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  1. 1.   TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells
  2. Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett,Stephen; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley
  3. Cancer Letters. 2025, Jun 28; 620: 217692.
  1. 2.   IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis
  2. Starkey, Malcolm R; Plank, Maximilian W; Casolari, Paolo; Papi, Alberto; Pavlidis, Stelios; Guo, Yike; Cameron, Guy J M; Haw, Tatt Jhong; Tam, Anthony; Obiedat, Ma'en; Donovan, Chantal; Hansbro, Nicole G; Nguyen, Duc H; Nair, Prema Mono; Kim, Richard Y; Horvat, Jay C; Kaiko, Gerard E; Durum,Scott; Wark, Peter A; Sin, Don D; Caramori, Gaetano; Adcock, Ian M; Foster, Paul S; Hansbro, Philip M
  3. The European respiratory journal. 2019, JUL 1; 54(1): pii: 1800174..
  1. 3.   Optimized combination therapy using bortezomib, TRAIL and TLR agonists in established breast tumors
  2. Lee, S.; Yagita, H.; Sayers, T. J.; Celis, E.
  3. Cancer Immunology Immunotherapy. 2010, Jul; 59(7): 1073-1081.
  1. 4.   Identification and characterization of a novel agonistic anti-DR4 human monoclonal antibody
  2. Feng, Y.; Xiao, X. D.; Zhu, Z. Y.; Dimitrov, D. S.
  3. Mabs. 2010, Sep-Oct; 2(5): 565-570.
  1. 5.   Application of tissue-specific NK and NKT cell activity for tumor immunotherapy
  2. Subleski, J. J.; Wiltrout, R. H.; Weiss, J. M.
  3. Journal of Autoimmunity. 2009, Nov-Dec; 33(3-4): 275-281.
  1. 6.   Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition
  2. Hallett, W.; Ames, E.; Motarjemi, M.; Barao, I.; Shanker, A.; Tamang, D. L.; Sayers, T. J.; Hudig, D.; Murphy, W. J.
  3. Journal of Immunology. 2008 180(1): 163-170.
  1. 7.   Productively combining proteasome inhibition with the immunotherapy of cancer
  2. Sayers, T.
  3. Journal of Molecular Medicine-jmm. 2008 86(8): 857-860.
  1. 8.   T cell tolerance to tumors and cancer immunotherapy
  2. Shafer-Weaver, K.; Anderson, M.; Malyguine, A.; Hurwitz, A. A.
  3. Immune-Mediated Diseases: From Theory to Therapy. 2007; 601 : 357-368.
  1. 9.   NK cells use NKG2D to recognize a mouse renal cancer (Renca), yet require intercellular adhesion molecule-1 expression on the tumor cells for optimal perforin-dependent effector function
  2. Abdool, K.; Cretney, E.; Brooks, A. D.; Kelly, J. M.; Swann, J.; Shanker, A.; Bere, E. W.; Yokoyama, W. M.; Ortaldo, J. R.; Smyth, M. J.; Sayers, T. J.
  3. Journal of Immunology. 2006, Aug; 177(4): 2575-2583.
  1. 10.   TNF-related apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer
  2. Cretney, E.; Shanker, A.; Yagita, H.; Smyth, M. J.; Sayers, T. J.
  3. Immunology and Cell Biology. 2006, FEB; 84(1): 87-98.
  1. 11.   Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy
  2. Sayers, T. J.; Murphy, W. J.
  3. Cancer Immunology Immunotherapy. 2006, JAN; 55(1): 76-84.
  1. 13.   TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells
  2. Herbeuval, J. P.; Boasso, A.; Grivel, J. C.; Hardy, A. W.; Anderson, S. A.; Dolan, M. J.; Chougnet, C.; Lifson, J. D.; Shearer, G. M.
  3. Blood. 2005 105(6): 2458-2464.
  1. 14.   NKG2D recognition and perforin effector function mediate effective cytokine immunotherapy of cancer
  2. Smyth, M. J.; Swann, J.; Kelly, J. M.; Cretney, E.; Yokoyama, W. M.; Diefenbach, A.; Sayers, T. J.; Hayakawa, Y.
  3. Journal of Experimental Medicine. 2004, NOV 15; 200(10): 1325-1335.
  1. 15.   Nitric oxide, a mediator of inflammation, suppresses tumorigenesis
  2. Hussain, S. P.; Trivers, G. E.; Hofseth, L. J.; He, P. J.; Shaikh, I.; Mechanic, L. E.; Doja, S.; Jiang, W. D.; Subleski, J.; Shorts, L.; Haines, D.; Laubach, V. E.; Wiltrout, R. H.; Djurickovic, D.; Harris, C. C.
  3. Cancer Research. 2004, OCT 1; 64(19): 6849-6853.
  1. 16.   Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) and TRAIL receptor expression in human neutrophils
  2. Kamohara, H.; Matsuyama, W.; Shimozato, O.; Abe, K.; Galligan, C.; Hashimoto, S. I.; Matsushima, K.; Yoshimura, T.
  3. Immunology. 2004 111(2): 186-194.
  1. 17.   Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy
  2. Takeda, K.; Yamaguchi, N.; Akiba, H.; Kojima, Y.; Hayakawa, Y.; Tanner, J. E.; Sayers, T. J.; Seki, N.; Okumura, K.; Yagita, H.; Smyth, M. J.
  3. Journal of Experimental Medicine. 2004 199(4): 437-448.
  1. 18.   Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques - Evidence that dendritic cells are early and sustained targets of infection
  2. Geisbert, T. W.; Hensley, L. E.; Larsen, T.; Young, H. A.; Reed, D. S.; Geisbert, J. B.; Scott, D. P.; Kagan, E.; Jahrling, P. B.; Davis, K. J.
  3. American Journal of Pathology. 2003 163(6): 2347-2370.
  1. 19.   NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade
  2. Koh, C. Y.; Ortaldo, J. R.; Blazar, B. R.; Bennett, M.; Murphy, W. J.
  3. Blood. 2003 102(12): 4067-4075.
  1. 20.   Antigen-primed CD8(+) T cells can mediate resistance, preventing allogeneic marrow engraftment in the simultaneous absence of perforin-, CD95L-, TNFR1- and TRAIL-dependent killing
  2. Komatsu, M.; Mammolenti, M.; Jones, M.; Jurecic, R.; Sayers, T. J.; Levy, R. B.
  3. Blood. 2003 101(10): 3991-3999.
  1. 21.   Regulation of natural killer cell function
  2. Makrigiannis, A. P.; Anderson, S. K.
  3. Cancer Biology & Therapy. 2003, NOV-DEC; 2(6): 610-616.
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