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  1. 1.   Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine
  2. Maciag,Anna; Yang, Yue; Sharma,Alok; Turner,David; Dehart,Caroline; Abdelkarim, Hazem; Fan,Lixin; Smith,Brian; Kumari,Vandana; Dyba,Marcin; Rigby,Megan; Castillo Badillo,Jean; Adams, Lauren; Fornelli, Luca; Fox, Stephen; Brafman, Alla; Turbyville,Thomas; Gillette,William; Messing,Simon; Agamasu, Constance; Wolfe, Andrew L; Gysin, Stephan; Chan, Albert H; Simanshu,Dhirendra; Esposito,Dominic; Chertov,Oleg; Stephen,Andrew; Arkin, Michelle; Renslo, Adam; Kelleher, Neil L; Gaponenko, Vadim; Lightstone, Felice C; Nissley,Dwight; McCormick, Frank
  3. Proceedings of the National Academy of Sciences of the United States of America. 2025, May 13; 122(19): e2410766122.
  1. 2.   Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha-crystalline beta
  2. Ganta, Krishna Kumar; McManus, Margaret; Blanc, Ross; Wang, Qixin; Jung, Wonyeong; Brody, Robin; Carrington,Mary; Paris, Robert; Chandramouli, Sumana; McNamara, Ryan P; Luzuriaga, Katherine
  3. Cell Reports. 2025, May 13; 44(5): 115709.
  1. 3.   Whole-genome sequencing of 1,083 HPV45 cases and controls identifies genetic variants associated with glandular cervical lesions
  2. Koestler, Aimee J; Nelson, Chase W; Yeager,Stella; Chen, Zigui; Mishra,Sambit; Burdett, Laurie; Dean, Michael; Suh-Burgmann, Elizabeth; Lorey, Thomas; Clifford, Gary M; Wentzensen, Nicolas; Castle, Philip E; Schiffman, Mark; Burk, Robert D; Mirabello, Lisa
  3. International Journal of Cancer. 2025, May 05;
  1. 4.   Elements in the 5' Untranslated Region of Viral RNA Important for HIV Gag Recognition and Cross-Packaging
  2. Cheng,Zetao; Nikolaitchik,Olga; Duchon,Alice; Rawson, Jonathan M O; Pathak,Vinay; Hu,Wei-Shau
  3. Viruses. 2025, Apr 10; 17(4): 551.
  1. 5.   Inhibition of Ribosome Biogenesis in vivo Causes p53-Dependent Death and p53-Independent Dysfunction
  2. Cho, Charles J; Nguyen, Thanh; Rougeau, Amala K; Huang, Yang-Zhe; To, Sarah; Lin, Xiaobo; Thalalla Gamage,Supuni; Meier,Jordan; Mills, Jason C
  3. Cellular and Molecular Gastroenterology and Hepatology. 2025, Mar 11; 101496.
  1. 6.   Prior SARS-Cov-2 infection affects adaptive immune responses to Omicron BA.4/BA.5 mRNA booster
  2. Wachter, Brianna T; Xu, Qin; Shi, Lihong; Burbelo, Peter D; Myint-Hpu, Kathy; Schwartzberg, Pamela L; Rehman,Tauseef; Dewar,Robin; Boswell, Kristin L; Koup, Richard A; Oguz, Cihan; Imberti, Luisa; Bellusci, Lorenza; Pourhashemi, Sara; Khurana, Surender; Manthiram, Kalpana; Notarangelo, Luigi D; Delmonte, Ottavia M
  3. The journal of Allergy and Clinical Immunology. . 2025, Mar 03;
  1. 7.   Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350
  2. Joyce, M Gordon; Bu, Wei; Chen, Wei-Hung; Gillespie, Rebecca A; Andrews, Sarah F; Wheatley, Adam K; Tsybovsky,Yaroslav; Jensen, Jaime L; Stephens,Tyler; Prabhakaran, Madhu; Fisher, Brian E; Narpala, Sandeep R; Bagchi, Meghna; McDermott, Adrian B; Nabel, Gary J; Kwong, Peter D; Mascola, John R; Cohen, Jeffrey I; Kanekiyo, Masaru
  3. Immunity. 2025, Feb 11; 58(2): 295-308.e5. .
  1. 8.   Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition
  2. Li, Haojian; Furusawa, Takashi; Cavero, Renzo; Xiao, Yunjie; Chari,Raj; Wu,Xiaolin; Sun, David; Hartmann, Oliver; Dhall, Anjali; Holewinski,Ronald; Andresson,Thorkell; Karim,Baktiar; Villamor-Payà, Marina; Gallardo, Devorah; Day, Chi-Ping; Pal, Lipika R; Nair, Nishanth Ulhas; Ruppin, Eytan; Aladjem, Mirit I; Pommier, Yves; Diefenbacher, Markus E; Lim, Jung Mi; Levine, Rodney L; Stracker, Travis H; Weyemi, Urbain
  3. Redox Biology. 2025, Jan 19; 80: 103503.
  1. 9.   A KSHV RNA-binding protein promotes FOS to inhibit nuclease AEN and transactivate RGS2 for AKT phosphorylation
  2. Majerciak,Vladimir; Alvarado-Hernandez, Beatriz; Ma, Yanping; Duduskar, Shivalee; Lobanov, Alexei; Cam, Maggie; Zheng,Zhi-Ming
  3. mBio. 2024, Dec 10; e0317224.
  1. 10.   SNARE mimicry by the CD225 domain of IFITM3 enables regulation of homotypic late endosome fusion
  2. Rahman, Kazi; Wilt,Isaiah; Jolley, Abigail A; Chowdhury,Bhabadeb; Datta, Siddhartha A K; Compton,Alex
  3. The EMBO Journal. 2024, Dec 09;
  1. 11.   Insights into biofilm architecture and maturation enable improved clinical strategies for exopolysaccharide-targeting therapeutics
  2. Temme,Joel; Tan, Zibin; Li,Mi; Yang,Mo; Wlodawer,Alexander; Huang, Xuefei; Schneekloth,Jay; Gildersleeve,Jeffrey
  3. Cell Chemical Biology. 2024, Dec 02;
  1. 12.   Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors
  2. Krushkal, Julia; Zhao, Yingdong; Roney, Kyle; Zhu, Weimin; Brooks,Alan; Wilsker,Deborah; Parchment, Ralph E; McShane, Lisa M; Doroshow, James H
  3. Epigenetics. 2024, Dec; 19(1): 2309824.
  1. 13.   Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activity
  2. Hangasky, John A; Fernández, Rocío Del Valle; Stellas,Dimitris; Hails, Guillermo; Karaliota,Sevasti; Ashley, Gary W; Felber,Barbara; Pavlakis,George; Santi, Daniel V
  3. Frontiers in Immunology. 2024, Nov 4; 15: 1458145.
  1. 14.   Translation of HIV-1 unspliced RNA is regulated by 5' untranslated region structure
  2. Cheng,Zetao; Islam,Mohammad Saiful; Kanlong, Joseph G; Sheppard, Madeline; Seo, Heewon; Nikolaitchik,Olga; Kearse, Michael G; Pathak,Vinay; Musier-Forsyth, Karin; Hu,Wei-Shau
  3. Journal of Virology. 2024, Sep 24; e0116024.
  1. 15.   Guanylate-binding protein 5 antagonizes viral glycoproteins independently of furin processing
  2. Veler,Hana; Lun, Cheng Man; Waheed,Abdul; Freed,Eric
  3. mBio. 2024, Aug 30; e0208624.
  1. 16.   Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies
  2. Meyer, Christian T; Smith, Brianna N; Wang, Jing; Teuscher, Kevin B; Grieb, Brian C; Howard, Gregory C; Silver, Alexander J; Lorey, Shelly L; Stott,Gordon; Moore,Bill; Lee, Taekyu; Savona, Michael R; Weissmiller, April M; Liu, Qi; Quaranta, Vito; Fesik, Stephen W; Tansey, William P
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Aug 27; 121(35): e2408889121.
  1. 17.   Improved Production of Class I Phosphatidylinositol 4,5-bisphosphate 3-kinase
  2. Messing,Simon; Widmeyer, Stephanie R T; Denson,John-Paul; Mehalko,Jennifer; Wall,Vanessa; Drew,Matt; Snead,Kelly; Hong,Min; Grose,Carissa; Esposito,Dom; Gillette,Bill
  3. Protein Expression and Purification. 2024, Aug 20; 106582.
  1. 18.   Insights into gemcitabine resistance in pancreatic cancer: association with metabolic reprogramming and TP53 pathogenicity in patient derived xenografts
  2. Konaté, Mariam M; Krushkal, Julia; Li, Ming-Chung; Chen, Li; Kotliarov, Yuri; Palmisano, Alida; Pauly,Rini; Xie, Qian; Williams, P Mickey; McShane, Lisa M; Zhao, Yingdong
  3. Journal of Translational Medicine. 2024, Aug 05; 22(1): 733.
  1. 19.   Genome-scale exon perturbation screens uncover exons critical for cell fitness
  2. Xiao,Meisheng; Damodaran,Arun Prasath; Kumari,Bandana; Dickson, Ethan; Xing, Kun; On, Tyler A; Parab, Nikhil; King, Helen E; Perez, Alexendar R; Guiblet,Wilfried; Duncan,Gerard; Che,Anney; Chari,Raj; Andresson,Thorkell; Vidigal, Joana A; Weatheritt, Robert J; Aregger,Michael; Gonatopoulos Pournatzis,Thomas
  3. Molecular Cell. 2024, Jul 11; 84(13): 2553-2572.
  1. 20.   Enhancing precision in colorectal cancer surgery: development of an LGR5-targeting RSPO1 peptide mimetic as a contrast agent for intraoperative fluorescence molecular imaging
  2. Parasido, Erika; Ribeiro, Patricia; Chingle,Ramesh; Rohwetter, Thomas; Gupta, Nikita; Avetian, George; Bladelli, Elisa; Pierobon, Mariaelena; Chen, Yu; Tang, Qinggong; Schnermann,Martin; Rodriguez, Olga; Burke,Terrence; Burke, Terrence R; Albanese, Chris; Ihemelandu, Chukwuemeka
  3. Cell Cycle (Georgetown, Tex.). 2024, Jul 10; 1-12.
  1. 21.   Soluble form of the MDA5 protein in human sera
  2. Okamoto, Masaki; Zaizen, Yoshiaki; Kaieda, Shinjiro; Nouno, Takashi; Koga, Takuma; Matama, Goushi; Mitsuoka, Masahiro; Akiba, Jun; Yamada, Shintaro; Kato, Hiroki; Hoshino,Tomoaki
  3. Heliyon. 2024, Jun 15; 10(11): e31727.
  1. 22.   Attenuation of aggressive tumor progression of anaplastic thyroid cancer by p53
  2. Hwang, Eunmi; Kruhlak, Michael; Wong,Nathan; Chari,Raj; Kimura, Takahito; Cheng, Sheue-Yann
  3. American Journal of Cancer Research. 2024 14(9): 4429-4444.
  1. 23.   In Vivo Treatment with Insulin-like Growth Factor 1 Reduces CCR5 Expression on Vaccine-Induced Activated CD4+ T-Cells
  2. Bissa, Massimiliano; Galli, Veronica; Schifanella, Luca; Vaccari, Monica; Rahman, Mohammad Arif; Gorini, Giacomo; Binello, Nicolò; Sarkis, Sarkis; Gutowska, Anna; Silva de Castro, Isabela; Doster, Melvin N; Moles, Ramona; Ferrari, Guido; Shen, Xiaoying; Tomaras, Georgia D; Montefiori, David C; N'guessan, Kombo F; Paquin-Proulx, Dominic; Kozlowski, Pamela A; Venzon, David J; Choo-Wosoba, Hyoyoung; Breed,Matthew; Kramer,Josh; Franchini, Genoveffa
  3. Vaccines. 2023, Oct 30; 11(11):
  1. 24.   Methotrexate-based PROTACs as DHFR-specific chemical probes
  2. Rana, Sandeep; Dranchak, Patricia; Dahlin, Jayme L; Lamy, Laurence; Li,Wenqing; Oliphant, Erin; Shrimp, Jonathan H; Rajacharya, Girish H; Tharakan, Ravi; Holland, David O; Whitten, Apryl S; Wilson, Kelli M; Singh, Pankaj K; Durum,Scott; Tao, Dingyin; Rai, Ganesha; Inglese, James
  3. Cell Chemical Biology. 2023, Oct 17;
  1. 25.   Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity
  2. Tocco, Graziella; Canton, Serena; Laus, Antonio; Caboni, Pierluigi; Le Grice, Stuart F J; Tramontano, Enzo; Esposito, Francesca
  3. Molecules (Basel, Switzerland). 2023, Sep 19; 28(18):
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