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  1. 1.   A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity
  2. Makhaik, Sparsh; Rut, Wioletta; Choudhary, Shruti; Upadhyay, Tulsi; Hao, Chenzhou; Westberg, Michael; Bobst, Cedric; Yoo,Euna; Fejzo, Jasna; Lin, Michael Z; Bogyo, Matthew; Thompson, Paul; Drag, Marcin; Hardy, Jeanne A
  3. Protein Science : a publication of the Protein Society. 2025, Mar; 34(3): e70069.
  1. 2.   SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
  2. Ohara, Yuuki; Tang, Wei; Liu, Huaitian; Yang, Shouhui; Dorsey, Tiffany H; Cawley, Helen; Moreno, Paloma; Chari,Raj; Guest,Mary; Azizian, Azadeh; Gaedcke, Jochen; Ghadimi, Michael; Hanna, Nader; Ambs, Stefan; Hussain, S Perwez
  3. Cell Reports. 2023, Nov 18; 42(12): 113434.
  1. 3.   RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation
  2. Smith,Russell; Terrell,Elizabeth; Insinna, Christine; Agamasu, Constance; Wagner, Morgan E; Ritt,Daniel; Stauffer,Jimmy; Stephen,Andy; Morrison,Deborah
  3. Molecular Cell. 2022, Nov 17; 82(22): 4262-4276.
  1. 4.   The mechanism of Raf activation through dimerization
  2. Zhang,Mingzhen; Maloney,Ryan; Jang,Hyunbum; Nussinov,Ruth
  3. Chemical Science. 2021, Dec 08; 12(47): 15609-15619.
  1. 5.   B-Raf autoinhibition in the presence and absence of 14-3-3
  2. Zhang,Mingzhen; Jang,Hyunbum; Li, Zhigang; Sacks, David B.; Nussinov,Ruth
  3. Structure. 2021, Jul 1; 29(7): 768-777.e2.
  1. 6.   Inhibition of Nonfunctional Ras
  2. Nussinov,Ruth; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Gaponenko, Vadim
  3. Cell Chemical Biology. 2021, Feb 18; 28(2): 121-133.
  1. 7.   Anionic Lipids Impact RAS-Binding Site Accessibility and Membrane Binding Affinity of CRAF RBD-CRD
  2. Travers, Timothy; López, Cesar A; Agamasu, Constance; Hettige, Jeevapani J; Messing,Simon; García, Angel E; Stephen, Andrew G; Gnanakaran, S
  3. Biophysical journal. 2020, AUG 4; 119(3): 525-538.
  1. 8.   The Mystery of Rap1 Suppression of Oncogenic Ras
  2. Nussinov,Ruth; Jang,Hyunbum; Zhang,Mingzhen; Tsai,Chung-Jung; Sablina, Anna A.
  3. Trends in cancer. 2020, May; 6(5): 369-379.
  1. 9.   Stable and Potent Selenomab-Drug Conjugates
  2. Li, Xiuling; Nelson, Christopher; Nair, Rajesh R; Hazlehurst, Lori; Moroni, Tina; Martinez-Acedo, Pablo; Nanna, Alex R; Hymel, David; Burke, Terrence; Rader, Christoph
  3. Cell Chemical Biology. 2017, Apr 20; 24(4): 433-442.
  1. 10.   Modulation of Liver L-gamma-Glutamyl-L-cysteinylglycine Homeostasis By N-Acetyl-Glucosamine-thiazolidine-4(R)-carboxylic Acid in Mice
  2. Liu, J.; Cai, W. D.; Liu, W. S.; Han, B. Q.; Chang, J.; Yang, Y.
  3. American Journal of the Medical Sciences. 2012, Apr; 343(4): 310-315.
  1. 11.   Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells
  2. He, S.; Wang, J. N.; Kato, K.; Xie, F.; Varambally, S.; Mineishi, S.; Kuick, R.; Mochizuki, K.; Liu, Y. N. A.; Nieves, E.; Mani, R. S.; Chinnaiyan, A. M.; Marquez, V. E.; Zhang, Y.
  3. Blood. 2012, Feb; 119(5): 1274-1282.
  1. 12.   Histone Deacetylase Inhibitors from Burkholderia thailandensis
  2. Klausmeyer, P.; Shipley, S. M.; Zuck, K. M.; McCloud, T. G.
  3. Journal of Natural Products. 2011, Oct; 74(10): 2039-2044.
  1. 13.   Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model
  2. Fu, T. M.; Almqvist, J.; Liang, Y. H.; Li, L. F.; Huang, Y. F.; Su, X. D.
  3. Journal of Molecular Biology. 2011, Sep; 412(4): 688-697.
  1. 14.   Sulfiredoxin-Peroxiredoxin IV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling
  2. Wei, Q. O.; Jiang, H.; Xiao, Z.; Baker, A.; Young, M. R.; Veenstra, T. D.; Colburn, N. H.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2011, Apr; 108(17): 7004-7009.
  1. 15.   A further insight into the sialome of the tropical bont tick, Amblyomma variegatum
  2. Ribeiro, J. M. C.; Anderson, J. M.; Manoukis, N. C.; Meng, Z. J.; Francischetti, I. M. B.
  3. Bmc Genomics. 2011, Mar; 12: 11.
  1. 16.   Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration
  2. Wirth, E. K.; Conrad, M.; Winterer, J.; Wozny, C.; Carlson, B. A.; Roth, S.; Schmitz, D.; Bornkamm, G. W.; Coppola, V.; Tessarollo, L.; Schomburg, L.; Kohrle, J.; Hatfield, D. L.; Schweizer, U.
  3. Faseb Journal. 2010, Mar; 24(3): 844-852.
  1. 17.   Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin
  2. Klamt, F.; Zdanov, S.; Levine, R. L.; Pariser, A.; Zhang, Y. Q.; Zhang, B. L.; Yu, L. R.; Veenstra, T. D.; Shacter, E.
  3. Nature Cell Biology. 2009 11(10): 1241-U193.
  1. 18.   Structure Mechanism Insights and the Role of Nitric Oxide Donation Guide the Development of Oxadiazole-2-Oxides as Therapeutic Agents against Schistosomiasis
  2. Rai, G.; Sayed, A. A.; Lea, W. A.; Luecke, H. F.; Chakrapani, H.; Prast-Nielsen, S.; Jadhav, A.; Leister, W.; Shen, M.; Inglese, J.; Austin, C. P.; Keefer, L.; Arner, E.; Simeonov, A.; Maloney, D. J.; Williams, D. L.; Thomas, C. J.
  3. Journal of Medicinal Chemistry. 2009 52(20): 6474-6483.
  1. 19.   MTHFR genotype and colorectal adenoma recurrence: Data from a double-blind placebo-controlled clinical trial
  2. Levine, A. J.; Wallace, K.; Tsang, S.; Haile, R. W.; Saibil, F.; Ahnen, D.; Cole, B. F.; Barry, E. L.; Munroe, D. J.; Ali, I. U.; Uel, P.; Baron, J. A.
  3. Cancer Epidemiology Biomarkers & Prevention. 2008 17(9): 2409-2415.
  1. 20.   Induction of autophagy in porcine kidney cells by quantum dots: A common cellular response to nanomaterials?
  2. Stern, S. T.; Zolnik, B. S.; McLel, C. B.; Clogston, J.; Zheng, J. W.; McNeil, S. E.
  3. Toxicological Sciences. 2008 106(1): 140-152.
  1. 21.   Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies
  2. Wei, Q.; Jiang, H.; Matthews, C. P.; Colburn, N. H.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2008 105(50): 19738-19743.
  1. 22.   Decreased selenoprotein expression alters the immune response during influenza virus infection in mice
  2. Sheridan, P. A.; Zhong, N. X.; Carlson, B. A.; Perella, C. M.; Hatfield, D. L.; Beck, M. A.
  3. Journal of Nutrition. 2007, Jun; 137(6): 1466-1471.
  1. 23.   A comparative study of the expression of serine proteinases in quiescent seeds and in developing Canavalia ensiformis plants
  2. Demartini, D. R.; Wlodawer, A.; Carlini, C. R.
  3. Journal of Experimental Botany. 2007, Feb; 58(3): 521-532.
  1. 24.   Conformationally constrained analogues of diacylglycerol. 26. Exploring the chemical space surrounding the C1 domain of protein kinase C with DAG-lactones containing aryl groups at the sn-1 and sn-2 positions
  2. Kang, J. H.; Benzaria, S.; Sigano, D. M.; Lewin, N. E.; Pu, Y. M.; Peach, M. L.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2006, Jun; 49(11): 3185-3203.
  1. 25.   Inhibition of transcription factor NF-kappa B signaling proteins IKK beta and p65 through specific cysteine residues by epoxyquinone A monomer: Correlation with its anti-cancer cell growth activity
  2. Liang, M. C.; Bardhan, S.; Pace, E. A.; Rosman, D.; Beutler, J. A.; Porco, J. A.; Gilmore, T. D.
  3. Biochemical Pharmacology. 2006, FEB 28; 71(5): 634-645.
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