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  1. 1.   ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
  2. Su, Wenjing; Mukherjee, Radha; Yaeger, Rona; Son, Jieun; Xu, Jianing; Na, Na; Merna Timaul, Neilawattie; Hechtman, Jaclyn; Paroder, Viktoriya; Lin, Mika; Mattar, Marissa; Qiu, Juan; Chang, Qing; Zhao, Huiyong; Zhang, Jonathan; Little, Megan; Adachi, Yuta; Han, Sae-Won; Taylor, Barry S; Ebi, Hiromichi; Abdel-Wahab, Omar; de Stanchina, Elisa; Rudin, Charles M; Jänne, Pasi A; McCormick, Frank; Yao, Zhan; Rosen, Neal
  3. Molecular Cell. 2022, May 14;
  1. 2.   A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor
  2. Huang, Yongjian; Ognjenovic,Jana; Karandur, Deepti; Miller, Kate; Merk,Alan; Subramaniam, Sriram; Kuriyan, John
  3. eLife. 2021, Nov 30; 10
  1. 3.   Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer
  2. Choudhary, Shruti; Doshi, Arpit; Luckett-Chastain, Lerin; Ihnat, Michael; Hamel,Ernest; Mooberry, Susan L.; Gangjee, Aleem
  3. Bioogranic & Medicinal Chemistry. 2021, Apr 1; 35
  1. 4.   Delayed onset of inherited ALS by deletion of the BDNF receptor TrkB.T1 is non-cell autonomous
  2. Yanpallewar,Sudhirkumar; Fulgenzi, Gianluca; Tomassoni Ardori,Francesco; Barrick,Colleen; Tessarollo,Lino
  3. EXPERIMENTAL NEUROLOGY. 2021, Mar; 337
  1. 5.   New Therapeutic Opportunities for the Treatment of Squamous Cell Carcinomas: A Focus on Novel Driver Kinases
  2. Bensen, Ryan; Brognard,John
  3. International Journal of Molecular Sciences. 2021, Mar; 22(6):
  1. 6.   Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation
  2. Hong,Jaewoo; Wuest, Todd R; Min,Yongfen; Lin,Charles
  3. Cancers. 2019, Nov; 11(11): pii: E1653..
  1. 7.   Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo [3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple -acting angiokinase inhibition as antitumor agents
  2. Pavana, Roheeth Kumar; Choudhary, Shruti; Bastian, Anja; Ihnat, Michael A.; Bai, Ruoli; Hamel, Ernest; Gangjee, Aleem
  3. BIOORGANIC & MEDICINAL CHEMISTRY. 2017, Jan 15; 25(2): 545-556.
  1. 8.   Vascular endothelial growth factor receptor 2 inhibition in-vivo affects tumor vasculature in a tumor type-dependent way and downregulates vascular endothelial growth factor receptor 2 protein without a prominent role for miR-296
  2. Langenkamp, E.; Zwiers, P. J.; Moorlag, H. E.; Leenders, W. P.; Croix, B. S.; Molema, G.
  3. Anti-Cancer Drugs. 2012, Feb; 23(2): 161-172.
  1. 9.   Non-SH2/PDZ reverse signaling by ephrins
  2. Daar, I. O.
  3. Seminars in Cell & Developmental Biology. 2012, Feb; 23(1): 65-74.
  1. 10.   Eph/ephrin signaling in cell-cell and cell-substrate adhesion
  2. Singh, A.; Winterbottom, E.; Daar, I. O.
  3. Frontiers in Bioscience-Landmark. 2012, Jan; 17: 473-497.
  1. 11.   Peptide Structure Stabilization by Membrane Anchoring and its General Applicability to the Development of Potent Cell-Permeable Inhibitors
  2. Johannessen, L.; Remsberg, J.; Gaponenko, V.; Adams, K. M.; Barchi, J. J.; Tarasov, S. G.; Jiang, S.; Tarasova, N. I.
  3. Chembiochem. 2011, Apr; 12(6): 914-921.
  1. 12.   Role of Phosphatidylinositol 3-Kinase in Friend Spleen Focus-Forming Virus-Induced Erythroid Disease
  2. Umehara, D.; Watanabe, S.; Ochi, H.; Anai, Y.; Ahmed, N.; Kannagi, M.; Hanson, C.; Ruscetti, S.; Nishigaki, K.
  3. Journal of Virology. 2010, Aug; 84(15): 7675-7682.
  1. 13.   Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models
  2. Taylor, J. G.; Cheuk, A. T.; Tsang, P. S.; Chung, J. Y.; Song, Y. K.; Desai, K.; Yu, Y. L.; Chen, Q. R.; Shah, K.; Youngblood, V.; Fang, J.; Kim, S. Y.; Yeung, C.; Helman, L. J.; Mendoza, A.; Ngo, V.; Staudt, L. M.; Wei, J. S.; Khanna, C.
  3. Journal of Clinical Investigation. 2009 119(11): 3395-3407.
  1. 14.   EphrinB1 controls cell-cell junctions through the Par polarity complex
  2. Lee, H. S.; Nishanian, T. G.; Mood, K.; Bong, Y. S.; Daar, I. O.
  3. Nature Cell Biology. 2008 10(8): 979-986.
  1. 15.   Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter
  2. Angeloni, D.; Danilkovitch-Miagkova, A.; Ivanova, T.; Braga, E.; Zabarovsky, E.; Lerman, M. I.
  3. Oncogene. 2007, Jul; 26(31): 4499-4512.
  1. 16.   Integrating signals from RTKs to ERK/MAPK
  2. McKay, M. M.; Morrison, D. K.
  3. Oncogene. 2007, May; 26(22): 3113-3121.
  1. 17.   Identification of the genes for kidney cancer: Opportunity for disease-specific targeted therapeutics
  2. Linehan, W. M.; Pinto, P. A.; Srinivasan, R.; Merino, M.; Choyke, P.; Choyke, L.; Coleman, J.; Toro, J.; Glenn, G.; Vocke, C.; Zbar, B.; Schmidt, L. S.; Bottaro, D.; Neckers, L.
  3. Clinical Cancer Research. 2007, Jan; 13(2): 671S-679S.
  1. 18.   Oncogenic met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling
  2. Mood, K.; Saucier, C.; Ishimura, A.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Journal of Cellular Physiology. 2006, APR; 207(1): 271-285.
  1. 19.   Friend spleen focus-forming virus transforms rodent fibroblasts in cooperation with a short form of the receptor tyrosine kinase Stk
  2. Nishigaki, K.; Hanson, C.; Jelacic, T.; Thompson, D.; Ruscetti, S.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, OCT 25; 102(43): 15488-15493.
  1. 20.   Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain
  2. Phan, J.; Shi, Z. D.; Burke, T. R.; Waugh, D. S.
  3. Journal of Molecular Biology. 2005, OCT 14; 353(1): 104-115.
  1. 21.   Activation of discoidin domain receptor 1 on CD14-positive pronchoalveolar lavage fluid cells induces chemokine production in idiopathic pulmonary fibrosis
  2. Matsuyama, W.; Watanabe, M.; Shirahama, Y.; Oonakahara, K. I.; Higashimoto, I.; Yoshimura, T.; Osame, M.; Arimura, K.
  3. Journal of Immunology. 2005, MAY 15; 174(10): 6490-6498.
  1. 22.   PKC delta plays opposite roles in growth mediated by wild-type Kit and an oncogenic Kit mutant
  2. Jelacic, T.; Linnekin, D.
  3. Blood. 2005, MAR 1; 105(5): 1923-1929.
  1. 23.   Synergistic growth of stem cell factor and granulocyte macrophage colony-stimulating factor involves kinase-dependent and -independent contributions from c-Kit
  2. Lennartsson, J.; Shivakrupa, R.; Linnekin, D.
  3. Journal of Biological Chemistry. 2004, OCT 22; 279(43): 44544-44553.
  1. 24.   The soluble sema domain of the RON receptor inhibits macrophage-stimulating protein-induced receptor activation
  2. Angeloni, D.; Danilkovitch-Miagkova, A.; Miagkov, A.; Leonard, E. J.; Lerman, M. I.
  3. Journal of Biological Chemistry. 2004 279(5): 3726-3732.
  1. 25.   Tyr-298 in ephrinB1 is critical for an interaction with the Grb4 adaptor protein
  2. Bong, Y. S.; Park, Y. H.; Lee, H. S.; Mood, K.; Ishimura, A.; Daar, I. O.
  3. Biochemical Journal. 2004 377(Part 2): 499-507.
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