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  1. 1.   Synthesis and Evaluation of 1,5-Disubstituted Tetrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative and Antitumor Activity
  2. Romagnoli, R.; Baraldi, P. G.; Salvador, M. K.; Preti, D.; Tabrizi, M. A.; Brancale, A.; Fu, X. H.; Li, J.; Zhang, S. Z.; Hamel, E.; Bortolozzi, R.; Basso, G.; Viola, G.
  3. Journal of Medicinal Chemistry. 2012, Jan; 55(1): 475-488.
  1. 2.   Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2-(3 ',4 ',5 '-Trimethoxybenzoyl)benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis
  2. Romagnoli, R.; Baraldi, P. G.; Lopez-Cara, C.; Cruz-Lopez, O.; Carrion, M. D.; Salvador, M. K.; Bermejo, J.; Estevez, S.; Estevez, F.; Balzarini, J.; Brancale, A.; Ricci, A.; Chen, L. C.; Kim, J. G.; Hamel, E.
  3. Chemmedchem. 2011, Oct; 6(10): 1841-1853.
  1. 3.   Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives
  2. Romagnoli, R.; Baraldi, P. G.; Cruz-Lopez, O.; Tolomeo, M.; Di Cristina, A.; Pipitone, R. M.; Grimaudo, S.; Balzarini, J.; Brancale, A.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry Letters. 2011, May; 21(9): 2746-2751.
  1. 4.   Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents
  2. Romagnoli, R.; Baraldi, P. G.; Cara, C. L.; Hamel, E.; Basso, G.; Bortolozzi, R.; Viola, G.
  3. European Journal of Medicinal Chemistry. 2010, Dec; 45(12): 5781-5791.
  1. 5.   Synthesis and Cellular Pharmacology Studies of a Series of 2-amino-3-aroyl-4-substituted Thiophene Derivatives
  2. Romagnoli, R.; Baraldi, P. G.; Pavani, M. G.; Cruz-Lopez, O.; Hamel, E.; Balzarini, J.; Brognara, E.; Zuccato, C.; Gambari, R.
  3. Medicinal Chemistry. 2010, Nov; 6(6): 329-343.
  1. 6.   Evolution of the total syntheses of ustiloxin natural products and their analogues
  2. Li, P. X.; Evans, C. D.; Wu, Y. Z.; Cao, B.; Hamel, E.; Joullie, M. M.
  3. Journal of the American Chemical Society. 2008 130(7): 2351-2364.
  1. 7.   Synthesis and biological evaluation of 2-amino-3-(3 ',4 ',5 '-trimethoxybenzoyl)-6-substituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridi ne derivatives as antimitotic agents and inhibitors of tubulin polymerization
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cruz-Lopez, O.; Cara, C. L.; Tolomeo, M.; Grimaudo, S.; Di Cristina, A.; Pipitone, M. R.; Balzarini, J.; Kandil, S.; Brancale, A.; Sarkar, T.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry Letters. 2008 18(18): 5041-5045.
  1. 8.   The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase
  2. Marcus, A. I.; Zhou, J.; O'Brate, A.; Hamel, E.; Wong, J.; Nivens, N.; El-Naggar, A.; Yao, T. P.; Khuri, F. R.; Giannakakou, P.
  3. Cancer Research. 2005, MAY 1; 65(9): 3883-3893.
  1. 9.   Sustained intracellular retention of dolastatin 10 causes its potent antimitotic activity
  2. Verdier-Pinard, P.; Kepler, J. A.; Pettit, G. R.; Hamel, E.
  3. Molecular Pharmacology. 2000 57(1): 180-187.
  1. 10.   A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos
  2. Schumacher, J. M.; Ashcroft, N.; Donovan, P. J.; Golden, A.
  3. Development. 1998 125(22): 4391-4402.
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