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  1. 1.   Bioinformatic analysis linking genomic defects to chemosensitivity and mechanism of action
  2. Covell,David
  3. PloS one. 2021, Apr 28; 16(4):
  1. 2.   Discovery and Optimization of 2H-1 lambda(2)-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer
  2. Rohde, Jason M.; Karavadhi, Surendra; Pragani, Rajan; Liu, Li; Fang, Yuhong; Zhang, Weihe; McIver, Andrew; Zheng, Hongchao; Liu, Qingyang; Davis, Mindy; Urban, Daniel J.; Lee, Tobie D.; Cheff, Dorian M.; Hollingshead,Melinda; Henderson, Mark J.; Martinez, Natalia J.; Brimacombe, Kyle R.; Yasgar, Adam; Zhao, Wei; Klumpp-Thomas, Carleen; Michael, Sam; Covey, Joseph; Moore,Bill; Stott, Gordon M.; Li, Zhuyin; Simeonov, Anton; Jadhav, Ajit; Frye, Stephen; Hall, Matthew D.; Shen, Min; Wang, Xiaodong; Patnaik, Samarjit; Boxer, Matthew B.
  3. Journal of Medicinal Chemistry. 2021, Apr 22; 64(8): 4913-4946.
  1. 3.   CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity
  2. Shrestha, Roshan L.; Rossi, Austin; Wangsa, Darawalee; Hogan, Ann K.; Zaldana, Kimberly S.; Suva, Evelyn; Chung, Yang Jo; Sanders,Chelsea; Difilippantonio,Simone; Karpova, Tatiana S.; Karim,Baktiar; Foltz, Daniel R.; Fachinetti, Daniele; Aplan, Peter D.; Ried, Thomas; Basrai, Munira A.
  3. The Journal of Cell Biology. 2021, Feb 23; 220(4):
  1. 4.   Genomic mapping in outbred mice reveals overlap in genetic susceptibility for HZE ion- and gamma-ray-induced tumors
  2. Edmondson,Elijah; Gatti, D. M.; Ray, F. A.; Garcia, E. L.; Fallgren, C. M.; Kamstock, D. A.; Weil, M. M.
  3. SCIENCE ADVANCES. 2020, Apr; 6(16): eaax5940.
  1. 5.   Antibody-drug conjugates for cancer
  2. Chau, Cindy H.; Steeg,Pat; Figg, William D.
  3. Lancet (London, England). 2019, Aug 31; 394(10200): 793-804.
  1. 6.   IL-15/IL-15R alpha/CD80-expressing AML cell vaccines eradicate minimal residual disease in leukemic mice
  2. Shi, Yimin; Dincheva-Vogel, Lillie; Ayemoba, Charles E.; Fung, Jeffrey P.; Bergamaschi, Cristina; Pavlakis, George; Farzaneh, Farzin; Gaensler, Karin M. L.
  3. BLOOD ADVANCES. 2018, NOV 27; 2(22): 3177-3192.
  1. 7.   PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability
  2. Gryder, Berkley E.; Yohe, Marielle E.; Chou, Hsien-Chao; Zhang, Xiaohu; Marques, Joana; Wachtel, Marco; Schaefer, Beat; Sen, Nirmalya; Song, Young; Gualtieri, Alberto; Pomella, Silvia; Rota, Rossella; Cleveland, Abigail; Wen, Xinyu; Sindiri, Sivasish; Wei, Jun S.; Barr, Frederic G.; Das, Sudipto; Andresson, Thorkell; Guha, Rajarshi; Lal-Nag, Madhu; Ferrer, Marc; Shern, Jack F.; Zhao, Keji; Thomas, Craig J.; Khan, Javed
  3. Cancer Discovery. 2017, Aug; 7(8): 884-899.
  1. 8.   Hematopoiesis and leukemogenesis in mice expressing oncogenic Nras(G12D) from the endogenous locus
  2. Li, Q.; Haigis, K. M.; McDaniel, A.; Harding-Theobald, E.; Kogan, S. C.; Akagi, K.; Wong, J. C. Y.; Braun, B. S.; Wolff, L.; Jacks, T.; Shannon, K.
  3. Blood. 2011, Feb; 117(6): 2022-2032.
  1. 9.   Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
  2. Yap, D. B.; Chu, J.; Berg, T.; Schapira, M.; Cheng, S. W. G.; Moradian, A.; Morin, R. D.; Mungall, A. J.; Meissner, B.; Boyle, M.; Marquez, V. E.; Marra, M. A.; Gascoyne, R. D.; Humphries, R. K.; Arrowsmith, C. H.; Morin, G. B.; Aparicio, S.
  3. Blood. 2011, Feb; 117(8): 2451-2459.
  1. 10.   Genetically modified dendritic cells in cancer immunotherapy: a better tomorrow?
  2. Shurin, M. R.; Gregory, M.; Morris, J. C.; Malyguine, A. M.
  3. Expert Opinion on Biological Therapy. 2010, Nov; 10(11): 1539-1553.
  1. 11.   Identification of Vitronectin as an Extrinsic Inducer of Cancer Stem Cell Differentiation and Tumor Formation
  2. Hurt, E. M.; Chan, K.; Serrat, M. A. D.; Thomas, S. B.; Veenstra, T. D.; Farrar, W. L.
  3. Stem Cells. 2010, Mar 31; 28(3): 390-398.
  1. 12.   Recent Development of Cyclic Amide (Pyridone/Lactam) Moiety Containing Heterocycles as Protein Kinase Inhibitors
  2. Wei, L. Y.; Malhotra, S. V.
  3. Current Medicinal Chemistry. 2010, Jan; 17(3): 234-253.
  1. 13.   Glioblastoma stem cells produce vascular endothelial growth factor by activation of a G-protein coupled formylpeptide receptor FPR
  2. Yao, X. H.; Ping, Y. F.; Chen, J. H.; Xu, C. P.; Chen, D. L.; Zhang, R.; Wang, J. M.; Bian, X. W.
  3. Journal of Pathology. 2008 215(4): 369-376.
  1. 14.   Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma
  2. Yi, L.; Zhou, Z. H.; Ping, Y. F.; Chen, J. H.; Yao, X. H.; Feng, H.; Lu, J. Y.; Wang, J. M.; Bian, X. W.
  3. Modern Pathology. 2007, Oct; 20(10): 1061-1068.
  1. 15.   Cancer stem cells - Redefining the paradigm of cancer treatment strategies
  2. Dean, M.
  3. Molecular Interventions. 2006, Jun; 6(3): 140-148.
  1. 16.   Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis
  2. Du, Y.; Spence, S. E.; Jenkins, N. A.; Copeland, N. G.
  3. Blood. 2005, OCT 1; 106(7): 2498-2505.
  1. 17.   Tumour stem cells and drug resistance
  2. Dean, M.; Fojo, T.; Bates, S.
  3. Nature Reviews Cancer. 2005 5(4): 275-284.
  1. 18.   Role of protein-protein interactions in the antiapoptotic function of EWS-Fli-1
  2. Ramakrishnan, R.; Fujimura, Y.; Zou, J. P.; Liu, F.; Lee, L.; Rao, V. N.; Reddy, E. S. P.
  3. Oncogene. 2004, SEP 16; 23(42): 7087-7094.
  1. 19.   Small molecule toxins targeting tumor receptors
  2. Dyba, M.; Tarasova, N. I.; Michejda, C. J.
  3. Current Pharmaceutical Design. 2004 10(19): 2311-2334.
  1. 20.   Hematopoietic, angiogenic and eye defects in Meis1 mutant animals
  2. Hisa, T.; Spence, S. E.; Rachel, R. A.; Fujita, M.; Nakamura, T.; Ward, J. M.; Devor-Henneman, D. E.; Saiki, Y.; Kutsuna, H.; Tessarollo, L.; Jenkins, N. A.; Copeland, N. G.
  3. Embo Journal. 2004 23(2): 450-459.
  1. 21.   Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein alpha
  2. Miller, M.; Shuman, J. D.; Sebastian, T.; Dauter, Z.; Johnson, P. F.
  3. Journal of Biological Chemistry. 2003 278(17): 15178-15184.
  1. 22.   EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53- mediated trans-activation function
  2. Fujimura, Y.; Siddique, H.; Lee, L.; Rao, V. N.; Reddy, E. S. P.
  3. Oncogene. 2001 20(46): 6653-6659.
  1. 23.   BP1, a new homeobox gene, is frequently expressed in acute leukemias
  2. Haga, S. B.; Fu, S.; Karp, J. E.; Ross, D. D.; Williams, D. M.; Hankins, W. D.; Behm, F.; Ruscetti, F. W.; Chang, M.; Smith, B. D.; Becton, D.; Raimondi, S. C.; Berg, P. E.
  3. Leukemia. 2000 14(11): 1867-1875.
  1. 24.   Transcription-coupled translation control of AML1/RUNX1 is mediated by cap- and internal ribosome entry site-dependent mechanisms
  2. Pozner, A.; Goldenberg, D.; Negreanu, V.; Le, S. Y.; Elroy-Stein, O.; Levanon, D.; Groner, Y.
  3. Molecular and Cellular Biology. 2000 20(7): 2297-2307.
  1. 25.   The ras oncogene-mediated sensitization of human cells to topoisomerase II inhibitor-induced apoptosis
  2. Koo, H. M.; Gray-Goodrich, M.; Kohlhagen, G.; McWilliams, M. J.; Jeffers, M.; Vaigro-Wolff, A.; Alvord, W. G.; Monks, A.; Paull, K. D.; Pommier, Y.; Vande Woude, G. F.
  3. Journal of the National Cancer Institute. 1999 91(3): 236-244.
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