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  1. 1.   MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Lwin, Thinzar M; Miyake, Masuyo; Kiyuna, Tasuku; Hwang, Ho Kyoung; Murakami, Takashi; Delong, Jonathan C; Singh, Shree Ram; Clary, Bryan; Bouvet, Michael; Unno, Michiaki; Hoffman, Robert M
  3. Tissue & cell. 2018, Jun; 52: 124-128.
  1. 2.   Inhibition of ABCG2-mediated drug efflux by naphthopyrones from marine crinoids
  2. Bokesch, H. R.; Cartner, L. K.; Fuller, R. W.; Wilson, J. A.; Henrich, C. J.; Kelley, J. A.; Gustafson, K. R.; McMahon, J. B.; McKee, T. C.
  3. Bioorganic & Medicinal Chemistry Letters. 2010, Jul; 20(13): 3848-3850.
  1. 3.   Pharmacogenetics of Membrane Transporters: An Update on Current Approaches
  2. Sissung, T. M.; Baum, C. E.; Kirkl, C. T.; Gao, R.; Gardner, E. R.; Figg, W. D.
  3. Molecular Biotechnology. 2010, Feb; 44(2): 152-167.
  1. 4.   Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib
  2. Gardner, E. R.; Burger, H.; van Schaik, R. H.; van Oosterom, A. T.; de Bruijn, E. A.; Guetens, G.; Prenen, H.; de Jong, F. A.; Baker, S. D.; Bates, S. E.; Figg, W. D.; Verweij, J.; Sparreboom, A.; Nooter, K.
  3. Clinical Pharmacology & Therapeutics. 2006, Aug; 80(2): 192-201.
  1. 5.   A high-throughput cell-based assay for inhibitors of ABCG2 activity
  2. Henrich, C. J.; Bokesch, H. R.; Dean, M.; Bates, S. E.; Robey, R. W.; Goncharova, E. I.; Wilson, J. A.; McMahon, J. B.
  3. Journal of Biomolecular Screening. 2006, Mar; 11(2): 176-183.
  1. 6.   Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells
  2. Honjo, Y.; Hrycyna, C. A.; Yan, Q. W.; Medina-Perez, W. Y.; Robey, R. W.; van de Laar, A.; Litman, T.; Dean, M.; Bates, S. E.
  3. Cancer Research. 2001 61(18): 6635-6639.
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