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  1. 1.   SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
  2. Ohara, Yuuki; Tang, Wei; Liu, Huaitian; Yang, Shouhui; Dorsey, Tiffany H; Cawley, Helen; Moreno, Paloma; Chari,Raj; Guest,Mary; Azizian, Azadeh; Gaedcke, Jochen; Ghadimi, Michael; Hanna, Nader; Ambs, Stefan; Hussain, S Perwez
  3. Cell Reports. 2023, Nov 18; 42(12): 113434.
  1. 2.   RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation
  2. Smith,Russell; Terrell,Elizabeth; Insinna, Christine; Agamasu, Constance; Wagner, Morgan E; Ritt,Daniel; Stauffer,Jimmy; Stephen,Andy; Morrison,Deborah
  3. Molecular Cell. 2022, Nov 17; 82(22): 4262-4276.
  1. 3.   Unique Structural Fold of LonBA Protease from Bacillus subtilis, a Member of a Newly Identified Subfamily of Lon Proteases
  2. Gustchina,Alla; Li,Mi; Andrianova, Anna G; Kudzhaev, Arsen M; Lountos,George; Sekula, Bartosz; Cherry,Scott; Tropea, Joseph E; Smirnov, Ivan V; Wlodawer,Alexander; Rotanova, Tatyana V
  3. International Journal of Molecular Sciences. 2022, Sep 28; 23(19):
  1. 4.   The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1
  2. Sanchez-Solana, Beatriz; Wang, Dunrui; Qian, Xiaolan; Velayoudame, Parthibane; Simanshu,Dhirendra; Acharya,Jairaj; Lowy, Douglas R
  3. Molecular Cancer. 2021, Nov 02; 20(1):
  1. 5.   SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis
  2. Velayoudame,Parthibane; Lin, Jing; Acharya, Diwash; Abimannan,Thiruvaimozhi; Srideshikan, Sargur Madabushi; Klarmann,Kim; Yang,Acong; Soheilian,Ferri; Nagashima,Kunio; Fox,Stephen; Andresson,Thorkell; Tessarollo,Lino; Keller,Jonathan; Acharya,Usha; Acharya,Jairaj
  3. The Journal of biological chemistry. 2021, Mar 01; 296
  1. 6.   The KRAS and other prenylated polybasic domain membrane anchors recognize phosphatidylserine acyl chain structure
  2. Zhou, Yong; Prakash, Priyanka S.; Liang, Hong; Gorfe, Alemayehu A.; Hancock, John F.
  3. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021, Feb 9; 118(6):
  1. 7.   Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma
  2. Lin, Bonan; Zhou, Xiaomeng; Lin, Shuye; Wang, Xiaoyue; Zhang, Meiying; Cao, Baoping; Dong, Yan; Yang, Shuai; Wang, Jiming; Guo, Mingzhou; Huang, Jiaqiang
  3. Journal of Molecular Medicine (Berlin, Germany). 2017, Nov; 95(11): 1237-1249.
  1. 8.   The Enolization Chemistry of a Thioester-Dependent Racemase: The 1.4 angstrom Crystal Structure of a Reaction Intermediate Complex Characterized by Detailed QM/MM Calculations
  2. Sharma, S.; Bhaumik, P.; Schmitz, W.; Venkatesan, R.; Hiltunen, J. K.; Conzelmann, E.; Juffer, A. H.; Wierenga, R. K.
  3. Journal of Physical Chemistry B. 2012, Mar; 116(11): 3619-3629.
  1. 9.   One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent
  2. Romagnoli, R.; Baraldi, P. G.; Cara, C. L.; Salvador, M. K.; Bortolozzi, R.; Basso, G.; Viola, G.; Balzarini, J.; Brancale, A.; Fu, X. H.; Li, J.; Zhang, S. Z.; Hamel, E.
  3. European Journal of Medicinal Chemistry. 2011, Dec; 46(12): 6015-6024.
  1. 10.   Optimization of a Cyclic Peptide Inhibitor of Ser/Thr Phosphatase PPM1D (Wip1)
  2. Hayashi, R.; Tanoue, K.; Durell, S. R.; Chatterjee, D. K.; Jenkins, L. M. M.; Appella, D. H.; Appella, E.
  3. Biochemistry. 2011, May; 50(21): 4537-4549.
  1. 11.   Synthesis and in vitro Evaluation of 3H-Pyrrolo[3,2-f]quinolin-9-one Derivatives That Show Potent and Selective Anti-leukemic Activity
  2. Ferlin, M. G.; Bortolozzi, R.; Brun, P.; Castagliuolo, I.; Hamel, E.; Basso, G.; Viola, G.
  3. Chemmedchem. 2010, Jul; 5(8): 1373-1385.
  1. 12.   Polo-box domain: a versatile mediator of polo-like kinase function
  2. Park, J. E.; Soung, N. K.; Johmura, Y.; Kang, Y. H.; Liao, C.; Lee, K. H.; Park, C. H.; Nicklaus, M. C.; Lee, K. S.
  3. Cellular and Molecular Life Sciences. 2010, Jun; 67(12): 1957-1970.
  1. 13.   Matriptase/epithin participates in mammary epithelial cell growth and morphogenesis through HGF activation
  2. Lee, S. L.; Huang, P. Y.; Roller, P.; Cho, E. G.; Park, D.; Dickson, R. B.
  3. Mechanisms of Development. 2010, Jan-Feb; 127(1-2): 82-95.
  1. 14.   KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals
  2. Dougherty, M. K.; Ritt, D. A.; Zhou, M.; Specht, S. I.; Monson, D. M.; Veenstra, T. D.; Morrison, D. K.
  3. Molecular Cell. 2009, Jun 26; 34(6): 652-62.
  1. 15.   Structure-activity relationship studies for the peptide portion of the bladder epithelial cell antiproliferative factor from interstitial cystitis patients
  2. Kaczmarek, P.; Keay, S. K.; Tocci, G. M.; Koch, K. R.; Zhang, C. O.; Barchi, J. J.; Grkovic, D.; Guo, L.; Michejda, C. J.
  3. Journal of Medicinal Chemistry. 2008 51(19): 5974-5983.
  1. 16.   A mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type IIFN-induced apoptosis
  2. Scarzello, A. J.; Romero-Weaver, A. L.; Maher, S. G.; Veenstra, T. D.; Zhou, M.; Qin, A.; Donnelly, R. P.; Sheikh, F.; Gamero, A. M.
  3. Molecular Biology of the Cell. 2007, Jul; 18(7): 2455-2462.
  1. 17.   A comparative study of the expression of serine proteinases in quiescent seeds and in developing Canavalia ensiformis plants
  2. Demartini, D. R.; Wlodawer, A.; Carlini, C. R.
  3. Journal of Experimental Botany. 2007, Feb; 58(3): 521-532.
  1. 18.   Design and synthesis of redox stable analogues of sunflower trypsin inhibitors (SFTI-1) on solid support, potent inhibitors of matriptase
  2. Jiang, S.; Li, P.; Lee, S. L.; Lin, C. Y.; Long, Y. Q.; Johnson, M. D.; Dickson, R. B.; Roller, P. P.
  3. Organic Letters. 2007, Jan; 9(1): 9-12.
  1. 19.   CK2 is a component of the KSR1 scaffold complex that contributes to Raf kinase activation
  2. Ritt, D. A.; Zhou, M.; Conrads, T. P.; Veenstra, T. D.; Copeland, T. D.; Morrison, D. K.
  3. Current Biology. 2007, Jan; 17(2): 179-184.
  1. 20.   Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesis
  2. Timofeeva, O. A.; Plisov, S.; Evseev, A. A.; Peng, S.; Jose-Kampfner, M.; Lovvorn, H. N.; Dome, J. S.; Perantoni, A. O.
  3. Oncogene. 2006, Dec; 25(58): 7555-7564.
  1. 21.   Development of therapeutics for chronic HCV infection
  2. Huang, Z.; Murray, M. G.; Secrist, J. A.
  3. Antiviral Research. 2006, Sep; 71(2-3): 351-362.
  1. 22.   Processing, catalytic activity and crystal structures of kumamolisin-As with an engineered active site
  2. Okubo, A.; Li, M.; Ashida, M.; Oyama, H.; Gustchina, A.; Oda, K.; Dunn, B. M.; Wlodawer, A.; Nakayama, T.
  3. Febs Journal. 2006, Jun; 273(11): 2563-2576.
  1. 23.   The importance of dynamics in substrate-assisted catalysis and specificity
  2. Xu, Q.; Guo, H.; Wlodawer, A.; Guo, H.
  3. Journal of the American Chemical Society. 2006, MAY 10; 128(18): 5994-5995.
  1. 24.   Nitric oxide regulates prolidase activity by serine/threonine phosphorylation
  2. Surazynski, A.; Liu, Y. M.; Miltyk, W.; Phang, J. M.
  3. Journal of Cellular Biochemistry. 2005, DEC 1; 96(5): 1086-1094.
  1. 25.   Suppression of p65 phosphorylation coincides with inhibition of I kappa B alpha polyubiquitination and degradation
  2. Hu, J.; Haseebuddin, M.; Young, M.; Colburn, N. H.
  3. Molecular Carcinogenesis. 2005, DEC; 44(4): 274-284.
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