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  1. 1.   HSF1 physically neutralizes amyloid oligomers to empower overgrowth and bestow neuroprotection
  2. Tang,Zijian; Su,Kuo-Hui; Xu, Meng; Dai,Chengkai
  3. Science advances. 2020, Nov; 6(46): pii: eabc6871.
  1. 2.   Medin Oligomer Membrane Pore Formation: A Potential Mechanism of Vascular Dysfunction
  2. Younger, Scott; Jang,Hyunbum; Davies, Hannah A; Niemiec, Martin J; Garcia, Joe G N; Nussinov,Ruth; Migrino, Raymond Q; Madine, Jillian; Arce, Fernando T
  3. Biophysical journal. 2020, JUN 2; 118(11): 2769-2782.
  1. 3.   Estimating associations between antidepressant use and incident mild cognitive impairment in older adults with depression
  2. Han, Fang; Bonnett,Tyler; Brenowitz, Willa D; Teylan, Merilee A; Besser, Lilah M; Chen, Yen-Chi; Chan, Gary; Cao, Ke-Gang; Gao, Ying; Zhou, Xiao-Hua
  3. PloS one. 2020, JAN 17; 15(1): e0227924.
  1. 4.   deepDR: A network-based deep learning approach to in silico drug repositioning
  2. Zeng, Xiangxiang; Zhu, Siyi; Liu, Xiangrong; Zhou, Yadi; Nussinov,Ruth; Cheng, Feixiong
  3. Bioinformatics (Oxford, England). 2019, DEC 15; 35(24): 5191-5198.
  1. 5.   Antimicrobial Properties of Amyloid Peptides
  2. Kagan, B. L.; Jang, H.; Capone, R.; Arce, F. T.; Ramachandran, S.; Lal, R.; Nussinov, R.
  3. Molecular Pharmaceutics. 2012, Apr; 9(4): 708-717.
  1. 6.   All-D-Enantiomer of beta-Amyloid Peptide Forms Ion Channels in Lipid Bilayers
  2. Capone, R.; Jang, H.; Kotler, S. A.; Connelly, L.; Arce, F. T.; Ramachandran, S.; Kagan, B. L.; Nussinov, R.; Lal, R.
  3. Journal of Chemical Theory and Computation. 2012, Mar; 8(3): 1143-1152.
  1. 7.   CCAAT/enhancer binding protein delta (CEBPD) elevating PTX3 expression inhibits macrophage-mediated phagocytosis of dying neuron cells
  2. Ko, C. Y.; Chang, L. H.; Lee, Y. C.; Sterneck, E.; Cheng, C. P.; Chen, S. H.; Huang, A. M.; Tseng, J. T.; Wang, J. M.
  3. Neurobiology of Aging. 2012, Feb; 33(2):
  1. 8.   Polymorphism of amyloid beta peptide in different environments: implications for membrane insertion and pore formation
  2. Arce, F. T.; Jang, H. B.; Ramachandran, S.; Landon, P. B.; Nussinov, R.; Lal, R.
  3. Soft Matter. 2011, Jun 7; 7(11): 5267-5273.
  1. 9.   Synergistic Interactions between Repeats in Tau Protein and A beta Amyloids May Be Responsible for Accelerated Aggregation via Polymorphic States
  2. Miller, Y.; Ma, B. Y.; Nussinov, R.
  3. Biochemistry. 2011, Jun; 50(23): 5172-5181.
  1. 10.   Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People
  2. McKay, G. J.; Silvestri, G.; Chakravarthy, U.; Dasari, S.; Fritsche, L. G.; Weber, B. H.; Keilhauer, C. N.; Klein, M. L.; Francis, P. J.; Klaver, C. C.; Vingerling, J. R.; Ho, L.; De Jong, P.; Dean, M.; Sawitzke, J.; Baird, P. N.; Guymer, R. H.; Stambolian, D.; Orlin, A.; Seddon, J. M.; Peter, I.; Wright, A. F.; Hayward, C.; Lotery, A. J.; Ennis, S.; Gorin, M. B.; Weeks, D. E.; Kuo, C. L.; Hingorani, A. D.; Sofat, R.; Cipriani, V.; Swaroop, A.; Othman, M.; Kanda, A.; Chen, W.; Abecasis, G. R.; Yates, J. R.; Webster, A. R.; Moore, A. T.; Seland, J. H.; Rahu, M.; Soubrane, G.; Tomazzoli, L.; Topouzis, F.; Vioque, J.; Young, I. S.; Fletcher, A. E.; Patterson, C. C.
  3. American Journal of Epidemiology. 2011, Jun; 173(12): 1357-1364.
  1. 11.   Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link
  2. Jang, H. J. H.; Arce, F. T.; Mustata, M.; Ramachandran, S.; Capone, R.; Nussinov, R.; Lal, R.
  3. Biophysical Journal. 2011, Apr; 100(7): 1775-1783.
  1. 12.   Combinatorial Tau Pseudophosphorylation MARKEDLY DIFFERENT REGULATORY EFFECTS ON MICROTUBULE ASSEMBLY AND DYNAMIC INSTABILITY THAN THE SUM OF THE INDIVIDUAL PARTS
  2. Kiris, E.; Ventimiglia, D.; Sargin, M. E.; Gaylord, M. R.; Altinok, A.; Rose, K.; Manjunath, B. S.; Jordan, M. A.; Wilson, L.; Feinstein, S. C.
  3. Journal of Biological Chemistry. 2011, Apr; 286(16): 14257-14270.
  1. 13.   In Glaucoma the Upregulated Truncated TrkC.T1 Receptor Isoform in Glia Causes Increased TNF-alpha Production, Leading to Retinal Ganglion Cell Death
  2. Bai, Y. J.; Shi, Z. H.; Zhuo, Y. H.; Liu, J.; Malakhov, A.; Ko, E.; Burgess, K.; Schaefer, H.; Esteban, P. F.; Tessarollo, L.; Saragovi, H. U.
  3. Investigative Ophthalmology & Visual Science. 2010, Dec; 51(12): 6639-6651.
  1. 14.   Resveratrol differentially modulates inflammatory responses of microglia and astrocytes
  2. Lu, X. F.; Ma, L. L.; Ruan, L. F.; Kong, Y.; Mou, H. W.; Zhang, Z. J.; Wang, Z. J.; Wang, J. M.; Le, Y. Y.
  3. Journal of Neuroinflammation. 2010, Aug; 7: 14.
  1. 15.   Structural Convergence Among Diverse, Toxic beta-Sheet Ion Channels
  2. Jang, H.; Arce, F. T.; Ramachandran, S.; Capone, R.; Lal, R.; Nussinov, R.
  3. Journal of Physical Chemistry B. 2010, Jul 29; 114(29): 9445-9451.
  1. 16.   Antimicrobial Protegrin-1 Forms Ion Channels: Molecular Dynamic Simulation, Atomic Force Microscopy, and Electrical Conductance Studies
  2. Capone, R.; Mustata, M.; Jang, H.; Arce, F. T.; Nussinov, R.; Lal, R.
  3. Biophysical Journal. 2010, Jun; 98(11): 2644-2652.
  1. 17.   Quantitative Analysis of MAP-Mediated Regulation of Microtubule Dynamic Instability In Vitro-Focus on Tau
  2. Kiris, E.; Ventimiglia, D.; Feinstein, S. C.
  3. Methods in cell biology. 2010; 95 : 481-503.
  1. 18.   Atomic-Scale Simulations Confirm that Soluble beta-Sheet-Rich Peptide Self-Assemblies Provide Amyloid Mimics Presenting Similar Conformational Properties
  2. Yu, X.; Wang, J. D.; Yang, J. C.; Wang, Q. M.; Cheng, S. Z. D.; Nussinov, R.; Zheng, J.
  3. Biophysical Journal. 2010, Jan; 98(1): 27-36.
  1. 19.   Various drug delivery approaches to the central nervous system
  2. Pasha, S.; Gupta, K.
  3. Expert Opinion on Drug Delivery. 2010, Jan; 7(1): 113-135.
  1. 20.   Synergy of TRIF-dependent TLR3 and MyD88-dependent TLR7 in up-regulating expression of mouse FPR2, a promiscuous G-protein-coupled receptor, in microglial cells
  2. Chen, K. Q.; Huang, J.; Liu, Y.; Gong, W. H.; Cui, Y. H.; Wang, J. M.
  3. Journal of Neuroimmunology. 2009 213(1-2): 69-77.
  1. 21.   K3 Fragment of Amyloidogenic beta(2)-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis
  2. Mustata, M.; Capone, R.; Jang, H.; Arce, F. T.; Ramachandran, S.; Lal, R.; Nussinov, R.
  3. Journal of the American Chemical Society. 2009 131(41): 14938-14945.
  1. 22.   New structures help the modeling of toxic amyloid beta ion channels
  2. Jang, H. B.; Zheng, J.; Lal, R.; Nussinov, R.
  3. Trends in Biochemical Sciences. 2008 33(2): 91-100.
  1. 23.   The big brain aquaporin is required for endosome maturation and notch receptor trafficking
  2. Kanwar, R.; Fortini, M. E.
  3. Cell. 2008 133(5): 852-863.
  1. 24.   Role for nanomaterial-autophagy interaction in neurodegenerative disease
  2. Stern, S. T.; Johnson, D. N.
  3. Autophagy. 2008 4(8): 1097-1100.
  1. 25.   Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process
  2. Jang, H.; Zheng, J.; Nussinov, R.
  3. Biophysical Journal. 2007, Sep; 93(6): 1938-1949.
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