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  1. 1.   Inhibition of Nonfunctional Ras
  2. Nussinov,Ruth; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Gaponenko, Vadim
  3. Cell Chemical Biology. 2021, Feb 18; 28(2): 121-133.
  1. 2.   A new precision medicine initiative at the dawn of exascale computing
  2. Nussinov,Ruth; Jang,Hyunbum; Nir, Guy; Tsai,Chung-Jung; Cheng, Feixiong
  3. Signal transduction and targeted therapy. 2021, Jan 6; 6(1):
  1. 3.   Prolonged mitosis results in structurally aberrant and over-elongated centrioles
  2. Kong,Dong; Sahabandu, Natalie; Sullenberger,Catherine; Vásquez-Limeta, Alejandra; Luvsanjav,Delgermaa; Lukasik,Kimberly; Loncarek,Jadranka
  3. The Journal of cell biology. 2020, Jun 01; 219(6): pii: 151638.
  1. 4.   Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond
  2. Zhao, Bo; Tsai,Yien Che; Jin, Bo; Wang, Bufan; Wang, Yiyang; Zhou, Han; Carpenter, Tomaya; Weissman,Allan; Yin, Jun
  3. Pharmacological reviews. 2020, Apr; 72(2): 380-413.
  1. 5.   Regulation of senescence and the SASP by the transcription factor C/EBP beta
  2. Salotti,Jacqueline; Johnson,Peter
  3. Experimental gerontology. 2019, Dec; 128
  1. 6.   Threonine Tyrosine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy
  2. Zheng, Lin; Chen, Zibo; Kawakami, Masanori; Chen, Yulong; Roszik, Jason; Mustachio, Lisa Maria; Kurie, Jonathan M; Villalobos, Pamela; Lu, Wei; Behren, Carmen; Mino, Barbara; Solis, Luisa M; Silvester, Jennifer; Thu, Kelsie L; Cescon, David W; Rodriguez-Canales, Jaime; Wistuba, Ignacio I; Mak, Tak W; Liu, Xi; Dmitrovsky,Ethan
  3. Molecular cancer therapeutics. 2019, OCT; 18(10): 1775-1786.
  1. 7.   Cryptotanshinone has curative dual anti-proliferative and immunotherapeutic effects on mouse Lewis lung carcinoma
  2. Liu, Shuo; Han, Zhen; Trivett,Anna; Lin, Hongsheng; Hannifin,Sean; Yang,De; Oppenheim,Joost
  3. Cancer immunology, immunotherapy : CII. 2019, JUL; 68(7): 1059-1071.
  1. 8.   BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation
  2. Zong, Dali; Adam, Salome; Wang, Yifan; Sasanuma, Hiroyuki; Callen, Elsa; Murga, Matilde; Day, Amanda; Kruhlak, Michael J.; Wong, Nancy; Munro, Meagan; Chaudhuri, Arnab Ray; Karim,Baktiar; Xia, Bing; Takeda, Shunichi; Johnson, Neil; Durocher, Daniel; Nussenzweig, Andre
  3. Molecular cell. 2019, MAR 21; 73(6): 1267-+.
  1. 9.   High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy
  2. Bowler, Mathew; Kong, Dong; Sun, Shufeng; Nanjundappa, Rashmi; Evans, Lauren; Farmer, Veronica; Holland, Andrew; Mahjoub, Moe R.; Sui, Haixin; Loncarek, Jadranka
  3. Nature communications. 2019, Mar 1; 10(1): 993.
  1. 10.   A New View of Pathway-Driven Drug Resistance in Tumor Proliferation
  2. Nussinov, Ruth; Tsai, Chung-Jung; Jang, Hyunbum
  3. TRENDS IN PHARMACOLOGICAL SCIENCES. 2017, May; 38(5): 427-437.
  1. 11.   The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation
  2. von Eyss, B.; Maaskola, J.; Memczak, S.; Mollmann, K.; Schuetz, A.; Loddenkemper, C.; Tanh, M. D.; Otto, A.; Muegge, K.; Heinemann, U.; Rajewsky, N.; Ziebold, U.
  3. Embo Journal. 2012, Feb; 31(4): 972-985.
  1. 12.   Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155
  2. Chang, S. H.; Wang, R. H.; Akagi, K.; Kim, K. A.; Martin, B. K.; Cavallone, L.; Haines, D. C.; Basik, M.; Mai, P.; Poggi, E.; Isaacs, C.; Looi, L. M.; Mun, K. S.; Greene, M. H.; Byers, S. W.; Teo, S. H.; Deng, C. X.; Sharan, S. K.; Kathleen Cuningham Fdn, C.
  3. Nature Medicine. 2011, Oct; 17(10): 1275-U308.
  1. 13.   SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity
  2. Kim, H. S.; Vassilopoulos, A.; Wang, R. H.; Lahusen, T.; Xiao, Z.; Xu, X. L.; Li, C. L.; Veenstra, T. D.; Li, B.; Yu, H. T.; Ji, J. F.; Wang, X. W.; Park, S. H.; Cha, Y. I.; Gius, D.; Deng, C. X.
  3. Cancer Cell. 2011, Oct; 20(4): 487-499.
  1. 14.   Synthesis and Anticancer Activity of 13-Membered Cyclic Enediynes
  2. Sharma, M.; Joshi, M. C.; Kumar, V.; Malhotra, S. V.; Rawat, D. S.
  3. Archiv Der Pharmazie. 2011, Sep; 344(9): 564-571.
  1. 15.   The tumour suppressor C/EBP delta inhibits FBXW7 expression and promotes mammary tumour metastasis
  2. Balamurugan, K.; Wang, J. M.; Tsai, H. H.; Sharan, S.; Anver, M.; Leighty, R.; Sterneck, E.
  3. Embo Journal. 2010, Dec; 29(24): 4106-4117.
  1. 16.   Development of a Validated Immunofluorescence Assay for gamma H2AX as a Pharmacodynamic Marker of Topoisomerase I Inhibitor Activity
  2. Kinders, R. J.; Hollingshead, M.; Lawrence, S.; Ji, J. P.; Tabb, B.; Bonner, W. M.; Pommier, Y.; Rubinstein, L.; Evrard, Y. A.; Parchment, R. E.; Tomaszewski, J.; Doroshow, J. H.; Natl Canc Inst Phase 0 Clinical, T.
  3. Clinical Cancer Research. 2010, Nov; 16(22): 5447-5457.
  1. 17.   Defining the Molecular Nexus of Cancer, Type 2 Diabetes and Cardiovascular Disease
  2. Cabarcas, S. M.; Hurt, E. M.; Farrar, W. L.
  3. Current Molecular Medicine. 2010, Nov; 10(8): 741-755.
  1. 18.   Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria
  2. Hernandez, L.; Roux, K. J.; Wong, E. S. M.; Mounkes, L. C.; Mutalif, R.; Navasankari, R.; Rai, B.; Cool, S.; Jeong, J. W.; Wang, H. H.; Lee, H. S.; Kozlov, S.; Grunert, M.; Keeble, T.; Jones, C. M.; Meta, M. D.,; Young, S. G.; Daar, I. O.; Burke, B.; Perantoni, A. O.; Stewart, C. L.
  3. Developmental Cell. 2010, Sep 14; 19(3): 413-425.
  1. 19.   Polo-box domain: a versatile mediator of polo-like kinase function
  2. Park, J. E.; Soung, N. K.; Johmura, Y.; Kang, Y. H.; Liao, C.; Lee, K. H.; Park, C. H.; Nicklaus, M. C.; Lee, K. S.
  3. Cellular and Molecular Life Sciences. 2010, Jun; 67(12): 1957-1970.
  1. 20.   C/EBP ? targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression
  2. Pawar, S. A.; Sarkar, T. R.; Balamurugan, K.; Sharan, S.; Wang, J.; Zhang, Y. H.; Dowdy, S. F.; Huang, A. M.; Sterneck, E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2010, May 18; 107(20): 9210-9215.
  1. 21.   Schizosaccharomyces pombe Dss1p Is a DNA Damage Checkpoint Protein That Recruits Rad24p, Cdc25p, and Rae1p to DNA Double-strand Breaks
  2. Selvanathan, S. P.; Thakurta, A. G.; Dhakshnamoorthy, J.; Zhou, M.; Veenstra, T. D.; Dhar, R.
  3. Journal of Biological Chemistry. 2010, May; 285(19): 14122-14133.
  1. 22.   A dual role of Cdk2 in DNA damage response
  2. Satyanarayana, A.; Kaldis, P.
  3. Cell Division. 2009, May; 4: 4.
  1. 23.   Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G(1)/S transition
  2. Li, W.; Kotoshiba, S.; Berthet, C.; Hilton, M. B.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(2): 486-491.
  1. 24.   Cdk2 and Cdk4 Activities Are Dispensable for Tumorigenesis Caused by the Loss of p53
  2. Padmakumar, V. C.; Aleem, E.; Berthet, C.; Hilton, M. B.; Kaldis, P.
  3. Molecular and Cellular Biology. 2009 29(10): 2582-2593.
  1. 25.   Ras(V12)-Mediated Down-regulation of CCAAT/Enhancer Binding Protein beta in Immortalized Fibroblasts Requires Loss of p19(Arf) and Facilitates Bypass of Oncogene-Induced Senescence
  2. Sebastian, T.; Johnson, P. F.
  3. Cancer Research. 2009 69(6): 2588-2598.
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