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  1. 2.   IKK alpha represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin
  2. Liu, B.; Willette-Brown, J.; Liu, S.; Chen, X.; Fischer, S. M.; Hu, Y.
  3. Cell Death and Differentiation. 2011, Dec; 18(12): 1854-1864.
  1. 3.   Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii
  2. Diyabalanage, T.; Ratnayake, R.; Wilson, J. A.; Henrich, C. J.; Beutler, J. A.; Colburn, N. H.; McMahon, J. B.; Gustafson, K. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2011, Aug; 21(15): 4397-4399.
  1. 4.   Grassypeptolides F and G, Cyanobacterial Peptides from Lyngbya majuscula
  2. Popplewell, W. L.; Ratnayake, R.; Wilson, J. A.; Beutler, J. A.; Colburn, N. H.; Henrich, C. J.; McMahon, J. B.; McKee, T. C.
  3. Journal of Natural Products. 2011, Aug; 74(8): 1686-1691.
  1. 5.   A Dominant-Negative c-jun Mutant Inhibits Lung Carcinogenesis in Mice
  2. Tichelaar, J. W.; Yan, Y.; Tan, Q.; Wang, Y. A.; Estensen, R. D.; Young, M. R.; Colburn, N. H.; Yin, H. L.; Goodin, C.; Anderson, M. W.; You, M.
  3. Cancer Prevention Research. 2010, Sep; 3(9): 1148-1156.
  1. 6.   Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion
  2. Santhanam, A. N.; Baker, A. R.; Hegamyer, G.; Kirschmann, D. A.; Colburn, N. H.
  3. Oncogene. 2010, Jul; 29(27): 3921-3932.
  1. 7.   Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition
  2. Beutler, J. A.; Kang, M. I.; Robert, F.; Clement, J. A.; Pelletier, J.; Colburn, N. H.; McKee, T. C.; Goncharova, E.; McMahon, J. B.; Henrich, C. J.
  3. Journal of Natural Products. 2009, Mar 27; 72(3): 503-6.
  1. 8.   A selective small-molecule nuclear factor-kappa B inhibitor from a high-throughput cell-based assay for "activator protein-1 hits"
  2. Kang, M. I.; Henrich, C. J.; Bokesch, H. R.; Gustafson, K. R.; McMahon, J. B.; Baker, A. R.; Young, M. R.; Colburn, N. H.
  3. Molecular Cancer Therapeutics. 2009 8(3): 571-581.
  1. 9.   Linoleic acid metabolite suppresses skin inflammation and tumor promotion in mice: possible roles of programmed cell death 4 induction
  2. Yasuda, M.; Nishizawa, T.; Ohigashi, H.; Tanaka, T.; Hou, D. X.; Colburn, N. H.; Murakami, A.
  3. Carcinogenesis. 2009 30(7): 1209-1216.
  1. 10.   JNK/AP-1 pathway is involved in tumor necrosis factor-alpha induced expression of vascular endothelial growth factor in MCF7 cells
  2. Yin, Y. M.; Wang, S.; Sun, Y. J.; Matt, Y.; Colburn, N. H.; Shu, Y. Q.; Han, X.
  3. Biomedicine and Pharmacotherapy. 2009 63(6): 429-435.
  1. 11.   Targeting Transcription Factors for Cancer Prevention-the Case of Nrf2
  2. Colburn, N. H.; Kensler, T. W.
  3. Cancer Prevention Research. 2008 1(3): 153-155.
  1. 12.   Targeting the Activator Protein 1 Transcription Factor for the Prevention of Estrogen Receptor-Negative Mammary Tumors
  2. Shen, Q.; Uray, I. P.; Li, Y. X.; Zhang, Y.; Hill, J.; Xu, X. C.; Young, M. R.; Gunther, E. J.; Hilsenbeck, S. G.; Colburn, N. H.; Chodosh, L. A.; Brown, P. H.
  3. Cancer Prevention Research. 2008 1(1): 45-55.
  1. 13.   Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors
  2. Leupold, J. H.; Yang, H. S.; Colburn, N. H.; Asangani, I.; Post, S.; Allgayer, H.
  3. Oncogene. 2007, Jul; 26(31): 4550-4562.
  1. 14.   A high-throughput cell-based assay to identify specific inhibitors of transcription factor AP-1
  2. Ruocco, K. M.; Goncharova, E. I.; Young, M. R.; Colburn, N. H.; McMahon, J. B.; Henrich, C. J.
  3. Journal of Biomolecular Screening. 2007, Feb; 12(1): 133-139.
  1. 15.   Fra-1 a target for cancer prevention or intervention
  2. Young, M. R.; Colburn, N. H.
  3. Gene. 2006, Sep; 379: 1-11.
  1. 16.   Prevention of human papilloma virus (HPV) E7-driven tumorigenesis by dominant negative AP-1 (TAM67) appears to be mediated by Cox-2 repression
  2. Matthews, C. P.; Young, M. R.; Colburn, N. H.
  3. Cancer Epidemiology Biomarkers & Prevention. 2005, NOV; 14(11, Part 2 Suppl. S): 2748S-2749S.
  1. 17.   AP-1 blockade in vivo suppresses development of mammary tumor in MMTV-erbB2 mice
  2. Shen, Q.; Kim, H. T.; Young, M.; Gunther, E.; Hilsenbeck, S.; Chodosh, L.; Colburn, N.; Brown, P.
  3. Cancer Epidemiology Biomarkers & Prevention. 2005, NOV; 14(11, Part 2 Suppl. S): 2692S-2692S.
  1. 18.   Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity
  2. Kong, D. H.; Park, E. J.; Stephen, A. G.; Calvani, M.; Cardellina, J. H.; Monks, A.; Fisher, R. J.; Shoemaker, R. H.; Melillo, G.
  3. Cancer Research. 2005, OCT 1; 65(19): 9047-9055.
  1. 19.   A high-throughput fluorescence-anisotropy screen that identifies small molecule inhibitors of the DNA binding of B-ZIP transcription factors
  2. Rishi, V.; Potter, T.; Laudeman, J.; Reinhart, R.; Silvers, T.; Selby, M.; Stevenson, T.; Krosky, P.; Stephen, A. G.; Acharya, A.; Moll, J.; Oh, W. J.; Scudiero, D.; Shoemaker, R. H.; Vinson, C.
  3. Analytical Biochemistry. 2005, MAY 15; 340(2): 259-271.
  1. 20.   Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as immune adjuvant
  2. Kurosaka, K.; Chen, Q.; Yarovinsky, F.; Oppenheim, J. J.; Yang, D.
  3. Journal of Immunology. 2005, MAY 15; 174(10): 6257-6265.
  1. 21.   A paracrine signal mediates the cell transformation response to low dose gamma radiation in JB6 cells
  2. Weber, T. J.; Siegel, R. W.; Markille, L. M.; Chrisler, W. B.; Lei, X. Y. C.; Colburn, N. H.
  3. Molecular Carcinogenesis. 2005, MAY; 43(1): 31-37.
  1. 22.   Cadmium-induced malignant transformation in rat liver cells: role of aberrant oncogene expression and minimal role of oxidative stress
  2. Qu, W.; Diwan, B. A.; Reece, J. M.; Bortner, C. D.; Pi, J. B.; Liu, J.; Waalkes, M. P.
  3. International Journal of Cancer. 2005, APR 10; 114(3): 346-355.
  1. 23.   Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI
  2. Zakowicz, H.; Yang, H. S.; Stark, C.; Wlodawer, A.; Laronde-Leblanc, N.; Colburn, N. H.
  3. Rna-a Publication of the Rna Society. 2005, MAR; 11(3): 261-274.
  1. 24.   Heterodimer formation between c-Jun and Jun B proteins mediated by Epstein Barr virus encoded latent membrane protein 1
  2. Song, X.; Tao, Y. G.; Tan, Y. N.; Lee, L. M.; Deng, X. Y.; Wu, Q.; Cao, Y.
  3. Science in China Series C-Life Sciences. 2005, FEB; 48(1): 70-80.
  1. 25.   Inhibition of human neutrophil IL-8 production by hydrogen peroxide and dysregulation in chronic granulomatous disease
  2. Lekstrom-Himes, J. A.; Kuhns, D. B.; Alvord, W. G.; Gallin, J. I.
  3. Journal of Immunology. 2005, JAN 1; 174(1): 411-417.
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