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  1. 1.   Fifty Years of Diazeniumdiolate Research. From Laboratory Curiosity to Broad-Spectrum Biomedical Advances
  2. Keefer, L. K.
  3. Acs Chemical Biology. 2011, Nov; 6(11): 1147-1155.
  1. 2.   Comparison of the NO and HNO donating properties of diazeniumdiolates: Primary amine adducts release HNO in vivo
  2. Miranda, K. M.; Katori, T.; de Holding, C. L. T.; Thomas, L.; Ridnour, L. A.; MeLendon, W. J.; Cologna, S. M.; Dutton, A. S.; Champion, H. C.; Mancardi, D.; Tocchetti, C. G.; Saavedra, J. E.; Keefer, L. K.; Houk, K. N.; Fukuto, J. M.; Kass, D. A.; Paolocci, N.; Wink, D. A.
  3. Journal of Medicinal Chemistry. 2005, DEC 29; 48(26): 8220-8228.
  1. 3.   Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells
  2. Ben-Kasus, T.; Ben-Zvi, Z.; Marquez, V. E.; Kelley, J. A.; Agbaria, R.
  3. Biochemical Pharmacology. 2005, JUL 1; 70(1): 121-133.
  1. 4.   Effect of structure and sequence on mutations induced by site-specific polycyclic aromatic hydrocarbon diol epoxide-DNA adducts
  2. Ponten, I.
  3. Mutagenesis. 2004, NOV; 19(6): 499, Abstract 3-500, Abstract 3.
  1. 5.   Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion
  2. Saavedra, J. E.; Bohle, D. S.; Smith, K. N.; George, C.; Deschamps, J. R.; Parrish, D.; Ivanic, J.; Wang, Y. N.; Citro, M. L.; Keefer, L. K.
  3. Journal of the American Chemical Society. 2004, OCT 13; 126(40): 12880-12887.
  1. 6.   The experimental antitumor agents Phortress and Doxorubicin are equiactive against human-derived breast carcinoma xenograft models
  2. Fichtner, I.; Monks, A.; Hose, C.; Stevens, M. F. G.; Bradshaw, T. D.
  3. Breast Cancer Research and Treatment. 2004, SEP; 87(1): 97-107.
  1. 7.   Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway
  2. Chen, S. Y.; Lin, J. R. V.; Darbha, R.; Lin, P. P.; Liu, T. Y.; Chen, Y. M. A.
  3. Cancer Research. 2004 64(10): 3617-3623.
  1. 8.   The repair of the tobacco specific nitrosamine derived adduct O-6-[4-oxo-4-(3-pyridyl)butyl]guanine by O-6-alkylguanine-DNA alkyltransferase variants
  2. Mijal, R. S.; Thomson, N. M.; Fleischer, N. L.; Pauly, G. T.; Moschel, R. C.; Kanugula, S.; Fang, Q. M.; Pegg, A. E.; Peterson, L. A.
  3. Chemical Research in Toxicology. 2004 17(3): 424-434.
  1. 9.   DNA damage and cell cycle arrest induced by 2-(4-amino-3- methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells
  2. Trapani, V.; Patel, V.; Leong, C. O.; Ciolino, H. P.; Yeh, G. C.; Hose, C.; Trepel, J. B.; Stevens, M. F. G.; Sausville, E. A.; Loaiza-Perez, A. I.
  3. British Journal of Cancer. 2003 88(4): 599-605.
  1. 10.   The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen-induced hepatotoxicity in mice
  2. Liu, J.; Li, C. X.; Waalkes, M. P.; Clark, J.; Myers, P.; Saavedra, J. E.; Keefer, L. K.
  3. Hepatology. 2003 37(2): 324-333.
  1. 11.   Site-specific mutagenesis in Escherichia coli by N-2- deoxyguanosine adducts derived from the highly carcinogenic fjord-region benzo c phenanthrene 3,4-diol 1,2-epoxides
  2. Ramos, L. A.; Ponten, I.; Dipple, A.; Kumar, S.; Yagi, H.; Sayer, J. M.; Kroth, H.; Kalena, G.; Jerina, D. M.
  3. Chemical Research in Toxicology. 2002 15(12): 1619-1626.
  1. 12.   Mutational consequences on replication of M13 constructs containing isomeric diol epoxide adducts in E. Coli
  2. Sayer, J. M.; Kroth, H.; Yagi, H.; Kalena, G.; Jerina, D. M.; Ramos, L. A.; Dipple, A.; Ponten, I.; Goodman, M. E.
  3. Polycyclic Aromatic Compounds. 2002 22(3-4): 871-879.
  1. 13.   Human topoisomerase I inhibition: Docking camptothecin and derivatives into a structure-based active site model
  2. Laco, G. S.; Collins, J. R.; Luke, B. T.; Kroth, H.; Sayer, J. M.; Jerina, D. M.; Pommier, Y.
  3. Biochemistry. 2002 41(5): 1428-1435.
  1. 14.   Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines
  2. Khan, Q. A.; Anderson, L. M.
  3. Toxicology and Applied Pharmacology. 2001 173(2): 105-113.
  1. 15.   Effect of benzo-ring hydroxyl groups on site-specific mutagenesis by tetrahydrobenzo a pyrene adducts at N-6 of deoxyadenosine
  2. Ramos, L. A.; Sayer, J. M.; Yagi, H.; Shah, J. H.; Dipple, A.; Jerina, D. M.
  3. Chemical Research in Toxicology. 2001 14(8): 1082-1089.
  1. 16.   Modulation of glucose-6-phosphate dehydrogenase activity and expression is associated with aryl hydrocarbon resistance in vitro
  2. Yeh, G. C.; Daschner, P. J.; Lopaczynska, J.; MacDonald, C. J.; Ciolino, H. P.
  3. Journal of Biological Chemistry. 2001 276(37): 34708-34713.
  1. 17.   Mutagenicity of benzo [a]pyrene-deoxyadenosine adducts in a sequence context derived from the p53 gene
  2. Khalili, H.; Zhang, F. J.; Harvey, R. G.; Dipple, A.
  3. Mutation Research-Genetic Toxicology & Environmental Mutagenesis. 2000 465(1-2): 39-44.
  1. 18.   Quantitative reactions of anti 5,9-dimethylchrysene dihydrodiol epoxide with DNA and deoxyribonucleotides
  2. Szeliga, J.; Amin, S.
  3. Chemico-Biological Interactions. 2000 128(3): 159-172.
  1. 19.   Factors determining mutagenic potential for individual cis and trans opened benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts
  2. Ponten, I.; Sayer, J. M.; Pilcher, A. S.; Yagi, H.; Kumar, S.; Jerina, D. M.; Dipple, A.
  3. Biochemistry. 2000 39(14): 4136-4144.
  1. 20.   Mutational spectra for polycyclic aromatic hydrocarbons in the supF target gene
  2. Bigger, C. A. H.; Ponten, I.; Page, J. E.; Dipple, A.
  3. Mutation Research - Fundamental & Molecular Mechanisms of Mutagenesis. 2000 450(1-2 Special Issue SI): 75-93.
  1. 21.   DNA adducts from syn 7-methylbenz
  2. Szeliga, J.; Harvey, R. G.; Cortez, C.; Dipple, A.
  3. Polycyclic Aromatic Compounds. 1999 13(1): 41-53.
  1. 22.   Mutational consequences of replication of M13mp7L2 constructs containing cis-opened benzo
  2. Page, J. E.; Pilcher, A. S.; Yagi, H.; Sayer, J. M.; Jerina, D. M.; Dipple, A.
  3. Chemical Research in Toxicology. 1999 12(3): 258-263.
  1. 23.   Site-specific mutagenesis with benzo
  2. Page, J. E.; Liang, C. Y.; Sayer, J. M.; Jerina, D. M.; Dipple, A.
  3. Polycyclic Aromatic Compounds. 1999 16(1-4): 99-108.
  1. 24.   Sequence context effects on mutational properties of cis-opened benzo
  2. Ponten, I.; Sayer, J. M.; Pilcher, A. S.; Yagi, H.; Kumar, S.; Jerina, D. M.; Dipple, A.
  3. Biochemistry. 1999 38(3): 1144-1152.
  1. 25.   Metabolic activation of 4H-cyclopenta
  2. Agarwal, R.; Coffing, S. L.; Baird, W. M.; Harvey, R. G.; Dipple, A.
  3. Chemical Research in Toxicology. 1999 12(5): 437-441.
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