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  1. 1.   Improved Production of Class I Phosphatidylinositol 4,5-bisphosphate 3-kinase
  2. Messing,Simon; Widmeyer, Stephanie R T; Denson,John-Paul; Mehalko,Jennifer; Wall,Vanessa; Drew,Matt; Snead,Kelly; Hong,Min; Grose,Carissa; Esposito,Dom; Gillette,Bill
  3. Protein Expression and Purification. 2024, Aug 20; 106582.
  1. 2.   Calmodulin (CaM) Activates PI3K alpha by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85 alpha
  2. Zhang,Mingzhen; Li, Zhigang; Wang, Guanqiao; Jang,Hyunbum; Sacks, David B.; Zhang, Jian; Gaponenko, Vadim; Nussinov,Ruth
  3. JOURNAL OF PHYSICAL CHEMISTRY B. 2018, Dec 13; 122(49): 11137-11146.
  1. 3.   Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit
  2. Wang, Guanqiao; Zhang, Mingzhen; Jang, Hyunbum; Lu, Shaoyong; Lin, Shizhou; Chen, Guoqiang; Nussinov, Ruth; Zhang, Jian; Gaponenko, Vadim
  3. Biochemistry. 2018, Mar 27; 57(12): 1917-1928.
  1. 4.   Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy
  2. Logue, J. S.; Morrison, D. K.
  3. Genes & Development. 2012, Apr; 26(7): 641-650.
  1. 5.   Protein Kinase C zeta Mediates mu-Opioid Receptor-induced Cross-desensitization of Chemokine Receptor CCR5
  2. Song, C. C.; Rahim, R. T.; Davey, P. C.; Bednar, F.; Bardi, G.; Zhang, L.; Zhang, N.; Oppenheim, J. J.; Rogers, T. J.
  3. Journal of Biological Chemistry. 2011, Jun; 286(23): 20354-20365.
  1. 6.   Association of Src-Related Kinase Lyn with the Interleukin-2 Receptor and Its Role in Maintaining Constitutive Phosphorylation of JAK/STAT in Human T-Cell Leukemia Virus Type 1-Transformed T Cells
  2. Shuh, M. S. M.; Morse, B. A.; Heidecker, G.; Derse, D.
  3. Journal of Virology. 2011, May; 85(9): 4623-4627.
  1. 7.   Friend Spleen Focus-Forming Virus Activates the Tyrosine Kinase sf-Stk and the Transcription Factor PU.1 to Cause a Multi-Stage Erythroleukemia in Mice
  2. Cmarik, J.; Ruscetti, S.
  3. Viruses-Basel. 2010, Oct; 2(10): 2235-2257.
  1. 8.   Role of Phosphatidylinositol 3-Kinase in Friend Spleen Focus-Forming Virus-Induced Erythroid Disease
  2. Umehara, D.; Watanabe, S.; Ochi, H.; Anai, Y.; Ahmed, N.; Kannagi, M.; Hanson, C.; Ruscetti, S.; Nishigaki, K.
  3. Journal of Virology. 2010, Aug; 84(15): 7675-7682.
  1. 9.   Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1
  2. Fer, N. D.; Shoemaker, R. H.; Monks, A.
  3. Journal of Experimental & Clinical Cancer Research. 2010, Jul; 29: 7.
  1. 10.   Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1
  2. Gruber, S. G.; Luciani, M. G.; Grundtner, P.; Zdanov, A.; Gasche, C.
  3. European Journal of Immunology. 2008 38(12): 3365-3375.
  1. 11.   Role of the intracellular domain of IL-7 receptor in T cell development
  2. Jiang, Q.; Huang, J.; Li, W. Q.; Cavinato, T.; Keller, J. R.; Durum, S. K.
  3. Journal of Immunology. 2007, Jan; 178(1): 228-234.
  1. 12.   CK2 is a component of the KSR1 scaffold complex that contributes to Raf kinase activation
  2. Ritt, D. A.; Zhou, M.; Conrads, T. P.; Veenstra, T. D.; Copeland, T. D.; Morrison, D. K.
  3. Current Biology. 2007, Jan; 17(2): 179-184.
  1. 13.   Gab1 is required for cell cycle transition, cell proliferation, and transformation induced by an oncogenic Met receptor
  2. Mood, K.; Saucier, C.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Molecular Biology of the Cell. 2006, Sep; 17(9): 3717-3728.
  1. 14.   Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma
  2. Rudelius, M.; Pittaluga, S.; Nishizuka, S.; Pham, T. H. T.; Fend, F.; Jaffe, E. S.; Quintanilla-Martinez, L.; Raffeld, M.
  3. Blood. 2006, Sep; 108(5): 1668-1676.
  1. 15.   Oncogenic met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling
  2. Mood, K.; Saucier, C.; Ishimura, A.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Journal of Cellular Physiology. 2006, APR; 207(1): 271-285.
  1. 16.   Ligand-induced partitioning of human CXCR1 chemokine receptors with lipid raft microenvironments facilitates G-protein-dependent signaling
  2. Jiao, X. M.; Zhang, N.; Xu, X. H.; Oppenheim, J. J.; Jin, T.
  3. Molecular and Cellular Biology. 2005, JUL; 25(13): 5752-5762.
  1. 17.   Phosphorylation of Ser(24) in the pleckstrin homology domain of insulin receptor substrate-1 by mouse Pelle-like kinase/interleukin-1 receptor-associated kinase - Cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance
  2. Kim, J. A.; Yeh, D. C.; Ver, M.; Li, Y. H.; Carranza, A.; Conrads, T. P.; Veenstra, T. D.; Harrington, M. A.; Quon, M. J.
  3. Journal of Biological Chemistry. 2005, JUN 17; 280(24): 23173-23183.
  1. 18.   Topotecan blocks hypoxia-inducible factor-1 alpha, and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells
  2. Beppu, Y.; Nakamura, K.; Linehan, W. M.; Rapisarda, A.; Thiele, C. J.
  3. Cancer Research. 2005, JUN 1; 65(11): 4775-4781.
  1. 19.   Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells
  2. Sun, R. H.; Gao, P.; Chen, L.; Ma, D. L.; Wang, J. M.; Oppenheim, J. J.; Zhang, N.
  3. Cancer Research. 2005, FEB 15; 65(4): 1433-1441.
  1. 20.   Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase
  2. Liu, Y. S.; Shreder, K. R.; Gai, W. Z.; Corral, S.; Ferris, D. K.; Rosenblum, J. S.
  3. Chemistry & Biology. 2005, JAN; 12(1): 99-107.
  1. 21.   Lyn contributes to regulation of multiple Kit-dependent signaling pathways in murine bone marrow mast cells
  2. Shivakrupa, R.; Linnekin, D.
  3. Cellular Signalling. 2005, JAN; 17(1): 103-109.
  1. 22.   7-hydroxystaurosporine (UCN-01) inhibition of Akt Thr(308) but not Ser(473) phosphorylation: A basis for decreased insulin-stimulated glucose transport
  2. Kondapaka, S. B.; Zarnowski, M. J.; Yver, D. R.; Sausville, E. A.; Cushman, S. W.
  3. Clinical Cancer Research. 2004, NOV 1; 10(21): 7192-7198.
  1. 23.   Synergistic growth of stem cell factor and granulocyte macrophage colony-stimulating factor involves kinase-dependent and -independent contributions from c-Kit
  2. Lennartsson, J.; Shivakrupa, R.; Linnekin, D.
  3. Journal of Biological Chemistry. 2004, OCT 22; 279(43): 44544-44553.
  1. 24.   Contribution of JNK, Mek, Mos and PI-3K signaling to GVBD in Xenopus oocytes
  2. Mood, K.; Bong, Y. S.; Lee, H. S.; Ishimura, A.; Daar, I. O.
  3. Cellular Signalling. 2004, MAY; 16(5): 631-642.
  1. 25.   Critical prosurvival roles for C/EBP beta and insulin-like growth factor I in macrophage tumor cells
  2. Wessells, J.; Yakar, S.; Johnson, P. F.
  3. Molecular and Cellular Biology. 2004 24(8): 3238-3250.
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