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  1. 1.   Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned
  2. Stransky, Laura A; Gao, Wenhua; Schmidt,Laura; Bi, Kevin; Ricketts, Christopher J; Ramesh, Vijyendra; James,Amy; Difilippantonio,Simone; Ileva,Lilia; Kalen,Joseph; Karim,Baktiar; Jeon, Albert; Morgan,Tamara; Warner,Andrew; Turan, Sevilay; Unite,Joanne; Tran,Bao; Choudhari,Sulbha; Zhao,Yongmei; Linn, Douglas E; Yun, Changhong; Dhandapani, Sripriya; Parab, Vaishali; Pinheiro, Elaine M; Morris,Nicole; He, Lixia; Vigeant, Sean M; Pignon, Jean-Christophe; Sticco-Ivins, Maura; Signoretti, Sabina; Van Allen, Eliezer M; Linehan, W Marston; Kaelin, William G
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Oct 08; 121(41): e2408549121.
  1. 2.   ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models
  2. Schmid, Sebastian; Russell, Zachary R; Shimura Yamashita,Alex; West, Madeline E; Parrish, Abigail G; Walker, Julia; Rudoy, Dmytro; Yan, James Z; Quist, David C; Gessesse, Betemariyam N; Alvinez, Neriah; Hill, Kimberly D; Anderson,Larry; Cimino, Patrick J; Kumasaka, Debra K; Parchment,Ralph; Holland, Eric C; Szulzewsky, Frank
  3. Cell Reports. 2024, Oct 03; 43(10): 114829.
  1. 3.   Magnetic Resonance Imaging for Monitoring of Hepatic Disease Induced by Ebola Virus: a Nonhuman Primate Proof-of-Concept Study
  2. Lee, Ji Hyun; Calcagno, Claudia; Feuerstein, Irwin M; Solomon,Jeffrey; Mani, Venkatesh; Huzella, Louis; Castro, Marcelo A; Laux, Joseph; Reeder, Rebecca J; Kim, Dong-Yun; Worwa, Gabriella; Thomasson, David; Hagen, Katie R; Ragland, Danny R; Kuhn, Jens H; Johnson, Reed F
  3. Microbiology Spectrum. 2023, May 15; e0353822.
  1. 4.   Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population
  2. Stellas, Dimitris; Karaliota,Sevasti; Stravokefalou, Vasiliki; Angel, Matthew; Nagy,Bethany; Goldfarbmuren,Kate; Bergamaschi, Cristina; Felber,Barbara; Pavlakis,George
  3. Cell Reports. 2023, May 12; 42(5): 112501.
  1. 5.   Longitudinal analyses using 18F-Fluorodeoxyglucose positron emission tomography with computed tomography as a measure of COVID-19 severity in the aged, young, and humanized ACE2 SARS-CoV-2 hamster models
  2. Cong, Yu; Lee, Ji Hyun; Perry, Donna L; Cooper, Kurt; Wang, Hui; Dixit, Saurabh; Liu, David X; Feuerstein, Irwin M; Solomon,Jeffrey; Bartos, Christopher; Seidel, Jurgen; Hammoud, Dima A; Adams, Ricky; Anthony, Scott M; Liang, Janie; Schuko, Nicolette; Li, Rong; Liu, Yanan; Wang, Zhongde; Tarbet, E Bart; Hischak, Amanda M W; Hart, Randy; Isic, Nejra; Burdette, Tracey; Drawbaugh, David; Huzella, Louis M; Byrum, Russell; Ragland, Danny; St Claire, Marisa C; Wada, Jiro; Kurtz, Jonathan R; Hensley, Lisa E; Schmaljohn, Connie S; Holbrook, Michael R; Johnson, Reed F
  3. Antiviral Research. 2023, Apr 15; 105605.
  1. 6.   Creation and preclinical evaluation of a novel mussel-inspired, biomimetic, bioactive bone graft scaffold: direct comparison with Infuse bone graft using a rat model of spinal fusion
  2. Cottrill, Ethan; Pennington, Zach; Wolf,Matthew; Dirckx, Naomi; Ehresman, Jeff; Perdomo-Pantoja, Alexander; Rajkovic, Christian; Lin, Jessica; Maestas, David R; Mageau, Ashlie; Lambrechts, Dennis; Stewart, Veronica; Sciubba, Daniel M; Theodore, Nicholas; Elisseeff, Jennifer H; Witham, Timothy
  3. Journal of Neurosurgery. Spine. 2023, Mar 31; 39(1): 113-121.
  1. 7.   Toward the determination of sensitive and reliable whole-lung computed tomography features for robust standard radiomics and delta-radiomics analysis in a nonhuman primate model of coronavirus disease 2019
  2. Castro, Marcelo A; Reza, Syed; Chu, Winston T; Bradley, Dara; Lee, Ji Hyun; Crozier,Ian; Sayre, Philip J; Lee, Byeong Y; Mani, Venkatesh; Friedrich, Thomas C; O'Connor, David H; Finch, Courtney L; Worwa, Gabriella; Feuerstein, Irwin M; Kuhn, Jens H; Solomon,Jeffrey
  3. Journal of Medical Imaging (Bellingham, Wash.). 2022, Nov; 9(6): 066003.
  1. 8.   Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival
  2. Vijayakurup, Vinod; Maeng, Kyungah; Lee, Hye Seung; Meyer, Benjamin S; Burkett,Sandra; Nawab, Akbar; Dougherty, Michael W; Jobin, Christian; Mahmud, Iqbal; Garrett, Timothy J; Feely, Michael; Lee, Kyoung Bun; Kaye, Frederic J; Guijarro, Maria V; Zajac-Kaye, Maria
  3. JCI Insight. 2022, Sep 01; 7(19):
  1. 9.   Unraveling the Treatment Effect of Baricitinib on Clinical Progression and Resource Utilization in Hospitalized COVID-19 Patients: Secondary Analysis of the Adaptive COVID-19 Treatment Randomized Trial-2
  2. Fintzi, Jonathan; Bonnett,Tyler; Tebas, Pablo; Marconi, Vincent C; Levine, Corri B; El Sahly, Hana M; McLellan, Susan L F; Benson, Constance A; Rostad, Christina A; Ganesan, Anuradha; Huprikar, Nikhil; Frank, Maria G; Mularski, Richard A; Atmar, Robert L; Park, Pauline K; Short, William R; Beigel, John H; Mehta, Aneesh K; Sweeney, Daniel A
  3. Open forum infectious diseases. 2022, Jul; 9(7): ofac219.
  1. 10.   Exploration of Ultralarge Compound Collections for Drug Discovery
  2. Warr, Wendy A; Nicklaus,Marc; Nicolaou, Christos A; Rarey, Matthias
  3. Journal of Chemical Information and Modeling. 2022, Apr 14;
  1. 11.   Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1
  2. Harding, Rachel J.; Deme,Justin; Hevler, Johannes F.; Tamara, Sem; Lemak, Alexander; Cantle, Jeffrey P.; Szewczyk, Magdalena M.; Begeja, Nola; Goss, Siobhan; Zuo, Xiaobing; Loppnau, Peter; Seitova, Alma; Hutchinson, Ashley; Fan,Lixin; Truant, Ray; Schapira, Matthieu; Carroll, Jeffrey B.; Heck, Albert J. R.; Lea, Susan M.; Arrowsmith, Cheryl H.
  3. Communications Biology . 2021, Dec 8; 4(1):
  1. 12.   Considerations for a Reliable In Vitro Model of Chemotherapy-Induced Peripheral Neuropathy
  2. Eldridge, Sandy; Scuteri, Arianna; Jones, Eugenia M. C.; Cavaletti, Guido; Guo, Liang; Glaze, Elizabeth
  3. Toxics. 2021, Nov 11; 9(11):
  1. 13.   Federated learning for predicting clinical outcomes in patients with COVID-19
  2. Dayan, Ittai; Roth, Holger R.; Zhong, Aoxiao; Harouni, Ahmed; Gentili, Amilcare; Abidin, Anas Z.; Liu, Andrew; Costa, Anthony Beardsworth; Wood, Bradford J.; Tsai, Chien-Sung; Wang, Chih-Hung; Hsu, Chun-Nan; Lee, C. K.; Ruan, Peiying; Xu, Daguang; Wu, Dufan; Huang, Eddie; Kitamura, Felipe Campos; Lacey, Griffin; de Antonio Corradi, Gustavo Cesar; Nino, Gustavo; Shin, Hao-Hsin; Obinata, Hirofumi; Ren, Hui; Crane, Jason C.; Tetreault, Jesse; Guan, Jiahui; Garrett, John W.; Kaggie, Joshua D.; Park, Jung Gil; Dreyer, Keith; Juluru, Krishna; Kersten, Kristopher; Rockenbach, Marcio Aloisio Bezerra Cavalcanti; Linguraru, Marius George; Haider, Masoom A.; AbdelMaseeh, Meena; Rieke, Nicola; Damasceno, Pablo F.; Silva, Pedro Mario Cruz E.; Wang, Pochuan; Xu, Sheng; Kawano, Shuichi; Sriswasdi, Sira; Park, Soo Young; Grist, Thomas M.; Buch, Varun; Jantarabenjakul, Watsamon; Wang, Weichung; Tak, Won Young; Li, Xiang; Lin, Xihong; Kwon, Young Joon; Quraini, Abood; Feng, Andrew; Priest, Andrew N.; Turkbey, Baris; Glicksberg, Benjamin; Bizzo, Bernardo; Kim, Byung Seok; Tor-Diez, Carlos; Lee, Chia-Cheng; Hsu, Chia-Jung; Lin, Chin; Lai, Chiu-Ling; Hess, Christopher P.; Compas, Colin; Bhatia, Deepeksha; Oermann, Eric K.; Leibovitz, Evan; Sasaki, Hisashi; Mori, Hitoshi; Yang, Isaac; Sohn, Jae Ho; Murthy, Krishna Nand Keshava; Fu, Li-Chen; Furtado de Mendonca, Matheus Ribeiro; Fralick, Mike; Kang, Min Kyu; Adil, Mohammad; Gangai, Natalie; Vateekul, Peerapon; Elnajjar, Pierre; Hickman, Sarah; Majumdar, Sharmila; McLeod, Shelley L.; Reed, Sheridan; Graf, Stefan; Harmon,Stephanie; Kodama, Tatsuya; Puthanakit, Thanyawee; Mazzulli, Tony; de Lavor, Vitor Lima; Rakvongthai, Yothin; Lee, Yu Rim; Wen, Yuhong; Gilbert, Fiona J.; Flores, Mona G.; Li, Quanzheng
  3. Nature medicine. 2021, Oct; 27(10): 1735-1743.
  1. 14.   Deconstructing the Treatment Effect of Remdesivir in the Adaptive COVID-19 Treatment Trial-1: Implications for Critical Care Resource Utilization
  2. Fintzi, Jonathan; Bonnett,Tyler; Sweeney, Daniel A; Huprikar, Nikhil A; Ganesan, Anuradha; Frank, Maria G; McLellan, Susan L F; Dodd, Lori E; Tebas, Pablo; Mehta, Aneesh K
  3. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021, Aug 19;
  1. 15.   TPM, FPKM, or Normalized Counts? A Comparative Study of Quantification Measures for the Analysis of RNA-seq Data from the NCI Patient-Derived Models Repository
  2. Zhao, Yingdong; Li, Ming-Chung; Konaté, Mariam M; Chen,Li; Das,Biswajit; Karlovich,Chris; Williams,Mickey; Evrard,Yvonne; Doroshow, James H; McShane, Lisa M
  3. Journal of translational medicine. 2021, Jun 22; 19(1): 269.
  1. 16.   Discovery and Optimization of 2H-1 lambda(2)-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer
  2. Rohde, Jason M.; Karavadhi, Surendra; Pragani, Rajan; Liu, Li; Fang, Yuhong; Zhang, Weihe; McIver, Andrew; Zheng, Hongchao; Liu, Qingyang; Davis, Mindy; Urban, Daniel J.; Lee, Tobie D.; Cheff, Dorian M.; Hollingshead,Melinda; Henderson, Mark J.; Martinez, Natalia J.; Brimacombe, Kyle R.; Yasgar, Adam; Zhao, Wei; Klumpp-Thomas, Carleen; Michael, Sam; Covey, Joseph; Moore,Bill; Stott, Gordon M.; Li, Zhuyin; Simeonov, Anton; Jadhav, Ajit; Frye, Stephen; Hall, Matthew D.; Shen, Min; Wang, Xiaodong; Patnaik, Samarjit; Boxer, Matthew B.
  3. Journal of Medicinal Chemistry. 2021, Apr 22; 64(8): 4913-4946.
  1. 17.   Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
  2. Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen,Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A.; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H.
  3. Nature Genetics. 2021, Jan; 53(1): 86-99.
  1. 18.   Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties
  2. Rai, Ganesha; Urban, Daniel J.; Mott, Bryan T.; Hu, Xin; Yang, Shyh-Ming; Benavides, Gloria A.; Johnson, Michelle S.; Squadrito, Giuseppe L.; Brimacombe, Kyle R.; Lee, Tobie D.; Cheff, Dorian M.; Zhu, Hu; Henderson, Mark J.; Pohida, Katherine; Sulikowski, Gary A.; Dranow, David M.; Kabir, Md; Shah, Pranav; Padilha, Elias; Tao, Dingyin; Fang, Yuhong; Christov, Plamen P.; Kim, Kwangho; Jana, Somnath; Muttil, Pavan; Anderson, Tamara; Kunda, Nitesh K.; Hathaway, Helen J.; Kusewitt, Donna F.; Oshima, Nobu; Cherukuri, Murali; Davies, Douglas R.; Norenberg, Jeffrey P.; Sklar, Larry A.; Moore, William J.; Dang, Chi; Stott,Gordon; Neckers, Leonard; Flint,Andrew; Darley-Usmar, Victor M.; Simeonov, Anton; Waterson, Alex G.; Jadhav, Ajit; Hall, Matthew D.; Maloney, David J.
  3. JOURNAL OF MEDICINAL CHEMISTRY. 2020, OCT 8; 63(19): 10984-11011.
  1. 19.   Particle Size Distributions for Cellulose Nanocrystals Measured by Transmission Electron Microscopy: An Interlaboratory Comparison
  2. Meija, Juris; Bushell, Michael; Couillard, Martin; Beck, Stephanie; Bonevich, John; Cui, Kai; Foster, Johan; Will, John; Fox, Douglas; Cho, Whirang; Heidelmann, Markus; Park, Byong Chon; Park, Yun Chang; Ren, Lingling; Xu, Li; Stefaniak, Aleksandr B.; Knepp, Alycia K.; Theissmann, Ralf; Purwin, Horst; Wang,Ziqiu; De Val Alda,Natalia; Johnston, Linda J.
  3. ANALYTICAL CHEMISTRY. 2020, OCT 6; 92(19): 13434-13442.
  1. 20.   Single cell-derived primary rectal carcinoma cell lines reflect intratumor heterogeneity associated with treatment response
  2. Braun, Rüdiger; Anthuber, Lena; Hirsch, Daniela; Wangsa, Darawalee; Lack,Justin; McNeil, Nicole E; Heselmeyer-Haddad, Kerstin; Torres, Irianna; Wangsa, Danny; Brown, Markus A; Tubbs, Anthony; Auslander, Noam; Gertz, E Michael; Brauer, Philip R; Cam,Maggie; Sackett, Dan; Habermann, Jens K; Nussenzweig, Andre; Ruppin, Eytan; Zhang, Zhongqiu; Rosenberg, Daniel W; Ried, Thomas
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020, JUL; 26(13): 3468-3480.
  1. 21.   The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps
  2. Sutherland, Vicki L; McQueen, Charlene A; Mendrick, Donna; Gulezian, Donna; Cerniglia, Carl; Foley, Steven; Forry, Sam; Khare, Sangeeta; Liang, Xue; Manautou, Jose E; Tweedie, Donald; Young,Howard; Alekseyenko, Alexander V; Burns, Frank; Dietert, Rod; Wilson, Alan; Chen, Connie
  3. Toxicological sciences : an official journal of the Society of Toxicology. 2020, Jul 01; 176(1): 1-10.
  1. 22.   Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
  2. Evrard,Yvonne; Srivastava, Anuj; Randjelovic, Jelena; Consortium, Nci PDXNet; Doroshow, James H; Dean, Dennis A; Morris, Jeffrey S; Chuang, Jeffrey H
  3. Cancer research. 2020, JUN 1; 80(11): 2286-2297.
  1. 23.   Fast and accurate brain T-2 relaxation time quantification in animal models calibrated using gel phantoms and in vivo data suitable for imaging at a biosafety level 4 environment
  2. Castro, Marcelo A.; Laux, Joseph; Friel, Harry; Solomon,Jeffrey; Byrum, Russell; Rojas, Oscar; Thomasson, David; Bollinger, Laura; Hammoud, Dima; Lee, Ji Hyun
  3. MEDICAL IMAGING 2020: PHYSICS OF MEDICAL IMAGING. 2020, 11312 1131233.
  1. 24.   (Q)SAR Models of HIV-1 Protein Inhibition by Drug-Like Compounds
  2. Stolbov, Leonid A; Druzhilovskiy, Dmitry S; Filimonov, Dmitry A; Nicklaus,Marc; Poroikov, Vladimir V
  3. Molecules (Basel, Switzerland). 2020, Jan 1; 25(1):
  1. 25.   A spontaneously metastatic model of bladder cancer: imaging characterization
  2. Tatum, James L; Kalen,Joseph; Jacobs, Paula M; Ileva,Lilia; Riffle,Lisa; Hollingshead,Melinda; Doroshow, James H
  3. Journal of translational medicine. 2019, Dec 19; 17(1): 425.
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