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  1. 1.   Chronic Exposure to Nitric Oxide Induces P53 Mutations and Malignant-like Features in Human Breast Epithelial Cells
  2. Cheng,Robert; Burkett,Sandra; Ambs, Stefan; Moody, Terry; Wink,David; Ridnour,Lisa
  3. Biomolecules. 2023, Feb 07; 13(2):
  1. 2.   Alpha globin gene copy number and incident ischemic stroke risk among Black Americans
  2. Ruhl, A Parker; Jeffries, Neal; Yang, Yu; Brooks, Steven D; Naik, Rakhi P; Pecker, Lydia H; Mott, Bryan T; Winkler,Cheryl; Armstrong, Nicole D; Zakai, Neil A; Gutierrez, Orlando M; Judd, Suzanne E; Howard, Virginia J; Howard, George; Irvin, Marguerite R; Cushman, Mary; Ackerman, Hans C
  3. Frontiers in Stroke. 2023 2
  1. 3.   HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCe Activation
  2. Mancardi, Daniele; Pagliaro, Pasquale; Ridnour,Lisa; Tocchetti, Carlo G; Miranda, Katrina; Juhaszova, Magdalena; Sollott, Steven J; Wink,David; Paolocci, Nazareno
  3. Antioxidants (Basel, Switzerland). 2022, Feb 14; 11(2):
  1. 4.   Nitric Oxide in Macrophage Immunometabolism: Hiding in Plain Sight
  2. Palmieri,Erika; McGinity,Chris; Wink,David; McVicar,Daniel
  3. Metabolites. 2020, NOV; 10(11):
  1. 5.   A divergent mode of activation of a nitrosyl iron complex with unusual antiangiogenic activity
  2. Carvalho, Edinilton Muniz; Ridnour,Lisa; Júnior, Florêncio Sousa Gouveia; Cabral, Pedro Henrique Bezerra; do Nascimento, Nilberto Robson Falcão; Wink, David A; Franco, Douglas W; de Medeiros, Mayara Jane Campos; de Lima Pontes, Daniel; Longhinotti, Elisane; de Freitas Paulo, Tércio; Bernardes-Génisson, Vania; Chauvin, Remi; Sousa, Eduardo Henrique Silva; Lopes, Luiz Gonzaga de França
  3. Journal of inorganic biochemistry. 2020, SEP; 210: 111133.
  1. 6.   Nitric Oxide Donor DETA/NO Inhibits the Growth of Endometrial Cancer Cells by Upregulating the Expression of RASSF1 and CDKN1A
  2. Waheed, Sana; Cheng, Robert Ys; Casablanca, Yovanni; Maxwell, G Larry; Wink,David; Syed, Viqar
  3. Molecules (Basel, Switzerland). 2019, Oct 16; 24(20): pii: E3722..
  1. 7.   Role of nitric oxide in pancreatic cancer cells exhibiting the invasive phenotype
  2. Fujita, Mayumi; Somasundaram,Veena; Basudhar,Debashree; Cheng,Robert; Ridnour,Lisa; Higuchi, Harumi; Imadome, Kaori; No, Jae Hong; Bharadwaj, Gaurav; Wink,David
  3. REDOX BIOLOGY. 2019, Apr; 22
  1. 8.   Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer
  2. Basudhar, Debashree; Glynn, Sharon A; Greer, Madison; Somasundaram, Veena; No, Jae Hong; Scheiblin, David; Garrido, Pablo; Heinz, Will; Ryan, Aideen E; Weiss, Jonathan M; Cheng, Robert Y S; Ridnour, Lisa; Lockett, Stephen; McVicar, Daniel; Ambs, Stefan; Wink, David
  3. Proceedings of the National Academy of Sciences of the United States of America. 2017, Dec 05; 114(49): 13030-13035.
  1. 9.   The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine
  2. Cortese-Krott, Miriam M.; Koning, Anne; Kuhnle, Gunter G. C.; Nagy, Peter; Bianco, Christopher L.; Pasch, Andreas; Wink, David; Fukuto, Jon M.; Jackson, Alan A.; van Goor, Harry; Olson, Kenneth R.; Feelisch, Martin
  3. Antioxidants & Redox Signaling. 2017, Oct 1; 27(10): 684-712.
  1. 10.   JS-K, a nitric oxide prodrug, induces DNA damage and apoptosis in HBV-positive hepatocellular carcinoma HepG2.2.15 cell
  2. Liu, Zhengyun; Li, Guangmin; Gou, Ying; Xiao, Dongyan; Luo, Guo; Saavedra, Joseph; Liu, Jie; Wang, Huan
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017, Aug; 92: 989-997.
  1. 11.   The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation
  2. Heckler, Max; Osterberg, Nadja; Guenzle, Jessica; Thiede-Stan, Nina Kristin; Reichardt, Wilfried; Weidensteiner, Claudia; Saavedra, Joseph; Weyerbrock, Astrid
  3. Tumour Biology. 2017, Jun 27; 39(6): 1-11.
  1. 12.   Nitric Oxide Synthase-2-Derived Nitric Oxide Drives Multiple Pathways of Breast Cancer Progression
  2. Basudhar, Debashree; Somasundaram, Veena; de Oliveira, Graciele Almeida; Kesarwala, Aparna; Heinecke, Julie L.; Cheng, Robert Y.; Glynn, Sharon A.; Ambs, Stefan; Wink, David; Ridnour, Lisa
  3. ANTIOXIDANTS & REDOX SIGNALING. 2017, Jun 20; 26(18): 1044-1058.
  1. 13.   Inducible Nitric Oxide Synthase in the Carcinogenesis of Gastrointestinal Cancers
  2. de Oliveira, G. A.; Cheng, R. Y.; Ridnour, L. A.; Basudhar, D.; Somasundaram, V.; McVicar, D. W.; Monteiro, H. P.; Wink, D. A.
  3. Antioxidants & Redox Signaling. 2017, Jun 20; 26(18): 1059-1077.
  1. 14.   NOS2 as an Emergent Player in Progression of Cancer
  2. Thomas, Douglas D.; Wink, David
  3. Antioxidants & Redox Signaling. 2017, Jun 10; 26(17): 963-965.
  1. 15.   Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1
  2. Kovacevic, Z.; Sahni, S.; Lok, H.; Davies, M. J.; Wink, David; Richardson, D. R.
  3. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 2017, May; 1861(5 Pt A): 995-999.
  1. 16.   Effects of JS-K, a novel anti-cancer nitric oxide prodrug, on gene expression in human hepatoma Hep3B cells
  2. Dong, Ray; Wang, Xueqian; Wang, Huan; Liu, Zhengyun; Liu, Jie; Saavedra, Joseph
  3. BIOMEDICINE & PHARMACOTHERAPY. 2017, Apr; 88: 367-373.
  1. 17.   The Role of Estrogen Receptor alpha and beta in Regulating Vascular Smooth Muscle Cell Proliferation is Based on Sex
  2. Hogg, M. E.; Vavra, A. K.; Banerjee, M. N.; Martinez, J.; Jiang, Q.; Keefer, L. K.; Chambon, P.; Kibbe, M. R.
  3. Journal of Surgical Research. 2012, Mar; 173(1): E1-E10.
  1. 18.   Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-p-activated nitric oxide donor PABA/NO in malignant gliomas
  2. Kogias, E.; Osterberg, N.; Baumer, B.; Psarras, N.; Koentges, C.; Papazoglou, A.; Saavedra, J. E.; Keefer, L. K.; Weyerbrock, A.
  3. International Journal of Cancer. 2012, Mar; 130(5): 1184-1194.
  1. 19.   Diazeniumdiolated carbamates: A novel class of nitric oxide donors
  2. Nandurdikar, R. S.; Maciag, A. E.; Cao, Z.; Keefer, L. K.; Saavedra, J. E.
  3. Bioorganic & Medicinal Chemistry. 2012, Mar; 20(6): 2025-2029.
  1. 20.   JS-K, a Glutathione S-Transferase-Activated Nitric Oxide Donor With Antineoplastic Activity in Malignant Gliomas
  2. Weyerbrock, A.; Osterberg, N.; Psarras, N.; Baumer, B.; Kogias, E.; Werres, A.; Bette, S.; Saavedra, J. E.; Keefer, L. K.; Papazoglou, A.
  3. Neurosurgery. 2012, Feb; 70(2): 497-510.
  1. 21.   Insights into the effect of nitric oxide and its metabolites nitrite and nitrate at inhibiting neointimal hyperplasia
  2. Vavra, A. K.; Havelka, G. E.; Martinez, J.; Lee, V. R.; Fu, B.; Jiang, Q.; Keefer, L. K.; Kibbe, M. R.
  3. Nitric Oxide-Biology and Chemistry. 2011, Jun; 25(1): 22-30.
  1. 22.   Nitric Oxide Inhibits Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia by Increasing the Ubiquitination and Degradation of UbcH10
  2. Tsihlis, N. D.; Oustwani, C. S.; Vavra, A. K.; Jiang, Q.; Keefer, L. K.; Kibbe, M. R.
  3. Cell Biochemistry and Biophysics. 2011, Jun; 60(1-2): 89-97.
  1. 23.   Poly(diol-co-citrate)s as Novel Elastomeric Perivascular Wraps for the Reduction of Neointimal Hyperplasia
  2. Serrano, M. C.; Vavra, A. K.; Jen, M.; Hogg, M. E.; Murar, J.; Martinez, J.; Keefer, L. K.; Ameer, G. A.; Kibbe, M. R.
  3. Macromolecular Bioscience. 2011, May; 11(5): 700-709.
  1. 24.   JS-K, a nitric oxide-releasing prodrug, induces breast cancer cell death while sparing normal mammary epithelial cells
  2. McMurtry, V.; Saavedra, J. E.; Nieves-Alicea, R.; Simeone, A. M.; Keefer, L. K.; Tari, A. M.
  3. International Journal of Oncology. 2011, Apr; 38(4): 963-971.
  1. 25.   Age-related properties of the tumour vasculature in renal cell carcinoma
  2. Meehan, B.; Appu, S.; St Croix, B.; Rak-Poznanska, K.; Klotz, L.; Rak, J.
  3. Bju International. 2011, Feb; 107(3): 416-424.
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