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  1. 1.   CDK2 Inhibition Produces a Persistent Population of Polyploid Cancer Cells
  2. Tyutyunyk-Massey, Liliya; Chen,Zibo; Liu,Xiuxia; Kawakami, Masanori; Harned,Adam; Ng, Yeap; Harned,Adam; Okpechi,Samuel; Ogunlade,Blessing; Alfaro Mora,Yair; Weigert, Roberto; Narayan,Kedar; Liu,Xi; Dmitrovsky,Ethan
  3. JCI Insight. 2025, Apr 15;
  1. 2.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 3.   Slower CDK4 and faster CDK2 activation in the cell cycle
  2. Zhang,Wengang; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Structure (London, England : 1993). 2024, Apr 23;
  1. 4.   Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae
  2. Nielipinski, Maciej; Pietrzyk-Brzezinska, Agnieszka J; Wlodawer,Alexander; Sekula, Bartosz
  3. Frontiers in Plant Science. 2023, Dec 18; 14: 1297956.
  1. 5.   Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B
  2. Muys, Bruna R; Shrestha, Roshan L; Anastasakis, Dimitrios G; Pongor, Lorinc; Li, Xiao Ling; Grammatikakis, Ioannis; Polash, Ahsan; Chari,Raj; Gorospe, Myriam; Harris, Curtis C; Aladjem, Mirit I; Basrai, Munira A; Hafner, Markus; Lal, Ashish
  3. Cell Reports. 2023, Mar 15; 42(3): 112260.
  1. 6.   Context-Dependent Function of Long Noncoding RNA PURPL in Transcriptome Regulation during p53 Activation
  2. Hartford, Corrine Corrina R; Shrestha, Roshan L; Pongor, Lorinc; Zhao,Yongmei; Chen, Xiongfong; Fromont,Caroline; Chaudhary, Ritu; Li, Xiao Ling; Pasterczyk, Katherine R; Kumar, Ravi; Muys, Bruna R; Tsitsipatis, Dimitrios; Chari,Raj; Gorospe, Myriam; Aladjem, Mirit I; Khan, Javed; Basrai, Munira A; Grammatikakis, Ioannis; Lal, Ashish
  3. Molecular and Cellular Biology. 2022, Nov 07; 42(12): e0028922.
  1. 7.   Restoration of microRNA metabolism trigger robust antitumor responses
  2. Bofill De Ros,Xavier
  3. Molecular Therapy. Nucleic Acids. 2022, Sep 13; 29: 498-500.
  1. 8.   Direct anabolic metabolism of three carbon propionate to a six carbon metabolite occurs in vivo across tissues and species
  2. Doan, Mary T; Neinast, Michael D; Varner, Erika L; Bedi, Kenneth; Bartee,David; Jiang, Helen; Trefely, Sophie; Xu, Peining; Singh, Jay P; Jang, Cholsoon; Rame, Eduardo; Brady, Donita; Meier,Jordan; Marguiles, Kenneth; Arany, Zoltan; Snyder, Nathaniel W
  3. Journal of Lipid Research. 2022, May 11; 63(6): 100224.
  1. 9.   Inhibition of Nonfunctional Ras
  2. Nussinov,Ruth; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Gaponenko, Vadim
  3. Cell Chemical Biology. 2021, Feb 18; 28(2): 121-133.
  1. 10.   Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors
  2. Spano, Virginia; Barreca, Marilia; Rocca, Roberta; Bortolozzi, Roberta; Bai, Ruoli; Carbone, Anna; Raimondi, Maria Valeria; Piccionello, Antonio Palumbo; Montalbano, Alessandra; Alcaro, Stefano; Hamel, Ernest; Viola, Giampietro; Barraja, Paola
  3. European Journal of Medicinal Chemistry. 2021, Feb 15; 212
  1. 11.   RAB19 Directs Cortical Remodeling and Membrane Growth for Primary Ciliogenesis
  2. Jewett, Cayla E.; Soh, Adam W. J.; Lin, Carrie H.; Lu,Quanlong; Lencer, Ezra; Westlake,Christopher; Pearson, Chad G.; Prekeris, Rytis
  3. Developmental Cell. 2021, Feb 8; 56(3): 325-340.e8.
  1. 12.   A new precision medicine initiative at the dawn of exascale computing
  2. Nussinov,Ruth; Jang,Hyunbum; Nir, Guy; Tsai,Chung-Jung; Cheng, Feixiong
  3. Signal transduction and targeted therapy. 2021, Jan 6; 6(1):
  1. 13.   Overproduction of a dominant mutant of the conserved Era GTPase inhibits cell division in Escherichia coli
  2. Zhou, Xiaomei; Peters, Howard K; Li,Xintian; Costantino,Nina; Kumari,Vandana; Shi,Genbin; Tu, Chao; Cameron, Todd A; Haeusser, Daniel P; Vega, Daniel E; Ji, Xinhua; Margolin, William; Court,Don
  3. Journal of bacteriology. 2020, NOV; 202(21): pii: JB.00342-20.
  1. 14.   Metabolic characterization of aggressive breast cancer cells exhibiting invasive phenotype: impact of non-cytotoxic doses of 2-DG on diminishing invasiveness
  2. Fujita, Mayumi; Imadome, Kaori; Somasundaram,Veena; Kawanishi, Miki; Karasawa, Kumiko; Wink,David
  3. BMC cancer. 2020, Sep 29; 20(1): 929.
  1. 15.   Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite
  2. Perez,Minervo; Bak, Daniel W.; Bergholtz, Sarah E.; Crooks, Daniel R.; Arimilli, Bhargav Srinivas; Yang, Youfeng; Weerapana, Eranthie; Linehan, W. Marston; Meier,Jordan
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, SEP 25; 295(39): 13410-13418.
  1. 16.   Impact of losing hRpn13 Pru or UCHL5 on proteasome clearance of ubiquitinated proteins and RA190 cytotoxicity
  2. Osei Amponsa,Vasty; Sridharan, Vinidhra; Tandon,Mayank; Evans,Christine; Klarmann,Kim; Cheng,Oscar; Lack,Justin; Chari,Raj; Walters,Kylie
  3. Molecular and cellular biology. 2020, SEP; 40(18):
  1. 17.   Prolonged mitosis results in structurally aberrant and over-elongated centrioles
  2. Kong,Dong; Sahabandu, Natalie; Sullenberger,Catherine; Vásquez-Limeta, Alejandra; Luvsanjav,Delgermaa; Lukasik,Kimberly; Loncarek,Jadranka
  3. The Journal of cell biology. 2020, Jun 01; 219(6): pii: 151638.
  1. 18.   Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond
  2. Zhao, Bo; Tsai,Yien Che; Jin, Bo; Wang, Bufan; Wang, Yiyang; Zhou, Han; Carpenter, Tomaya; Weissman,Allan; Yin, Jun
  3. Pharmacological reviews. 2020, Apr; 72(2): 380-413.
  1. 19.   Regulation of senescence and the SASP by the transcription factor C/EBP beta
  2. Salotti,Jacqueline; Johnson,Peter
  3. Experimental gerontology. 2019, Dec; 128
  1. 20.   Threonine Tyrosine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy
  2. Zheng, Lin; Chen, Zibo; Kawakami, Masanori; Chen, Yulong; Roszik, Jason; Mustachio, Lisa Maria; Kurie, Jonathan M; Villalobos, Pamela; Lu, Wei; Behren, Carmen; Mino, Barbara; Solis, Luisa M; Silvester, Jennifer; Thu, Kelsie L; Cescon, David W; Rodriguez-Canales, Jaime; Wistuba, Ignacio I; Mak, Tak W; Liu, Xi; Dmitrovsky,Ethan
  3. Molecular cancer therapeutics. 2019, OCT; 18(10): 1775-1786.
  1. 21.   Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility
  2. Stavreva, Diana A; Garcia, David A; Fettweis, Gregory; Gudla, Prabhakar R; Zaki,George; Soni, Vikas; McGowan, Andrew; Williams, Geneva; Huynh, Anh; Palangat, Murali; Schiltz, R Louis; Johnson, Thomas A; Presman, Diego M; Ferguson, Matthew L; Pegoraro, Gianluca; Upadhyaya, Arpita; Hager, Gordon L
  3. Molecular cell. 2019, SEP 19; 75(6): 1161-+.
  1. 22.   Cryptotanshinone has curative dual anti-proliferative and immunotherapeutic effects on mouse Lewis lung carcinoma
  2. Liu, Shuo; Han, Zhen; Trivett,Anna; Lin, Hongsheng; Hannifin,Sean; Yang,De; Oppenheim,Joost
  3. Cancer immunology, immunotherapy : CII. 2019, JUL; 68(7): 1059-1071.
  1. 23.   BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation
  2. Zong, Dali; Adam, Salome; Wang, Yifan; Sasanuma, Hiroyuki; Callen, Elsa; Murga, Matilde; Day, Amanda; Kruhlak, Michael J.; Wong, Nancy; Munro, Meagan; Chaudhuri, Arnab Ray; Karim,Baktiar; Xia, Bing; Takeda, Shunichi; Johnson, Neil; Durocher, Daniel; Nussenzweig, Andre
  3. Molecular cell. 2019, MAR 21; 73(6): 1267-+.
  1. 24.   High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy
  2. Bowler, Mathew; Kong, Dong; Sun, Shufeng; Nanjundappa, Rashmi; Evans, Lauren; Farmer, Veronica; Holland, Andrew; Mahjoub, Moe R.; Sui, Haixin; Loncarek, Jadranka
  3. Nature communications. 2019, Mar 1; 10(1): 993.
  1. 25.   Comparison of vaccination with rhesus CMV (RhCMV) soluble gB with a RhCMV replication-defective virus deleted for MHC class I immune evasion genes in a RhCMV challenge model
  2. Valencia, Sarah; Gill, Rachel B.; Dowdell, Kennichi C.; Wang,Yanmei; Hornung, Ron; Bowman, J. Jason; Lacayo, Juan C.; Cohen, Jeffrey I.
  3. Vaccine. 2019, Jan 7; 37(7): 333-342.
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