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  1. 1.   Optimization of the PROTAC linker region of the proteasome substrate receptor hRpn13 rationalized structural modeling with molecular dynamics
  2. Lu,Xiuxiu; Sabbasani, Venkata R; Walters,Kylie; Swenson, Rolf E; Walters,Kylie
  3. The Journal of Biological Chemistry. 2025, Apr 18; 108520.
  1. 2.   Discovery of potent and selective PROTACs for the protein kinase LZK for the treatment of head and neck cancer
  2. Katerji,Meghri; Bergman, Knickole L; Lindberg, Eric; Rubin,Maxine; Funk, Amy L; Woodroofe, Carolyn C; Nyswaner, Katherine; Karpinska, Kamila; Serwa, Remigiusz; Marusiak, Anna; Swenson, Rolf E; Brognard,John
  3. The Journal of Biological Chemistry. 2025, Mar 27; 108452.
  1. 3.   Methotrexate-based PROTACs as DHFR-specific chemical probes
  2. Rana, Sandeep; Dranchak, Patricia; Dahlin, Jayme L; Lamy, Laurence; Li,Wenqing; Oliphant, Erin; Shrimp, Jonathan H; Rajacharya, Girish H; Tharakan, Ravi; Holland, David O; Whitten, Apryl S; Wilson, Kelli M; Singh, Pankaj K; Durum,Scott; Tao, Dingyin; Rai, Ganesha; Inglese, James
  3. Cell Chemical Biology. 2023, Oct 17;
  1. 4.   Differential sensitivity of the yeast Lon protease Pim1p to impaired mitochondrial respiration
  2. Metzger,Meredith; Scales, Jessica L; Grant, Garis A; Molnar,Abby; Loncarek,Jadranka; Weissman,Allan
  3. The Journal of Biological Chemistry. 2023, Aug; 299(8): 104937.
  1. 5.   Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
  2. Cable, Jennifer; Weber-Ban, Eilika; Clausen, Tim; Walters,Kylie; Sharon, Michal; Finley, Daniel J.; Gu, Yangnan; Hanna, John; Feng, Yue; Martens, Sascha; Simonsen, Anne; Hansen, Malene; Zhang, Hong; Goodwin, Jonathan M.; Reggio, Alessio; Chang, Chunmei; Ge, Liang; Schulman, Brenda A.; Deshaies, Raymond J.; Dikic, Ivan; Harper, J. Wade; Wertz, Ingrid E.; Thoma, Nicolas H.; Slabicki, Mikolaj; Frydman, Judith; Jakob, Ursula; David, Della C.; Bennett, Eric J.; Bertozzi, Carolyn R.; Sardana, Richa; Eapen, Vinay V.; Carra, Serena
  3. Annals of the New York Academy of Sciences. 2022, Jan;
  1. 6.   RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation
  2. Poetz, Fabian; Corbo,Joshua; Levdansky,Yevgen; Spiegelhalter, Alexander; Lindner, Doris; Magg, Vera; Lebedeva, Svetlana; Schweiggert, Jorg; Schott, Johanna; Valkov,Eugene; Stoecklin, Georg
  3. Nature Communications. 2021, Dec 9; 12(1):
  1. 7.   WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells
  2. Datta, Arindam; Biswas, Kajal; Sommers, Joshua A.; Thompson, Haley; Awate, Sanket; Nicolae, Claudia M.; Thakar, Tanay; Moldovan, George-Lucian; Shoemaker, Robert H.; Sharan, Shyam K.; Brosh, Robert M.
  3. Nature Communications. 2021, Nov 12; 12(1):
  1. 8.   The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress
  2. Stromberg, Benjamin R.; Singh, Mayank; Torres, Adrian E.; Burrows, Amy C.; Pal, Debjani; Insinna, Christine; Rhee, Yosup; Dickson, Andrew S.; Westlake,Christopher; Summers, Matthew K.
  3. The Journal of Biological Chemistry. 2021, Oct; 297(4):
  1. 9.   Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome
  2. Chen,Xiang; Dorris, Zachary; Shi,Dan; Huang, Rick K; Khant,Htet; Fox,Tara; De Val Alda,Natalia; Williams, Dewight; Zhang,Ping; Walters,Kylie
  3. Structure (London, England : 1993). 2020, NOV 3; 28(11): 1206-+.
  1. 10.   Noncoding Y RNAs regulate the levels, subcellular distribution and protein interactions of their Ro60 autoantigen partner
  2. Leng,Yuanyuan; Sim,Soyeong; Magidson,Valentin; Wolin,Sandra
  3. Nucleic acids research. 2020, JUL 9; 48(12): 6919-6930.
  1. 11.   AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2
  2. Yang,Acong; Shao, Tie-Juan; Bofill De Ros,Xavier; Lian, Chuanjiang; Villanueva, Patricia; Dai,Lisheng; Gu,Shuo
  3. Nature communications. 2020, Jun 02; 11(1): 2765.
  1. 12.   Vav1 is Essential for HIF-1a Activation via a Lysosomal VEGFR1-Mediated Degradation Mechanism in Endothelial Cells
  2. Hong,Jaewoo; Min,Yongfen; Wuest, Todd; Lin,Charles
  3. Cancers. 2020, JUN; 12(6): E1374.
  1. 13.   Structural Insights into APOBEC3-Mediated Lentiviral Restriction
  2. Delviks-Frankenberry, Krista A.; Desimmie, Belete A.; Pathak,Vinay
  3. Viruses. 2020, JUN; 12(6):
  1. 14.   Chemical Modulation of Pre-mRNA Splicing in Mammalian Systems
  2. Boer, Robert E.; Torrey, Zachary R.; Schneekloth,Jay
  3. ACS CHEMICAL BIOLOGY. 2020, Apr 17; 15(4): 808-818.
  1. 15.   A protein quality control pathway at the mitochondrial outer membrane
  2. Metzger,Meredith; Scales, Jessica L; Dunklebarger, Mitchell F; Loncarek,Jadranka; Weissman,Allan
  3. eLife. 2020, Mar 02; 9
  1. 16.   Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7
  2. Hann, Zachary S; Metzger,Meredith; Weissman,Allan; Lima, Christopher D
  3. Acta crystallographica. Section F, Structural biology communications. 2019, Aug 01; 75(Pt 8): 552-560.
  1. 17.   Ro60 and Y RNAs: structure, functions, and roles in autoimmunity
  2. Boccitto,Marco; Wolin,Sandra
  3. Critical reviews in biochemistry and molecular biology. 2019, Apr; 54(2): 133-152.
  1. 18.   Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90
  2. Sager, Rebecca A.; Woodford, Mark R.; Backe, Sarah J.; Makedon, Alan M.; Baker-Williams, Alexander J.; DiGregorio, Bryanna T.; Loiselle, David R.; Haystead, Timothy A.; Zachara, Natasha E.; Prodromou, Chrisostomos; Bourboulia, Dimitra; Schmidt,Laura; Linehan, W. Marston; Bratslavsky, Gennady; Mollapour, Mehdi
  3. Cell reports. 2019, Jan 29; 26(5): 1344-1356.e5.
  1. 19.   Structure and function of Rnt1p: An alternative to RNAi for targeted RNA degradation
  2. Abou Elela, Sherif; Ji,Xinhua
  3. Wiley interdisciplinary reviews. RNA. 2019, May-Jun; 10(3):
  1. 20.   Safety and efficacy of an oncolytic viral strategy using bortezomib with ICE/R in relapsed/refractory HIV-positive lymphomas
  2. Reid, Erin G.; Looney, David; Maldarelli, Frank; Noy, Ariela; Henry, David; Aboulafia, David; Ramos, Juan Carlos; Sparano, Joseph; Ambinder, Richard F.; Lee, Jeannette; Cesarman, Ethel; Yahyaei, Sara; Mitsuyasu, Ronald; Wachsman, William
  3. Blood advances. 2018, Dec 26; 2(24): 3618-3626.
  1. 21.   Control of nuclear ß-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function
  2. Vélez-Aguilera, Griselda; de Dios Gómez-López, Juan; Jiménez-Gutiérrez, Guadalupe E; Vasquez Limeta, Alejandra; Laredo-Cisneros, Marco S; Gómez, Pablo; Winder, Steve J; Cisneros, Bulmaro
  3. Biochimica et Biophysica Acta. 2018, Feb; 1865(2): 406-420.
  1. 22.   Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFß that is critical for Vif function.
  2. Desimmie, Belete; Smith, Jessica; Matsuo, Hiroshi; Hu, Wei-Shau; Pathak, Vinay
  3. Retrovirology. 2017, Mar 17; 14(1): 19.
  1. 23.   Cullin neddylation may allosterically tune polyubiquitin chain length and topology
  2. Onel, Melis; Sumbul, Fidan; Liu, Jin; Nussinov, Ruth; Haliloglu, Turkan
  3. BIOCHEMICAL JOURNAL. 2017, Feb 20; 474(5): 781-795.
  1. 24.   Characterization of Recombinant Human IL-15 Deamidation and Its Practical Elimination through Substitution of Asparagine 77
  2. Nellis, D. F.; Michiel, D. F.; Jiang, M. S.; Esposito, D.; Davis, R.; Jiang, H. G.; Korrell, A.; Knapp, G. C.; Lucernoni, L. E.; Nelson, R. E.; Pritt, E. M.; Procter, L. V.; Rogers, M.; Sumpter, T. L.; Vyas, V. V.; Waybright, T. J.; Yang, X. Y.; Zheng, A. M.; Yovandich, J. L.; Gilly, J. A.; Mitra, G.; Zhu, J. W.
  3. Pharmaceutical Research. 2012, Mar; 29(3): 722-738.
  1. 25.   HECT and RING finger families of E3 ubiquitin ligases at a glance
  2. Metzger, M. B.; Hristova, V. A.; Weissman, A. M.
  3. Journal of Cell Science. 2012, Feb; 125(3): 531-537.
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