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  1. 1.   Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer
  2. Furusawa, Takashi; Cavero, Renzo; Liu, Yue; Li, Haojian; Xu,Xia; Andresson,Thorkell; Reinhold, William; White, Olivia; Boufraqech, Myriem; Meyer,Thomas; Hartmann, Oliver; Diefenbacher, Markus E; Pommier, Yves; Weyemi, Urbain
  3. Molecular Carcinogenesis. 2024, Feb 27;
  1. 2.   Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation
  2. Geffen, Yifat; Anand, Shankara; Akiyama, Yo; Yaron, Tomer M; Song, Yizhe; Johnson, Jared L; Govindan, Akshay; Babur, Özgün; Li, Yize; Huntsman, Emily; Wang, Liang-Bo; Birger, Chet; Heiman, David I; Zhang, Qing; Miller, Mendy; Maruvka, Yosef E; Haradhvala, Nicholas J; Calinawan, Anna; Belkin, Saveliy; Kerelsky, Alexander; Clauser, Karl R; Krug, Karsten; Satpathy, Shankha; Payne, Samuel H; Mani, D R; Gillette, Michael A; Dhanasekaran, Saravana M; Thiagarajan,Mathangi; Mesri, Mehdi; Rodriguez, Henry; Robles, Ana I; Carr, Steven A; Lazar, Alexander J; Aguet, François; Cantley, Lewis C; Ding, Li; Getz, Gad
  3. Cell. 2023, Aug 09;
  1. 3.   Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition
  2. Whiteaker, Jeffrey R; Wang, Tao; Zhao, Lei; Schoenherr, Regine M; Kennedy, Jacob J; Voytovich, Ulianna; Ivey, Richard G; Huang, Dongqing; Lin, Chenwei; Colantonio,Simona; Caceres,Tessa; Roberts,Rhonda; Knotts,Joseph; Kaczmarczyk,Jan; Blonder,Josip; Reading,Joshua; Richardson, Christopher W; Hewitt, Stephen M; Garcia-Buntley,Stephanie; Bocik,William; Hiltke, Tara; Rodriguez, Henry; Harrington, Elizabeth A; Barrett, J Carl; Lombardi, Benedetta; Marco-Casanova, Paola; Pierce, Andrew J; Paulovich, Amanda G
  3. Cancers. 2021, Aug; 13(15):
  1. 4.   Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors
  2. Takebe, Naoko; Naqash, Abdul Rafeh; Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Do, Khanh; Bruns, Ashley; Juwara,Lamin; Zlott, Jennifer; Rubinstein, Larry; Piekarz, Richard; Sharon, Elad; Streicher, Howard; Mittra, Arjun; Miller, Sarah B.; Ji,Jay; Wilsker,Deborah; Kinders,Robert; Parchment,Ralph; Chen,Li; Chang,Ting-Chia; Das,Biswajit; Mugundu, Ganesh; Doroshow, James H.; Chen, Alice P.
  3. CLINICAL CANCER RESEARCH. 2021, Apr 16; 27(14): 3834-3844.
  1. 5.   Phosphorylation of SMURF2 by ATM exerts a negative feedback control of DNA damage response
  2. Tang, Liu-Ya; Thomas, Adam; Zhou, Ming; Zhang, Ying E
  3. The Journal of biological chemistry. 2020, Dec 25; 295(52): 18485-18493.
  1. 6.   Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA damage response in Purkinje neuron progenitors
  2. Casoni, Filippo; Croci, Laura; Bosone, Camilla; D'Ambrosio, Roberta; Badaloni, Aurora; Gaudesi, Davide; Barili, Valeria; Sarna, Justyna R; Tessarollo, Lino; Cremona, Ottavio; Hawkes, Richard; Warming, Søren; Consalez, G Giacomo
  3. Development. 2017, Oct 15; 144(20): 3686-3697.
  1. 7.   CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute
  2. Zoppoli, G.; Solier, S.; Reinhold, W. C.; Liu, H.; Connelly, J. W.; Monks, A.; Shoemaker, R. H.; Abaan, O. D.; Davis, S. R.; Meltzer, P. S.; Doroshow, J. H.; Pommier, Y.
  3. Oncogene. 2012, Jan; 31(4): 403-418.
  1. 8.   Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155
  2. Chang, S. H.; Wang, R. H.; Akagi, K.; Kim, K. A.; Martin, B. K.; Cavallone, L.; Haines, D. C.; Basik, M.; Mai, P.; Poggi, E.; Isaacs, C.; Looi, L. M.; Mun, K. S.; Greene, M. H.; Byers, S. W.; Teo, S. H.; Deng, C. X.; Sharan, S. K.; Kathleen Cuningham Fdn, C.
  3. Nature Medicine. 2011, Oct; 17(10): 1275-U308.
  1. 9.   DNA repair: the culprit for tumor-initiating cell survival?
  2. Mathews, L. A.; Cabarcas, S. M.; Farrar, W. L.
  3. Cancer and Metastasis Reviews. 2011, Jun; 30(2): 185-197.
  1. 10.   Epimorphic regeneration in mice is p53-independent
  2. Arthur, L. M.; Demarest, R. M.; Clark, L.; Gourevitch, D.; Bedelbaeva, K.; Anderson, R.; Snyder, A.; Capobianco, A. J.; Lieberman, P.; Feigenbaum, L.; Heber-Katz, E.
  3. Cell Cycle. 2010, Sep; 9(18): 3667-3673.
  1. 11.   Histone yH2AX and Poly(ADP-Ribose) as Clinical Pharmacodynamic Biomarkers
  2. Redon, C. E.; Nakamura, A. J.; Zhang, Y. W.; Ji, J. P.; Bonner, W. M.; Kinders, R. J.; Parchment, R. E.; Doroshow, J. H.; Pommier, Y.
  3. Clinical Cancer Research. 2010, Sep; 16(18): 4532-4542.
  1. 12.   Interleukin-15 Enhances Proteasomal Degradation of Bid in Normal Lymphocytes: Implications for Large Granular Lymphocyte Leukemias
  2. Hodge, D. L.; Yang, J.; Buschman, M. D.; Schaughency, P. M.; Dang, H.; Bere, W.; Yang, Y. L.; Savan, R.; Subleski, J. J.; Yin, X. M.; Loughran, T. P.; Young, H. A.
  3. Cancer Research. 2009 69(9): 3986-3994.
  1. 13.   Targeting the ubiquitin-proteasome system for cancer therapy
  2. Yang, Y. L.; Kitagaki, J.; Wang, H.; Hou, D. X.; Perantoni, A. O.
  3. Cancer Science. 2009 100(1): 24-28.
  1. 14.   Aberrant splicing induced by missense mutations in BRCA1: clues from a humanized mouse model
  2. Yang, Y. P.; Swaminathan, S.; Martin, B. K.; Sharan, S. K.
  3. Human Molecular Genetics. 2003 12(17): 2121-2131.
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