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  1. 1.   Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization
  2. Hauseman, Zachary J; Harvey, Edward P; Newman, Catherine E; Wales, Thomas E; Bucci, Joel C; Mintseris, Julian; Schweppe, Devin K; David, Liron; Fan,Lixin; Cohen, Daniel T; Herce, Henry D; Mourtada, Rida; Ben-Nun, Yael; Bloch, Noah B; Hansen, Scott B; Wu, Hao; Gygi, Steven P; Engen, John R; Walensky, Loren D
  3. Molecular cell. 2020, JUL 2; 79(1): 68-+.
  1. 2.   The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells
  2. Giuliani, Angelica; Cirilli, Ilenia; Prattichizzo, Francesco; Mensa, Emanuela; Fulgenzi, Gianluca; Sabbatinelli, Jacopo; Graciotti, Laura; Olivieri, Fabiola; Procopio, Antonio Domenico; Tiano, Luca; Rippo, Maria Rita
  3. Aging. 2018, OCT; 10(10): 2855-2873.
  1. 3.   Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Ra mutations
  2. Senkevitch, Emilee; Li, Wenqing; Hixon, Julie; Andrews, Caroline; Cramer, Sarah D; Pauly, Gary; Back, Tim; Czarra, Kelli; Durum, Scott
  3. Oncotarget. 2018, Apr 27; 9(32): 22605-22617.
  1. 4.   One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent
  2. Romagnoli, R.; Baraldi, P. G.; Cara, C. L.; Salvador, M. K.; Bortolozzi, R.; Basso, G.; Viola, G.; Balzarini, J.; Brancale, A.; Fu, X. H.; Li, J.; Zhang, S. Z.; Hamel, E.
  3. European Journal of Medicinal Chemistry. 2011, Dec; 46(12): 6015-6024.
  1. 5.   A Dual-Readout F(2) Assay That Combines Fluorescence Resonance Energy Transfer and Fluorescence Polarization for Monitoring Bimolecular Interactions
  2. Du, Y. H.; Nikolovska-Coleska, Z.; Qui, M.; Li, L.; Lewis, I.; Dingledine, R.; Stuckey, J. A.; Krajewski, K.; Roller, P. P.; Wang, S. M.; Fu, H. A.
  3. Assay and Drug Development Technologies. 2011, Aug; 9(4): 382-393.
  1. 6.   Insulin-like growth factor 1 receptor antibody induces rhabdomyosarcoma cell death via a process involving AKT and Bcl-x(L)
  2. Mayeenuddin, L. H.; Yu, Y.; Kang, Z.; Helman, L. J.; Cao, L.
  3. Oncogene. 2010, Dec; 29(48): 6367-6377.
  1. 7.   Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents
  2. Romagnoli, R.; Baraldi, P. G.; Cara, C. L.; Hamel, E.; Basso, G.; Bortolozzi, R.; Viola, G.
  3. European Journal of Medicinal Chemistry. 2010, Dec; 45(12): 5781-5791.
  1. 8.   Synthesis and in vitro Evaluation of 3H-Pyrrolo[3,2-f]quinolin-9-one Derivatives That Show Potent and Selective Anti-leukemic Activity
  2. Ferlin, M. G.; Bortolozzi, R.; Brun, P.; Castagliuolo, I.; Hamel, E.; Basso, G.; Viola, G.
  3. Chemmedchem. 2010, Jul; 5(8): 1373-1385.
  1. 9.   Interleukin-7 Regulates Bim Proapoptotic Activity in Peripheral T-Cell Survival
  2. Li, W. Q.; Guszczynski, T.; Hixon, J. A.; Durum, S. K.
  3. Molecular and Cellular Biology. 2010, Feb; 30(3): 590-600.
  1. 10.   The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo
  2. Lucas, D. M.; Edwards, R. B.; Lozanski, G.; West, D. A.; Shin, J. D.; Vargo, M. A.; Davis, M. E.; Rozewski, D. M.; Johnson, A. J.; Su, B. N.; Goettl, V. M.; Heerema, N. A.; Lin, T. S.; Lehman, A.; Zhang, X. L.; Jarjoura, D.; Newman, D. J.; Byrd, J. C.
  3. Blood. 2009 113(19): 4656-4666.
  1. 11.   Histone Deacetylase Inhibitors Prevent p53-Dependent and p53-Independent Bax-Mediated Neuronal Apoptosis through Two Distinct Mechanisms
  2. Uo, T.; Veenstra, T. D.; Morrison, R. S.
  3. Journal of Neuroscience. 2009 29(9): 2824-2832.
  1. 12.   CB694, a novel antimitotic with antitumor activities
  2. Weiderhold, K. N.; Randall-Hiubek, D. A.; Polin, L. A.; Hamel, E.; Mooberry, S. L
  3. International Journal of Cancer. 2006, FEB 15; 118(4): 1032-1040.
  1. 13.   Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
  2. Yu, Q.; Park, J. H.; Doan, L. L.; Erman, B.; Feigenbaum, L.; Singer, A.
  3. Journal of Experimental Medicine. 2006, JAN 23; 203(1): 165-175.
  1. 14.   WMC-79, a potent agent against colon cancers, induces apoptosis through a p53-dependent pathway
  2. Kosakowska-Cholody, T.; Cholody, W. M.; Monks, A.; Woynarowska, B. A.; Michejda, C. J.
  3. Molecular Cancer Therapeutics. 2005, OCT; 4(10): 1617-1627.
  1. 15.   Effect of EBV LMP1 targeted DNAzymes on cell proliferation and apoptosis
  2. Lu, Z. X.; Ye, M.; Yan, G. R.; Li, Q.; Tang, M.; Lee, L. M.; Sun, L. Q.; Cao, Y.
  3. Cancer Gene Therapy. 2005, JUL; 12(7): 647-654.
  1. 16.   Cytokine-driven cell cycling is mediated through Cdc25A
  2. Khaled, A. R.; Bulavin, D. V.; Kittipatarin, C.; Li, W. Q.; Alvarez, M.; Kim, K.; Young, H. A.; Fornace, A. J.; Durum, S. K.
  3. Journal of Cell Biology. 2005, JUN 6; 169(5): 755-763.
  1. 17.   IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and ROR gamma t: Impact on thymocyte development
  2. Yu, Q.; Erman, B.; Park, J. H.; Feigenbaum, L.; Singer, A.
  3. Journal of Experimental Medicine. 2004, SEP 20; 200(6): 797-803.
  1. 19.   IL-7 induces tyrosine phosphorylation of clathrin heavy chain
  2. Jiang, Q.; Benbernou, N.; Chertov, O.; Khaled, A. R.; Wooters, J.; Durum, S. K.
  3. Cellular Signalling. 2004 16(2): 281-286.
  1. 20.   Bax translocation and mitochondrial fragmentation induced by Helicobacter pylori
  2. Ashktorab, H.; Frank, S.; Khaled, A. R.; Durum, S. K.; Kifle, B.; Smoot, D. T.
  3. Gut. 2004 53(6): 805-813.
  1. 21.   Differential response of murine CD4(+)CD25(+) and CD4(+)CD25(-) T cells to dexamethasone-induced cell death
  2. Chen, X.; Murakami, T.; Oppenheim, J. J.; Howard, D. M. Z.
  3. European Journal of Immunology. 2004 34(3): 859-869.
  1. 23.   Solution conformations of wild-type and mutated Bak BH3 peptides via dynamical conformational sampling and implication to their binding to antiapoptotic Bcl-2 proteins
  2. Yang, C. Y.; Nikolovska-Coleska, Z.; Li, P.; Roller, P.; Wang, S. M.
  3. Journal of Physical Chemistry B. 2004 108(4): 1467-1477.
  1. 24.   Apo cytochrome c inhibits caspases by preventing apoptosome formation
  2. Martin, A. G.; Nguyen, J.; Wells, J. A.; Fearnhead, H. O.
  3. Biochemical and Biophysical Research Communications. 2004 319(3): 944-950.
  1. 25.   Unaltered expression of Bcl-2 and TAG-1/axonin-1 precedes sensory apoptosis in Brn3a knockout mice
  2. Eng, S. R.; Koziov, S.; Turner, E. E.
  3. Neuroreport. 2003 14(2): 173-176.
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