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  1. 1.   Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells
  2. Hwang, S. K.; Minai-Tehrani, A.; Yu, K. N.; Chang, S. H.; Kim, J. E.; Lee, K. H.; Park, J.; Beck, G. R.; Cho, M. H.
  3. International Journal of Oncology. 2012, May; 40(5): 1515-1524.
  1. 2.   JS-K, a Glutathione S-Transferase-Activated Nitric Oxide Donor With Antineoplastic Activity in Malignant Gliomas
  2. Weyerbrock, A.; Osterberg, N.; Psarras, N.; Baumer, B.; Kogias, E.; Werres, A.; Bette, S.; Saavedra, J. E.; Keefer, L. K.; Papazoglou, A.
  3. Neurosurgery. 2012, Feb; 70(2): 497-510.
  1. 3.   One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3 ',4 ',5 '-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent
  2. Romagnoli, R.; Baraldi, P. G.; Cara, C. L.; Salvador, M. K.; Bortolozzi, R.; Basso, G.; Viola, G.; Balzarini, J.; Brancale, A.; Fu, X. H.; Li, J.; Zhang, S. Z.; Hamel, E.
  3. European Journal of Medicinal Chemistry. 2011, Dec; 46(12): 6015-6024.
  1. 4.   Insulin-like growth factor 1 receptor antibody induces rhabdomyosarcoma cell death via a process involving AKT and Bcl-x(L)
  2. Mayeenuddin, L. H.; Yu, Y.; Kang, Z.; Helman, L. J.; Cao, L.
  3. Oncogene. 2010, Dec; 29(48): 6367-6377.
  1. 5.   Synthesis and Antitumor Activity of 1,5-Disubstituted 1,2,4-Triazoles as Cis-Restricted Combretastatin Analogues
  2. Romagnoli, R.; Baraldi, P. G.; Cruz-Lopez, O.; Cara, C. L.; Carrion, M. D.; Brancale, A.; Hamel, E.; Chen, L. C.; Bortolozzi, R.; Basso, G.; Viola, G.
  3. Journal of Medicinal Chemistry. 2010, May; 53(10): 4248-4258.
  1. 6.   The C-terminal transmembrane domain of Bcl-x(L) mediates changes in mitochondrial morphology
  2. Zheng, J. Y.; Tsai, Y. C.; Kadimcherla, P.; Zhang, R.; Shi, J.; Oyler, G. A.; Boustany, N. N.
  3. Biophysical Journal. 2008 94(1): 286-297.
  1. 7.   Caspase-dependent cleavage disrupts the ERK cascade scaffolding function of KSR1
  2. McKay, M. M.; Morrison, D. K.
  3. Journal of Biological Chemistry. 2007, Sep; 282(36): 26225-26234.
  1. 8.   Data mining of NCI's anticancer screening database reveals mitochondrial complex I inhibitors cytotoxic to leukemia cell lines
  2. Glover, C. J.; Rabow, A. A.; Isgor, Y. G.; Shoemaker, R. H.; Covell, D. G.
  3. Biochemical Pharmacology. 2007, Feb; 73(3): 331-340.
  1. 9.   Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis
  2. Hu, C. A. A.; Donald, S. P.; Yu, J.; Lin, W. W.; Liu, Z. H.; Steel, G.; Obie, C.; Valle, D.; Phang, J. M.
  3. Molecular and Cellular Biochemistry. 2007, Jan; 295(1-2): 85-92.
  1. 10.   Small molecule inhibitors of Apaf-1-related caspase-3/-9 activation that control mitochondrial-dependent apoptosis
  2. Malet, G.; Martin, A. G.; Orzaez, M.; Vicent, M. J.; Masip, I.; Sanclimens, G.; Ferrer-Montiel, A.; Mingarro, I.; Messeguer, A.; O Fearnhead, H.; Perez-Paya, E.
  3. Cell Death and Differentiation. 2006, Sep; 13(9): 1523-1532.
  1. 11.   Intracellular nucleotides act as critical prosurvival factors by binding to cyctochrome c and inhibiting apoptosome
  2. Chandra, D.; Bratton, S. B.; Person, M. D.; Tian, Y. A.; Martin, A. G.; Ayres, M.; Fearnhead, H. O.; Gandhi, V.; Tang, D. G.
  3. Cell. 2006, Jun; 125(7): 1333-1346.
  1. 12.   HIV gp41-induced apoptosis is mediated by caspase-3-dependent mitochondrial depolarization, which is inhibited by HIV protease inhibitor nelfinavir
  2. Garg, H.; Blumenthal, R.
  3. Journal of Leukocyte Biology. 2006, Feb; 79(2): 351-362.
  1. 13.   Multicolor fluorescence-based approaches for imaging cytokine-induced alterations in the neovascularization, growth, metastasis, and apoptosis of murine neuroblastoma tumors
  2. Stauffer, J. K.; Khan, T.; Salcedo, R.; Hixon, J. A.; Lincoln, E.; Back, T. C.; Wigginton, J. M.
  3. Journal of Immunotherapy. 2006, MAR-APR; 29(2): 151-164.
  1. 14.   Effect of EBV LMP1 targeted DNAzymes on cell proliferation and apoptosis
  2. Lu, Z. X.; Ye, M.; Yan, G. R.; Li, Q.; Tang, M.; Lee, L. M.; Sun, L. Q.; Cao, Y.
  3. Cancer Gene Therapy. 2005, JUL; 12(7): 647-654.
  1. 15.   Induction of apoptosis by flavopiridol in human neuroblastoma cells is enhanced under hypoxia and associated with N-myc proto-oncogene down-regulation
  2. Puppo, M.; Pastorino, S.; Melillo, G.; Pezzolo, A.; Varesio, L.; Bosco, M. C.
  3. Clinical Cancer Research. 2004, DEC 15; 10(24): 8704-8719.
  1. 16.   Marine pharmacology in 2001-2: antitumour and cytotoxic compounds
  2. Mayer, A. M. S.; Gustafson, K. R.
  3. European Journal of Cancer. 2004, DEC; 40(18): 2676-2704.
  1. 17.   BCL-x(L)-dependent light scattering by apoptotic cells
  2. Boustany, N. N.; Tsai, Y. C.; Pfister, B.; Joiner, W. M.; Oyler, G. A.; Thakor, N. V.
  3. Biophysical Journal. 2004, DEC; 87(6): 4163-4171.
  1. 18.   JS-K, a novel nitric oxide (NO) generator, induces cytochrome c release and caspase activation in HL-60 myeloid leukemia cells
  2. Shami, P. J.; Udupi, V.; Yu, M.; Malaviya, S.; Saavedra, J. E.; Keefer, L. K.
  3. Blood. 2004, NOV 16; 104(11, Part 1, Abstract 3415): 931A-931A.
  1. 19.   Caspase-mediated apoptosis and caspase-independent cell death induced by irofulven in prostate cancer cells
  2. Liang, H. Y.; Salinas, R. A.; Leal, B. Z.; Kosakowska-Cholody, T.; Michejda, C. J.; Waters, S. J.; Herman, T. S.; Woynarowski, J. M.; Woynarowska, B. A.
  3. Molecular Cancer Therapeutics. 2004, NOV; 3(11): 1385-1396.
  1. 20.   Components of the cell death machine and drug sensitivity of the National Cancer Institute cell line panel
  2. Svingen, P. A.; Loegering, D.; Rodriquez, J.; Meng, X. W.; Mesner, P. W.; Holbeck, S.; Monks, A.; Krajewski, S.; Scudiero, D. A.; Sausville, E. A.; Reed, J. C.; Lazebnik, Y. A.; Kaufmann, S. H.
  3. Clinical Cancer Research. 2004, OCT 15; 10(20): 6807-6820.
  1. 21.   Getting back on track, or what to do when apoptosis is de-railed - Recoupling oncogenes to the apoptotic machinery
  2. Fearnhead, H. O.
  3. Cancer Biology & Therapy. 2004 3(1): 21-28.
  1. 22.   Bax translocation and mitochondrial fragmentation induced by Helicobacter pylori
  2. Ashktorab, H.; Frank, S.; Khaled, A. R.; Durum, S. K.; Kifle, B.; Smoot, D. T.
  3. Gut. 2004 53(6): 805-813.
  1. 23.   Apo cytochrome c inhibits caspases by preventing apoptosome formation
  2. Martin, A. G.; Nguyen, J.; Wells, J. A.; Fearnhead, H. O.
  3. Biochemical and Biophysical Research Communications. 2004 319(3): 944-950.
  1. 24.   Relationship between ion pair geometries and electrostatic strengths in proteins
  2. Kumar, S.; Nussinov, R.
  3. Biophysical Journal. 2002 83(3): 1595-1612.
  1. 25.   Expression of Bcl-2 family member bid in normal and malignant tissues
  2. Krajewska, M.; Zapata, J. M.; Meinhold-Heerlein, I.; Hedayat, H.; Monks, A.; Bettendorf, H.; Shabaik, A.; Bubendorf, L.; Kallioniemi, O. P.; Kim, H.; Reifenberger, G.; Reed, J. C.; Krajewski, S.
  3. Neoplasia. 2002 4(2): 129-140.
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