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  1. 1.   Tumor resistance to anti-mesothelin CAR-T cells caused by binding to shed mesothelin is overcome by targeting a juxtamembrane epitope
  2. Liu, X F; Onda, M; Schlomer,Jerome; Bassel,Laura; Kozlov,Serguei; Tai, C-H; Zhou, Q; Liu, W; Tsao, H-E; Hassan, R; Ho, M; Pastan, I
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Jan 23; 121(4): e2317283121.
  1. 2.   UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer
  2. Harrington, Brittney S; Kamdar, Rahul; Ning, Franklin; Korrapati, Soumya; Caminear, Michael W; Hernandez, Lidia F; Butcher,Donna; Edmondson,Elijah; Traficante, Nadia; Hendley, Joy; Gough, Madeline; Rogers, Rebecca; Lourie, Rohan; Shetty,Jyoti; Tran,Bao; Abdelmaksoud, Abdalla; Nag, Madhu Lal; Mazan-Mamczarz, Krystyna; House, Carrie D; Hooper, John D; Annunziata, Christina M; Elloumi,Fathi
  3. Journal of Experimental & Clinical Cancer Research : CR. 2023, Oct 19; 42(1): 270.
  1. 3.   NF-kB Signaling Modulates miR-452-5p and miR-335-5p Expression to Functionally Decrease Epithelial Ovarian Cancer Progression in Tumor-Initiating Cells
  2. Kamdar, Rahul D; Harrington, Brittney S; Attar, Emma; Korrapati, Soumya; Shetty,Jyoti; Zhao,Yongmei; Tran,Bao; Wong, Nathan; House, Carrie D; Annunziata, Christina M
  3. International Journal of Molecular Sciences. 2023, Apr 25; 24(9):
  1. 4.   A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer
  2. Manzo, Julia; Puhalla, Shannon; Pahuja, Shalu; Ding, Fei; Lin, Yan; Appleman, Leonard; Tawbi, Hussein; Stoller, Ronald; Lee, James J; Diergaarde, Brenda; Kiesel, Brian F; Yu, Jing; Tan, Antoinette R; Belani, Chandra P; Chew, Helen; Garcia, Agustin A; Morgan, Robert J; Wahner Hendrickson, Andrea E; Visscher, Daniel W; Hurley, Rachel M; Kaufmann, Scott H; Swisher, Elizabeth M; Oesterreich, Steffi; Katz, Tiffany; Ji,Jay; Zhang, Yiping; Parchment, Ralph E; Chen, Alice; Duan, Wenrui; Giranda, Vincent; Shepherd, Stacie P; Ivy, S Percy; Chu, Edward; Beumer, Jan H
  3. Cancer Chemotherapy and Pharmacology. 2022, Apr 18; 89(5): 721-735.
  1. 5.   Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody
  2. Lee, Myungeun; Lu, Zhi Hong; Shoemaker, Charles B.; Tremblay, Jacqueline M.; St Croix,Brad; Seaman,Steven; Gonzalez-Pastor, Rebeca; Kashentseva, Elena A.; Dmitriev, Igor P.; Curiel, David T.
  3. Journal of Controlled Release : Official Journal of the Controlled Release Society. 2021, Jun 10; 334: 106-113.
  1. 6.   Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model
  2. Harrington, Brittney S; Ozaki, Michelle K; Caminear, Michael W; Hernandez, Lidia F; Jordan, Elizabeth; Kalinowski, Nicholas J; Goldlust, Ian S; Guha, Rajarshi; Ferrer, Marc; Thomas,Craig; Shetty,Jyoti; Tran,Bao; Wong,Nathan; House, Carrie D; Annunziata, Christina M
  3. Cancers. 2020, Jun 21; 12(6): pii: E1645.
  1. 7.   Inactivation of TRP53, PTEN, RB1 and/or CDH1 in the ovarian surface epithelium induces ovarian cancer transformation and metastasis
  2. Shi, Mingxin; Whorton, Allison E; Sekulovski, Nikola; Paquet, Marilène; MacLean, James A; Song, Yurong; Van Dyke, Terry; Hayashi, Kanako
  3. Biology of reproduction. 2020, MAY; 102(5): 1055-1064.
  1. 8.   Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment
  2. Maniati, Eleni; Berlato, Chiara; Gopinathan, Ganga; Heath, Owen; Kotantaki, Panoraia; Lakhani, Anissa; McDermott, Jacqueline; Pegrum, Colin; Delaine-Smith, Robin M; Pearce, Oliver M T; Hirani, Priyanka; Joy, Joash D; Szabova,Ludmila; Perets, Ruth; Sansom, Owen J; Drapkin, Ronny; Bailey, Peter; Balkwill, Frances R
  3. Cell reports. 2020, Jan 14; 30(2): 525-540.e7.
  1. 9.   Circulating estrogens and postmenopausal ovarian and endometrial cancer risk among current hormone users in the Women's Health Initiative Observational Study
  2. Trabert, Britton; Coburn, Sally B; Falk, Roni T; Manson, JoAnn E; Brinton, Louise A; Gass, Margery L; Kuller, Lewis H; Rohan, Thomas E; Pfeiffer, Ruth M; Qi, Lihong; Stefanick, Marcia L; Wentzensen, Nicolas; Anderson, Garnet L; Xu,Xia
  3. Cancer causes & control : CCC. 2019, Nov; 30(11): 1201-1211.
  1. 10.   Circulating androgens and postmenopausal ovarian cancer risk in the Women's Health Initiative Observational Study
  2. Trabert, Britton; Michels, Kara A; Anderson, Garnet L; Brinton, Louise A; Falk, Roni T; Geczik, Ashley M; Harris, Holly R; Pan, Kathy; Pfeiffer, Ruth M; Qi, Lihong; Rohan, Thomas; Wentzensen, Nicolas; Xu,Xia
  3. International journal of cancer. 2019, Oct 15; 145(8): 2051-2060.
  1. 11.   Conventional and Chemically Programmed Asymmetric Bispecific Antibodies Targeting Folate Receptor 1
  2. Qi, Junpeng; Hymel, David; Nelson, Christopher G.; Burke,Terrence; Rade, Christoph
  3. Frontiers in immunology. 2019, Aug 21; 10
  1. 12.   A phase I study of the PD-L1 inhibitor, durvalumab, in combination with a PARP inhibitor, olaparib, and a VEGFR1-3 inhibitor, cediranib, in recurrent women's cancers with biomarker analyses
  2. Zimmer, Alexandra S; Nichols,Erin; Cimino-Mathews, Ashley; Peer, Cody; Cao, Liang; Lee, Min-Jung; Kohn, Elise C; Annunziata, Christina M; Lipkowitz, Stanley; Trepel, Jane B; Sharma, Rajni; Mikkilineni, Lekha; Gatti-Mays, Margaret; Figg, William D; Houston, Nicole D; Lee, Jung-Min
  3. Journal for immunotherapy of cancer. 2019, Jul 25; 7(1): 197.
  1. 13.   Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target
  2. Brooks, Danielle; Zimmer, Alexandra; Wakefield, Lalage; Lyle, L Tiffany; Difilippantonio, Simone; Tucci, Fabio C; Illiano, Stephane; Annunziata, Christina M; Steeg, Patricia S
  3. Oncotarget. 2018, May 04; 9(34): 23462-23481.
  1. 14.   Novel primary amine diazeniumdiolates-Chemical and biological characterization
  2. Puglisi, Melany P; Bradaric, Michael J; Pontikis, John; Cabai, Jonathan; Weyna, Theodore; Tednes, Patrick; Schretzman, Robert; Rickert, Karl; Cao, Zhao; Andrei, Daniela
  3. Drug development research. 2018, May 02;
  1. 15.   Decoding NADPH oxidase 4 expression in human tumors
  2. Meitzler, Jennifer L; Makhlouf, Hala R; Antony, Smitha; Wu, Yongzhong; Butcher, Donna; Jiang, Guojian; Juhasz, Agnes; Lu, Jiamo; Dahan, Iris; Jansen-Dürr, Pidder; Pircher, Haymo; Shah, Ajay M; Roy, Krishnendu; Doroshow, James H
  3. Redox Biology. 2017, Oct; 13: 182-195.
  1. 16.   Dysregulation of mitotic machinery genes precedes genome instability during spontaneous pre-malignant transformation of mouse ovarian surface epithelial cells
  2. Urzua, U.; Ampuero, S.; Roby, K. F.; Owens, G. A.; Munroe, D. J.
  3. Bmc Genomics. 2016, 25-Oct; 17(Suppl 8): 728.
  1. 17.   Secretion of annexin A3 from ovarian cancer cells and its association with platinum resistance in ovarian cancer patients
  2. Yin, J.; Yan, X. D.; Yao, X.; Zhang, Y. L.; Shan, Y.; Mao, N.; Yang, Y. L.; Pan, L. Y.
  3. Journal of Cellular and Molecular Medicine. 2012, Feb; 16(2): 337-348.
  1. 18.   A novel high-affinity human monoclonal antibody to mesothelin
  2. Ho, M.; Feng, M. Q.; Fisher, R. J.; Rader, C.; Pastan, I.
  3. International Journal of Cancer. 2011, May; 128(9): 2020-2030.
  1. 19.   A Phase I study of paclitaxel and continuous daily CAI in patients with refractory solid tumors
  2. Azad, N.; Perroy, A.; Gardner, E.; Imamura, C. K.; Graves, C.; Sarosy, G. A.; Minasian, L.; Kotz, H.; Raggio, M.; Figg, W. D.; Kohn, E. C.
  3. Cancer Biology & Therapy. 2009 8(19): 1800-1805.
  1. 20.   BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers
  2. Yuli, C.; Shao, N.; Rao, R.; Aysola, P.; Reddy, V.; Oprea-llies, G.; Lee, L.; Okoli, J.; Partridge, E.; Reddy, E. S. P.; Rao, V. N.
  3. Oncogene. 2007, Sep; 26(41): 6031-6037.
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