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  1. 1.   Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity
  2. Tocco, Graziella; Canton, Serena; Laus, Antonio; Caboni, Pierluigi; Le Grice, Stuart F J; Tramontano, Enzo; Esposito, Francesca
  3. Molecules (Basel, Switzerland). 2023, Sep 19; 28(18):
  1. 2.   NF-kB Signaling Modulates miR-452-5p and miR-335-5p Expression to Functionally Decrease Epithelial Ovarian Cancer Progression in Tumor-Initiating Cells
  2. Kamdar, Rahul D; Harrington, Brittney S; Attar, Emma; Korrapati, Soumya; Shetty,Jyoti; Zhao,Yongmei; Tran,Bao; Wong, Nathan; House, Carrie D; Annunziata, Christina M
  3. International Journal of Molecular Sciences. 2023, Apr 25; 24(9):
  1. 3.   Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities
  2. Romagnoli, Romeo; Oliva, Paola; Prencipe, Filippo; Manfredini, Stefano; Budassi, Federica; Brancale, Andrea; Ferla, Salvatore; Hamel,Ernest; Corallo, Diana; Aveic, Sanja; Manfreda, Lorenzo; Mariotto, Elena; Bortolozzi, Roberta; Viola, Giampietro
  3. Pharmaceuticals (Basel, Switzerland). 2022, Aug 21; 15(8):
  1. 4.   Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents
  2. Oliva, Paola; Romagnoli, Romeo; Cacciari, Barbara; Manfredini, Stefano; Padroni, Chiara; Brancale, Andrea; Ferla, Salvatore; Hamel,Ernest; Corallo, Diana; Aveic, Sanja; Milan, Noemi; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta
  3. Pharmaceutics. 2022, Jun 02; 14(6):
  1. 5.   Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors
  2. Spano, Virginia; Barreca, Marilia; Rocca, Roberta; Bortolozzi, Roberta; Bai, Ruoli; Carbone, Anna; Raimondi, Maria Valeria; Piccionello, Antonio Palumbo; Montalbano, Alessandra; Alcaro, Stefano; Hamel, Ernest; Viola, Giampietro; Barraja, Paola
  3. European Journal of Medicinal Chemistry. 2021, Feb 15; 212
  1. 6.   Structure-Activity Relationships of Pyrazolo[1,5-a]pyrimidin-7(4H)-ones as Antitubercular Agents
  2. Oh, Sangmi; Libardo, M. Daben J.; Azeeza, Shaik; Pauly,Gary; Roma, Jose Santinni O.; Sajid, Andaleeb; Tateishi, Yoshitaka; Duncombe, Caroline; Goodwin, Michael; Ioerger, Thomas R.; Wyatt, Paul G.; Ray, Peter C.; Gray, David W.; Boshoff, Helena I. M.; Barry, Clifton E.
  3. ACS Infectious Diseases. 2021, Feb 12; 7(2): 479-492.
  1. 7.   Ascorbic Acid Promotes KIR Demethylation during Early NK Cell Differentiation
  2. Wu, Cheng-Ying; Zhang, Bin; Kim, Hansol; Anderson,Steve; Miller, Jeffrey S; Cichocki, Frank
  3. Journal of immunology (Baltimore, Md. : 1950). 2020, SEP 15; 205(6): 1513-1523.
  1. 8.   New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action
  2. Daidone, Giuseppe; D'Anneo, Antonella; Raimondi, Maria Valeria; Raffa, Demetrio; Hamel,Ernest; Plescia, Fabiana; Lauricella, Marianna; Maggio, Benedetta
  3. Bioorganic chemistry. 2020, AUG; 101: pii: 103989.
  1. 9.   Combination of Trabectedin With Irinotecan, Leucovorin and 5-Fluorouracil Arrests Primary Colorectal Cancer in an Imageable Patient-derived Orthotopic Xenograft Mouse Model
  2. Zhu, Guangwei; Zhao, Ming; Han, Qinghong; Tan, Yuying; Sun, Y U; Bouvet, Michael; Clary, Bryan; Singh,Shree Ram; Ye, Jianxin; Hoffman, Robert M
  3. Anticancer research. 2019, Dec; 39(12): 6463-6470.
  1. 10.   Combination of Trabectedin With Oxaliplatinum and 5-Fluorouracil Arrests a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Zhu, Guangwei; Zhao, Ming; Han, Qinghong; Tan, Yuying; Sun, Y U; Bouvet, Michael; Singh,Shree Ram; Ye, Jianxin; Hoffman, Robert M
  3. Anticancer research. 2019, Nov; 39(11): 5999-6005.
  1. 11.   Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Oshiro, Hiromichi; Tome, Yasunori; Kiyuna, Tasuku; Yoon, Sang Nam; Lwin, Thinzar M; Han, Qinghong; Tan, Yuying; Miyake, Kentaro; Higuchi, Takashi; Sugisawa, Norihiko; Katsuya, Yuki; Park, Jun Ho; Zang, Zhiying; Razmjooei, Sahar; Bouvet, Michael; Clary, Bryan; Singh,Shree Ram; Kanaya, Fuminori; Nishida, Kotaro; Hoffman, Robert M
  3. Anticancer research. 2019, Sep; 39(9): 4667-4671.
  1. 12.   Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents
  2. Morigi, Rita; Locatelli, Alessandra; Leoni, Alberto; Rambaldi, Mirella; Bortolozzi, Roberta; Mattiuzzo, Elena; Ronca, Roberto; Maccarinelli, Federica; Hamel,Ernest; Bai,Ruoli; Brancale, Andrea; Viola, Giampietro
  3. European journal of medicinal chemistry. 2019, MAR 15; 166: 514-530.
  1. 13.   Acetylation of Cytidine in mRNA Promotes Translation Efficiency
  2. Arango, Daniel; Sturgill, David; Alhusaini, Najwa; Dillman, Allissa A.; Sweet, Thomas J.; Hanson, Gavin; Hosogane, Masaki; Sinclair, Wilson R.; Nanan, Kyster K.; Mandler, Mariana D.; Fox,Stephen; Zengeya, Thomas T.; Andresson,Thorkell; Meier,Jordan; Coller, Jeffery; Oberdoerffer, Shalini
  3. CELL. 2018, Dec 13; 175(7): 1872-1886.e24.
  1. 14.   5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox
  2. Müller, Fabian; Cunningham, Tyler; Stookey, Stephanie; Tai, Chin-Hsien; Burkett, Sandra; Jailwala, Parthav; Stetler Stevenson, Maryalice; Cam, Margaret C; Wayne, Alan S; Pastan, Ira
  3. Proceedings of the National Academy of Sciences of the United States of America. 2018, Feb 20; 115(8): E1867-E1875.
  1. 15.   Design, synthesis, and structure-activity relationships of pyrimido[4,5-b]indole-4-amines as microtubule depolymerizing agents that are effective against multidrug resistant cells
  2. Devambatla, Ravi Kumar Vyas; Li, Wei; Zaware, Nilesh; Choudhary, Shruti; Hamel, Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & Medicinal Chemistry Letters. 2017, Aug 01; 27(15): 3423-3430.
  1. 16.   Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression.
  2. Chen, Teresa K; Choi, Michael J; Kao, W H Linda; Astor, Brad C; Scialla, Julia J; Appel, Lawrence J; Li, Liang; Lipkowitz, Michael S; Wolf, Myles; Parekh, Rulan S; Winkler, Cheryl; Estrella, Michelle M; Crews, Deidra C
  3. Clinical journal of the American Society of Nephrology : CJASN. 2015, Dec 7; 10(12): 2128-35.
  1. 17.   Impact of Circulating Vitamin D Binding Protein Levels on the Association between 25-Hydroxyvitamin D and Pancreatic Cancer Risk: A Nested Case-Control Study
  2. Weinstein, S. J.; Stolzenberg-Solomon, R. Z.; Kopp, W.; Rager, H.; Virtamo, J.; Albanes, D.
  3. Cancer Research. 2012, Mar; 72(5): 1190-1198.
  1. 18.   Non-coding rRNA-mediated preferential killing in cancer cells is enhanced by suppression of autophagy in non-transformed counterpart
  2. Hwang, C. J.; Fields, J. R.; Shiao, Y. H.
  3. Cell Death & Disease. 2011, Dec; 2
  1. 19.   The interdomain linker region of HIV-1 capsid protein is a critical determinant of proper core assembly and stability
  2. Jiang, J. Y.; Ablan, S. D.; Derebail, S.; Hercik, K.; Soheilian, F.; Thomas, J. A.; Tang, S. X.; Hewlett, I.; Nagashima, K.; Gorelick, R. J.; Freed, E. O.; Levin, J. G.
  3. Virology. 2011, Dec; 421(2): 253-265.
  1. 20.   Flexible Cullins in Cullin-RING E3 Ligases Allosterically Regulate Ubiquitination
  2. Liu, J.; Nussinov, R.
  3. Journal of Biological Chemistry. 2011, Nov; 286(47): 40934-40942.
  1. 21.   Proline Metabolism and Microenvironmental Stress
  2. Phang, J. M.; Liu, W.; Zabirnyk, O.
  3. Annual review of nutrition. 2010, Aug 21; 30: 441-463.
  1. 22.   The impact of delayed blood centrifuging, choice of collection tube, and type of assay on 25-hydroxyvitamin D concentrations
  2. Yu, C. L.; Falk, R. T.; Kimlin, M. G.; Rajaraman, P.; Sigurdson, A. J.; Horst, R. L.; Cosentino, L. M.; Linet, M. S.; Freedman, D. M.
  3. Cancer Causes & Control. 2010, Apr; 21(4): 643-648.
  1. 23.   Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli
  2. Betham, B.; Shalhout, S.; Marquez, V. E.; Bhagwat, A. S.
  3. DNA Repair. 2010, Feb; 9(2): 153-160.
  1. 24.   Novel approaches to inhibiting HIV-1 replication
  2. Adamson, C. S.; Freed, E. O.
  3. Antiviral Research. 2010, Jan; 85(1): 119-141.
  1. 25.   Highly Efficient Method for C-5 Halogenation of Pyrimidine-Based Nucleosides in Ionic Liquids
  2. Kumar, V.; Yap, J.; Muroyama, A.; Malhotra, S. V.
  3. Synthesis-Stuttgart. 2009, Dec; (23): 3957-3962.
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