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  1. 1.   A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity
  2. Makhaik, Sparsh; Rut, Wioletta; Choudhary, Shruti; Upadhyay, Tulsi; Hao, Chenzhou; Westberg, Michael; Bobst, Cedric; Yoo,Euna; Fejzo, Jasna; Lin, Michael Z; Bogyo, Matthew; Thompson, Paul; Drag, Marcin; Hardy, Jeanne A
  3. Protein Science : a publication of the Protein Society. 2025, Mar; 34(3): e70069.
  1. 2.   Improvements in large-scale production of Tobacco Etch Virus protease
  2. Messing,Simon; Barnhart,Kirsten; Drew,Matt; Granato-Guerrero,Natalie; Grose,Carissa; Higgins,Brianna; Hong,Min; Hull,Jenna; Perkins,Shelley; Poon,Ivy; Ramakrishnan,Nitya; Seabolt,Amanda; Taylor,Troy; Wall,Vanessa; Wright,Nick; Gillette,Bill; Esposito,Dom
  3. Protein Expression and Purification. 2024, Dec 14; 106648.
  1. 3.   Structural and virologic mechanism of the emergence of resistance to Mpro inhibitors in SARS-CoV-2
  2. Hattori, Shin-Ichiro; Bulut, Haydar; Hayashi, Hironori; Kishimoto, Naoki; Takamune, Nobutoki; Hasegawa, Kazuya; Furusawa, Yuri; Yamayoshi, Seiya; Murayama, Kazutaka; Tamamura, Hirokazu; Li,Mi; Wlodawer, Alexander; Kawaoka, Yoshihiro; Misumi, Shogo; Mitsuya, Hiroaki
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Sep 10; 121(37): e2404175121.
  1. 4.   Producing recombinant proteins in Vibrio natriegens
  2. Smith,Matthew; Hernández, José Sánchez; Messing,Simon; Ramakrishnan,Nitya; Higgins,Brianna; Mehalko,Jennifer; Perkins,Shelley; Wall,Vanessa; Grose,Carissa; Frank,Peter; Cregger, Julia; Le,Vi; Johnson,Adam; Sherekar, Mukul; Pagonis,Morgan; Drew,Matt; Hong,Min; Widmeyer, Stephanie R T; Denson,John-Paul; Snead,Kelly; Poon,Ivy; Waybright,Tim; Champagne, Allison; Esposito,Dom; Jones,Jane; Taylor,Troy; Gillette,Bill
  3. Microbial Cell Factories. 2024, Jul 24; 23(1): 208.
  1. 5.   P1' specificity of the S219V/R203G mutant tobacco etch virus protease
  2. Golda, Mária; Hoffka, Gyula; Cherry,Scott; Tropea, Joseph E; Lountos,George; Waugh, David S; Wlodawer,Alexander; Tozsér, József; Mótyán, János András
  3. Proteins. 2024, Apr 26;
  1. 6.   Unexpected tobacco etch virus (TEV) protease cleavage of recombinant human proteins
  2. Beaumont,Lauren; Mehalko,Jennifer; Johnson,Adam; Wall,Vanessa; Esposito,Dom
  3. Protein Expression and Purification. 2024, Apr 26; 220: 106488.
  1. 7.   Inhibition of Plasmodium falciparum plasmepsins by drugs targeting HIV-1 protease: A way forward for antimalarial drug discovery
  2. Mishra, Vandana; Deshmukh, Anuradha; Rathore, Ishan; Chakraborty, Satadru; Patankar, Swati; Gustchina,Alla; Wlodawer,Alexander; Yada, Rickey Y; Bhaumik, Prasenjit
  3. Current Research in Structural Biology. 2024, Jan 17; 7: 100128.
  1. 8.   Recent Advances in the Development of Non-Invasive Imaging Probes for Cancer Immunotherapy
  2. Kazim,Muhammad; Yoo,Euna
  3. Angewandte Chemie (International ed. in English). 2023, Oct 16; e202310694.
  1. 9.   Differential sensitivity of the yeast Lon protease Pim1p to impaired mitochondrial respiration
  2. Metzger,Meredith; Scales, Jessica L; Grant, Garis A; Molnar,Abby; Loncarek,Jadranka; Weissman,Allan
  3. The Journal of Biological Chemistry. 2023, Aug; 299(8): 104937.
  1. 10.   SARS-CoV-2 polyprotein substrate regulates the stepwise Mpro cleavage reaction
  2. Narwal, Manju; Armache, Jean-Paul; Edwards,Thomas; Murakami, Katsuhiko S
  3. The Journal of Biological Chemistry. 2023, Apr 10; 299(5): 104697.
  1. 11.   Self-inhibited state of Venezuelan equine encephalitis virus (VEEV) nsP2 cysteine protease: a crystallographic and molecular dynamics analysis
  2. Hoffka, Gyula; Lountos,George; Needle,Danielle; Wlodawer,Alexander; Waugh, David S; Tozsér, József; András Mótyán, János
  3. Journal of Molecular Biology. 2023, Feb 13; 435(6): 168012.
  1. 12.   Computational investigation of natural compounds as potential main protease (Mpro) inhibitors for SARS-CoV-2 virus
  2. Patel,Chiragkumar; Jani, Siddhi P; Prasanth Kumar, Sivakumar; Modi, Krunal M; Kumar, Yogesh
  3. Computers in Biology and Medicine. 2022, Nov 18; 151(Pt A): 106318.
  1. 13.   Unique Structural Fold of LonBA Protease from Bacillus subtilis, a Member of a Newly Identified Subfamily of Lon Proteases
  2. Gustchina,Alla; Li,Mi; Andrianova, Anna G; Kudzhaev, Arsen M; Lountos,George; Sekula, Bartosz; Cherry,Scott; Tropea, Joseph E; Smirnov, Ivan V; Wlodawer,Alexander; Rotanova, Tatyana V
  3. International Journal of Molecular Sciences. 2022, Sep 28; 23(19):
  1. 14.   Scaffolding viral protein NC nucleates phase separation of the HIV-1 biomolecular condensate
  2. Monette, Anne; Niu, Meijuan; Nijhoff Asser, Maya; Gorelick,Robert; Mouland, Andrew J
  3. Cell Reports. 2022, Aug 23; 40(8): 111251.
  1. 15.   The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease during Maturation
  2. Lyonnais, Sébastien; Sadiq, S Kashif; Lorca-Oró, Cristina; Dufau, Laure; Nieto-Marquez, Sara; Escribà, Tuixent; Gabrielli, Natalia; Tan, Xiao; Ouizougun-Oubari, Mohamed; Okoronkwo, Josephine; Reboud-Ravaux, Michèle; Gatell, José Maria; Marquet, Roland; Paillart, Jean-Christophe; Meyerhans, Andreas; Tisné, Carine; Gorelick,Robert; Mirambeau, Gilles
  3. Viruses. 2021, Nov 19; 13(11):
  1. 16.   Differential expression of Triggering Receptor Expressed on Myeloid cells 2 (Trem2) in tissue eosinophils
  2. Sek, Albert C.; Percopo, Caroline M.; Boddapati, Arun K.; Ma, Michelle; Geslewitz, Wendy E.; Krumholz, Julia O.; Lack,Justin; Rosenberg, Helene F.
  3. Journal of leukocyte biology. 2021, Oct; 110(4): 679-691.
  1. 17.   Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
  2. Li,Mi; Srp, Jaroslav; Mares, Michael; Wlodawer,Alexander; Gustchina,Alla
  3. Acta crystallographica. Section D, Structural biology. 2021, Aug 1; 77(Pt 8): 1084-1098.
  1. 18.   Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)
  2. Harrison, Jerry Joe E K; Tuske, Steve; Das, Kalyan; Ruiz, Francesc X; Bauman, Joseph D; Boyer,Paul; DeStefano, Jeffrey J; Hughes,Stephen; Arnold, Eddy
  3. Viruses. 2021, Aug; 13(8):
  1. 19.   Specificity of the HIV-1 Protease on Substrates Representing the Cleavage Site in the Proximal Zinc-Finger of HIV-1 Nucleocapsid Protein
  2. Motyan, Janos Andras; Miczi, Mario; Oroszlan, Stephen; Tozser, Jozsef
  3. Viruses. 2021, Jun; 13(6):
  1. 20.   Crystallographic models of SARS-CoV-2 3CL(pro): in-death assessment of structure quality and validation
  2. Jaskolski, Mariusz; Dauter, Zbigniew; Shabalin, Ivan G.; Gilski, Miroslaw; Brzezinski, Dariusz; Kowiel, Marcin; Rupp, Bernhard; Wlodawer,Alexander
  3. IUCrJ. 2021, Feb 9; 8(Pt 2): 238-256.
  1. 21.   Development of a Cell-Based Luciferase Complementation Assay for Identification of SARS-CoV-2 3CL(pro) Inhibitors
  2. Rawson, Jonathan M. O.; Duchon, Alice; Nikolaitchik, Olga A.; Pathak, Vinay K.; Hu, Wei-Shau
  3. Viruses. 2021, Jan 24; 13(2):
  1. 22.   The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms
  2. Beyer, Hannes M; Virtanen, Salla I; Aranko, A Sesilja; Mikula, Kornelia M; Lountos,George; Wlodawer,Alexander; Ollila, O H Samuli; Iwaï, Hideo
  3. International journal of molecular sciences. 2020, Nov 07; 21(21): 8367.
  1. 23.   Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes
  2. Zhou, Tongqing; Teng, I-Ting; Olia, Adam S; Cerutti, Gabriele; Gorman, Jason; Nazzari, Alexandra; Shi, Wei; Tsybovsky,Yaroslav; Wang, Lingshu; Wang, Shuishu; Zhang, Baoshan; Zhang, Yi; Katsamba, Phinikoula S; Petrova, Yuliya; Banach, Bailey B; Fahad, Ahmed S; Liu, Lihong; Lopez Acevedo, Sheila N; Madan, Bharat; Oliveira de Souza, Matheus; Pan, Xiaoli; Wang, Pengfei; Wolfe, Jacy R; Yin, Michael; Ho, David D; Phung, Emily; DiPiazza, Anthony; Chang, Lauren A; Abiona, Olubukola M; Corbett, Kizzmekia S; DeKosky, Brandon J; Graham, Barney S; Mascola, John R; Misasi, John; Ruckwardt, Tracy; Sullivan, Nancy J; Shapiro, Lawrence; Kwong, Peter D
  3. Cell reports. 2020, Oct 27; 33(4): 108322.
  1. 24.   Specificity Studies of the Venezuelan Equine Encephalitis Virus Non-Structural Protein 2 Protease Using Recombinant Fluorescent Substrates
  2. Bozóki, Beáta; Mótyán, János András; Hoffka, Gyula; Waugh,David; Tozsér, József
  3. International journal of molecular sciences. 2020, Oct 16; 21(20): pii: E7686.
  1. 25.   Ligand-centered assessment of SARS-CoV-2 drug target models in the Protein Data Bank
  2. Wlodawer,Alexander; Dauter,Zbigniew; Shabalin, Ivan; Gilski, Miroslaw; Brzezinski, Dariusz; Kowiel, Marcin; Minor, Wladek; Rupp, Bernhard; Jaskolski, Mariusz
  3. The FEBS journal. 2020, JUN 24;
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