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  1. 1.   Long-term Epigenetic Therapy with Oral Zebularine Has Minimal Side Effects and Prevents Intestinal Tumors in Mice
  2. Yoo, C. B.; Chuang, J. C.; Byun, H. M.; Egger, G.; Yang, A. S.; Dubeau, L.; Long, T.; Laird, P. W.; Marquez, V. E.; Jones, P. A.
  3. Cancer Prevention Research. 2008 1(4): 233-240.
  1. 2.   The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma
  2. Herranz, M.; Martin-Caballero, J.; Fraga, M. F.; Ruiz-Cabello, J.; Flores, J. M.; Desco, M.; Marquez, V.; Esteller, M.
  3. Blood. 2006, FEB 1; 107(3): 1174-1177.
  1. 3.   Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells
  2. Ben-Kasus, T.; Ben-Zvi, Z.; Marquez, V. E.; Kelley, J. A.; Agbaria, R.
  3. Biochemical Pharmacology. 2005, JUL 1; 70(1): 121-133.
  1. 4.   Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine
  2. Dote, H.; Cerna, D.; Burgan, W. E.; Carter, D. J.; Cerra, M. A.; Hollingshead, M. G.; Camphausen, K.; Tofilon, P. J.
  3. Clinical Cancer Research. 2005, JUN 15; 11(12): 4571-4579.
  1. 5.   Zebularine: A unique molecule for an epigenetically based strategy in cancer chemotherapy
  2. Marquez, V. E.; Kelley, J. A.; Agbaria, R.; Ben-Kasus, T.; Cheng, J. C.; Yoo, C. B.; Jones, P. A.
  3. Therapeutic Oligonucleotides: Transcriptional and Translational Strategies for Silencing Gene Expression. 2005; 1058 : 246-254.
  1. 6.   Zebularine: A unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology
  2. Marquez, V. E.; Barchi, J. J.; Kelley, J. A.; Rao, K. V. R.; Agbaria, R.; Ben-Kasus, T.; Cheng, J. C.; Yoo, C. B.; Jones, P. A.
  3. Nucleosides Nucleotides & Nucleic Acids. 2005 24(5-7, Sp. Iss.): 305-318.
  1. 7.   Preferential response of cancer cells to zebularine
  2. Cheng, J. C.; Yoo, C. B.; Weisenberger, D. J.; Chuang, J.; Wozniak, C.; Liang, G. N.; Marquez, V. E.; Greer, S.; Orntoft, T. F.; Thykjaer, T.; Jones, P. A.
  3. Cancer Cell. 2004, AUG; 6(2): 151-158.
  1. 8.   Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line
  2. Pompeia, C.; Hodge, D. R.; Plass, C.; Wu, Y. Z.; Marquez, V. E.; Kelley, J. A.; Farrar, W. L.
  3. Cancer Research. 2004 64(10): 3465-3473.
  1. 9.   Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside (Zebularine) at the G(C)under-barGC recognition domain
  2. Marquez, V. E.; Eritja, R.; Kelley, J. A.; Vanbemmel, D.; Christman, J.
  3. THERAPEUTIC OLIGONUCLEOTIDES. 2003; 1002 : 154-164.
  1. 10.   Inhibition of HhaI DNA (cytosine-C5) methyltransferase by oligodeoxyribonucleotides containing 5-aza-2 '-deoxycytidine: Examination of the intertwined roles of co-factor, target, transition state structure and enzyme conformation
  2. Brank, A. S.; Eritja, R.; Garcia, R. G.; Marquez, V. E.; Christman, J. K.
  3. Journal of Molecular Biology. 2002 323(1): 53-67.
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