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  1. 1.   RAS and SHOC2 Roles in RAF Activation and Therapeutic Considerations
  2. Bonsor,Daniel; Simanshu,Dhirendra
  3. Annual Review of Cancer Biology. 2024, Jun; 8: 97-113.
  1. 2.   Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3? protein and represses lung cancer metastasis
  2. Chen,Zibo; Zheng, Lin; Chen, Yulong; Liu,Xiuxia; Kawakami, Masanori; Mustachio, Lisa Maria; Roszik, Jason; Ferry-Galow,Katherine; Parchment,Ralph; Liu, Xin; Andresson,Thorkell; Duncan,Gerard; Kurie, Jonathan M; Rodriguez-Canales, Jaime; Liu,Xi; Dmitrovsky,Ethan
  3. Cancer Biology & Therapy. 2022, Dec 31; 23(1): 265-280.
  1. 3.   Antisense pairing and SNORD13 structure guide RNA cytidine acetylation
  2. Thalalla Gamage,Supuni; Bortolin-Cavaillé, Marie-Line; Link, Courtney; Bryson, Keri; Sas-Chen, Aldema; Schwartz, Schraga; Cavaillé, Jérôme; Meier,Jordan
  3. RNA (New York, N.Y.). 2022, Sep 20;
  1. 4.   Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas
  2. Barreca, Marilia; Spanò, Virginia; Rocca, Roberta; Bivacqua, Roberta; Abel, Anne-Catherine; Maruca, Annalisa; Montalbano, Alessandra; Raimondi, Maria Valeria; Tarantelli, Chiara; Gaudio, Eugenio; Cascione, Luciano; Rinaldi, Andrea; Bai,Ruoli; Steinmetz, Michel O; Prota, Andrea E; Alcaro, Stefano; Hamel, Ernest; Bertoni, Francesco; Barraja, Paola
  3. European Journal of Medicinal Chemistry. 2022, Sep 08; 243: 114744.
  1. 5.   Identification of a CD4-binding site-directed antibody with ADCC activity from a chronic HIV-1B'-infected Chinese donor
  2. Hu, Yuanyuan; Li, Dan; Fu, Hongyang; Hao, Yanling; Ren, Li; Wang, Shuo; Hu,Xintao; Shao, Yiming; Hong, Kunxue; Wang, Zheng
  3. Virus research. 2021, Sep; 302: 198470.
  1. 6.   EML4-ALK induces cellular senescence in mortal normal human cells and promotes anchorage-independent growth in hTERT-transduced normal human cells
  2. Miyanaga, Akihiko; Matsumoto, Masaru; Beck, Jessica A.; Horikawa, Izumi; Oike, Takahiro; Okayama, Hirokazu; Tanaka, Hiromi; Burkett,Sandra; Robles, Ana I.; Khan, Mohammed; Lissa, Delphine; Seike, Masahiro; Gemma, Akihiko; Mano, Hiroyuki; Harris, Curtis C.
  3. BMC Cancer. 2021, Mar 24; 21(1):
  1. 7.   A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma
  2. Gaikwad, Snehal M; Phyo, Zaw; Arteaga, Anaisa Quintanilla; Gorjifard, Sayeh; Calabrese,Dave; Connors, Daniel; Huang, Jing; Michalowski, Aleksandra M; Zhang, Shuling; Liu, Zheng-Gang; Schneekloth,Jay; Mock, Beverly A
  3. Cancers. 2020, Oct 13; 12(10): pii: E2952.
  1. 8.   New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action
  2. Daidone, Giuseppe; D'Anneo, Antonella; Raimondi, Maria Valeria; Raffa, Demetrio; Hamel,Ernest; Plescia, Fabiana; Lauricella, Marianna; Maggio, Benedetta
  3. Bioorganic chemistry. 2020, AUG; 101: pii: 103989.
  1. 9.   Significance of pro-angiogenic estrogen metabolites in normal follicular development and follicular growth arrest in polycystic ovary syndrome
  2. Henríquez, Soledad; Kohen, Paulina; Xu,Xia; Villarroel, Claudio; Muñoz, Alex; Godoy, Ana; Strauss, Jerome F; Devoto, Luigi
  3. Human reproduction (Oxford, England). 2020, JUL; 35(7): 1655-1665.
  1. 10.   Identification of Sec23ip, part of 14-3-3? protein network, as a regulator of acute steroidogenesis in MA-10 Leydig cells
  2. Aghazadeh, Yasaman; Venugopal, Sathvika; Martinez-Arguelles, Daniel Benjamin; Boisvert, Annie; Blonder,Josip; Papadopoulos, Vassilios
  3. Endocrinology. 2020, Feb 1; 161(2):
  1. 11.   Acetylation of Cytidine in mRNA Promotes Translation Efficiency
  2. Arango, Daniel; Sturgill, David; Alhusaini, Najwa; Dillman, Allissa A.; Sweet, Thomas J.; Hanson, Gavin; Hosogane, Masaki; Sinclair, Wilson R.; Nanan, Kyster K.; Mandler, Mariana D.; Fox,Stephen; Zengeya, Thomas T.; Andresson,Thorkell; Meier,Jordan; Coller, Jeffery; Oberdoerffer, Shalini
  3. CELL. 2018, Dec 13; 175(7): 1872-1886.e24.
  1. 12.   Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family
  2. Ochoa-Lizarralde, Borja; Gao, Yong-Guang; Popov, Alexander N; Samygina, Valeria R; Zhai, Xiuhong; Mishra, Shrawan K; Boldyrev, Ivan A; Molotkovsky, Julian G; Simanshu, Dhirendra; Patel, Dinshaw J; Brown, Rhoderick E; Malinina, Lucy
  3. Journal of Biological Chemistry. 2018, Sep 11; pii: jbc.RA117.000733.
  1. 13.   Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies
  2. Duan, Hongying; Chen, Xuejun; Boyington, Jeffrey C; Cheng, Cheng; Zhang, Yi; Jafari, Alexander J; Stephens, Tyler; Tsybovsky, Yaroslav; Kalyuzhniy, Oleksandr; Zhao, Peng; Menis, Sergey; Nason, Martha C; Normandin, Erica; Mukhamedova, Maryam; DeKosky, Brandon J; Wells, Lance; Schief, William R; Tian, Ming; Alt, Frederick W; Kwong, Peter D; Mascola, John R
  3. Immunity. 2018, Aug 21; 49(2): 301-311.e5.
  1. 14.   Estrogen metabolism in the human lung: impact of tumorigenesis, smoke, sex and race/ethnicity
  2. Peng, Jing; Meireles, Sibele I; Xu, Xia; Smith, William E; Slifker, Michael J; Riel, Stacy L; Zhai, Shumenghui; Zhang, Guo; Ma, Xiang; Kurzer, Mindy S; Ma, Grace X; Clapper, Margie L
  3. Oncotarget. 2017, Dec 05; 8(63): 106778-106789.
  1. 15.   3-Aroyl-1,4-diarylpyrroles Inhibit Chronic Myeloid Leukemia Cell Growth through an Interaction with Tubulin
  2. La Regina, Giuseppe; Bai, Ruoli; Coluccia, Antonio; Famiglini, Valeria; Passacantilli, Sara; Naccarato, Valentina; Ortar, Giorgio; Mazzoccoli, Carmela; Ruggieri, Vitalba; Agriesti, Francesca; Piccoli, Claudia; Tataranni, Tiziana; Nalli, Marianna; Brancale, Andrea; Vultaggio, Stefania; Mercurio, Ciro; Varasi, Mario; Saponaro, Concetta; Sergio, Sara; Maffia, Michele; Coluccia, Addolorata Maria Luce; Hamel, Ernest; Silvestri, Romano
  3. ACS Medicinal Chemistry Letters. 2017, Apr 26; 8(5): 521-526.
  1. 16.   Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation
  2. Zhou, Tongqing; Doria-Rose, Nicole A; Cheng, Cheng; Stewart-Jones, Guillaume B E; Chuang, Gwo-Yu; Chambers, Michael; Druz, Aliaksandr; Geng, Hui; McKee, Krisha; Kwon, Young Do; O'Dell, Sijy; Sastry, Mallika; Schmidt, Stephen D; Xu, Kai; Chen, Lei; Chen, Rita E; Louder, Mark K; Pancera, Marie; Wanninger, Timothy G; Zhang, Baoshan; Zheng, Anqi; Farney, S Katie; Foulds, Kathryn E; Georgiev, Ivelin S; Joyce, M Gordon; Lemmin, Thomas; Narpala, Sandeep; Rawi, Reda; Soto, Cinque; Todd, John-Paul; Shen, Chen-Hsiang; Tsybovsky, Yaroslav; Yang, Yongping; Zhao, Peng; Haynes, Barton F; Stamatatos, Leonidas; Tiemeyer, Michael; Wells, Lance; Scorpio, Diana G; Shapiro, Lawrence; McDermott, Adrian B; Mascola, John R; Kwong, Peter D
  3. Cell Reports. 2017, Apr 25; 19(4): 719-732.
  1. 17.   Integrated genomic and molecular characterization of cervical cancer
  2. Burk, Robert D.; Chen, Zigui; Saller, Charles; Tarvin, Katherine; Carvalho, Andre L.; Scapulatempo-Neto, Cristovam; Silveira, Henrique C.; Fregnani, Jose H.; Creighton, Chad J.; Anderson, Matthew L.; Castro, Patricia; Wang, Sophia S.; Yau, Christina; Benz, Christopher; Robertson, A. Gordon; Mungall, Karen; Lim, Lynette; Bowlby, Reanne; Sadeghi, Sara; Brooks, Denise; Sipahimalani, Payal; Mar, Richard; Ally, Adrian; Clarke, Amanda; Mungall, Andrew J.; Tam, Angela; Lee, Darlene; Chuah, Eric; Schein, Jacqueline E.; Tse, Kane; Kasaian, Katayoon; Ma, Yussanne; Marra, Marco A.; Mayo, Michael; Balasundaram, Miruna; Thiessen, Nina; Dhalla, Noreen; Carlsen, Rebecca; Moore, Richard A.; Holt, Robert A.; Jones, Steven J. M.; Wong, Tina; Pantazi, Angeliki; Parfenov, Michael; Kucherlapati, Raju; Hadjipanayis, Angela; Seidman, Jonathan; Kucherlapati, Melanie; Ren, Xiaojia; Xu, Andrew W.; Yang, Lixing; Park, Peter J.; Lee, Semin; Rabeno, Brenda; Huelsenbeck-Dill, Lori; Borowsky, Mark; Cadungog, Mark; Iacocca, Mary; Petrelli, Nicholas; Swanson, Patricia; Ojesina, Akinyemi I.; Le, Xuan; Sandusky, George; Adebamowo, Sally N.; Akeredolu, Teniola; Adebamowo, Clement; Reynolds, Sheila M.; Shmulevich, Ilya; Shelton, Candace; Crain, Daniel; Mallery, David; Curley, Erin; Gardner, Johanna; Penny, Robert; Morris, Scott; Shelton, Troy; Liu, Jia; Lolla, Laxmi; Chudamani, Sudha; Wu, Ye; Birrer, Michael; McLellan, Michael D.; Bailey, Matthew H.; Miller, Christopher A.; Wyczalkowski, Matthew A.; Fulton, Robert S.; Fronick, Catrina C.; Lu, Charles; Mardis, Elaine R.; Appelbaum, Elizabeth L.; Schmidt, Heather K.; Fulton, Lucinda A.; Cordes, Matthew G.; Li, Tiandao; Ding, Li; Wilson, Richard K.; Rader, Janet S.; Behmaram, Behnaz; Uyar, Denise; Bradley, William; Wrangle, John; Pastore, Alessandro; Levine, Douglas A.; Dao, Fanny; Gao, Jianjiong; Schultz, Nikolaus; Sander, Chris; Ladanyi, Marc; Einstein, Mark; Teeter, Randall; Benz, Stephen; Wentzensen, Nicolas; Felau, Ina; Zenklusen, Jean C.; Bodelon, Clara; Demchok, John A.; Yang, Liming; Sheth, Margi; Ferguson, Martin L.; Tarnuzzer, Roy; Yang, Hannah; Schiffman, Mark; Zhang, Jiashan; Wang, Zhining; Davidsen, Tanja; Olaniyan, Olayinka; Hutter, Carolyn M.; Sofia, Heidi J.; Gordenin, Dmitry A.; Chan, Kin; Roberts, Steven A.; Klimczak, Leszek J.; Van Waes, Carter; Chen, Zhong; Saleh, Anthony D.; Cheng, Hui; Parfitt, Jeremy; Bartlett, John; Albert, Monique; Arnaout, Angel; Sekhon, Harman; Gilbert, Sebastien; Peto, Myron; Myers, Jerome; Harr, Jodi; Eckman, John; Bergsten, Julie; Tucker, Kelinda; Zach, Leigh Anne; Karlan, Beth Y.; Lester, Jenny; Orsulic, Sandra; Sun, Qiang; Naresh, Rashi; Pihl, Todd; Wan, Yunhu; Zaren, Howard; Sapp, Jennifer; Miller, Judy; Drwiega, Paul; Ojesina, Akinyemi I.; Murray, Bradley A.; Zhang, Hailei; Cherniack, Andrew D.; Sougnez, Carrie; Pedamallu, Chandra Sekhar; Lichtenstein, Lee; Meyerson, Matthew; Noble, Michael S.; Heiman, David I.; Voet, Doug; Getz, Gad; Saksena, Gordon; Kim, Jaegil; Shih, Juliann; Cho, Juok; Lawrence, Michael S.; Gehlenborg, Nils; Lin, Pei; Beroukhim, Rameen; Frazer, Scott; Gabriel, Stacey B.; Schumacher, Steven E.; Leraas, Kristen M.; Lichtenberg, Tara M.; Zmuda, Erik; Bowen, Jay; Frick, Jessica; Gastier-Foster, Julie M.; Wise, Lisa; Gerken, Mark; Ramirez, Nilsa C.; Danilova, Ludmila; Cope, Leslie; Baylin, Stephen B.; Salvesen, Helga B.; Vellano, Christopher P.; Ju, Zhenlin; Diao, Lixia; Zhao, Hao; Chong, Zechen; Ryan, Michael C.; Martinez-Ledesma, Emmanuel; Verhaak, Roeland G.; Byers, Lauren Averett; Yuan, Yuan; Chen, Ken; Ling, Shiyun; Mills, Gordon B.; Lu, Yiling; Akbani, Rehan; Seth, Sahil; Liang, Han; Wang, Jing; Han, Leng; Weinstein, John N.; Bristow, Christopher A.; Zhang, Wei; Mahadeshwar, Harshad S.; Sun, Huandong; Tang, Jiabin; Zhang, Jianhua; Song, Xingzhi; Protopopov, Alexei; Shaw, Kenna R. Mills; Chin, Lynda; Olabode, Oluwole; Ojesina, Akinyemi I.; DiSaia, Philip; Radenbaugh, Amie; Haussler, David; Zhu, Jingchun; Stuart, Josh; Chalise, Prabhakar; Koestler, Devin; Fridley, Brooke L.; Godwin, Andrew K.; Madan, Rashna; Ciriello, Giovanni; Martinez, Cathleen; Higgins, Kelly; Bocklage, Therese; Auman, J. Todd; Perou, Charles M.; Tan, Donghui; Parker, Joel S.; Hoadley, Katherine A.; Wilkerson, Matthew D.; Mieczkowski, Piotr A.; Skelly, Tara; Veluvolu, Umadevi; Hayes, D. Neil; Rathmell, W. Kimryn; Hoyle, Alan P.; Simons, Janae V.; Wu, Junyuan; Mose, Lisle E.; Soloway, Matthew G.; Balu, Saianand; Meng, Shaowu; Jefferys, Stuart R.; Bodenheimer, Tom; Shi, Yan; Roach, Jeffrey; Thorne, Leigh B.; Boice, Lori; Huang, Mei; Jones, Corbin D.; Zuna, Rosemary; Walker, Joan; Gunderson, Camille; Snowbarger, Carie; Brown, David; Moxley, Katherine; Moore, Kathleen; Andrade, Kelsi; Landrum, Lisa; Mannel, Robert; McMeekin, Scott; Johnson, Starla; Nelson, Tina; Elishaev, Esther; Dhir, Rajiv; Edwards, Robert; Bhargava, Rohit; Tiezzi, Daniel G.; Andrade, Jurandyr M.; Noushmehr, Houtan; Carlotti, Carlos Gilberto; Tirapelli, Daniela Pretti da Cunha; Weisenberger, Daniel J.; Van Den Berg, David J.; Maglinte, Dennis T.; Bootwalla, Moiz S.; Lai, Phillip H.; Triche, Timothy; Swisher, Elizabeth M.; Agnew, Kathy J.; Shelley, Carl Simon; Laird, Peter W.; Schwarz, Julie; Grigsby, Perry; Mutch, David
  3. Nature. 2017, Mar 16; 543(7645): 378-384.
  1. 18.   The frequency of alpha(4)beta(7)(high) memory CD4(+) T cells correlates with susceptibility to rectal simian immunodeficiency virus infection
  2. Martinelli, E.; Veglia, F.; Goode, D.; Guerra-Perez, N.; Aravantinou, M.; Arthos, J.; Piatak, M., Jr.; Lifson, J. D.; Blanchard, J.; Gettie, A.; Robbiani, M.
  3. Journal of acquired immune deficiency syndromes (1999). 2013, 1-Dec; 64(4): 325-31.
  1. 19.   The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2
  2. Pasek, M.; Ramakrishnan, B.; Boeggeman, E.; Mercer, N.; Dulcey, A. E.; Griffiths, G. L.; Qasba, P. K.
  3. Glycobiology. 2012, Mar; 22(3): 379-388.
  1. 20.   Microwave-Based Reaction Screening: Tandem Retro-Diels Alder/Diels-Alder Cycloadditions of o-Quinol Dimers
  2. Dong, S. W.; Cahill, K. J.; Kang, M. I.; Colburn, N. H.; Henrich, C. J.; Wilson, J. A.; Beutler, J. A.; Johnson, R. P.; Porco, J. A.
  3. Journal of Organic Chemistry. 2011, Nov; 76(21): 8944-8954.
  1. 21.   Depletion of CD4(+) T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques
  2. Ortiz, A. M.; Klatt, N. R.; Li, B.; Yi, Y.; Tabb, B.; Hao, X. P.; Sternberg, L.; Lawson, B.; Carnathan, P. M.; Cramer, E. M.; Engram, J. C.; Little, D. M.; Ryzhova, E.; Gonzalez-Scarano, F.; Paiardini, M.; Ansari, A. A.; Ratcliffe, S.; Else, J. G.; Brenchley, J. M.; Collman, R. G.; Estes, J. D.; Derdeyn, C. A.; Silvestri, G.
  3. Journal of Clinical Investigation. 2011, Nov; 121(11): 4433-4445.
  1. 22.   14-3-3 Proteins: Diverse functions in cell proliferation and cancer progression
  2. Freeman, A. K.; Morrison, D. K.
  3. Seminars in Cell & Developmental Biology. 2011, Sep; 22(7): 681-687.
  1. 23.   The Role of ITCH Protein in Human T-cell Leukemia Virus Type 1 Release
  2. Dorjbal, B.; Derse, D.; Lloyd, P.; Soheilian, F.; Nagashima, K.; Heidecker, G.
  3. Journal of Biological Chemistry. 2011, Sep; 286(36): 31092-31104.
  1. 24.   Synthetic and Application Perspectives of Azapodophyllotoxins: Alternative Scaffolds of Podophyllotoxin
  2. Kumar, A.; Kumar, V.; Alegria, A. E.; Malhotra, S. V.
  3. Current Medicinal Chemistry. 2011, Sep; 18(25): 3853-3870.
  1. 25.   Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1 alpha in Advanced Solid Tumors
  2. Kummar, S.; Raffeld, M.; Juwara, L.; Horneffer, Y.; Strassberger, A.; Allen, D.; Steinberg, S. M.; Rapisarda, A.; Spencer, S. D.; Figg, W. D.; Chen, X. H.; Turkbey, I. B.; Choyke, P.; Murgo, A. J.; Doroshow, J. H.; Melillo, G.
  3. Clinical Cancer Research. 2011, Aug; 17(15): 5123-5131.
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