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  1. 1.   Combinatorial screen with apoptosis pathway targeted agents alrizomadlin, pelcitoclax, and dasminapant in multi-cell type tumor spheroids
  2. Coussens,Nathan; Dexheimer,Thomas; Silvers,Thomas; Sanchez,Phillip; Chen,Li; Hollingshead, Melinda G; Takebe, Naoko; Doroshow, James H; Teicher, Beverly A
  3. SLAS Discovery : advancing life sciences R & D. 2025, Apr 08; 100230.
  1. 2.   Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids
  2. Dexheimer,Tom; Davoudi,Zahra; Coussens,Nathan; Silvers,Thomas; Morris, Joel; Takebe, Naoko; Said, Rabih; Moscow, Jeffrey A; Doroshow, James H; Teicher, Beverly A
  3. SLAS Discovery : advancing life sciences R & D. 2025, Feb 23; 100222.
  1. 3.   Combination screen in multi-cell type tumor spheroids reveals interaction between aryl hydrocarbon receptor antagonists and E1 ubiquitin-activating enzyme inhibitor: Aryl-hydrocarbon receptor antagonist drug combinations
  2. Dexheimer,Tom; Coussens,Nathan; Silvers,Thomas; Jones,Eric; Chen,Lily; Fang, Jianwen; Morris, Joel; Moscow, Jeffrey A; Doroshow, James H; Teicher, Beverly A
  3. SLAS Discovery : advancing life sciences R & D. 2024, Oct 01; 29(7): 100186.
  1. 4.   Second-generation checkpoint inhibitors and Treg depletion synergize with a mouse cancer vaccine in accordance with tumor microenvironment characterization
  2. Becker, William; Olkhanud, Purevdorj B; Seishima, Noriko; Moreno, Paloma A; Goldfarbmuren,Kate; Maeng, Hoyoung M; Berzofsky, Jay A
  3. Journal for Immunotherapy of Cancer. 2024, Jul 01; 12(7):
  1. 5.   Combinational delivery of TLR4 and TLR7/8 agonist enhanced the therapeutic efficacy of immune checkpoint inhibitors to colon tumor
  2. Wang, Mengjiao; Wan, Quan; Wang, Chenglv; Jing, Qianyu; Nie, Yujie; Zhang, Xiangyan; Chen, Xin; Yang,De; Pan, Runsang; Li, Linzhao; Zhu, Lan; Gui, Huan; Chen, Shuanghui; Deng, Yuezhen; Chen, Tao; Nie, Yingjie
  3. Molecular and Cellular Biochemistry. 2024, Mar 20;
  1. 6.   Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors
  2. Mittra, Arjun; Coyne, Geraldine H O' Sullivan; Zlott, Jennifer; Kummar, Shivaani; Meehan, Robert; Rubinstein, Lawrence; Juwara,Lamin; Wilsker,Deborah; Ji,Jay; Miller,Brandon; Navas, Tony; Ferry-Galow,Katherine; Voth,Andrea; Chang,Ting-Chia; Jiwani,Shahanawaz; Parchment,Ralph; Doroshow, James H; Chen, Alice P
  3. Cancer Chemotherapy and Pharmacology. 2023, Nov 27;
  1. 7.   Development of a bicistronic anti-CD19/CD20 CAR construct including abrogation of unexpected nucleic acid sequence deletions
  2. Lam, Norris; Finney, Richard; Yang, Shicheng; Choi, Stephanie; Wu,Xiaolin; Cutmore, Lauren; Andrade, Jorge; Huang, Lei; Amatya, Christina; Cam, Margaret; Kochenderfer, James N
  3. Molecular Therapy Oncolytics. 2023, Sep 21; 30: 132-149.
  1. 8.   Recombineering: Genetic Engineering in Escherichia coli Using Homologous Recombination
  2. Thomason,Lynn; Costantino, Nina; Li, Xintian; Court,Don
  3. Current Protocols. 2023, Feb; 3(2): e656.
  1. 9.   Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans
  2. Bashirova,Arman; Kasprzak,Wojciech; Ohuigin,Colm; Carrington,Mary
  3. Immunogenetics. 2022, Nov 30;
  1. 10.   Adaptation of HIV-1/HIV-2 Chimeras with Defects in Genome Packaging and Viral Replication
  2. Rawson, Jonathan M O; Nikolaitchik,Olga; Yoo, Jennifer A; Somoulay, Xayathed; Brown, Matthew A; Mbuntcha Bogni, Franck S; Pathak,Vinay; Soheilian,Ferri; Slack, Ryan L; Sarafianos, Stefan G; Hu,Wei-Shau
  3. mBio. 2022, Aug 29; e0222022.
  1. 11.   WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells
  2. Datta, Arindam; Biswas, Kajal; Sommers, Joshua A.; Thompson, Haley; Awate, Sanket; Nicolae, Claudia M.; Thakar, Tanay; Moldovan, George-Lucian; Shoemaker, Robert H.; Sharan, Shyam K.; Brosh, Robert M.
  3. Nature Communications. 2021, Nov 12; 12(1):
  1. 12.   Adcitmer(R), a new CD56-targeting monomethyl auristatin E-conjugated antibody, is a potential therapeutic approach in Merkel cell carcinoma
  2. Esnault, C.; Martin, C.; Desgranges, A.; Baltus, C. B.; Aubrey, N.; Lakhrif, Z.; Lajoie, L.; Lantier, L.; Clemenceau, B.; Sarma, B.; Schrama, J.; Houben, R.; Schrama, D.; Hesbacher, S.; Feng,Yang; Dimitrov, D.; Guyetant, S.; Berthon, P.; Viaud-Massuard, M. C.; Samimi, M.; Touze, A.; Kervarrec, T.
  3. The British Journal of Dermatology. 2021, Sep 28;
  1. 13.   Recent advances in nanoparticles mediated photothermal therapy induced tumor regression
  2. Kumar, Achalla Vaishnav Pavan; Dubey, Sunil K.; Tiwari, Sanjay; Puri,Anu; Hejmady, Siddhanth; Gorain, Bapi; Kesharwani, Prashant
  3. International Journal of Pharmaceutics. 2021, Sep 5; 606
  1. 14.   The dystonia gene THAP1 controls DNA double-strand break repair choice
  2. Shinoda, Kenta; Zong, Dali; Callen, Elsa; Wu, Wei; Dumitrache, Lavinia C.; Belinky, Frida; Chari,Raj; Wong, Nancy; Ishikawa, Momoko; Stanlie, Andre; Multhaupt-Buell, Trisha; Sharma, Nutan; Ozelius, Laurie; Ehrlich, Michelle; McKinnon, Peter J.; Nussenzweig, Andre
  3. MOLECULAR CELL. 2021, Jun 17; 81(12): 2611-2624.e10.
  1. 15.   CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice
  2. Li, Nan; Torres, Madeline B.; Spetz, Madeline R.; Wang, Ruixue; Peng, Luyi; Tian, Meijie; Dower, Christopher M.; Nguyen, Rosa; Sun, Ming; Tai, Chin-Hsien; de Val, Natalia; Cachau,Raul; Wu, Xiaolin; Hewitt, Stephen M.; Kaplan, Rosandra N.; Khan, Javed; St Croix,Brad; Thiele, Carol J.; Ho, Mitchell
  3. Cell reports. Medicine. 2021, Jun 15; 2(6):
  1. 16.   A study of transposable element-associated structural variations (TASVs) using a de novo-assembled Korean genome
  2. Mun, Seyoung; Kim, Songmi; Lee, Wooseok; Kang, Keunsoo; Meyer,Thomas; Han, Bok-Ghee; Han, Kyudong; Kim, Heui-Soo
  3. Experimental and Molecular Medicine. 2021, Apr; 53(4): 615-630.
  1. 17.   Virus Evolution and Neutralization Sensitivity in an HIV-1 Subtype B ' Infected Plasma Donor with Broadly Neutralizing Activity
  2. Hu, Yuanyuan; Zou, Sen; Wang, Zheng; Liu, Ying; Ren, Li; Hao, Yanling; Sun, Shasha; Hu, Xintao; Ruan, Yuhua; Ma, Liying; Shao, Yiming; Hong, Kunxue
  3. Vaccines. 2021, Apr; 9(4):
  1. 18.   Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment
  2. Wheeler, David A; Takebe, Naoko; Hinoue, Toshinori; Hoadley, Katherine A; Cardenas, Maria F; Hamilton, Alina M; Laird, Peter W; Wang, Linghua; Johnson, Adrienne; Dewal, Ninad; Miller, Vincent; Piñeyro, David; Castro de Moura, Manuel; Esteller, Manel; Shen, Hui; Zenklusen, Jean Claude; Tarnuzzer, Roy; McShane, Lisa M; Tricoli, James V; Williams, Paul M; Lubensky, Irina; O'Sullivan-Coyne, Geraldine; Kohn, Elise C; Little, Richard F; White, Jeffrey; Malik, Shakun; Harris, Lyndsay; Weil, Carol; Chen, Alice P; Karlovich,Chris; Rodgers, Brian; Shankar, Lalitha; Jacobs, Paula; Nolan, Tracy; Hu, Jianhong; Muzny, Donna M; Doddapaneni, Harshavardhan; Korchina, Viktoriya; Gastier-Foster, Julie; Bowen, Jay; Leraas, Kristen; Edmondson,Elijah; Doroshow, James H; Conley, Barbara A; Ivy, S Percy; Staudt, Louis M
  3. Cancer Cell. 2021, Jan 11; 39(1): 38-53.e7.
  1. 19.   A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays
  2. Biswas,Kajal; Lipton, Gary B; Stauffer,Stacey; Sullivan,Teresa; Cleveland, Linda; Southon,Eileen; Reid,Susan; Magidson,Valentin; Iversen, Edwin S; Sharan,Shyam
  3. NPJ genomic medicine. 2020, Dec 08; 5(1): 52.
  1. 20.   Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas
  2. Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Meehan, Robert S; Do, Khanh; Collins, Jerry M; Anderson, Larry; Ishii, Kazusa; Takebe, Naoko; Zlott, Jennifer; Juwara,Lamin; Piekarz, Richard; Streicher, Howard; Sharon, Elad; Rubinstein, Larry; Voth,Andrea; Lozier, Jay; Dull,Angie; Wilsker,Deborah; Hinoue, Toshinori; Laird, Peter W; Ferry-Galow,Katherine; Kinders,Robert; Parchment,Ralph; Doroshow,Jim; Chen, Alice P
  3. Oncotarget. 2020, Nov 03; 11(44): 3959-3971.
  1. 21.   Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination
  2. He,Yafeng; Ren,Jianke; Xu,Xiaoping; Ni,Kai; Schwader, Andrew; Finney, Richard; Wang, Can; Sun, Lei; Klarmann, Kimberly; Keller,Jonathan; Tubbs, Anthony; Nussenzweig, Andre; Muegge, Kathrin
  3. Proceedings of the National Academy of Sciences of the United States of America. 2020, AUG 18; 117(33): 20100-20108.
  1. 22.   Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model
  2. Philippou, Yiannis; Sjoberg, Hanna T.; Murphy, Emma; Alyacoubi, Said; Jones, Keaton I.; Gordon-Weeks, Alex N.; Phyu, Su; Parkes, Eileen E.; Gillies McKenna, W.; Lamb, Alastair D.; Gileadi, Uzi; Cerundolo, Vincenzo; Scheiblin,David; Lockett,Stephen; Wink,David; Mills, Ian G.; Hamdy, Freddie C.; Muschel, Ruth J.; Bryant, Richard J.
  3. BRITISH JOURNAL OF CANCER. 2020, JUL 9;
  1. 23.   Dual infection and recombination of Kaposi sarcoma herpesvirus revealed by whole-genome sequence analysis of effusion samples
  2. Cornejo Castro,Elena; Marshall,Vickie; Lack,Justin; Lurain, Kathryn; Immonen,Taina; Labo,Nazzarena; Fisher, Nicholas C; Ramaswami, Ramya; Polizzotto, Mark N; Keele,Brandon; Yarchoan, Robert; Uldrick, Thomas S; Whitby,Denise
  3. Virus Evolution. 2020, Jul; 6(2): veaa047.
  1. 24.   Recombinant Methioninase Combined With Tumor-targeting Salmonella typhimurium A1-R Induced Regression in a PDOX Mouse Model of Doxorubicin-resistant Dedifferentiated Liposarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Zhao, Ming; Han, Qinghong; Tan, Yuying; Kiyuna, Tasuku; Miyake, Kentaro; Higuchi, Takashi; Nelson, Scott D; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2515-2523.
  1. 25.   An analytical pipeline for identifying and mapping the integration sites of HIV and other retroviruses
  2. Wells,Daria; Guo,Amber; Shao,Wei; Bale,Michael; Coffin, John M; Hughes,Stephen; Wu,Xiaolin
  3. BMC genomics. 2020, Mar 09; 21(1): 216.
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