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  1. 1.   Robust regulation of transcription pausing in Escherichia coli by the ubiquitous elongation factor NusG
  2. Yakhnin,Alex; Bubunenko,Mikhail; Mandell, Zachary F; Lubkowska,Lucyna; Husher, Sara; Babitzke, Paul; Kashlev,Mikhail
  3. Proceedings of the National Academy of Sciences of the United States of America. 2023, Jun 13; 120(24): e2221114120.
  1. 2.   High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma
  2. Lang, Martin; Schmidt,Laura; Wilson, Kelli M; Ricketts, Christopher J; Sourbier, Carole; Vocke, Cathy D; Wei, Darmood; Crooks, Daniel R; Yang, Youfeng; Gibbs, Benjamin K; Zhang, Xiaohu; Klumpp-Thomas, Carleen; Chen, Lu; Guha, Rajarshi; Ferrer, Marc; McKnight, Crystal; Itkin, Zina; Wangsa, Darawalee; Wangsa, Danny; James,Amy; Difilippantonio,Simone; Karim, Baktir; Morís, Francisco; Ried, Thomas; Merino, Maria J; Srinivasan, Ramaprasad; Thomas, Craig J; Linehan, W Marston
  3. Journal of Experimental & Clinical Cancer Research : CR. 2023, Apr 25; 42(1): 99.
  1. 3.   The structural basis of BCR-ABL recruitment of GRB2 in chronic myelogenous leukemia
  2. Liu,Yonglan; Jang,Hyunbum; Zhang,Mingzhen; Tsai,Chung-Jung; Maloney,Ryan; Nussinov,Ruth
  3. Biophysical Journal. 2022, May 31;
  1. 4.   Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate
  2. Funasaki, Shintaro; Mehanna, Sally; Ma, Wenjuan; Nishizawa, Hidekazu; Kamikubo, Yasuhiko; Sugiyama, Hiroshi; Ikeda, Shuji; Motoshima, Takanobu; Hasumi, Hisashi; Linehan, W Marston; Schmidt,Laura; Ricketts, Chris; Suda, Toshio; Oike, Yuichi; Kamba, Tomomi; Baba, Masaya
  3. Cancer Science. 2022, Apr 09;
  1. 5.   Cytoplasmic-translocated Ku70 senses intracellular DNA and mediates interferon-lambda1 induction
  2. Sui,Hongyan; Chen,Qian; Imamichi,Tomozumi
  3. Immunology. 2021, Jul; 163(3): 323-337.
  1. 6.   Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection
  2. Singh, Kasha P; Zerbato, Jennifer M; Zhao, Wei; Braat, Sabine; Deleage,Claire; Tennakoon, G Surekha; Mason, Hugh; Dantanarayana, Ashanti; Rhodes, Ajantha; Rhodes, Jake W; Torresi, Joe; Harman, Andrew N; Revill, Peter A; Crane, Megan; Estes, Jacob D; Avihingsanon, Anchalee; Lewin, Sharon R; Audsley, Jennifer
  3. PLoS pathogens. 2020, Sep 08; 16(9): e1008744.
  1. 7.   NusG controls transcription pausing and RNA polymerase translocation throughout the Bacillus subtilis genome
  2. Yakhnin, Alexander V; FitzGerald, Peter C; McIntosh, Carl; Yakhnin, Helen; Kireeva, Maria; Turek-Herman, Joshua; Mandell, Zachary F; Kashlev,Mikhail; Babitzke, Paul
  3. Proceedings of the National Academy of Sciences of the United States of America. 2020, SEP 1; 117(35): 21628-21636.
  1. 8.   Helminth Mediated Attenuation of Systemic Inflammation and Microbial Translocation in Helminth-Diabetes Comorbidity
  2. Rajamanickam, Anuradha; Munisankar, Saravanan; Menon, Pradeep A.; Dolla, Chandrakumar; Nutman, Thomas B.; Babu, Subash
  3. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2020, AUG 31; 10: 431.
  1. 9.   Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins
  2. Tranter, Dale; Paatero, Anja O.; Kawaguchi, Shinsaku; Kazemi, Soheila; Serrill, Jeffrey D.; Kellosalo, Juho; Vogel, Walter K.; Richter, Uwe; Mattos, Daphne R.; Wan, Xuemei; Thornburg,Chris; Oishi, Shinya; McPhail, Kerry L.; Ishmael, Jane E.; Paavilainen, Ville O.
  3. ACS CHEMICAL BIOLOGY. 2020, AUG 21; 15(8): 2125-2136.
  1. 10.   Blood RNA Integrity is a Direct and Simple Reporter of Radiation Exposure and Prognosis: A Pilot Study
  2. Alkhalil, Abdulnaser; Clifford, John L; Ball, Robert; Day, Anna; Chan, Rossana; Carney, Bonnie C; Miller, Stacy Ann; Campbell, Ross; Kumar, Raina; Gautam, Aarti; Hammamieh, Rasha; Moffatt, Lauren T; Shupp, Jeffrey W
  3. Radiation research. 2020, JUN; 193(6): 543-551.
  1. 11.   HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases
  2. Vujkovic-Cvijin, I; Sortino,Ornella; Verheij, E; Sklar, J; Wit, F W; Kootstra, N A; Sellers, B; Brenchley, J M; Ananworanich, J; Loeff, M Schim van der; Belkaid, Y; Reiss, P; Sereti, I
  3. Nature communications. 2020, May 15; 11(1): 2448.
  1. 12.   African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity
  2. Raehtz, Kevin D.; Barrenas, Fredrik; Xu, Cuiling; Busman-Sahay, Kathleen; Valentine, Audrey; Law, Lynn; Ma, Dongzhu; Policicchio, Benjamin B.; Wijewardana, Viskam; Brocca-Cofano, Egidio; Trichel, Anita; Gale, Michael; Keele,Brandon; Estes, Jacob D.; Apetrei, Cristian; Pandrea, Ivona
  3. PLOS PATHOGENS. 2020, MAR; 16(3):
  1. 13.   Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma
  2. Clark, David J; Dhanasekaran, Saravana M; Petralia, Francesca; Pan, Jianbo; Song, Xiaoyu; Hu, Yingwei; da Veiga Leprevost, Felipe; Reva, Boris; Lih, Tung-Shing M; Chang, Hui-Yin; Ma, Weiping; Huang, Chen; Ricketts, Christopher J; Chen, Lijun; Krek, Azra; Li, Yize; Rykunov, Dmitry; Li, Qing Kay; Chen, Lin S; Ozbek, Umut; Vasaikar, Suhas; Wu, Yige; Yoo, Seungyeul; Chowdhury, Shrabanti; Wyczalkowski, Matthew A; Ji, Jiayi; Schnaubelt, Michael; Kong, Andy; Sethuraman, Sunantha; Avtonomov, Dmitry M; Ao, Minghui; Colaprico, Antonio; Cao, Song; Cho, Kyung-Cho; Kalayci, Selim; Ma, Shiyong; Liu, Wenke; Ruggles, Kelly; Calinawan, Anna; Gümüs, Zeynep H; Geizler, Daniel; Kawaler, Emily; Teo, Guo Ci; Wen, Bo; Zhang, Yuping; Keegan, Sarah; Li, Kai; Chen, Feng; Edwards, Nathan; Pierorazio, Phillip M; Chen, Xi Steven; Pavlovich, Christian P; Hakimi, A Ari; Brominski, Gabriel; Hsieh, James J; Antczak, Andrzej; Omelchenko, Tatiana; Lubinski, Jan; Wiznerowicz, Maciej; Linehan, W Marston; Kinsinger, Christopher R; Thiagarajan,Mathangi; Boja, Emily S; Mesri, Mehdi; Hiltke, Tara; Robles, Ana I; Rodriguez, Henry; Qian, Jiang; Fenyö, David; Zhang, Bing; Ding, Li; Schadt, Eric; Chinnaiyan, Arul M; Zhang, Zhen; Omenn, Gilbert S; Cieslik, Marcin; Chan, Daniel W; Nesvizhskii, Alexey I; Wang, Pei; Zhang, Hui
  3. Cell. 2019, Oct 31; 179(4): 964-983.e31.
  1. 14.   Targeting glycolysis through inhibition of lactate dehydrogenase impairs tumor growth in preclinical models of Ewing sarcoma
  2. Yeung, Choh; Gibson, Anna E; Issaq, Sameer H; Oshima, Nobu; Baumgart, Joshua T; Edessa, Leah D; Rai, Ganesha; Urban, Daniel J; Johnson, Michelle S; Benavides, Gloria A; Squadrito, Giuseppe L; Yohe, Marielle E; Lei, Haiyan; Eldridge, Sandy; Hamre,John; Dowdy, Tyrone; Ruiz-Rodado, Victor; Lita, Adrian; Mendoza, Arnulfo; Shern, Jack F; Larion, Mioara; Helman, Lee J; Stott,Gordon; Krishna, Murali C; Hall, Matthew D; Darley-Usmar, Victor; Neckers, Leonard M; Heske, Christine M
  3. Cancer research. 2019, OCT 1; 79(19): 5060-5073.
  1. 15.   Structures and operating principles of the replisome
  2. Gao, Yang; Cui, Yanxiang; Fox,Tara; Lin, Shiqiang; Wang, Huaibin; De Val Alda,Natalia; Zhou, Z. Hong; Yang, Wei
  3. Science (New York, N.Y.). 2019, Feb 22; 363: 835-+.
  1. 16.   Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation
  2. Preston, G Michael; Guerriero, Christopher J; Metzger, Meredith; Michaelis, Susan; Brodsky, Jeffrey L
  3. Molecular Cell. 2018, Apr 19; 70(2): 242-253.e6.
  1. 17.   PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability
  2. Gryder, Berkley E.; Yohe, Marielle E.; Chou, Hsien-Chao; Zhang, Xiaohu; Marques, Joana; Wachtel, Marco; Schaefer, Beat; Sen, Nirmalya; Song, Young; Gualtieri, Alberto; Pomella, Silvia; Rota, Rossella; Cleveland, Abigail; Wen, Xinyu; Sindiri, Sivasish; Wei, Jun S.; Barr, Frederic G.; Das, Sudipto; Andresson, Thorkell; Guha, Rajarshi; Lal-Nag, Madhu; Ferrer, Marc; Shern, Jack F.; Zhao, Keji; Thomas, Craig J.; Khan, Javed
  3. Cancer Discovery. 2017, Aug; 7(8): 884-899.
  1. 18.   Methoxychalcone inhibitors of androgen receptor translocation and function
  2. Kim, Y. S.; Kumar, V.; Lee, S.; Iwai, A.; Neckers, L.; Malhotra, S. V.; Trepel, J. B.
  3. Bioorganic & Medicinal Chemistry Letters. 2012, Mar; 22(5): 2105-2109.
  1. 19.   The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes
  2. Bintu, L.; Kopaczynska, M.; Hodges, C.; Lubkowska, L.; Kashlev, M.; Bustamante, C.
  3. Nature Structural & Molecular Biology. 2011, Dec; 18(12): 1394-U112.
  1. 20.   N-Methyl-Substituted Fluorescent DAG-Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity
  2. Gal, N.; Kolusheva, S.; Kedei, N.; Telek, A.; Naeem, T. A.; Lewin, N. E.; Lim, L.; Mannan, P.; Garfield, S. H.; El Kazzouli, S.; Sigano, D. M.; Marquez, V. E.; Blumberg, P. M.; Jelinek, R.
  3. Chembiochem. 2011, Oct; 12(15): 2331-2340.
  1. 21.   Interaction of RNA Polymerase II Fork Loop 2 with Downstream Non-template DNA Regulates Transcription Elongation
  2. Kireeva, M. L.; Domecq, C.; Coulombe, B.; Burton, Z. F.; Kashlev, M.
  3. Journal of Biological Chemistry. 2011, Sep; 286(35): 30898-30910.
  1. 22.   Differential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes
  2. Srinivasula, S.; Lempicki, R. A.; Adelsberger, J. W.; Huang, C. Y.; Roark, J.; Lee, P. I.; Rupert, A.; Stevens, R.; Sereti, I.; Lane, H. C.; Di Mascio, M.; Kovacs, J. A.
  3. Blood. 2011, Jul; 118(2): 262-270.
  1. 23.   Protein Kinase C zeta Mediates mu-Opioid Receptor-induced Cross-desensitization of Chemokine Receptor CCR5
  2. Song, C. C.; Rahim, R. T.; Davey, P. C.; Bednar, F.; Bardi, G.; Zhang, L.; Zhang, N.; Oppenheim, J. J.; Rogers, T. J.
  3. Journal of Biological Chemistry. 2011, Jun; 286(23): 20354-20365.
  1. 24.   Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery
  2. Kiris, E.; Nuss, J. E.; Burnett, J. C.; Kota, K. P.; Koh, D. C.; Wanner, L. M.; Torres-Melendez, E.; Gussio, R.; Tessarollo, L.; Bavari, S.
  3. Stem Cell Research. 2011, May; 6(3): 195-205.
  1. 25.   Ubiquitylation in ERAD: Reversing to Go Forward?
  2. Tsai, Y. C.; Weissman, A. M.
  3. Plos Biology. 2011, Mar; 9(3):
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