S. V.; Belousov, P. V.; Kuz'mina, K. E.; Radko, B. V.; Longpre, F.; Lagarkova, M. A.; Kadachigova, T. S.; Gurova, O. V.; Meshcheryakov, A. A.; Lichinitser, M. R.; Knuth, A.; Jager, E.; Kuprash, D. V.; Nedospasov, S. A.
  3. International Journal of Cancer. 2005, DEC 10; 117(5): 800-806.
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