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  1. 1.   Isolation and Characterization of the CYP2D6 Gene in Felidae with Comparison to Other Mammals
  2. Schenekar, T.; Winkler, K. A.; Troyer, J. L.; Weiss, S.
  3. Journal of Molecular Evolution. 2011, Feb; 72(2): 222-231.
  1. 2.   Efavirenz Induces CYP2B6-Mediated Hydroxylation of Bupropion in Healthy Subjects
  2. Robertson, S. M.; Maldarelli, F.; Natarajan, V.; Formentini, E.; Alfaro, R. M.; Penzak, S. R.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2008 49(5): 513-519.
  1. 3.   Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages
  2. del Sol, A.; Arauzo-Bravo, M. J.; Moya, D. A.; Nussinov, R.
  3. Genome Biology. 2007 8(5):
  1. 4.   Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450
  2. Inami, K.; Nims, R. W.; Srinivasan, A.; Citro, M. L.; Saavedra, J. E.; Cederbaum, A. I.; Keefer, L. K.
  3. Nitric Oxide-Biology and Chemistry. 2006, Jun; 14(4): 309-315.
  1. 5.   Lack of sex-related differences in saquinavir pharmacokinetics in an HIV-seronegative cohort
  2. Robertson, S. M.; Formentini, E.; Alfaro, R. M.; Natarajan, V.; Falloon, J.; Penzak, S. R.
  3. British Journal of Clinical Pharmacology. 2006, Apr; 61(4): 379-388.
  1. 6.   Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: Functional similarity to the human disease and identification of prospective tumoral markers and targets
  2. Urzua, U.; Roby, K. F.; Gangi, L. M.; Cherry, J. M.; Powell, J. I.; Munroe, D. J.
  3. Journal of Cellular Physiology. 2006, MAR; 206(3): 594-602.
  1. 7.   Prednisolone pharmacokinetics in the presence and absence of Ritonavir after oral prednisone administration to healthy volunteers
  2. Penzak, S. R.; Fomnentini, E.; Alfaro, R. M.; Long, M.; Natarajan, V.; Kovacs, J.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2005, DEC 15; 40(5): 573-580.
  1. 8.   Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients
  2. Lepper, E. R.; Baker, S. D.; Permenter, M.; Ries, N.; van Schaik, R. H. N.; Schenk, P. W.; Price, D. K.; Ahn, D.; Smith, N. F.; Cusatis, G.; Ingersoll, R. G.; Bates, S. E.; Mathijssen, R. H. J.; Verweij, J.; Figg, W. D.; Sparreboom, A.
  3. Clinical Cancer Research. 2005, OCT 15; 11(20): 7398-7404.
  1. 9.   Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2
  2. Cheung, C.; Ma, X. C.; Krausz, K. W.; Kimura, S.; Feigenbaum, L.; Dalton, T. P.; Nebert, D. W.; Idle, J. R.; Gonzalez, F. J.
  3. Chemical Research in Toxicology. 2005, SEP; 18(9): 1471-1478.
  1. 10.   CYP1A1 Val(462) and NQO1 Ser(187) polymorphisms, cigarette use, and risk for colorectal adenoma
  2. Hou, L. F.; Chatterjee, N.; Huang, W. Y.; Baccarelli, A.; Yadavalli, S.; Yeager, M.; Bresalier, R. S.; Chanock, S. J.; Caporaso, N. E.; Ji, B. T.; Weissfeld, J. L.; Hayes, R. B.
  3. Carcinogenesis. 2005, JUN; 26(6): 1122-1128.
  1. 11.   The CYP2E1-humanized transgenic mouse: Role of CYP2E1 in acetaminophen hepatotoxicity
  2. Cheung, C.; Yu, A. M.; Ward, J. M.; Krausz, K. W.; Akiyama, T. E.; Feigenbaum, L.; Gonzalez, F. J.
  3. Drug Metabolism and Disposition. 2005, MAR; 33(3): 449-457.
  1. 12.   Fluorinated 2-(4-amino-3-methylphenyl) benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells
  2. Brantley, E.; Trapani, V.; Alley, M. C.; Hose, C. D.; Bradshaw, T. D.; Stevens, M. F. G.; Sausville, E. A.; Stinson, S. F.
  3. Drug Metabolism and Disposition. 2004, DEC; 32(12): 1392-1401.
  1. 13.   Enhanced acetaminophen toxicity by activation of the pregnane X receptor
  2. Guo, G. L.; Moffit, J. S.; Ward, J. M.; Aleksunes, L. A.; Slitt, A. L.; Kliewer, S. A.; Manautou, J. E.; Gonzalez, F. J.
  3. Toxicological Sciences. 2004, DEC; 82(2): 374-380.
  1. 14.   Identification of oxidized mitochondria proteins in alcohol-exposed human hepatoma cells and mouse liver
  2. Suh, S. K.; Hood, B. L.; Kim, B. J.; Conrads, T. P.; Veenstra, T. D.; Song, B. J.
  3. Proteomics. 2004, NOV; 4(11): 3401-3412.
  1. 15.   The experimental antitumor agents Phortress and Doxorubicin are equiactive against human-derived breast carcinoma xenograft models
  2. Fichtner, I.; Monks, A.; Hose, C.; Stevens, M. F. G.; Bradshaw, T. D.
  3. Breast Cancer Research and Treatment. 2004, SEP; 87(1): 97-107.
  1. 16.   Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway
  2. Chen, S. Y.; Lin, J. R. V.; Darbha, R.; Lin, P. P.; Liu, T. Y.; Chen, Y. M. A.
  3. Cancer Research. 2004 64(10): 3617-3623.
  1. 17.   Estrogen signaling in livers of male mice with hepatocellular carcinoma induced by exposure to arsenic in utero
  2. Waalkes, M. P.; Liu, J.; Chen, H.; Xie, Y. X.; Achanzar, W. E.; Zhou, Y. S.; Cheng, M. L.; Diwan, B. A.
  3. Journal of the National Cancer Institute. 2004 96(6): 466-474.
  1. 18.   Aryl hydrocarbon receptor activation of an antitumor aminoflavone: Basis of selective toxicity for MCF-7 breast tumor cells
  2. Loaiza-Perez, A. I.; Kenney, S.; Boswell, J.; Hollingshead, M.; Alley, M. C.; Hose, C.; Ciolino, H. P.; Yeh, G. C.; Trepel, J. B.; Vistica, D. T.; Sausville, E. A.
  3. Molecular Cancer Therapeutics. 2004 3(6): 715-725.
  1. 19.   Dehydroepiandrosterone inhibits the expression of carcinogen- activating enzymes in vivo
  2. Ciolino, H.; MacDonald, C.; Memon, O.; Dankwah, M.; Yeh, G. C.
  3. International Journal of Cancer. 2003 105(3): 321-325.
  1. 20.   Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4- amino-3-methylphenyl]-5-fluoro-benzothiazole: A potential surrogate marker for patient sensitivity
  2. Hose, C. D.; Hollingshead, M.; Sausville, E. A.; Monks, A.
  3. Molecular Cancer Therapeutics. 2003 2(12): 1265-1272.
  1. 21.   Constitutive expression and localization of the major drug metabolizing enzyme, cytochrome P4502D in human brain
  2. Chinta, S. J.; Pai, H. V.; Upadhya, S. C.; Boyd, M. R.; Ravindranath, V.
  3. Molecular Brain Research. 2002 103(1-2): 49-61.
  1. 22.   Toxicological consequences of differential regulation of cytochrome p450 Isoforms in rat brain regions by phenobarbital
  2. Upadhya, S. C.; Chinta, S. J.; Pai, H. V.; Boyd, M. R.; Ravindranath, V.
  3. Archives of Biochemistry and Biophysics. 2002 399(1): 56-65.
  1. 23.   Cytochrome P4502E (CYP2E) in brain: Constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization
  2. Upadhya, S. C.; Tirumalai, P. S.; Boyd, M. R.; Mori, T.; Ravindranath, V.
  3. Archives of Biochemistry and Biophysics. 2000 373(1): 23-34.
  1. 24.   Multiple forms of cytochrome P450 and associated monooxygenase activities in human brain mitochondria
  2. Bhagwat, S. V.; Boyd, M. R.; Ravindranath, V.
  3. Biochemical Pharmacology. 2000 59(5): 573-582.
  1. 25.   CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice
  2. Kimura, S.; Kawabe, M.; Ward, J. M.; Morishima, H.; Kadlubar, F. F.; Hammons, G. J.; Fernandez-Salguero, P.; Gonzalez, F. J.
  3. Carcinogenesis. 1999 20(9): 1825-1830.
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