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  1. 1.   Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells
  2. Larsen, Brian M; Cowan, Jennifer E; Wang, Yueqiang; Tanaka, Yu; Zhao, Yongge; Voisin, Benjamin; Constantinides, Michael G; Nagao, Keisuke; Belkaid, Yasmine; Awasthi,Roackie; Takahama, Yousuke; Bhandoola, Avinash
  3. Journal of immunology (Baltimore, Md. : 1950). 2019, AUG 1; 203(3): 686-695.
  1. 2.   CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease
  2. De Ravin, Suk See; Li, Linhong; Wu, Xiaolin; Choi, Uimook; Allen, Cornell; Koontz, Sherry; Lee, Janet; Theobald-Whiting, Narda; Chu, Jessica; Garofalo, Mary; Sweeney, Colin; Kardava, Lela; Moir, Susan; Viley, Angelia; Natarajan, Pachai; Su, Ling; Kuhns, Douglas; Zarember, Kol A.; Peshwa, Madhusudan V.; Malech, Harry L.
  3. SCIENCE TRANSLATIONAL MEDICINE. 2017, Jan 11; 9(372): eaah3480.
  1. 3.   Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
  2. Zenatti, P. P.; Ribeiro, D.; Li, W. Q.; Zuurbier, L.; Silva, M. C.; Paganin, M.; Tritapoe, J.; Hixon, J. A.; Silveira, A. B.; Cardoso, B. A.; Sarmento, L. M.; Correia, N.; Toribio, M. L.; Kobarg, J.; Horstmann, M.; Pieters, R.; Brandalise, S. R.; Ferrando, A. A.; Meijerink, J. P.; Durum, S. K.; Yunes, J. A.; Barata, J. T.
  3. Nature Genetics. 2011, Oct; 43(10): 932-U31.
  1. 4.   Implications for Gene Therapy-Limiting Expression of IL-2R gamma(c) Delineate Differences in Signaling Thresholds Required for Lymphocyte Development and Maintenance
  2. Orr, S. J.; Roessler, S.; Quigley, L.; Chan, T.; Ford, J. W.; O'Connor, G. M.; McVicar, D. W.
  3. Journal of Immunology. 2010, Aug; 185(3): 1393-1403.
  1. 5.   Hypomorphic Rag mutations can cause destructive midline granulomatous disease
  2. De Ravin, S. S.; Cowen, E. W.; Zarember, K. A.; Whiting-Theobald, N. L.; Kuhns, D. B.; Sandler, N. G.; Douek, D. C.; Pittaluga, S.; Poliani, P. L.; Lee, Y. N.; Notarangelo, L. D.; Wang, L.; Alt, F. W.; Kang, E. M.; Milner, J. D.; Niemela, J. E.; Fontana-Penn, M.; Sinal, S. H.; Malech, H. L.
  3. Blood. 2010, Aug; 116(8): 1263-1271.
  1. 6.   Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils
  2. Kang, E. M.; Choi, U.; Theobald, N.; Linton, G.; Priel, D. A. L.; Kuhns, D.; Malech, H. L.
  3. Blood. 2010, Jan; 115(4): 783-791.
  1. 7.   Self-inactivating Retroviral Vector-mediated Gene Transfer Induces Oncogene Activation and Immortalization of Primary Murine Bone Marrow Cells
  2. Bosticardo, M.; Ghosh, A.; Du, Y.; Jenkins, N. A.; Copeland, N. G.; C, otti
  3. Molecular Therapy. 2009 17(11): 1910-1918.
  1. 8.   Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34(+) cells
  2. Kim, Y. J.; Kim, Y. S.; Larochelle, A.; Renaud, G.; Wolfsberg, T. G.; Adler, R.; Donahue, R. E.; Hematti, P.; Hong, B. K.; Roayaei, J.; Akagi, K.; Riberdy, J. M.; Nienhuis, A. W.; Dunbar, C. E.; Persons, D. A.
  3. Blood. 2009 113(22): 5434-5443.
  1. 9.   Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
  2. Ott, M. G.; Schmidt, M.; Schwarzwaelder, K.; Stein, S.; Siler, U.; Koehl, U.; Glimm, H.; Kuhlcke, K.; Schilz, A.; Kunkel, H.; Naundorf, S.; Brinkmann, A.; Deichmann, A.; Fischer, M.; Ball, C.; Pilz, I.; Dunbar, C.; Du, Y.; Jenkins, N. A.; Copeland, N. G.; Luthi, U.; Hassan, M.; Thrasher, A. J.; Hoelzer, D.; von Kalle, C.; Seger, R.; Grez, M.
  3. Nature Medicine. 2006, Apr; 12(4): 401-409.
  1. 10.   Stat5a/b are essential for normal lymphoid development and differentiation
  2. Yao, Z. J.; Cui, Y. Z.; Watford, W. T.; Bream, J. H.; Yamaoka, K.; Hissong, B. D.; Li, D.; Durum, S. K.; Jiang, Q. O.; Bhandoola, A.; Hennighausen, L.; O'Shea, J. J.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, JAN 24; 103(4): 1000-1005.
  1. 11.   Retroviral transduction of IL-7R alpha into IL-7R alpha(-/-) bone marrow progenitors: correction of lymphoid deficiency and induction of neutrophilia
  2. Jiang, Q.; Li, W. Q.; Aiello, F. B.; Klarmann, K.; Keller, J. R.; Durum, S. K.
  3. Gene Therapy. 2005, DEC; 12(24): 1761-1768.
  1. 12.   Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells
  2. Calmels, B.; Ferguson, C.; Laukkanen, M. O.; Adler, R.; Faulhaber, M.; Kim, H. J.; Sellers, S.; Hematti, P.; Schmidt, M.; von Kalle, C.; Akagi, K.; Donahue, R. E.; Dunbar, C. E.
  3. Blood. 2005, OCT 1; 106(7): 2530-2533.
  1. 13.   Gene therapy insertional mutagenesis insights
  2. Dave, U. P.; Jenkins, N. A.; Copeland, N. G.
  3. Science. 2004 303(5656): 333-333.
  1. 14.   Transcription start regions in the human genome are favored targets for MLV integration
  2. Wu, X. L.; Li, Y.; Crise, B.; Burgess, S. M.
  3. Science. 2003 300(5626): 1749-1751.
  1. 15.   In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals
  2. McCauslin, C. S.; Wine, J.; Cheng, L. Z.; Klarmann, K. D.; Candotti, F.; Clausen, P. A.; Spence, S. E.; Keller, J. R.
  3. Blood. 2003 102(3): 843-848.
  1. 16.   Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways
  2. Nagy, Z. S.; Wang, Y. L.; Erwin-Cohen, R. A.; Aradi, J.; Monia, B.; Wang, L. H.; Stepkowski, S. M.; Rui, H.; Kirken, R. A.
  3. Journal of Leukocyte Biology. 2002 72(4): 819-828.
  1. 17.   The role of cytokines in lymphocyte homeostasis
  2. Khaled, A. R.; Durum, S. K.
  3. Biotechniques. 2002 (Suppl. S): 40-45.
  1. 18.   Control of chromatin accessibility for V(D)J recombination by interleukin-7
  2. Huang, J. Q.; Muegge, K.
  3. Journal of Leukocyte Biology. 2001 69(6): 907-911.
  1. 19.   The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase
  2. Jhappan, C.; Yusufzai, T. M.; Anderson, S.; Anver, M. R.; Merlino, G.
  3. Molecular and Cellular Biology. 2000 20(11): 4075-4083.
  1. 20.   The interleukin 7 receptor is required for T cell receptor gamma locus accessibility to the V(D)J recombinase
  2. Schlissel, M. S.; Durum, S. D.; Muegge, K.
  3. Journal of Experimental Medicine. 2000 191(6): 1045-1050.
  1. 21.   Engraftment of Ex Vivo Expanded and Cycling Human Cord Blood Hematopoietic Progenitor Cells in Scid Mice
  2. Spence, S. E.; Keller, J. R.; Ruscetti, F. W.; McCauslin, C. S.; Gooya, J. M.; Funakoshi, S.; Longo, D. L.; Murphy, W. J.
  3. Experimental Hematology. 1998 26(6): 507-514.
  1. 22.   Antitumor Effects of Nonconjugated Murine Lym-2 and Human-Mouse Chimeric Cll-1 Monoclonal Antibodies Against Various Human Lymphoma Cell Lines in Vitro and in Vivo
  2. Funakoshi, S.; Hirano, A.; Beckwith, M.; Asai, O.; Jorgensen, G.; Tian, Z. G.; Hornick, J. L.; Hu, P. S.; Khawli, L. A.; Epstein, A. L.; Longo, D. L.; Murphy, W. J.
  3. Blood. 1997 90(8): 3160-3166.
  1. 23.   Il-7 Receptor and Vdj Recombination - Trophic Versus Mechanistic Actions
  2. Candeias, S.; Muegge, K.; Durum, S. K.
  3. Immunity. 1997 6(5): 501-508.
  1. 24.   Effects of Cd40 Stimulation in the Prevention of Human Ebv-Lymphomagenesis
  2. Funakoshi, S.; Taub, D. D.; Asai, O.; Hirano, A.; Ruscetti, F. W.; Longo, D. L.; Murphy, W. J.
  3. Leukemia & Lymphoma. 1997 24(3-4): 187 ff..
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