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  1. 1.   Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKC delta
  2. Choi, Y.; Pu, Y.; Peach, M. L.; Kang, J. H.; Lewin, N. E.; Sigano, D. M.; Garfield, S. H.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2007, Jul; 50(15): 3465-3481.
  1. 2.   Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups
  2. Malolanarasimhan, K.; Kedei, N.; Sigano, D. M.; Kelley, J. A.; Lai, C. C.; Lewin, N. E.; Surawski, R. J.; Pavlyukovets, V. A.; Garfield, S. H.; Wincovitch, S.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2007, Mar; 50(5): 962-978.
  1. 3.   Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms
  2. Pu, Y. M.; Peach, M. L.; Garfield, S. H.; Wincovitch, S.; Marquez, V. E.; Blumberg, P. M.
  3. Journal of Biological Chemistry. 2006, Nov; 281(44): 33773-33788.
  1. 4.   Transplacental arsenic plus postnatal 12-O-teradecanoyl phorbol-13-acetate exposures associated with hepatocarcinogenesis induce similar aberrant gene expression patterns in male and female mouse liver
  2. Liu, J.; Xie, Y. X.; Merrick, B. A.; Shen, J.; Ducharme, D. M. K.; Collins, J.; Diwan, B. A.; Logsdon, D.; Waalkes, M. P.
  3. Toxicology and Applied Pharmacology. 2006, Jun; 213(3): 216-223.
  1. 5.   p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase
  2. Zhao, Y. F.; Chaiswing, L.; Velez, J. M.; Batinic-Haberle, I.; Colburn, N. H.; Oberley, T. D.; St Clair, D. K.
  3. Cancer Research. 2005, MAY 1; 65(9): 3745-3750.
  1. 6.   Protein kinase C alpha-mediated chemotaxis of neutrophils requires NF-kappa B activity but is independent of TNF alpha signaling in mouse skin in vivo
  2. Cataisson, C.; Pearson, A. J.; Torgerson, S.; Nedospasov, S. A.; Yuspa, S. H.
  3. Journal of Immunology. 2005, FEB 1; 174(3): 1686-1692.
  1. 7.   Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C)
  2. Tamamura, H.; Sigano, D. M.; Lewin, N. E.; Peach, M. L.; Nicklaus, M. C.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2004, SEP 23; 47(20): 4858-4864.
  1. 8.   Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms
  2. Hou, D. X.; Kai, K.; Li, J. J.; Lin, S. G.; Terahara, N.; Wakamatsu, M.; Fujii, M.; Young, M. R.; Colburn, N.
  3. Carcinogenesis. 2004 25(1): 29-36.
  1. 9.   Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKC alpha
  2. Garcia-Bermejo, M. L.; Leskow, F. C.; Fujii, T.; Wang, Q. M.; Blumberg, P. M.; Ohba, M.; Kuroki, T.; Han, K. C.; Lee, J.; Marquez, V. E.; Kazanietz, M. G.
  3. Journal of Biological Chemistry. 2002 277(1): 645-655.
  1. 10.   Tumor promoter-induced ornithine decarboxylase gene expression occurs independently of AP-1 activation
  2. Jansen, A. P.; Colburn, N. H.; Verma, A. K.
  3. Oncogene. 1999 18(42): 5806-5813.
  1. 11.   A Dominant Negative Mutant of Jun Blocking 12-O-Tetradecanoylphorbol-13-Acetate-Induced Invasion in Mouse Keratinocytes
  2. Dong, Z. G.; Crawford, H. C.; Lavrovsky, V.; Taub, D.; Watts, R.; Matrisian, L. M.; Colburn, N. H.
  3. Molecular Carcinogenesis. 1997 19(3): 204-212.
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