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  1. 1.   77Se-13C based dipolar correlation experiments to map selenium sites in microcrystalline proteins
  2. Quinn, Caitlin M; Xu, Shiping; Hou, Guangjin; Chen, Qingqing; Sail, Deepak; Byrd,Robert; Rozovsky, Sharon
  3. Journal of Biomolecular NMR. 2022, Mar 23;
  1. 2.   Combination Methionine-methylation-axis Blockade: A Novel Approach to Target the Methionine Addiction of Cancer
  2. Higuchi, Takashi; Han, Qinghong; Sugisawa, Norihiko; Yamamoto, Jun; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Bouvet, Michael; Singh, Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M.
  3. Cancer Genomics Proteomics. 2021, Mar-Apr; 18(2): 113-120.
  1. 3.   Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model
  2. Yamamoto, Jun; Miyake, Kentaro; Han, Qinghong; Tan, Yuying; Inubushi, Sachiko; Sugisawa, Norihiko; Higuchi, Takashi; Tashiro, Yoshihiko; Nishino, Hiroto; Homma, Yuki; Matsuyama, Ryusei; Chawla, Sant P; Bouvet, Michael; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Cancer letters. 2020, NOV 1; 492: 174-184.
  1. 4.   Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model
  2. Higuchi, Takashi; Han, Qinghong; Miyake, Kentaro; Oshiro, Hiromichi; Sugisawa, Norihiko; Tan, Yuying; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Biochemical and biophysical research communications. 2020, FEB 26; 523(1): 135-139.
  1. 5.   The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model
  2. Higuchi, Takashi; Sugisawa, Norihiko; Yamamoto, Jun; Oshiro, Hiromichi; Han, Qinghong; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Tan, Yuying; Kuchipudi, Shreya; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer chemotherapy and pharmacology. 2019, Nov 08;
  1. 6.   Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma
  2. Kawaguchi, Kei; Higuchi, Takashi; Li, Shukuan; Han, Qinghong; Tan, Yuying; Igarashi, Kentaro; Zhao, Ming; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Ohshiro, Hiromichi; Sugisawa, Norihiko; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Eckardt, Mark A; Singh, Arun S; Singh, Shree Ram; Eilber, Fritz C; Unno, Michiaki; Hoffman, Robert M
  3. Biochemical and Biophysical Research Communications. 2018, Sep 18; 503(4): 3086-3092.
  1. 7.   Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer
  2. Kawaguchi, Kei; Miyake, Kentaro; Han, Qinghong; Li, Shukuan; Tan, Yuying; Igarashi, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Higuchi, Takashi; Oshiro, Hiromichi; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Bouvet, Michael; Singh, Shree Ram; Unno, Michiaki; Hoffman, Robert M
  3. Cancer Letters. 2018, Jun 18; 432: 251-259.
  1. 8.   Blind prediction of noncanonical RNA structure at atomic accuracy
  2. Watkins, Andrew M.; Geniesse, Caleb; Kladwang, Wipapat; Zakrevsky, Paul; Jaeger, Luc; Das, Rhiju
  3. Science Advances. 2018, May 25; 4(5): eaar5316.
  1. 9.   Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model
  2. Fu, T. M.; Almqvist, J.; Liang, Y. H.; Li, L. F.; Huang, Y. F.; Su, X. D.
  3. Journal of Molecular Biology. 2011, Sep; 412(4): 688-697.
  1. 10.   Serum Cytokine Analysis in a Positive Chemoprevention Trial: Selenium, Interleukin-2, and an Association with Squamous Preneoplastic Disease
  2. Roth, M. J.; Katki, H. A.; Wei, W. Q.; Qiao, Y. L.; Bagni, R.; Wang, G. Q.; Whitby, D.; Dong, Z. W.; Gail, M. H.; Limburg, P. J.; Giffen, C. A.; Taylor, P. R.; Dawsey, S. M.
  3. Cancer Prevention Research. 2010, Jul; 3(7): 810-817.
  1. 11.   NCAD, a Database Integrating the Intrinsic Conformational Preferences of Non-Coded Amino Acids
  2. Revilla-Lopez, G.; Torras, J.; Curco, D.; Casanovas, J.; Calaza, M. I.; Zanuy, D.; Jimenez, A. I.; Cativiela, C.; Nussinov, R.; Grodzinski, P.; Aleman, C.
  3. Journal of Physical Chemistry B. 2010, Jun; 114(21): 7413-7422.
  1. 12.   Structural Basis for Binding of RNA and Cofactor by a KsgA Methyltransferase
  2. Tu, C.; Tropea, J. E.; Austin, B. P.; Court, D. L.; Waugh, D. S.; Ji, X. H.
  3. Structure. 2009 17(3): 374-385.
  1. 13.   A Sulfilimine Bond Identified in Collagen IV
  2. Vanacore, R.; Ham, A.; Voehler, M.; Sanders, C. R.; Conrads, T. P.; Veenstra, T. D.; Sharpless, K. B.; Dawson, P. E.; Hudson, B. G.
  3. Science. 2009 325(5945): 1230-1234.
  1. 14.   MTHFR genotype and colorectal adenoma recurrence: Data from a double-blind placebo-controlled clinical trial
  2. Levine, A. J.; Wallace, K.; Tsang, S.; Haile, R. W.; Saibil, F.; Ahnen, D.; Cole, B. F.; Barry, E. L.; Munroe, D. J.; Ali, I. U.; Uel, P.; Baron, J. A.
  3. Cancer Epidemiology Biomarkers & Prevention. 2008 17(9): 2409-2415.
  1. 15.   Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells
  2. Ohta, S.; Lai, E. W.; Morris, J. C.; Pang, A.; Watanabe, M.; Yazawa, H.; Zhang, R.; Green, J. E.; Chan, W. Y.; Sirajuddin, P.; Taniguchi, S.; Powers, J. F.; Tischler, A. S.; Pacak, K.
  3. Molecular Carcinogenesis. 2008 47(4): 245-251.
  1. 16.   Isolation and characterization of novel cyclotides from Viola hederaceae - Solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide
  2. Chen, B.; Colgrave, M. L.; Daly, N. L.; Rosengren, K. J.; Gustafson, K. R.; Craik, D. J.
  3. Journal of Biological Chemistry. 2005, JUN 10; 280(23): 22395-22405.
  1. 17.   Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway
  2. Chen, S. Y.; Lin, J. R. V.; Darbha, R.; Lin, P. P.; Liu, T. Y.; Chen, Y. M. A.
  3. Cancer Research. 2004 64(10): 3617-3623.
  1. 18.   Differential regulation of responsiveness to fMLP and C5a upon dendritic cell maturation: correlation with receptor expression
  2. Yang, D.; Chen, Q.; Stoll, S.; Chen, X.; Howard, O. M.; Oppenheim, J. J.
  3. Journal of Immunology. 2000 165(5): 2694-702.
  1. 19.   Crystal structure of RNA 3 '-terminal phosphate cyclase, a ubiquitous enzyme with unusual topology
  2. Palm, G. J.; Billy, E.; Filipowicz, W.; Wlodawer, A.
  3. Structure with Folding & Design. 2000 8(1): 13-23.
  1. 20.   N36, a synthetic N-terminal heptad repeat domain of the HIV-1 envelope protein gp41, is an activator of human phagocytes
  2. Le, Y. Y.; Jiang, S.; Hu, J. Y.; Gong, W. H.; Su, S. B.; Dunlop, N. M.; Shen, W. P.; Li, B. Q.; Wang, J. M.
  3. Clinical Immunology. 2000 96(3): 236-242.
  1. 21.   Association of Arsenic-Induced Malignant Transformation With Dna Hypomethylation and Aberrant Gene Expression
  2. Zhao, C. Q.; Young, M. R.; Diwan, B. A.; Coogan, T. P.; Waalkes, M. P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 1997 94(20): 10907-10912.
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