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  1. 1.   Chronic Low-Level IFN-gamma Expression Disrupts Mitochondrial Complex I Activity in Renal Macrophages: An Early Mechanistic Driver of Lupus Nephritis Pathogenesis
  2. Bae, Heekyong R; Shin, Su-Kyung; Lee, Ji-Yoon; Ko, Yeo Jin; Kim, Suntae; Young,Howard; Kwon, Eun-Young
  3. International Journal of Molecular Sciences. 2024, Dec 25; 26(1):
  1. 2.   The common variable immunodeficiency IgM repertoire narrowly recognizes erythrocyte and platelet glycans
  2. Le Coz, Carole; Trofa, Melissa; Butler, Dorothy L; Yoon, Samuel; Tian, Tian; Reid, Whitney; Cruz Cabrera, Emylette; Knox, Ainsley V C; Khanna, Caroline; Sullivan, Kathleen E; Heimall, Jennifer; Takach, Patricia; Fadugba, Olajumoke O; Lawrence, Monica; Jyonouchi, Soma; Hakonarson, Hakon; Wells, Andrew D; Handler, Steven; Zur, Karen B; Pillai, Vinodh; Gildersleeve,Jeffrey; Romberg, Neil
  3. The Journal of Allergy and Clinical Immunology. 2024, Apr 29;
  1. 3.   HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells
  2. Zecher, Britta F; Ellinghaus, David; Schloer, Sebastian; Niehrs, Annika; Padoan, Benedetta; Baumdick, Martin E; Yuki,Yuko; Martin, Maureen P; Glow, Dawid; Schröder-Schwarz, Jennifer; Niersch, Jennifer; Brias, Sébastien; Müller, Luisa M; Habermann, Robin; Kretschmer, Paul; Früh, Tristan; Dänekas, Janis; Wehmeyer, Malte H; Poch, Tobias; Sebode, Marcial; Ellinghaus, Eva; Degenhardt, Frauke; Körner, Christian; Hoelzemer, Angelique; Fehse, Boris; Oldhafer, Karl J; Schumacher, Udo; Sauter, Guido; Carrington,Mary; Franke, Andre; Bunders, Madeleine J; Christoph, Schramm; Altfeld, Marcus
  3. Gut. 2023, Oct 03;
  1. 4.   Chronic inflammation in high-fat diet-fed mice: Unveiling the early pathogenic connection between liver and adipose tissue
  2. Bae, Heekyong R; Shin, Su-Kyung; Yoo, Ji-Hyeon; Kim, Suntae; Young,Howard; Kwon, Eun-Young
  3. Journal of Autoimmunity. 2023, Aug 16; 139: 103091.
  1. 5.   IFN-gamma and androgens disrupt mitochondrial function in murine myocytes
  2. Fenimore, John M; Springer, Danielle A; Romero, Maria E; Edmondson,Elijah; McVicar,Daniel; Yanpallewar, Sudhirkumar; Sanford,Michael; Spindel, Thea; Engle, Elizabeth; Meyer, Thomas J; Valencia,Julio; Young,Howard
  3. The Journal of Pathology. 2023, Apr 27;
  1. 6.   IFN gamma Is a Key Link between Obesity and Th1-Mediated AutoImmune Diseases
  2. Bae,Heekyong; Choi, Myung-Sook; Kim, Suntae; Young,Howard; Gershwin, M. Eric; Jeon, Seon-Min; Kwon, Eun-Young
  3. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021, Jan; 22(1):
  1. 7.   Natural Killer Cell Transcript 4 promotes the development of Sjogren's syndrome via activation of Rap1 on B cells
  2. Qu, Peng; Wuest, Todd; Min,Yongfen; Alevizos, Ilias; Young,Howard; Lin,Charles
  3. JOURNAL OF AUTOIMMUNITY. 2021, Jan; 116
  1. 8.   Type I IFN signaling in T regulatory cells modulates chemokine production and myeloid derived suppressor cells trafficking during EAE
  2. Tanwar, Shalini; Oguz,Cihan; Metidji, Amina; Dahlstrom, Eric; Barbian, Kent; Kanakabandi, Kishore; Sykora, Lydia; Shevach, Ethan M
  3. Journal of autoimmunity. 2020, DEC; 115: 102525.
  1. 9.   Multi-omics: Differential expression of IFN-? results in distinctive mechanistic features linking chronic inflammation, gut dysbiosis, and autoimmune diseases
  2. Bae,Heekyong; Leung, Patrick S C; Hodge, Deborah L; Fenimore,John; Jeon, Seon-Min; Thovarai,Vishal; Dzutsev,Amiran; Welcher, Andrew A; Boedigheimer, Michael; Damore, Michael A; Choi, Myung-Sook; Fravell, Richard A; Trinchieri,Giorgio; Gershwin, M Eric; Young,Howard
  3. Journal of autoimmunity. 2020, JUL; 111: 102436.
  1. 10.   Tissue specific production of MicroRNA-155 inhibits melanocortin 5 receptor dependent suppressor macrophages to promote experimental autoimmune uveitis
  2. Muhammad, Fauziyya; Trivett,Anna; Wang, Dawei; Lee, Darren J
  3. European journal of immunology. 2019, Nov; 49(11): 2074-2082.
  1. 11.   Corrigendum: Paradoxical CD4 Lymphopenia in Autoimmune Lymphoproliferative Syndrome (ALPS)
  2. Lisco, Andrea; Wong, Chun-Shu; Price, Susan; Ye, Peiying; Niemela, Julie; Anderson, Megan; Richards, Elizabeth; Manion, Maura; Mystakelis, Harry; Similuk, Morgan; Lo, Bernice; Stoddard, Jennifer; Rosenzweig, Sergio; Vanpouille, Christophe; Rupert,Adam; Maric, Irina; Perez-Diez, Ainhoa; Parenti, David; Burbelo, Peter D.; Rao, V. Koneti; Sereti, Irini
  3. Frontiers in immunology. 2019, Jul 4; 10
  1. 12.   Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis
  2. Hu, Yingwen; Wang, Bingbing; Shen, Jiayin; Low, Stewart A; Putt, Karson S; Niessen, Hans W M; Matteson, Eric L; Murphy, Linda; Ruppert, Clemens; Jansen, Gerrit; Oliver, Stephen J; Feng,Yang; Dimitrov, Dimiter S; Nickerson-Nutter, Cheryl; Low, Philip S
  3. Arthritis research & therapy. 2019, Jun 07; 21(1): 143.
  1. 13.   Identification of rare HIV-1-infected patients with extreme CD4(+) T cell decline despite ART-mediated viral suppression
  2. Lisco, Andrea; Wong, Chun-Shu; Lage, Silvia Lucena; Levy, Itzchak; Brophy, Jason; Lennox, Jeffrey; Manion, Maura; Anderson, Megan; Mejia, Yolanda; Grivas, Christopher; Mystakelis, Harry; Burbelo, Peter D.; Perez-Diez, Ainhoa; Rupert,Adam; Martens, Craig A.; Anzick, Sarah L.; Morse, Caryn; Chan, Shanna; Deleage,Claire; Sereti, Irini
  3. JCI INSIGHT. 2019, APR 18; 4(8): pii: 127113.
  1. 14.   Autoimmunity and Cancer, the Paradox Comorbidities Challenging Therapy in the Context of Preexisting Autoimmunity
  2. Valencia,Julio; Egbukichi, Nkolika; Erwin-Cohen,Rebecca
  3. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. 2019, JAN 1; 39(1): 72-84.
  1. 15.   Current prospects of type II interferon signaling and autoimmunity
  2. Green, Daniel S.; Young, Howard; Valencia, Julio
  3. Journal of Biological Chemistry. 2017, Aug 25; 292(34): 13925-13933.
  1. 16.   Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis
  2. Zhu, Feng; Willette Brown, Jami; Song, Na-Young; Lomada, Dakshayani; Song, Yongmei; Xue, Liyan; Gray, Zane; Zhao, Zitong; Davis, Sean R; Sun, David; Zhang, Peilin; Wu, Xiaolin; Zhan, Qimin; Richie, Ellen R; Hu, Yinling
  3. Cell Host & Microbe. 2017, Apr 12; 21(4): 478-493.e7.
  1. 17.   Polymorphisms in complement system genes and risk of non-Hodgkin lymphoma
  2. Bassig, B. A.; Zheng, T. Z.; Zhang, Y. W.; Berndt, S. I.; Holford, T. R.; Hosgood, H. D.; Hu, W.; Leaderer, B.; Yeager, M.; Menashe, I.; Boyle, P.; Xu, J.; Zou, K. Y.; Zhu, Y.; Chanock, S.; Rothman, N.; Lan, Q.
  3. Environmental and Molecular Mutagenesis. 2012, Mar; 53(2): 145-151.
  1. 18.   The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4(+) FoxP3(+) regulatory T cells
  2. Chen, X.; Oppenheim, J. J.
  3. Immunology. 2011, Aug; 133(4): 426-433.
  1. 19.   CpG DNA as a vaccine adjuvant
  2. Bode, C.; Zhao, G.; Steinhagen, F.; Kinjo, T.; Klinman, D. M.
  3. Expert Review of Vaccines. 2011, Apr; 10(4): 499-511.
  1. 20.   Possession of HLA Class II DRB1*1303 Associates with Reduced Viral Loads in Chronic HIV-1 Clade C and B Infection
  2. Julg, B.; Moodley, E. S.; Qi, Y.; Ramduth, D.; Reddy, S.; Mncube, Z.; Gao, X. J.; Goulder, P. J.; Detels, R.; Ndung'u, T.; Walker, B. D.; Carrington, M.
  3. Journal of Infectious Diseases. 2011, Mar; 203(6): 803-809.
  1. 21.   Gene Expression Profiles in a Rabbit Model of Systemic Lupus Erythematosus Autoantibody Production
  2. Rai, G.; Ray, S.; Milton, J.; Yang, J.; Ren, P.; Lempicki, R.; Mage, R. G.
  3. Journal of Immunology. 2010, Oct; 185(7): 4446-4456.
  1. 22.   Synergy of IL-23 and Th17 Cytokines: New Light on Inflammatory Bowel Disease
  2. Shen, W.; Durum, S. K.
  3. Neurochemical Research. 2010, Jun; 35(6): 940-946.
  1. 23.   Specific Human Leukocyte Antigen Class I and II Alleles Associated with Hepatitis C Virus Viremia
  2. Kuniholm, M. H.; Kovacs, A.; Gao, X. J.; Xue, X. N.; Marti, D.; Thio, C. L.; Peters, M. G.; Terrault, N. A.; Greenblatt, R. M.; Goedert, J. J.; Cohen, M. H.; Minkoff, H.; Gange, S. J.; Anastos, K.; Fazzari, M.; Harris, T. G.; Young, M. A.; Strickler, H. D.; Carrington, M.
  3. Hepatology. 2010, May; 51(5): 1514-1522.
  1. 24.   FDA guidance on prophylactic DNA vaccines: Analysis and recommendations
  2. Klinman, D. M.; Klaschik, S.; Tross, D.; Shirota, H.; Steinhagen, F.
  3. Vaccine. 2010, Apr; 28(16): 2801-2805.
  1. 25.   TNF-alpha: an activator of CD4+FoxP3+TNFR2+ regulatory T cells
  2. Chen, X.; Oppenheim, J. J.
  3. Current directions in autoimmunity. 2010 11: 119-34.
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