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  1. 1.   The mechanism of Raf activation through dimerization
  2. Zhang,Mingzhen; Maloney,Ryan; Jang,Hyunbum; Nussinov,Ruth
  3. Chemical Science. 2021, Dec 08; 12(47): 15609-15619.
  1. 2.   The mechanism of activation of monomeric B-Raf V600E
  2. Maloney,Ryan; Zhang,Mingzhen; Jang,Hyunbum; Nussinov,Ruth
  3. Computational and structural biotechnology journal. 2021, Jun 4; 19: 3349-3363.
  1. 3.   The Mystery of Rap1 Suppression of Oncogenic Ras
  2. Nussinov,Ruth; Jang,Hyunbum; Zhang,Mingzhen; Tsai,Chung-Jung; Sablina, Anna A.
  3. Trends in cancer. 2020, May; 6(5): 369-379.
  1. 4.   Does Ras Activate Raf and PI3K Allosterically?
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. Frontiers in oncology. 2019, Nov 15; 9
  1. 5.   Synthesis and Biological Evaluation of New Madecassic Acid Derivatives Targeting ERK Cascade Signaling
  2. Valdeira, Ana S C; Ritt,Daniel; Morrison,Deborah; McMahon, James B; Gustafson, Kirk R; Salvador, Jorge A R
  3. Frontiers in chemistry. 2018, Sep 28; 6: 434.
  1. 6.   KIT Suppresses BRAF(V600E)-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling
  2. Neiswender, James V.; Kortum, Robert L.; Bourque, Caitlin; Kasheta, Melissa; Zon, Leonard I.; Morrison, Deborah; Ceol, Craig J.
  3. Cancer Research. 2017, Nov 01; 77(21): 5820-5830.
  1. 7.   RAF Inhibitor-Induced KSR1/B-RAF Binding and Its Effects on ERK Cascade Signaling
  2. McKay, M. M. M. M. M.; Ritt, D. A.; Morrison, D. K.
  3. Current Biology. 2011, Apr; 21(7): 563-568.
  1. 8.   AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
  2. Smith, F. D.; Langeberg, L. K.; Cellurale, C.; Pawson, T.; Morrison, D. K.; Davis, R. J.; Scott, J. D.
  3. Nature Cell Biology. 2010, Dec; 12(12): 1242-U287.
  1. 9.   RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis
  2. Satyanarayana, A.; Gudmundsson, K. O.; Chen, X.; Coppola, V.; Tessarollo, L.; Keller, J. R.; Hou, S. X.
  3. Blood. 2010, Oct; 116(16): 2921-2931.
  1. 10.   Signaling dynamics of the KSR1 scaffold complex
  2. McKay, M. M.; Ritt, D. A.; Morrison, D. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009, Jul 7; 106(27): 11022-7.
  1. 12.   Regulation of raf-1 by direct feedback phosphorylation
  2. Dougherty, M. K.; Muller, J.; Ritt, D. A.; Zhou, M.; Zhou, X. Z.; Copeland, T. D.; Conrads, T. P.; Veenstra, T. D.; Lu, K. P.; Morrison, D. K.
  3. Molecular Cell. 2005, JAN 21; 17(2): 215-224.
  1. 13.   Involvement of domain II in toxicity of anthrax lethal factor
  2. Liang, X. D.; Young, J. J.; Boone, S. A.; Waugh, D. S.; Duesbery, N. S.
  3. Journal of Biological Chemistry. 2004, DEC 10; 279(50): 52473-52478.
  1. 14.   Craf-1 Protein Kinase Is Essential For Mouse Development
  2. Wojnowski, L.; Stancato, L. F.; Zimmer, A. M.; Hahn, H.; Beck, T. W.; Larner, A. C.; Rapp, U. R.; Zimmer, A.
  3. Mechanisms of Development. 1998 76(1-2): 141-149.
  1. 15.   Endothelial Apoptosis in Braf-Deficient Mice
  2. Wojnowski, L.; Zimmer, A. M.; Beck, T. W.; Hahn, H.; Bernal, R.; Rapp, U. R.; Zimmer, A.
  3. Nature Genetics. 1997 16(3): 293-297.
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