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  1. 1.   Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered through Cleavable and Non-Cleavable Linkers
  2. Ford, Jacob W; VanNatta, Jennifer M; Mondal, Deboprosad; Lin, Chen-Ming; Deng, Yuling; Bai, Ruoli; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G
  3. Tetrahedron. 2025, Feb 01; 171
  1. 2.   Design, Synthesis and Biological Evaluation of 2-Phenyl Indole Analogues of OXi8006 as Colchicine Site Inhibitors of Tubulin Polymerization and Vascular Disrupting Agents
  2. Vairin, Rebecca; Tamminga, Caleb; Shi, Zhe; Borchardt, Christian; Jambulapati, Jayaram; Bai, Ruoli; Wanniarachchi, Hashini; Bueno, Lorena; Hamel,Ernest; Mason, Ralph P; Trawick, Mary Lynn; Pinney, Kevin G
  3. Bioorganic & Medicinal Chemistry. 2024, Nov 07; 118: 117981.
  1. 3.   Synthesis and biological evaluation of structurally diverse 6-aryl-3-aroyl-indole analogues as inhibitors of tubulin polymerization
  2. Ren, Wen; Deng, Yuling; Ward, Jacob D; Vairin, Rebecca; Bai,Ruoli; Wanniarachchi, Hashini I; Hamal, Khagendra B; Tankoano, Pouguiniseli E; Tamminga, Caleb S; Bueno, Lorena M A; Hamel,Ernest; Mason, Ralph P; Trawick, Mary Lynn; Pinney, Kevin G
  3. European Journal of Medicinal Chemistry. 2023, Sep 06; 263: 115794.
  1. 4.   In utero exposure to diethylstilbestrol and blood DNA methylation in adult women: Results from a meta-analysis of two cohort studies
  2. Bodelon, Clara; Gierach, Gretchen L; Hatch, Elizabeth E; Riseberg, Emily; Hutchinson,Amy; Yeager,Meredith; Sandler, Dale P; Taylor, Jack A; Hoover, Robert N; Xu, Zongli; Titus, Linda; Palmer, Julie R; Troisi, Rebecca
  3. Environmental Research. 2023, Aug 15; 231(Pt. 1): 115990.
  1. 5.   Early assessment of the first wave of the COVID-19 pandemic on cancer screening services: The International Cancer Screening Network COVID-19 survey
  2. Puricelli Perin,Douglas; Elfström, K Miriam; Bulliard, Jean-Luc; Burón, Andrea; Campbell, Christine; Flugelman, Anath A; Giordano, Livia; Kamineni, Aruna; Ponti, Antonio; Rabeneck, Linda; Saraiya, Mona; Smith, Robert A; Broeders, Mireille J M
  3. Preventive medicine. 2021, Oct; 151: 106642.
  1. 6.   Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
  2. Lu, Tsan-Wen; Aoto, Phillip C.; Weng, Jui-Hung; Nielsen, Cole; Cash, Jennifer N.; Hall, James; Zhang,Ping; Simon, Sanford M.; Cianfrocco, Michael A.; Taylor, Susan S.
  3. PLOS BIOLOGY. 2020, Dec; 18(12):
  1. 7.   KSHV RNA-binding protein ORF57 inhibits P-body formation to promote viral multiplication by interaction with Ago2 and GW182
  2. Sharma, Nishi R; Majerciak,Vladimir; Kruhlak, Michael J; Yu,Lulu; Kang, Jeong Gu; Yang,Acong; Gu,Shuo; Fritzler, Marvin J; Zheng,Zhi-Ming
  3. Nucleic acids research. 2019, SEP 26; 47(17): 9368-9385.
  1. 8.   Triple-negative breast cancer cell line sensitivity to englerin A identifies a new, targetable subtype
  2. Grant, Corena V; Carver, Chase M; Hastings, Shayne D; Ramachandran, Karthik; Muniswamy, Madesh; Risinger, April L; Beutler,John; Mooberry, Susan L
  3. Breast cancer research and treatment. 2019, SEP; 177(2): 345-355.
  1. 9.   T-Cell Deletion of MyD88 Connects IL17 and I kappa B zeta to RAS Oncogenesis
  2. Cataisson, Christophe; Salcedo, Rosalba; Michalowski, Aleksandra M.; Klosterman, Mary; Naik, Shruti; Li, Luowei; Pan, Michelle J.; Sweet, Amalia; Chen, Jin-Qiu; Kostecka, Laurie G.; Karwan,Megan; Smith, Loretta; Dai,Ren; Stewart, C. Andrew; Lyakh, Lyudmila; Hsieh,Wang-Ting; Khan, Asra; Yang, Howard; Lee, Maxwell; Trinchieri, Giorgio; Yuspa, Stuart H.
  3. MOLECULAR CANCER RESEARCH. 2019, AUG; 17(8): 1759-1773.
  1. 10.   Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors
  2. Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Schiaffino Ortega, Santiago; Chayah, Mariem; Kimatrai Salvador, Maria; Carlota Lopez-Cara, Luisa; Brancale, Andrea; Ferla, Salvatore; Hamel,Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Mattiuzzo, Elena; Viola, Giampietro
  3. JOURNAL OF MEDICINAL CHEMISTRY. 2019, Feb 14; 62(3): 1274-1290.
  1. 11.   Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes
  2. Hall, Michael; Murray, Caroline A.; Valdez, Michael J.; Perantoni, Alan
  3. PLOS GENETICS. 2017, Feb 6; 13(2): e1006610.
  1. 12.   Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents
  2. Devkota, L.; Lin, C. M.; Strecker, T. E.; Wang, Y.; Tidmore, J. K.; Chen, Z.; Guddneppanavar, R.; Jelinek, C. J.; Lopez, R.; Liu, L.; Hamel, E.; Mason, R. P.; Chaplin, D. J.; Trawick, M. L.; Pinney, K. G.
  3. Bioorganic & Medicinal Chemistry. 2016, 1-Mar; 24(5): 938-56.
  1. 13.   Antineoplastic Agents. 548. Synthesis of lodo- and Diiodocombstatin Phosphate Prodrugs
  2. Pettit, G. R.; Rosenberg, H. J.; Dixon, R.; Knight, J. C.; Hamel, E.; Chapuis, J. C.; Pettit, R. K.; Hogan, F.; Sumner, B.; Ain, K. B.; Trickey-Platt, B.
  3. Journal of Natural Products. 2012, Mar; 75(3): 385-393.
  1. 14.   Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells
  2. He, S.; Wang, J. N.; Kato, K.; Xie, F.; Varambally, S.; Mineishi, S.; Kuick, R.; Mochizuki, K.; Liu, Y. N. A.; Nieves, E.; Mani, R. S.; Chinnaiyan, A. M.; Marquez, V. E.; Zhang, Y.
  3. Blood. 2012, Feb; 119(5): 1274-1282.
  1. 15.   Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors
  2. Leese, M. P.; Jourdan, F.; Dohle, W.; Kimberley, M. R.; Thomas, M. P.; Bai, R. L.; Hamel, E.; Ferrandis, E.; Potter, B. V. L.
  3. Acs Medicinal Chemistry Letters. 2012, Jan; 3(1): 5-9.
  1. 16.   A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening
  2. Horie, K.; Kokubu, C.; Yoshida, J.; Akagi, K.; Isotani, A.; Oshitani, A.; Yusa, K.; Ikeda, R.; Huang, Y.; Bradley, A.; Takeda, J.
  3. Nature Methods. 2011, Dec; 8(12): 1071-+.
  1. 17.   Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2-(3 ',4 ',5 '-Trimethoxybenzoyl)benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis
  2. Romagnoli, R.; Baraldi, P. G.; Lopez-Cara, C.; Cruz-Lopez, O.; Carrion, M. D.; Salvador, M. K.; Bermejo, J.; Estevez, S.; Estevez, F.; Balzarini, J.; Brancale, A.; Ricci, A.; Chen, L. C.; Kim, J. G.; Hamel, E.
  3. Chemmedchem. 2011, Oct; 6(10): 1841-1853.
  1. 18.   Synthetic and Application Perspectives of Azapodophyllotoxins: Alternative Scaffolds of Podophyllotoxin
  2. Kumar, A.; Kumar, V.; Alegria, A. E.; Malhotra, S. V.
  3. Current Medicinal Chemistry. 2011, Sep; 18(25): 3853-3870.
  1. 19.   Regioselective Synthesis of Water-Soluble Monophosphate Derivatives of Combretastatin A-1
  2. Tanpure, R. P.; Nguyen, B. L.; Strecker, T. E.; Aguirre, S.; Sharma, S.; Chaplin, D. J.; Siim, B. G.; Hamel, E.; Lippert, J. W.; Pettit, G. R.; Trawick, M. L.; Pinney, K. G.
  3. Journal of Natural Products. 2011, Jul; 74(7): 1568-1574.
  1. 20.   Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets
  2. Sandovici, I.; Smith, N. H.; Nitert, M. D.; Ackers-Johnson, M.; Uribe-Lewis, S.; Ito, Y.; Jones, R. H.; Marquez, V. E.; Cairns, W.; Tadayyon, M.; O'Neill, L. P.; Murrell, A.; Ling, C.; Constancia, M.; Ozanne, S. E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2011, Mar; 108(13): 5449-5454.
  1. 21.   Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
  2. Vaegter, C. B.; Jansen, P.; Fjorback, A. W.; Glerup, S.; Skeldal, S.; Kjolby, M.; Richner, M.; Erdmann, B.; Nyengaard, J. R.; Tessarollo, L.; Lewin, G. R.; Willnow, T. E.; Chao, M. V.; Nykjaer, A.
  3. Nature Neuroscience. 2011, Jan; 14(1): 54-U78.
  1. 22.   Induction of Metastatic Gastric Cancer by Peroxisome Proliferator-Activated Receptor delta Activation
  2. Pollock, C. B.; Rodriguez, O.; Martin, P. L.; Albanese, C.; Li, X.; Kopelovich, L.; Glazer, R. I.
  3. Ppar Research. 2010, Dec 27; 12.
  1. 23.   STAT1 activation regulates proliferation and differentiation of renal progenitors
  2. Wang, H.; Yang, Y.; Sharma, N.; Tarasova, N. I.; Timofeeva, O. A.; Winkler-Pickett, R. T.; Tanigawa, S.; Perantoni, A. O.
  3. Cellular Signalling. 2010, Nov; 22(11): 1717-1726.
  1. 24.   Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G(1)/S transition
  2. Li, W.; Kotoshiba, S.; Berthet, C.; Hilton, M. B.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(2): 486-491.
  1. 25.   K3 Fragment of Amyloidogenic beta(2)-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis
  2. Mustata, M.; Capone, R.; Jang, H.; Arce, F. T.; Ramachandran, S.; Lal, R.; Nussinov, R.
  3. Journal of the American Chemical Society. 2009 131(41): 14938-14945.
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