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  1. 1.   RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo
  2. Sebastiani, Jessica; Puxeddu, Michela; Nalli, Marianna; Bai,Ruoli; Altieri, Ludovica; Rovella, Paola; Gaudio, Eugenio; Trisciuoglio, Daniela; Spriano, Filippo; Lavia, Patrizia; Fionda, Cinzia; Masci, Domiziana; Urbani, Andrea; Bigogno, Chiara; Dondio, Giulio; Hamel,Ernest; Bertoni, Francesco; Silvestri, Romano; La Regina, Giuseppe
  3. European Journal of Medicinal Chemistry. 2022, Dec 05; 246: 114997.
  1. 2.   Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors
  2. Spano, Virginia; Barreca, Marilia; Rocca, Roberta; Bortolozzi, Roberta; Bai, Ruoli; Carbone, Anna; Raimondi, Maria Valeria; Piccionello, Antonio Palumbo; Montalbano, Alessandra; Alcaro, Stefano; Hamel, Ernest; Viola, Giampietro; Barraja, Paola
  3. European Journal of Medicinal Chemistry. 2021, Feb 15; 212
  1. 3.   Significance of pro-angiogenic estrogen metabolites in normal follicular development and follicular growth arrest in polycystic ovary syndrome
  2. Henríquez, Soledad; Kohen, Paulina; Xu,Xia; Villarroel, Claudio; Muñoz, Alex; Godoy, Ana; Strauss, Jerome F; Devoto, Luigi
  3. Human reproduction (Oxford, England). 2020, JUL; 35(7): 1655-1665.
  1. 4.   Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
  2. Magnussen, Helge M.; Ahmed, Syed F.; Sibbet, Gary J.; Hristova, Ventzislava A.; Nomura, Koji; Hock, Andreas K.; Archibald, Lewis J.; Jamieson, Andrew G.; Fushman, David; Vousden, Karen H.; Weissman, Allan M.; Huang, Danny T.
  3. Nature communications. 2020, Apr 29; 11(1):
  1. 5.   Regulation of senescence and the SASP by the transcription factor C/EBP beta
  2. Salotti,Jacqueline; Johnson,Peter
  3. Experimental gerontology. 2019, Dec; 128
  1. 6.   C/EBPd protects from radiation-induced intestinal injury and sepsis by suppression of inflammatory and nitrosative stress
  2. Banerjee, Sudip; Fu, Qiang; Shah, Sumit K; Melnyk, Stepan B; Sterneck,Esta; Hauer-Jensen, Martin; Pawar, Snehalata A
  3. Scientific reports. 2019, Sep 27; 9(1): 13953.
  1. 7.   Cryptotanshinone has curative dual anti-proliferative and immunotherapeutic effects on mouse Lewis lung carcinoma
  2. Liu, Shuo; Han, Zhen; Trivett,Anna; Lin, Hongsheng; Hannifin,Sean; Yang,De; Oppenheim,Joost
  3. Cancer immunology, immunotherapy : CII. 2019, JUL; 68(7): 1059-1071.
  1. 8.   Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-Kras(G12D/+);Tp53(R172H/+) (KPC) mice, a genetically engineered model of pancreatic cancer
  2. Vilimas, Tomas; Wang, Amy Q.; Patnaik, Samarjit; Hughes, Emma A.; Singleton, Marc D.; Knotts, Zachary; Li, Dandan; Frankowski, Kevin; Schlomer, Jerome; Guerin, Theresa; Springer, Stephanie; Drennan, Catherine; Dextras, Christopher; Wang, Chen; Gilbert, Debra; Southall, Noel; Ferrer, Marc; Huang, Sui; Kozlov, Serguei; Marugan, Juan; Xu, Xin; Rudloff, Udo
  3. CANCER CHEMOTHERAPY AND PHARMACOLOGY. 2018, Dec; 82(6): 1067-1080.
  1. 9.   Biased antagonism of CXCR4 avoids antagonist tolerance
  2. Hitchinson, Ben; Eby, Jonathan M.; Gao, Xianlong; Guite-Vinet, Francois; Ziarek, Joshua J.; Abdelkarim, Hazem; Lee, Youngshim; Okamoto, Yukari; Shikano, Sojin; Majetschak, Matthias; Heveker, Nikolaus; Volkman, Brian F.; Tarasova,Nadya; Gaponenko, Vadim
  3. Science signaling. 2018, Oct 16; 11(552):
  1. 10.   DNA Methyltransferase Inhibitor, Zebularine, Delays Tumor Growth and Induces Apoptosis in a Genetically Engineered Mouse Model of Breast Cancer
  2. Chen, M.; Shabashvili, D.; Nawab, A.; Yang, S. X.; Dyer, L. M.; Brown, K. D.; Hollingshead, M.; Hunter, K. W.; Kaye, F. J.; Hochwald, S. N.; Marquez, V. E.; Steeg, P.; Zajac-Kaye, M.
  3. Molecular Cancer Therapeutics. 2012, Feb; 11(2): 370-382.
  1. 11.   Identification of a Src Tyrosine Kinase/SIAH2 E3 Ubiquitin Ligase Pathway That Regulates C/EBP delta Expression and Contributes to Transformation of Breast Tumor Cells
  2. Sarkar, T. R.; Sharan, S.; Wang, J.; Pawar, S. A.; Cantwell, C. A.; Johnson, P. F.; Morrison, D. K.; Wang, J. M.; Sterneck, E.
  3. Molecular and Cellular Biology. 2012, Jan; 32(2): 320-332.
  1. 12.   3 ' UTR elements inhibit Ras-induced C/EBP beta post-translational activation and senescence in tumour cells
  2. Basu, S. K.; Malik, R.; Huggins, C. J.; Lee, S.; Sebastian, T.; Sakchaisri, K.; Quinones, O. A.; Alvord, W. G.; Johnson, P. F.
  3. Embo Journal. 2011, Sep; 30(18): 3714-3728.
  1. 13.   Dysregulated Delta Np63 alpha Inhibits Expression of Ink4a/arf, Blocks Senescence, and Promotes Malignant Conversion of Keratinocytes
  2. Ha, L. A.; Ponnamperuma, R. M.; Jay, S.; Ricci, M. S.; Weinberg, W. C.
  3. Plos One. 2011, Jul; 6(7): 13.
  1. 14.   Toll-Like Receptor 9 Is Required for Opioid-Induced Microglia Apoptosis
  2. He, L.; Li, H.; Chen, L.; Miao, J. Y.; Jiang, Y. L.; Zhang, Y.; Xiao, Z. X.; Hanley, G.; Li, Y.; Zhang, X. M.; LeSage, G.; Peng, Y.; Yin, D. L.
  3. Plos One. 2011, Apr; 6(4): 10.
  1. 15.   The tumour suppressor C/EBP delta inhibits FBXW7 expression and promotes mammary tumour metastasis
  2. Balamurugan, K.; Wang, J. M.; Tsai, H. H.; Sharan, S.; Anver, M.; Leighty, R.; Sterneck, E.
  3. Embo Journal. 2010, Dec; 29(24): 4106-4117.
  1. 16.   C/EBP ? targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression
  2. Pawar, S. A.; Sarkar, T. R.; Balamurugan, K.; Sharan, S.; Wang, J.; Zhang, Y. H.; Dowdy, S. F.; Huang, A. M.; Sterneck, E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2010, May 18; 107(20): 9210-9215.
  1. 17.   In vitro and In vivo Radiosensitization with AZD6244 (ARRY-142886), an Inhibitor of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase 1/2 Kinase
  2. Chung, E. J.; Brown, A. P.; Asano, H.; Mandler, M.; Burgan, W. E.; Carter, D.; Camphausen, K.; Citrin, D.
  3. Clinical Cancer Research. 2009 15(9): 3050-3057.
  1. 18.   Growth inhibition of hepatocellular carcinoma cells in vitro and in vivo by the 8-methoxy analog of WMC79
  2. Kosakowska-Cholody, T.; Cholody, W. M.; Hariprakasha, H. K.; Monks, A.; Kar, S.; Wang, M. F.; Michejda, C. J.; Carr, B. I.
  3. Cancer Chemotherapy and Pharmacology. 2009 63(5): 769-778.
  1. 19.   Ras(V12)-Mediated Down-regulation of CCAAT/Enhancer Binding Protein beta in Immortalized Fibroblasts Requires Loss of p19(Arf) and Facilitates Bypass of Oncogene-Induced Senescence
  2. Sebastian, T.; Johnson, P. F.
  3. Cancer Research. 2009 69(6): 2588-2598.
  1. 20.   Recruitment of a SAP18-HDAC1 Complex into HIV-1 Virions and Its Requirement for Viral Replication
  2. Sorin, M.; Cano, J.; Das, S.; Mathew, S.; Wu, X. H.; Davies, K. P.; Shi, X. L.; Cheng, S.; Ott, D.; Kalpana, G. V.
  3. Plos Pathogens. 2009 5(6):
  1. 21.   Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients
  2. Abbatiello, S. E.; Pan, Y. X.; Zhou, M.; Wayne, A. S.; Veenstra, T. D.; Hunger, S. P.; Kilberg, M. S.; Eyler, J. R.; Richards, N.; Conrads, T. P.
  3. Journal of Proteomics. 2008 71(1): 61-70.
  1. 22.   Cell-nonautonomous function of ceramidase in photoreceptor homeostasis
  2. Acharya, J. K.; Dasgupta, U.; Rawat, S. S.; Yuan, C. Q.; Sanxaridis, P. D.; Yonamine, I.; Karim, P.; Nagashima, K.; Brodsky, M. H.; Tsunoda, S.; Acharya, U.
  3. Neuron. 2008 57(1): 69-79.
  1. 23.   Genomic profiling of MicroRNA and messenger RNA reveals deregulated MicroRNA expression in prostate cancer
  2. Ambs, S.; Prueitt, R. L.; Yi, M.; Hudson, R. S.; Howe, T. M.; Petrocca, F.; Wallace, T. A.; Liu, C. G.; Volinia, S.; Calin, G. A.; Yfantis, H. G.; Stephens, R. M.; Croce, C. M.
  3. Cancer Research. 2008 68(15): 6162-6170.
  1. 24.   Rtf1-mediated eukaryotic site-specific replication termination
  2. Eydmann, T.; Sommariva, E.; Inagawa, T.; Mian, S.; Klar, A.; Dalgaard, J. Z.
  3. Genetics. 2008 180(1): 27-39.
  1. 25.   Covalent binding to tubulin by isothiocyanates - A mechanism of cell growth arrest and apoptosis
  2. Mi, L. X.; Xiao, Z.; Hood, B. L.; Dakshanamurthy, S.; Wang, X. T.; Govind, S.; Conrads, T. P.; Veenstra, T. D.; Chung, F. L.
  3. Journal of Biological Chemistry. 2008 283(32): 22136-22146.
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