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  1. 1.   Optimized mammalian expression system for the ubiquitin E3 ligase E6AP/UBE3A
  2. Schafer,Annie; Muli,Christine; Heikal,Rehab; Dyba,Marzena; Tarasov,Sergey; Stratton, Margaret M; Strieter, Eric R; Walters,Kylie
  3. Protein Expression and Purification. 2025, Jan 09; 106661.
  1. 2.   HIF1a Plays a Crucial Role in the Development of TFE3-Rearranged Renal Cell Carcinoma by Orchestrating a Metabolic Shift Toward Fatty Acid Synthesis
  2. Nishizawa, Hidekazu; Funasaki, Shintaro; Ma, Wenjuan; Kubota, Yoshiaki; Watanabe, Kazuhide; Arima, Yuichiro; Kuroda, Shoichiro; Ito, Takaaki; Furuya, Mitsuko; Motoshima, Takanobu; Nishiyama, Akira; Mehanna, Sally; Satou, Yorifumi; Hasumi, Hisashi; Jikuya, Ryosuke; Makiyama, Kazuhide; Tamura, Tomohiko; Oike, Yuichi; Tanaka, Yasuhito; Suda, Toshio; Schmidt,Laura; Linehan, W Marston; Baba, Masaya; Kamba, Tomomi
  3. Genes to Cells : devoted to molecular & cellular mechanisms. 2025, Jan; 30(1): e13195.
  1. 3.   High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma
  2. Lang, Martin; Schmidt,Laura; Wilson, Kelli M; Ricketts, Christopher J; Sourbier, Carole; Vocke, Cathy D; Wei, Darmood; Crooks, Daniel R; Yang, Youfeng; Gibbs, Benjamin K; Zhang, Xiaohu; Klumpp-Thomas, Carleen; Chen, Lu; Guha, Rajarshi; Ferrer, Marc; McKnight, Crystal; Itkin, Zina; Wangsa, Darawalee; Wangsa, Danny; James,Amy; Difilippantonio,Simone; Karim, Baktir; Morís, Francisco; Ried, Thomas; Merino, Maria J; Srinivasan, Ramaprasad; Thomas, Craig J; Linehan, W Marston
  3. Journal of Experimental & Clinical Cancer Research : CR. 2023, Apr 25; 42(1): 99.
  1. 4.   TFEB and TFE3 drive kidney cystogenesis and tumorigenesis
  2. Di Malta, Chiara; Zampelli, Angela; Granieri, Letizia; Vilardo, Claudia; De Cegli, Rossella; Cinque, Laura; Nusco, Edoardo; Pece, Salvatore; Tosoni, Daniela; Sanguedolce, Francesca; Sorrentino, Nicolina Cristina; Merino, Maria J; Nielsen, Deborah; Srinivasan, Ramaprasad; Ball, Mark W; Ricketts, Christopher J; Vocke, Cathy D; Lang, Martin; Karim,Baktiar; Lanfrancone, Luisa; Schmidt,Laura; Linehan, W Marston; Ballabio, Andrea
  3. EMBO Molecular Medicine. 2023, Mar 29; e16877.
  1. 5.   E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure
  2. Buel,Gwen; Chen,Xiang; Myint,Wazo; Kayode, Olumide; Folimonova,Varvara; Cruz, Anthony; Skorupka,Kate; Matsuo,Hiroshi; Walters,Kylie
  3. Structure (London, England : 1993). 2023, Feb 14; 31(4): 395-410.
  1. 6.   Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate
  2. Funasaki, Shintaro; Mehanna, Sally; Ma, Wenjuan; Nishizawa, Hidekazu; Kamikubo, Yasuhiko; Sugiyama, Hiroshi; Ikeda, Shuji; Motoshima, Takanobu; Hasumi, Hisashi; Linehan, W Marston; Schmidt,Laura; Ricketts, Chris; Suda, Toshio; Oike, Yuichi; Kamba, Tomomi; Baba, Masaya
  3. Cancer Science. 2022, Apr 09;
  1. 7.   The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress
  2. Stromberg, Benjamin R.; Singh, Mayank; Torres, Adrian E.; Burrows, Amy C.; Pal, Debjani; Insinna, Christine; Rhee, Yosup; Dickson, Andrew S.; Westlake,Christopher; Summers, Matthew K.
  3. The Journal of Biological Chemistry. 2021, Oct; 297(4):
  1. 8.   In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors
  2. Wilson,Brice; Voeller, Donna; Smith,Emily; Wamiru,Antony; Goncharova,Katya; Liu, Gang; Lipkowitz, Stanley; O'Keefe,Barry
  3. SLAS DISCOVERY. 2021, Aug 21; 26(7, SI): 870-884.
  1. 9.   Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
  2. Lun, Cheng Man; Waheed,Abdul; Majadly, Alhlam; Powell, Nicole; Freed, Eric O.
  3. mBio. 2021, Mar 16; 12(2):
  1. 10.   CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity
  2. Shrestha, Roshan L.; Rossi, Austin; Wangsa, Darawalee; Hogan, Ann K.; Zaldana, Kimberly S.; Suva, Evelyn; Chung, Yang Jo; Sanders,Chelsea; Difilippantonio,Simone; Karpova, Tatiana S.; Karim,Baktiar; Foltz, Daniel R.; Fachinetti, Daniele; Aplan, Peter D.; Ried, Thomas; Basrai, Munira A.
  3. The Journal of Cell Biology. 2021, Feb 23; 220(4):
  1. 11.   Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation
  2. Aiderus, Aziz; Contreras-Sandoval, Ana M; Meshey, Amanda L; Newberg, Justin Y; Ward, Jerrold M; Swing,Debbie; Copeland, Neal G; Jenkins, Nancy A; Mann, Karen M; Mann, Michael B
  3. Cancers. 2021, Jan 09; 13(2):
  1. 12.   The Role of Conformational Dynamics in the Recognition and Regulation of Ubiquitination
  2. Khago, Domarin; Fucci,Ian; Byrd,Robert
  3. Molecules (Basel, Switzerland). 2020, Dec 15; 25(24):
  1. 13.   Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome
  2. Chen,Xiang; Dorris, Zachary; Shi,Dan; Huang, Rick K; Khant,Htet; Fox,Tara; De Val Alda,Natalia; Williams, Dewight; Zhang,Ping; Walters,Kylie
  3. Structure (London, England : 1993). 2020, NOV 3; 28(11): 1206-+.
  1. 14.   A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii
  2. Mandalasi, Msano; Kim, Hyun W.; Thieker, David; Sheikh, M. Osman; Gas-Pascual, Elisabet; Rahman,Kazi; Zhao, Peng; Daniel, Nitin G.; van der Wel, Hanke; Ichikawa, H. Travis; Glushka, John N.; Wells, Lance; Woods, Robert J.; Wood, Zachary A.; West, Christopher M.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, JUL 3; 295(27): 9223-9243.
  1. 15.   Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
  2. Magnussen, Helge M.; Ahmed, Syed F.; Sibbet, Gary J.; Hristova, Ventzislava A.; Nomura, Koji; Hock, Andreas K.; Archibald, Lewis J.; Jamieson, Andrew G.; Fushman, David; Vousden, Karen H.; Weissman, Allan M.; Huang, Danny T.
  3. Nature communications. 2020, Apr 29; 11(1):
  1. 16.   Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond
  2. Zhao, Bo; Tsai,Yien Che; Jin, Bo; Wang, Bufan; Wang, Yiyang; Zhou, Han; Carpenter, Tomaya; Weissman,Allan; Yin, Jun
  3. Pharmacological reviews. 2020, Apr; 72(2): 380-413.
  1. 17.   A protein quality control pathway at the mitochondrial outer membrane
  2. Metzger,Meredith; Scales, Jessica L; Dunklebarger, Mitchell F; Loncarek,Jadranka; Weissman,Allan
  3. eLife. 2020, Mar 02; 9
  1. 18.   FLCN alteration drives metabolic reprogramming towards nucleotide synthesis and cyst formation in salivary gland
  2. Isono, Yasuhiro; Furuya, Mitsuko; Kuwahara, Tatsu; Sano, Daisuke; Suzuki, Kae; Jikuya, Ryosuke; Mitome, Taku; Otake, Shinji; Kawahara, Takashi; Ito, Yusuke; Muraoka, Kentaro; Nakaigawa, Noboru; Kimura, Yayoi; Baba, Masaya; Nagahama, Kiyotaka; Takahata, Hiroyuki; Saito, Ichiro; Schmidt,Laura; Linehan, W Marston; Kodama, Tatsuhiko; Yao, Masahiro; Oridate, Nobuhiko; Hasumi, Hisashi
  3. Biochemical and biophysical research communications. 2020, FEB 19; 522(4): 931-938.
  1. 19.   Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease
  2. Mao, Liming; Kitani, Atsushi; Similuk, Morgan; Oler, Andrew J.; Albenberg, Lindsey; Kelsen, Judith; Aktay, Atiye; Quezado, Martha; Yao, Michael; Montgomery-Recht, Kim; Fuss, Ivan J.; Strober, Warren
  3. Journal of Clinical Investigation. 2018, May 01; 128(5): 1793-1806.
  1. 20.   Characterization of a cytoplasmic glucosyltransferase that extends the core trisaccharide of the Toxoplasma Skp1 E3 ubiquitin ligase subunit
  2. Rahman, Kazi; Mandalasi, Msano; Zhao, Peng; Sheikh, M. Osman; Taujale, Rahil; Kim, Hyun W.; van der Wel, Hanke; Matta, Khushi; Kannan, Natarajan; Glushka, John N.; Wells, Lance; West, Christopher M.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2017, NOV 10; 292(45): 18644-18659.
  1. 21.   The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation
  2. von Eyss, B.; Maaskola, J.; Memczak, S.; Mollmann, K.; Schuetz, A.; Loddenkemper, C.; Tanh, M. D.; Otto, A.; Muegge, K.; Heinemann, U.; Rajewsky, N.; Ziebold, U.
  3. Embo Journal. 2012, Feb; 31(4): 972-985.
  1. 22.   The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation
  2. Weissman, A. M.; Shabek, N.; Ciechanover, A.
  3. Nature Reviews Molecular Cell Biology. 2011, Sep; 12(9): 605-620.
  1. 23.   Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People
  2. McKay, G. J.; Silvestri, G.; Chakravarthy, U.; Dasari, S.; Fritsche, L. G.; Weber, B. H.; Keilhauer, C. N.; Klein, M. L.; Francis, P. J.; Klaver, C. C.; Vingerling, J. R.; Ho, L.; De Jong, P.; Dean, M.; Sawitzke, J.; Baird, P. N.; Guymer, R. H.; Stambolian, D.; Orlin, A.; Seddon, J. M.; Peter, I.; Wright, A. F.; Hayward, C.; Lotery, A. J.; Ennis, S.; Gorin, M. B.; Weeks, D. E.; Kuo, C. L.; Hingorani, A. D.; Sofat, R.; Cipriani, V.; Swaroop, A.; Othman, M.; Kanda, A.; Chen, W.; Abecasis, G. R.; Yates, J. R.; Webster, A. R.; Moore, A. T.; Seland, J. H.; Rahu, M.; Soubrane, G.; Tomazzoli, L.; Topouzis, F.; Vioque, J.; Young, I. S.; Fletcher, A. E.; Patterson, C. C.
  3. American Journal of Epidemiology. 2011, Jun; 173(12): 1357-1364.
  1. 24.   Overexpression of enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy
  2. Sasaki, D.; Imaizumi, Y.; Hasegawa, H.; Osaka, A.; Tsukasaki, K.; Choi, Y. L.; Mano, H.; Marquez, V. E.; Hayashi, T.; Yanagihara, K.; Moriwaki, Y.; Miyazaki, Y.; Kamihira, S.; Yamada, Y.
  3. Haematologica-the Hematology Journal. 2011, May; 96(5): 712-719.
  1. 25.   Alternative Allosteric Mechanisms Can Regulate the Substrate and E2 in SUMO Conjugation
  2. Karaca, E.; Tozluoglu, M.; Nussinov, R.; Haliloglu, T.
  3. Journal of Molecular Biology. 2011, Mar; 406(4): 620-630.
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