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  1. 1.   Widespread distribution of transcriptionally active, clonally expanded, HIV-1 proviruses despite suppressive antiretroviral therapy
  2. Imamichi, Hiromi; Natarajan,Venkatachala; Scrimieri,Francesca; Smith, Mindy; Badralmaa,Yunden; Bosche,Marjorie; Hensien, Jack M; Buerkert, Thomas; Sherman,Brad; Sherman, Brad T; Singh, Kanal; Lane, H Clifford
  3. The Journal of Clinical Investigation. 2025, Apr 22;
  1. 2.   Divergent populations of HIV-infected naïve and memory CD4+ T-cell clones in children on antiretroviral therapy
  2. Katusiime, Mary Grace; Neer,Victoria; Guo, Shuang; Patro,Sean; Wang,Wenjie; Luke,Brian; Capoferri,Adam; Wu,Xiaolin; Horner, Anna M; Rausch,Jason; Chahroudi, Ann; Mavigner, Maud; Kearney,Mary
  3. The Journal of Clinical Investigation. 2025, Mar 06;
  1. 3.   Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection
  2. Happe, Myra; Lynch, Rebecca M; Fichtenbaum, Carl J; Heath, Sonya L; Koletar, Susan L; Landovitz, Raphael J; Presti, Rachel M; Santana-Bagur, Jorge L; Tressler, Randall L; Holman, LaSonji A; Novik, Laura; Roa, Jhoanna C; Rothwell, Ro Shauna; Strom, Larisa; Wang,Jing; Hu, Zonghui; Conan-Cibotti, Michelle; Bhatnagar, Anjali M; Dwyer, Bridget; Ko, Sung Hee; Belinky, Frida; Namboodiri, Aryan M; Pandey, Janardan P; Carroll, Robin; Basappa, Manjula; Serebryannyy, Leonid; Narpala, Sandeep R; Lin, Bob C; McDermott, Adrian B; Boritz, Eli A; Capparelli, Edmund V; Coates, Emily E; Koup, Richard A; Ledgerwood, Julie E; Mascola, John R; Chen, Grace L; Tebas, Pablo
  3. JCI Insight. 2025, Feb 24; 10(4):
  1. 4.   Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys
  2. Raehtz, Kevin D; Xu, Cuiling; Deleage,Claire; Ma, Dongzhu; Policicchio, Benjamin B; Brocca-Cofano, Egidio; Piccolo, Daniele; Weaver, Kathryn; Keele,Brandon; Estes, Jacob D; Apetrei, Cristian; Pandrea, Ivona
  3. JCI Insight. 2024, Dec 06; 9(23):
  1. 5.   Focusing HIV-1 Gag T-cell Responses to Highly Conserved Regions by DNA Vaccination in HVTN 119
  2. Kalams, Spyros A; Felber,Barbara; Mullins, James I; Scott, Hyman M; Allen, Mary A; De Rosa, Stephen C; Heptinstall, Jack; Tomaras, Georgia D; Hu, Jiani; deCamp, Allan C; Rosati,Margherita; Bear,Jenifer; Pensiero, Michael N; Eldridge, John; Egan, Michael A; Hannaman, Drew; McElrath, M Juliana; Pavlakis,George
  3. JCI Insight. 2024, Aug 01;
  1. 6.   Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of Simian immunodeficiency virus
  2. Simpson, Jennifer; Starke, Carly E; Ortiz, Alexandra M; Ransier, Amy; Darko, Sam; Llewellyn-Lacey, Sian; Fennessey,Christine; Keele,Brandon; Douek, Daniel C; Price, David A; Brenchley, Jason M
  3. JCI Insight. 2024, Jun 11;
  1. 7.   Innate protection against intrarectal SIV acquisition by a live SHIV vaccine
  2. Sui, Yongjun; Meyer, Thomas J; Fennessey,Christine; Keele,Brandon; Dadkhah,Kimia; Ma, Chi; LaBranche, Celia C; Breed, Matthew W; Kramer,Josh; Li, Jianping; Howe, Savannah E; Ferrari, Guido; Williams, LaTonya D; Cam, Maggie; Kelly,Michael; Shen, Xiaoying; Tomaras, Georgia D; Montefiori, David; Greten, Tim F; Miller, Christopher J; Berzofsky, Jay A
  3. JCI Insight. 2024, May 21; 9(12):
  1. 8.   Clonal hematopoiesis in people with advanced HIV and associated inflammatory syndromes
  2. Rocco, Joseph M; Zhou, Yifan; Liu, Nicholas S; Laidlaw, Elizabeth; Galindo, Frances; Anderson, Megan V; Rupert,Adam; Lucena Lage, Silvia; Ortega-Villa, Ana M; Yu, Shiqin; Lisco, Andrea; Manion, Maura; Vassiliou, George S; Dunbar, Cynthia E; Sereti, Irini
  3. JCI Insight. 2024, Apr 02; 9(9):
  1. 9.   Chronic SIV-induced neuroinflammation disrupts CCR7+CD4+ T cell immunosurveillance in the rhesus macaque brain
  2. Elizaldi, Sonny R; Hawes, Chase E; Verma, Anil; Shaan Lakshmanappa, Yashavanth; Dinasarapu, Ashok R; Schlegel, Brent T; Rajasundaram, Dhivyaa; Li, Jie; Durbin-Johnson, Blythe P; Ma, Zhong-Min; Pal, Pabitra B; Beckman, Danielle; Ott, Sean; Raeman, Reben; Lifson,Jeffrey; Morrison, John H; Iyer, Smita S
  3. The Journal of Clinical Investigation. 2024, Mar 12; 134(9):
  1. 10.   Comprehensive analysis of HIV reservoirs in elite controllers
  2. Kennedy, Brooke D; Blazkova, Jana; Justement, Jesse S; Shi, Victoria; Rai, M Ali; Manning, Maegan R; Praiss, Lauren; Gittens, Kathleen; Wender, Paul A; Patro,Sean; Wu,Xiaolin; Moir, Susan; Chun, Tae-Wook
  3. The Journal of Clinical Investigation. 2023, Feb 01; 133(3): e165446.
  1. 11.   Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy
  2. Varco-Merth, Benjamin D; Brantley, William; Marenco, Alejandra; Duell, Derick D; Fachko, Devin N; Richardson, Brian; Busman-Sahay, Kathleen; Shao, Danica; Flores, Walter; Engelman, Kathleen; Fukazawa, Yoshinori; Wong, Scott W; Skalsky, Rebecca L; Smedley, Jeremy; Axthelm, Michael K; Lifson,Jeffrey; Estes, Jacob D; Edlefsen, Paul T; Picker, Louis; Cameron, Cheryl Ma; Henrich, Timothy J; Okoye, Afam A
  3. The Journal of Clinical Investigation. 2022, Mar 22;
  1. 12.   Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
  2. Harper, Justin; Ribeiro, Susan P; Chan, Chi Ngai; Aid, Malika; Deleage,Claire; Micci, Luca; Pino, Maria; Cervasi, Barbara; Raghunathan, Gopalan; Rimmer, Eric; Ayanoglu, Gulesi; Wu, Guoxin; Shenvi, Neeta; Barnard, Richard Jo; Del Prete,Greg; Busman-Sahay, Kathleen; Silvestri, Guido; Kulpa, Deanna A; Bosinger, Steven E; Easley, Kirk; Howell, Bonnie J; Gorman, Dan; Hazuda, Daria J; Estes, Jacob D; Sekaly, Rafick-Pierre; Paiardini, Mirko
  3. The Journal of Clinical Investigation. 2022, Mar 01; 132(8):
  1. 13.   IFNa-blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health
  2. Swainson, Louise A; Sharma, Ashish Arunkumar; Ghneim, Khader; Ribeiro, Susan Pereira; Wilkinson, Peter; Dunham, Richard M; Albright, Rebecca G; Wong, Samson; Estes, Jacob D; Piatak, Michael; Deeks, Steven G; Hunt, Peter W; Sekaly, Rafick-Pierre; McCune, Joseph M
  3. JCI Insight. 2022, Feb 01;
  1. 14.   Concordance of immunological events between intrarectal and intravenous SHIVAD8-EO infection when assessed by Fiebig-equivalent staging
  2. Dias, Joana; Fabozzi, Giulia; March, Kylie; Asokan, Mangaiarkarasi; Almasri, Cassandra G; Fintzi, Jonathan; Promsote, Wanwisa; Nishimura, Yoshiaki; Todd, John-Paul; Lifson,Jeffrey; Martin, Malcolm A; Gama, Lucio; Petrovas, Constantinos; Pegu, Amarendra; Mascola, John R; Koup, Richard A
  3. The Journal of clinical investigation. 2021, Sep 01; 131(17):
  1. 15.   CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification
  2. Okoye, Afam A; Duell, Derick D; Fukazawa, Yoshinori; Varco-Merth, Benjamin; Marenco, Alejandra; Behrens, Hannah; Chaunzwa, Talent Morgan; Selseth, Andrea N; Gilbride, Roxanne M; Shao, Jason; Edlefsen, Paul T; Geleziunas, Romas; Pinkevych, Mykola; Davenport, Miles P; Busman-Sahay, Kathleen; Nekorchuk, Michael D; Park, Haesun; Smedley, Jeremy V; Axthelm, Michael K; Estes, Jacob D; Hansen, Scott G; Keele,Brandon; Lifson,Jeffrey; Picker, Louis J
  3. The Journal of clinical investigation. 2021, Apr 15; 131(8):
  1. 16.   HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus
  2. Halvas, Elias K; Joseph, Kevin W; Brandt, Leah D; Guo,Amber; Sobolewski, Michele D; Jacobs, Jana L; Tumiotto, Camille; Bui, John K; Cyktor, Joshua C; Keele,Brandon; Morse, Gene D; Bale, Michael J; Shao,Wei; Kearney,Mary; Coffin, John M; Rausch,Jason; Wu,Xiaolin; Hughes,Stephen; Mellors, John W
  3. The Journal of clinical investigation. 2020, NOV 2; 130(11): 5847-5857.
  1. 17.   HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy
  2. McManus, William R; Bale, Michael J; Spindler,Jon; Wiegand,Ann; Musick,Andrew; Patro,Sean; Sobolewski, Michele D; Musick, Victoria K; Anderson, Elizabeth M; Cyktor, Joshua C; Halvas, Elias K; Shao,Wei; Wells,Daria; Wu,Xiaolin; Keele,Brandon; Milush, Jeffrey M; Hoh, Rebecca; Mellors, John W; Hughes,Stephen; Deeks, Steven G; Coffin, John M; Kearney,Mary
  3. The Journal of clinical investigation. 2019, Nov 1; 129(11): 4629-4642.
  1. 18.   Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir
  2. Yu, Wen-Han; Su, David; Torabi, Julia; Fennessey,Christine; Shiakolas, Andrea; Lynch, Rebecca; Chun, Tae-Wook; Doria-Rose, Nicole; Alter, Galit; Seaman, Michael S; Keele,Brandon; Lauffenburger, Douglas A; Julg, Boris
  3. JCI insight. 2019, Sep 05; 4(17): pii: 130153.
  1. 19.   Clones of infected cells arise early in HIV-infected individuals
  2. Coffin, John M; Wells, David W; Zerbato, Jennifer M; Kuruc, Joann D; Guo, Shuang; Luke,Brian; Eron, Joseph J; Bale,Michael; Spindler,Jon; Simonetti, Francesco R; Hill,Shawn; Kearney,Mary; Maldarelli,Frank; Wu, Xiaolin; Mellors, John W; Hughes,Stephen
  3. JCI insight. 2019, Jun 20; 4(12): pii: 128432. .
  1. 20.   TLR7 agonist administration to SIV-infected macaques receiving early initiated cART does not induce plasma viremia
  2. Del Prete,Greg; Alvord, W Gregory; Li,Yuan; Deleage,Claire; Nag,Mukta; Oswald,Kelli; Thomas,James; Pyle,Cathi; Bosche,Bj; Coalter,Vicky; Wiles,Adam; Wiles,Rodney; Berkemeier,Brian; Hull,Mike; Chipriano, Elizabeth; Silipino,Lorna; Fast,Randy; Kiser,Jacob; Kiser,Rebecca; Malys,Tyler; Kramer,Josh; Breed,Matthew; Trubey,Charles; Estes,Jake; Barnes, Tiffany L; Hesselgesser, Joseph; Geleziunas, Romas; Lifson,Jeffrey
  3. JCI insight. 2019, Jun 06; 4(11): pii: 127717.
  1. 21.   Combination anti-PD-1 and antiretroviral therapy provides therapeutic benefit against SIV
  2. Mylvaganam, Geetha H; Chea, Lynette S; Tharp, Gregory K; Hicks, Sakeenah; Velu, Vijayakumar; Iyer, Smita S; Deleage, Claire; Estes, Jake; Bosinger, Steven E; Freeman, Gordon J; Ahmed, Rafi; Amara, Rama R
  3. JCI insight. 2018, Sep 20; 3(18): pii: 122940.
  1. 22.   Total body CD4+ T cell dynamics in treated and untreated SIV infection revealed by in vivo imaging
  2. Di Mascio, Michele; Srinivasula, Sharat; Kim, Insook; Duralde, Gorka; St Claire, Alexis; DeGrange, Paula; St Claire, Marisa; Reimann, Keith A; Gabriel, Erin E; Carrasquillo, Jorge; Reba, Richard C; Paik, Chang; Lane, Henry C
  3. JCI Insight. 2018, Jul 12; 3(13): pii: 97880.
  1. 23.   Accumulation of follicular CD8+ T cells in pathogenic SIV infection
  2. Ferrando-Martinez, Sara; Moysi, Eirini; Pegu, Amarendra; Andrews, Sarah; Nganou Makamdop, Krystelle; Ambrozak, David; McDermott, Adrian B; Palesch, David; Paiardini, Mirko; Pavlakis, George; Brenchley, Jason M; Douek, Daniel; Mascola, John R; Petrovas, Constantinos; Koup, Richard A
  3. The Journal of Clinical Investigation. 2018, May 01; 128(5): 2089-2103.
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