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  1. 1.   Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production
  2. Baseler, Walter; Davies, Luke; Quigley, L.; Ridnour, Lisa; Weiss, Jonathan; Hussain, S. P.; Wink, David; McVicar, Daniel
  3. Redox biology. 2016, Dec; 10: 12-23.
  1. 2.   Hypoxia, stem cells and bone tumor
  2. Zeng, W.; Wan, R.; Zheng, Y. H.; Singh, S. R.; Wei, Y. Y.
  3. Cancer Letters. 2011, Dec; 313(2): 129-136.
  1. 3.   Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1 alpha in Advanced Solid Tumors
  2. Kummar, S.; Raffeld, M.; Juwara, L.; Horneffer, Y.; Strassberger, A.; Allen, D.; Steinberg, S. M.; Rapisarda, A.; Spencer, S. D.; Figg, W. D.; Chen, X. H.; Turkbey, I. B.; Choyke, P.; Murgo, A. J.; Doroshow, J. H.; Melillo, G.
  3. Clinical Cancer Research. 2011, Aug; 17(15): 5123-5131.
  1. 4.   The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling
  2. Ping, Y. F.; Yao, X. H.; Jiang, J. Y.; Zhao, L. T.; Yu, S. C.; Jiang, T.; Lin, M. C. M.; Chen, J. H.; Wang, B.; Zhang, R.; Cui, Y. H.; Qian, C.; Wang, J. M.; Bian, X. W.
  3. Journal of Pathology. 2011, Jul; 224(3): 344-354.
  1. 5.   Importance of macrophage inflammatory protein-la and splenic macrophages in neurodegeneration induced by PVC-211 murine leukemia virus
  2. Li, X. J.; Zhang, X. A.; Cmarik, J. L.; Ruscetti, S.
  3. Virology. 2011, Jan; 409(2): 198-203.
  1. 6.   The tumour suppressor C/EBP delta inhibits FBXW7 expression and promotes mammary tumour metastasis
  2. Balamurugan, K.; Wang, J. M.; Tsai, H. H.; Sharan, S.; Anver, M.; Leighty, R.; Sterneck, E.
  3. Embo Journal. 2010, Dec; 29(24): 4106-4117.
  1. 7.   SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism
  2. Ponugoti, B.; Kim, D. H.; Xiao, Z.; Smith, Z.; Miao, J.; Zang, M. W.; Wu, S. Y.; Chiang, C. M.; Veenstra, T. D.; Kemper, J. K.
  3. Journal of Biological Chemistry. 2010, Oct; 285(44): 33959-33970.
  1. 8.   Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1 alpha Expression in an AhR-Independent Fashion
  2. Terzuoli, E.; Puppo, M.; Rapisarda, A.; Uranchimeg, B.; Cao, L. A.; Burger, A. M.; Ziche, M.; Melillo, G.
  3. Cancer Research. 2010, Sep 1; 70(17): 6837-6848.
  1. 9.   Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion
  2. Santhanam, A. N.; Baker, A. R.; Hegamyer, G.; Kirschmann, D. A.; Colburn, N. H.
  3. Oncogene. 2010, Jul; 29(27): 3921-3932.
  1. 10.   Antiangiogenic agents and HIF-1 inhibitors meet at the crossroads
  2. Rapisarda, A.; Shoemaker, R. H.; Melillo, G.
  3. Cell Cycle. 2009, Dec; 8(24): 4040-4043.
  1. 11.   FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States
  2. Kemper, J. K.; Xiao, Z.; Ponugoti, B.; Miao, J.; Fang, S.; Kanamaluru, D.; Tsang, S.; Wu, S. Y.; Chiang, C. M.; Veenstra, T. D.
  3. Cell Metabolism. 2009 10(5): 392-404.
  1. 12.   Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition
  2. Rapisarda, A.; Hollingshead, M.; Uranchimeg, B.; Bonomi, C. A.; Borgel, S. D.; Carter, J. P.; Gehrs, B.; Raffeld, M.; Kinders, R. J.; Parchment, R.; Anver, M. R.; Shoemaker, R. H.; Melillo, G.
  3. Molecular Cancer Therapeutics. 2009 8(7): 1867-1877.
  1. 13.   Endothelial monocyte activating polypeptide-II modulates endothelial cell responses by degrading hypoxia-inducible factor-1alpha through interaction with PSMA7, a component of the proteasome
  2. Tandle, A. T.; Calvani, M.; Uranchimeg, B.; Zahavi, D.; Melillo, G.; Libutti, S. K.
  3. Experimental Cell Research. 2009 315(11): 1850-1859.
  1. 14.   CCL3L1 and HIV/AIDS susceptibility
  2. Urban, T. J.; Weintrob, A. C.; Fellay, J.; Colombo, S.; Shianna, K. V.; Gumbs, C.; Rotger, M.; Pelak, K.; Dang, K. K.; Detels, R.; Martinson, J. J.; O'Brien, S. J.; Letvin, N. L.; McMichael, A. J.; Haynes, B. F.; Carrington, M.; Telenti, A.
  3. Nature Medicine. 2009 15(10): 1110-1112.
  1. 15.   Transcriptome of hypoxic immature dendritic cells: Modulation of chemokine/receptor expression
  2. Ricciardi, A.; Elia, A. R.; Cappello, P.; Puppo, M.; Vann, C.; Fardin, P.; Eva, A.; Munroe, D.; Wu, X. L.; Giovarelli, M.; Varesio, L.
  3. Molecular Cancer Research. 2008 6(2): 175-185.
  1. 16.   Expression of hypoxia-inducible factor 1 alpha, hypoxia-inducible factor 2 alpha, and von Hippel-Lindau protein in epitheLiaL ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1 alpha is an independent prognostic factor in ovarian carcinoma
  2. Osada, R.; Horiuchi, A.; Kikuchi, N.; Yoshida, J.; Hayashi, A.; Ota, M.; Katsuyama, Y.; Melilo, G.; Konishi, I.
  3. Human Pathology. 2007, Sep; 38(9): 1310-1320.
  1. 17.   Targeting hypoxia cell signaling for cancer therapy
  2. Melillo, G.
  3. Cancer and Metastasis Reviews. 2007, Jun; 26(2): 341-352.
  1. 18.   The role of ascorbate in the modulation of HIF-1 alpha protein and HIF-dependent transcription by chromium(VI) and nickel(II)
  2. Kaczmarek, M.; Timofeeva, O. A.; Karaczyn, A.; Malyguine, A.; Kasprzak, K. S.; Salnikow, K.
  3. Free Radical Biology and Medicine. 2007, Apr; 42(8): 1246-1257.
  1. 19.   Crinamine from Crinum asiaticum var.japonicum inhibits hypoxia inducible factor-1 activity but not activity of hypoxia inducible factor-2
  2. Kim, Y. H.; Park, E. J.; Park, M. H.; Badarch, U.; Woldemichael, G. M.; Beutler, J. A.
  3. Biological & Pharmaceutical Bulletin. 2006, Oct; 29(10): 2140-2142.
  1. 20.   Inflammatory processes triggered by TCR engagement or by local cytokine expression: differences in profiles of gene expression and infiltrating cell populations
  2. Takase, H.; Yu, C. R.; Ham, D. I.; Chan, C. C.; Chen, J.; Vistica, B. P.; Wawrousek, E. F.; Durum, S. K.; Egwuagu, C. E.; Gery, I.
  3. Journal of Leukocyte Biology. 2006, Sep; 80(3): 538-545.
  1. 21.   Inhibiting hypoxia-inducible factor 1 for cancer therapy
  2. Melillo, G.
  3. Molecular Cancer Research. 2006, Sep; 4(9): 601-605.
  1. 22.   Development of a cell-based reporter assay for screening of inhibitors of hypoxia-inducible factor 2-induced gene expression
  2. Woldemichael, G. M.; Vasselli, J. R.; Gardella, R. S.; McKee, T. C.; Linehan, W. M.; McMahon, J. B.
  3. Journal of Biomolecular Screening. 2006, Sep; 11(6): 678-687.
  1. 23.   Genetic variation in the CCL18-CCL3-CCL4 chemokine gene cluster influences HIV type 1 transmission and AIDS disease progression
  2. Modi, W. S.; Lautenberger, J.; An, P.; Scott, K.; Goedert, J. J.; Kirk, G. D.; Buchbinder, S.; Phair, J.; Donfield, S.; O'Brien, S. J.; Winkler, C.
  3. American Journal of Human Genetics. 2006, Jul; 79(1): 120-128.
  1. 24.   Meeting report: Exploiting the Tumor Microenvironment for Therapeutics
  2. Melillo, G.; Semenza, G. L.
  3. Cancer Research. 2006, MAY 1; 66(9): 4558-4560.
  1. 25.   Expression of hypoxia inducible factor-1 alpha and 2 alpha in genetically distinct early renal cortical tumors
  2. Kim, C. M.; Vocke, C.; Torres-Cabala, C.; Yang, Y. F.; Schmidt, L.; Walther, M.; Linehan, W. M.
  3. Journal of Urology. 2006, May; 175(5): 1908-1914.
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