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  1. 1.   Phase II study of vemurafenib in children and young adults with tumors harboring BRAF V600 mutations: NCI-COG pediatric MATCH trial (APEC1621) Arm G
  2. Nelson, Marie V; Kim, AeRang; Williams,Mickey; Roy-Chowdhuri, Sinchita; Patton, David R; Coffey, Brent D; Reid, Joel M; Piao, Jin; Saguilig, Lauren; Alonzo, Todd A; Berg, Stacey L; Ramirez, Nilsa C; Jaju, Alok; Fox, Elizabeth; Weigel, Brenda J; Hawkins, Douglas S; Mooney, Margaret M; Takebe, Naoko; Tricoli, James V; Janeway, Katherine A; Seibel, Nita L; Parsons, D Williams
  3. The Oncologist. 2024, Jun 14;
  1. 2.   Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier
  2. Thomas, Joanna R; Frye, William J E; Robey, Robert W; Warner,Andrew; Butcher,Donna; Matta,Jennifer; Morgan,Tamara; Edmondson,Elijah; Salazar, Paula B; Ambudkar, Suresh V; Gottesman, Michael M
  3. Fluids and Barriers of the CNS. 2024, Mar 15; 21(1): 27.
  1. 3.   RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation
  2. Smith,Russell; Terrell,Elizabeth; Insinna, Christine; Agamasu, Constance; Wagner, Morgan E; Ritt,Daniel; Stauffer,Jimmy; Stephen,Andy; Morrison,Deborah
  3. Molecular Cell. 2022, Nov 17; 82(22): 4262-4276.
  1. 4.   Embryonic hyperglycemia perturbs the development of specific retinal cell types, including photoreceptors
  2. Titialii-Torres,Kayla; Morris, Ann C
  3. Journal of Cell Science. 2021, Dec 1;
  1. 5.   Myelination induces axonal hotspots of synaptic vesicle fusion that promote sheath growth
  2. Almeida, Rafael G; Williamson, Jill M; Madden, Megan E; Early, Jason J; Voas,Matthew; Talbot, William S; Bianco, Isaac H; Lyons, David A
  3. Current biology : CB. 2021, Sep 13; 31(17): 3743-3754.e5.
  1. 6.   B-Raf autoinhibition in the presence and absence of 14-3-3
  2. Zhang,Mingzhen; Jang,Hyunbum; Li, Zhigang; Sacks, David B.; Nussinov,Ruth
  3. Structure. 2021, Jul 1; 29(7): 768-777.e2.
  1. 7.   Dabrafenib and Trametinib in Patients With Tumors With BRAFV600E Mutations: Results of the NCI-MATCH Trial Subprotocol H
  2. Salama, April K S; Li, Shuli; Macrae, Erin R; Park, Jong-In; Mitchell, Edith P; Zwiebel, James A; Chen, Helen X; Gray, Robert J; McShane, Lisa M; Rubinstein, Larry V; Patton, David; Williams,Mickey; Hamilton, Stanley R; Armstrong, Deborah K; Conley, Barbara A; Arteaga, Carlos L; Harris, Lyndsay N; O'Dwyer, Peter J; Chen, Alice P; Flaherty, Keith T
  3. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020, NOV 20; 38(33): JCO2000762.
  1. 8.   Does Ras Activate Raf and PI3K Allosterically?
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. Frontiers in oncology. 2019, Nov 15; 9
  1. 9.   Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases
  2. Kondo, Yasushi; Ognjenovic,Jana; Banerjee, Saikat; Karandur, Deepti; Merk,Alan; Kulhanek, Kayla; Wong, Kathryn; Roose, Jeroen P.; Subramaniam, Sriram; Kuriyan, John
  3. SCIENCE. 2019, OCT 4; 366(6461): 109-+.
  1. 10.   Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness
  2. Boufraqech, Myriem; Patel, Dhaval; Nilubol, Naris; Powers, Astin; King, Timothy; Shell, Jasmine; Lack,Justin; Zhang, Lisa; Gara, Sudheer Kumar; Gunda, Viswanath; Klubo-Gwiezdzinska, Joanna; Kumar, Suresh; Fagin, James; Knauf, Jeffrey; Parangi, Sareh; Venzon, David; Quezado, Martha; Kebebew, Electron
  3. THYROID. 2019, Jan 1; 29(1): 79-92.
  1. 11.   Allosteric activation of RAF in the MAPK signaling pathway
  2. Tsai,Chung-Jung; Nussinov,Ruth
  3. CURRENT OPINION IN STRUCTURAL BIOLOGY. 2018, Dec; 53: 100-106.
  1. 12.   Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma
  2. Kawaguchi, Kei; Higuchi, Takashi; Li, Shukuan; Han, Qinghong; Tan, Yuying; Igarashi, Kentaro; Zhao, Ming; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Ohshiro, Hiromichi; Sugisawa, Norihiko; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Eckardt, Mark A; Singh, Arun S; Singh, Shree Ram; Eilber, Fritz C; Unno, Michiaki; Hoffman, Robert M
  3. Biochemical and Biophysical Research Communications. 2018, Sep 18; 503(4): 3086-3092.
  1. 13.   Loci associated with skin pigmentation identified in African populations
  2. Crawford, Nicholas G.; Kelly, Derek E.; Hansen, Matthew E. B.; Beltrame, Marcia H.; Fan, Shaohua; Bowman, Shanna L.; Jewett, Ethan; Ranciaro, Alessia; Thompson, Simon; Lo, Yancy; Pfeifer, Susanne P.; Jensen, Jeffrey D.; Campbell, Michael C.; Beggs, William; Hormozdiari, Farhad; Mpoloka, Sununguko Wata; Mokone, Gaonyadiwe George; Nyambo, Thomas; Meskel, Dawit Wolde; Belay, Gurja; Haut, Jake; Rothschild, Harriet; Zon, Leonard; Zhou, Yi; Kovacs, Michael A.; Xu, Mai; Zhang, Tongwu; Bishop, Kevin; Sinclair, Jason; Rivas, Cecilia; Elliot, Eugene; Choi, Jiyeon; Li, Shengchao; Hicks, Belynda; Burgess, Shawn; Abnet, Christian; Watkins-Chow, Dawn E.; Oceana, Elena; Song, Yun S.; Eskin, Eleazar; Brown, Kevin M.; Marks, Michael S.; Loftus, Stacie K.; Pavan, William J.; Yeager, Meredith; Chanock, Stephen; Tishkoff, Sarah A.
  3. Science. 2017, Nov 17; 358(6365): pii: eaan8433.
  1. 14.   KIT Suppresses BRAF(V600E)-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling
  2. Neiswender, James V.; Kortum, Robert L.; Bourque, Caitlin; Kasheta, Melissa; Zon, Leonard I.; Morrison, Deborah; Ceol, Craig J.
  3. Cancer Research. 2017, Nov 01; 77(21): 5820-5830.
  1. 15.   The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning
  2. Zhang, Z.; O'Rourke, J. R.; McManus, M. T.; Lewandoski, M.; Harfe, B. D.; Sun, X.
  3. Developmental Biology. 2011, Mar; 351(2): 254-265.
  1. 16.   A Novel Wilms Tumor 1 (WT1) Target Gene Negatively Regulates the WNT Signaling Pathway
  2. Kim, M. S.; Yoon, S. K.; Bollig, F.; Kitagaki, J.; Hur, W.; Whye, N. J.; Wu, Y. P.; Rivera, M. N.; Park, J. Y.; Kim, H. S.; Malik, K.; Bell, D. W.; Englert, C.; Perantoni, A. O.; Lee, S. B.
  3. Journal of Biological Chemistry. 2010, May; 285(19): 14585-14593.
  1. 17.   Impact of Feedback Phosphorylation and Raf Heterodimerization on Normal and Mutant B-Raf Signaling
  2. Ritt, D. A.; Monson, D. M.; Specht, S. I.; Morrison, D. K.
  3. Molecular and Cellular Biology. 2010, Feb; 30(3): 806-819.
  1. 18.   Defining and Mapping Mammalian Coat Pattern Genes: Multiple Genomic Regions Implicated in Domestic Cat Stripes and Spots
  2. Eizirik, E.; David, V. A.; Buckley-Beason, V.; Roelke, M. E.; Schaffer, A. A.; Hannah, S. S.; Narfstrom, K.; O'Brien, S. J.; Menotti-Raymond, M.
  3. Genetics. 2010, Jan; 184(1): 267-U422.
  1. 19.   Mapping of the Domestic Cat "SILVER" Coat Color Locus Identifies a Unique Genomic Location for Silver in Mammals
  2. Menotti-Raymond, M.; David, V. A.; Eizirik, E.; Roelke, M. E.; Ghaffari, H.; O'Brien, S. J.
  3. Journal of Heredity. 2009 100: S8-S13.
  1. 20.   Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation
  2. Therapontos, C.; Erskine, L.; Gardner, E. R.; Figg, W. D.; Vargesson, N.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(21): 8573-8578.
  1. 21.   Evolution of the vertebrate ABC gene family: Analysis of gene birth and death
  2. Annilo, T.; Chen, Z. Q.; Shulenin, S.; Costantino, J.; Thomas, L.; Lou, H.; Stefanov, S.; Dean, M.
  3. Genomics. 2006, Jul; 88(1): 1-11.
  1. 22.   The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours
  2. Youngren, K. K.; Coveney, D.; Peng, X. N.; Bhattacharya, C.; Schmidt, L. S.; Nickerson, M. L.; Lamb, B. T.; Deng, J. M.; Behringer, R. R.; Capel, B.; Rubin, E. M.; Nadeau, J. H.; Matin, A.
  3. Nature. 2005, MAY 19; 435(7040): 360-364.
  1. 23.   Involvement of domain II in toxicity of anthrax lethal factor
  2. Liang, X. D.; Young, J. J.; Boone, S. A.; Waugh, D. S.; Duesbery, N. S.
  3. Journal of Biological Chemistry. 2004, DEC 10; 279(50): 52473-52478.
  1. 24.   Cancer - Enzymes play molecular tag
  2. Morrison, D. K.
  3. Nature. 2004 428(6985): 813-815.
  1. 25.   Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by delta
  2. Itoh, M.; Kim, C. H.; Palardy, G.; Oda, T.; Jiang, Y. J.; Maust, D.; Yeo, S. Y.; Lorick, K.; Wright, G. J.; Ariza-McNaughton, L.; Weissman, A. M.; Lewis, J.; Chandrasekharappa, S. C.; Chitnis, A. B.
  3. Developmental Cell. 2003 4(1): 67-82.
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