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  1. 1.   Deciphering the chemical instability of sphaeropsidin A under physiological conditions - degradation studies and structural elucidation of the major metabolite
  2. van der Westhuyzen, Alet E; Ingels, Aude; Rosière, Rémi; Amighi, Karim; Oberer, Lukas; Gustafson,Kirk; Wang,Dongdong; Evidente, Antonio; Maddau, Lucia; Masi, Marco; de Villiers, André; Green, Ivan R; Berger, Walter; Kornienko, Alexander; Mathieu, Veronique; van Otterlo, Willem A L
  3. Organic & biomolecular chemistry. 2020, OCT 28; 18(40): 8147-8160.
  1. 2.   Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors
  2. Kazan, Fusun; Yagci, Z Begum; Bai,Ruoli; Ozkirimli, Elif; Hamel,Ernest; Ozkirimli, Sumru
  3. Computational biology and chemistry. 2019, Jun; 80: 512-523.
  1. 3.   Synthesis and Biological Evaluation of New Madecassic Acid Derivatives Targeting ERK Cascade Signaling
  2. Valdeira, Ana S C; Ritt,Daniel; Morrison,Deborah; McMahon, James B; Gustafson, Kirk R; Salvador, Jorge A R
  3. Frontiers in chemistry. 2018, Sep 28; 6: 434.
  1. 4.   Antineoplastic Agents. 548. Synthesis of lodo- and Diiodocombstatin Phosphate Prodrugs
  2. Pettit, G. R.; Rosenberg, H. J.; Dixon, R.; Knight, J. C.; Hamel, E.; Chapuis, J. C.; Pettit, R. K.; Hogan, F.; Sumner, B.; Ain, K. B.; Trickey-Platt, B.
  3. Journal of Natural Products. 2012, Mar; 75(3): 385-393.
  1. 5.   Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors
  2. Leese, M. P.; Jourdan, F.; Dohle, W.; Kimberley, M. R.; Thomas, M. P.; Bai, R. L.; Hamel, E.; Ferrandis, E.; Potter, B. V. L.
  3. Acs Medicinal Chemistry Letters. 2012, Jan; 3(1): 5-9.
  1. 6.   Synthesis, Antitubulin, and Antiproliferative SAR of Analogues of 2-Methoxyestradiol-3,17-O,O-bis-sulfamate
  2. Jourdan, F.; Leese, M. P.; Dohle, W.; Hamel, E.; Ferrandis, E.; Newman, S. P.; Purohit, A.; Reed, M. J.; Potter, B. V. L.
  3. Journal of Medicinal Chemistry. 2010, Apr; 53(7): 2942-2951.
  1. 7.   Evaluation of indenoisoquinoline topoisomerase I inhibitors using a hollow fiber assay
  2. Morrell, A.; Jayaraman, M.; Nagarajan, M.; Fox, B. M.; Meckley, M. R.; Ioanoviciu, A.; Pommier, Y.; Antony, S.; Hollineshead, M.; Cushman, M.
  3. Bioorganic & Medicinal Chemistry Letters. 2006, Aug; 16(16): 4395-4399.
  1. 8.   Inositol hexaphosphate (IP6) blocks proliferation of human breast cancer cells through a PKC delta-dependent increase in p27(Kip1) and decrease in retinoblastoma protein (pRb) phosphorylation
  2. Vucenik, I.; Ramakrishna, G.; Tantivejkul, K.; Anderson, L. M.; Ramljak, D.
  3. Breast Cancer Research and Treatment. 2005, MAY; 91(1): 35-45.
  1. 9.   The antitumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces NF-kappa B activity in drug-sensitive MCF-7 cells
  2. Brantley, E.; Patel, V.; Stinson, S. F.; Trapani, V.; Hose, C. D.; Ciolino, H. P.; Yeh, G. C.; Gutkind, J. S.; Sausville, E. A.; Loaiza-Perez, A. I.
  3. Anti-Cancer Drugs. 2005, FEB; 16(2): 137-143.
  1. 10.   Anticancer metal compounds in NCI's tumor-screening database: putative mode of action
  2. Huang, R. L.; Wallqvist, A.; Covell, D. G.
  3. Biochemical Pharmacology. 2005 69(7): 1009-1039.
  1. 11.   A tale of two tumor targets: Topoisomerase I and tubulin. The Wall and Wani contribution to cancer chemotherapy
  2. Cragg, G. M.; Newman, D. J.
  3. Journal of Natural Products. 2004 67(2): 232-244.
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