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  1. 1.   TnIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin
  2. Torres-Ayuso,Pedro; An, Elvira; Nyswaner,Katherine; Bensen,Ryan; Ritt,Daniel; Specht,Suzanne; Das,Sudipto; Andresson,Thorkell; Cachau,Raul; Liang, Roger J.; Ries,Amy; Robinson,Christina; Difilippantonio,Simone; Gouker,Brad; Gouker,Brad; Karim,Baktiar; Miller, Chad J.; Turk, Benjamin E.; Morrison,Deborah; Brognard,John
  3. Cancer Discovery. 2021, Jun; 11(6): 1411-1423.
  1. 2.   Phosphorylation of SMURF2 by ATM exerts a negative feedback control of DNA damage response
  2. Tang, Liu-Ya; Thomas, Adam; Zhou, Ming; Zhang, Ying E
  3. The Journal of biological chemistry. 2020, Dec 25; 295(52): 18485-18493.
  1. 3.   LSH mediates gene repression through macroH2A deposition
  2. Ni,Kai; Ren, Jianke; Xu,Xiaoping; He,Yafeng; Finney, Richard; Braun, Simon M. G.; Hathaway, Nathaniel A.; Crabtree, Gerald R.; Muegge,Kathrin
  3. NATURE COMMUNICATIONS. 2020, NOV 6; 11(1):
  1. 4.   Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome
  2. Chittori, Sagar; Hong, Jingjun; Bai, Yawen; Subramaniam,Sriram
  3. Nucleic acids research. 2019, SEP 26; 47(17): 9400-9409.
  1. 5.   Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS
  2. Tao, Y. G.; Liu, S.; Briones, V.; Geiman, T. M.; Muegge, K.
  3. Nucleic Acids Research. 2011, Dec; 39(22): 9508-9520.
  1. 6.   Structure and function of RapA: A bacterial Swi2/Snf2 protein required for RNA polymerase recycling in transcription
  2. Jin, D. J.; Zhou, Y. N.; Shaw, G.; Ji, X. H.
  3. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms. 2011, Sep; 1809(9): 470-475.
  1. 7.   Lymphoid-Specific Helicase (HELLS) Is Essential for Meiotic Progression in Mouse Spermatocytes
  2. Zeng, W. X.; Baumann, C.; Schmidtmann, A.; Honaramooz, A.; Tang, L.; Bondareva, A.; Dores, C.; Fan, T.; Xi, S. C.; Geiman, T.; Rathi, R.; de Rooij, D.; De La Fuente, R.; Muegge, K.; Dobrinski, I.
  3. Biology of Reproduction. 2011, Jun; 84(6): 1235-1241.
  1. 8.   Sequence analysis of the shelterin telomere protection complex genes in dyskeratosis congenita
  2. Savage, S. A.; Giri, N.; Jessop, L.; Pike, K.; Plona, T.; Burdett, L.; Alter, B. P.
  3. Journal of Medical Genetics. 2011, Apr; 48(4): 285-288.
  1. 9.   Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences
  2. Tao, Y. G.; Xi, S. C.; Shan, J. G.; Maunakea, A.; Che, A.; Briones, V.; Lee, E. Y.; Geiman, T.; Huang, J. Q.; Stephens, R.; Leighty, R. M.; Zhao, K. J.; Muegge, K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2011, Apr; 108(14): 5626-5631.
  1. 10.   Back to the Future: Proceedings From the 2010 NF Conference
  2. Huson, S. M.; Acosta, M. T.; Belzberg, A. J.; Bernards, A.; Chernoff, J.; Cichowski, K.; Evans, D. G.; Ferner, R. E.; Giovannini, M.; Korf, B. R.; Listernick, R.; North, K. N.; Packer, R. J.; Parada, L. F.; Peltonen, J.; Ramesh, V.; Reilly, K. M.; Risner, J. W.; Schorry, E. K.; Upadhyaya, M.; Viskochil, D. H.; Zhu, Y. A.; Hunter-Schaedle, K.; Giancotti, F. G.
  3. American Journal of Medical Genetics Part A. 2011, Feb; 155A(2): 307-321.
  1. 11.   Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/beta-Catenin Signaling Pathway
  2. Saydam, O.; Shen, Y. P.; Wurdinger, T.; Senol, O.; Boke, E.; James, M. F.; Tannous, B. A.; Stemmer-Rachamimov, A. O.; Yi, M.; Stephens, R. M.; Fraefel, C.; Gusella, J. F.; Krichevsky, A. M.; Breakefield, X. O.
  3. Molecular and Cellular Biology. 2009 29(21): 5923-5940.
  1. 12.   EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation
  2. Ding, W.; Li, C. X.; Hu, T. H.; Graves-Deal, R.; Fotia, A. B.; Weissman, A. M.; Coffey, R. J.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2008 105(36): 13433-13438.
  1. 13.   DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development
  2. Fan, T.; Schmidtmann, A.; Xi, S.; Briones, V.; Zhu, H. M.; Suh, H. C.; Gooya, J.; Keller, J. R.; Xu, H.; Roayaei, J.; Anver, M.; Ruscetti, S.; Muegge, K.
  3. Epigenetics. 2008 3(3): 134-142.
  1. 14.   Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription
  2. Shaw, G.; Gan, J. H.; Zhou, Y. N.; Zhi, H. J.; Subburaman, P.; Zhang, R. G.; Joachimiak, A.; Jin, D. J.; Ji, X. H.
  3. Structure. 2008 16(9): 1417-1427.
  1. 15.   Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells
  2. De la Fuente, R.; Baumann, C.; Fan, T.; Schmidtmann, A.; Dobrinski, I.; Muegge, K.
  3. Nature Cell Biology. 2006, Dec; 8(12): 1448-U85.
  1. 16.   Lsh is involved in de novo methylation of DNA
  2. Zhu, H. M.; Geiman, T. M.; Xi, S. C.; Jiang, Q.; Schmidtmann, A.; Chen, T. P.; Li, E.; Muegge, K.
  3. Embo Journal. 2006, JAN 25; 25(2): 335-345.
  1. 17.   Lsh controls silencing of the imprinted Cdkn1c gene
  2. Fan, T.; Hagan, J. P.; Kozlov, S. V.; Stewart, C. L.; Muegge, K.
  3. Development. 2005, FEB; 132(4): 635-644.
  1. 18.   Lsh, an epigenetic guardian of repetitive elements
  2. Huang, J. Q.; Fan, T.; Yan, Q. S.; Zhu, H. M.; Fox, S.; Issaq, H. J.; Best, L.; Gangi, L.; Munroe, D.; Muegge, K.
  3. Nucleic Acids Research. 2004 32(17): 5019-5028.
  1. 19.   Lsh, a modulator of CpG methylation, is crucial for normal histone methylation
  2. Yan, Q. S.; Huang, J. Q.; Fan, T.; Zhu, H. M.; Muegge, K.
  3. Embo Journal. 2003 22(19): 5154-5162.
  1. 20.   Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin
  2. Yan, Q. S.; Cho, E.; Lockett, S.; Muegge, K.
  3. Molecular and Cellular Biology. 2003 23(23): 8416-8428.
  1. 21.   Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis
  2. Fan, T.; Yan, Q. S.; Huang, J. Q.; Austin, S.; Cho, E.; Ferris, D.; Muegge, K.
  3. Cancer Research. 2003 63(15): 4677-4683.
  1. 22.   Lsh, a SNF2 family member, is required for normal murine development
  2. Geiman, T. M.; Tessarollo, L.; Anver, M. R.; Kopp, J. B.; Ward, J. M.; Muegge, K.
  3. Biochimica Et Biophysica Acta-General Subjects. 2001 1526(2): 211-220.
  1. 23.   Lsh, a member of the SNF2 family, is required for genome-wide methylation
  2. Dennis, K.; Fan, T.; Geiman, T.; Yan, Q. S.; Muegge, K.
  3. Genes & Development. 2001 15(22): 2940-2944.
  1. 24.   Establishment of primary vestibular schwannoma cultures from neurofibromatosis type-2 patients
  2. Hung, G.; Faudoa, R.; Li, X. K.; Xeu, Z.; Brackmann, D. E.; Hitselberg, W.; Saleh, E.; Lee, F.; Gutmann, D. H.; Slattery, W. I.; Rhim, J. S.; Lim, D.
  3. International Journal of Oncology. 1999 14(3): 409-415.
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