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  1. 1.   Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors
  2. Zhao, Xue Zhi; Smith, Steven; Maskell, Daniel P.; Metifiot, Mathieu; Pye, Valerie E.; Fesen, Katherine; Marchand, Christophe; Pommier, Yves; Cherepanov, Peter; Hughes, Stephen; Burke, Terrence
  3. Journal of Medicinal Chemistry. 2017, SEP 14; 60(17): 7315-7332.
  1. 2.   Molecular Dynamics Approaches Estimate the Binding Energy of HIV-1 Integrase Inhibitors and Correlate with In Vitro Activity
  2. Johnson, B. C.; Metifiot, M.; Pommier, Y.; Hughes, S. H.
  3. Antimicrobial Agents and Chemotherapy. 2012, Jan; 56(1): 411-419.
  1. 3.   Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A
  2. Witvrouw, M.; Fikkert, V.; Hantson, A.; Pannecouque, C.; O'Keefe, B. R.; McMahon, J.; Stamatatos, L.; De Clercq, E.; Bolmstedt, A.
  3. Journal of Virology. 2005, JUN; 79(12): 7777-7784.
  1. 4.   Cross-resistance of Escherichia coli RNA polymerases conferring rifarnpin resistance to different antibiotics
  2. Xu, M.; Zhou, Y. N.; Goldstein, B. P.; Jin, D. J.
  3. Journal of Bacteriology. 2005, APR; 187(8): 2783-2792.
  1. 5.   Efficacy of PLD-118, a novel inhibitor of Candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and Esophageal candidiasis caused by fluconazole-resistant C albicans
  2. Petraitis, V.; Petraitiene, R.; Kelaher, A. M.; Sarafandi, A. A.; Sein, T.; Mickiene, D.; Bacher, J.; Groll, A. H.; Walsh, T. J.
  3. Antimicrobial Agents and Chemotherapy. 2004, OCT; 48(10): 3959-3967.
  1. 6.   Effect of sequence polymorphism and drug resistance on two HIV- 1 Gag processing sites
  2. Feher, A.; Weber, I. T.; Bagossi, P.; Boross, P.; Mahalingam, B.; Louis, J. M.; Copeland, T. D.; Torshin, I. Y.; Harrison, R. W.; Tozser, J.
  3. European Journal of Biochemistry. 2002 269(16): 4114-4120.
  1. 7.   A potent human immunodeficiency virus type 1 protease inhibitor, UIC-94003 (TMC-126), and selection of a novel (A28S) mutation in the protease active site
  2. Yoshimura, K.; Kato, R.; Kavlick, M. F.; Nguyen, A.; Maroun, V.; Maeda, K.; Hussain, K. A.; Ghosh, A. K.; Gulnik, S. V.; Erickson, J. W.; Mitsuya, H.
  3. Journal of Virology. 2002 76(3): 1349-1358.
  1. 8.   Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells
  2. Honjo, Y.; Hrycyna, C. A.; Yan, Q. W.; Medina-Perez, W. Y.; Robey, R. W.; van de Laar, A.; Litman, T.; Dean, M.; Bates, S. E.
  3. Cancer Research. 2001 61(18): 6635-6639.
  1. 9.   Structural studies of FIV and HIV-1 proteases complexed with all efficient inhibitor of FIV protease
  2. Li, M.; Morris, G. M.; Lee, T.; Laco, G. S.; Wong, C. H.; Olson, A. J.; Elder, J. H.; Wlodawer, A.; Gustchina, A.
  3. Proteins. 2000 38(1): 29-40.
  1. 10.   HIV protease: Enzyme function and drug resistance
  2. Gulnik, S.; Erickson, J. W.; Xie, D.
  3. Vitamins and Hormones - Advances in Research and Applications, Vol 58. 2000 58: 213-256.
  1. 11.   Hiv Type 1 Protease Inhibitors Fail to Inhibit Htlv-I Gag Processing in Infected Cells
  2. Pettit, S. C.; Sanchez, R.; Smith, T.; Wehbie, R.; Derse, D.; Swanstrom, R.
  3. Aids Research and Human Retroviruses. 1998 14(11): 1007-1014.
  1. 12.   Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 angstrom resolution
  2. Ding, J. P.; Das, K.; Hsiou, Y.; Sarafianos, S. G.; Clark, A. D.; Jacobo-Molina, A.; Tantillo, C.; Hughes, S. H.; Arnold, E.
  3. Journal of Molecular Biology. 1998 284(4): 1095-1111.
  1. 13.   A cooperative folding unit in HIV-1 protease. Implications for protein stability and occurrence of drug-induced mutations
  2. Wallqvist, A.; Smythers, G. W.; Covell, D. G.
  3. Protein Engineering. 1998 11(11): 999-1005.
  1. 14.   Structural Analysis of Inhibitor Binding to Hiv-1 Protease - Identification of a Common Binding Motif
  2. Covell, D. G.; Jernigan, R. L.; Wallqvist, A.
  3. Theochem-Journal of Molecular Structure. 1998 423(1-2): 93-100.
  1. 15.   2'-Fluoro-2',3'-Dideoxyarabinosyladenine (F-Dda) - Activity Against Drug-Resistant Human Immunodeficiency Virus Strains and Clades a-E
  2. Driscoll, J. S.; Mayers, D. L.; Bader, J. P.; Weislow, O. S.; Johns, D. G.; Buckheit, R. W.
  3. Antiviral Chemistry & Chemotherapy. 1997 8(2): 107-111.
  1. 16.   Increased Lrp Mrna Expression Is Associated With the Mdr Phenotype in Intrinsically Resistant Human Cancer Cell Lines
  2. Laurencot, C. M.; Scheffer, G. L.; Scheper, R. J.; Shoemaker, R. H.
  3. International Journal of Cancer. 1997 72(6): 1021-1026.
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