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  1. 1.   Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
  2. Magnussen, Helge M.; Ahmed, Syed F.; Sibbet, Gary J.; Hristova, Ventzislava A.; Nomura, Koji; Hock, Andreas K.; Archibald, Lewis J.; Jamieson, Andrew G.; Fushman, David; Vousden, Karen H.; Weissman, Allan M.; Huang, Danny T.
  3. Nature communications. 2020, Apr 29; 11(1):
  1. 2.   BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation
  2. Zong, Dali; Adam, Salome; Wang, Yifan; Sasanuma, Hiroyuki; Callen, Elsa; Murga, Matilde; Day, Amanda; Kruhlak, Michael J.; Wong, Nancy; Munro, Meagan; Chaudhuri, Arnab Ray; Karim,Baktiar; Xia, Bing; Takeda, Shunichi; Johnson, Neil; Durocher, Daniel; Nussenzweig, Andre
  3. Molecular cell. 2019, MAR 21; 73(6): 1267-+.
  1. 3.   Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration
  2. Diril, M. K.; Ratnacaram, C. K.; Padmakumar, V. C.; Du, T. H.; Wasser, M.; Coppola, V.; Tessarollo, L.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2012, Mar; 109(10): 3826-3831.
  1. 4.   Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G(1)/S transition
  2. Li, W.; Kotoshiba, S.; Berthet, C.; Hilton, M. B.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(2): 486-491.
  1. 5.   Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
  2. Satyanarayana, A.; Kaldis, P.
  3. Oncogene. 2009 28(33): 2925-2939.
  1. 6.   Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53
  2. Clement, J. A.; Kitagaki, J.; Yang, Y.; Saucedo, C. J.; O'Keefe, B. R.; Weissman, A. M.; Mckee, T. C.; McMahon, J. B.
  3. Bioorganic & Medicinal Chemistry. 2008 16(23): 10022-10028.
  1. 7.   Targeting tumor cells expressing p53 with a water-soluble inhibitor of Hdm2
  2. Kitagaki, J.; Agama, K. K.; Pommier, Y.; Yang, Y. L.; Weissman, A. M.
  3. Molecular Cancer Therapeutics. 2008 7(8): 2445-2454.
  1. 8.   Vascular defects and liver damage by the acute inactivation of the VHL gene during mouse embryogenesis
  2. Hong, S. B.; Furihata, M.; Baba, M.; Zbar, B.; Schmidt, L. S.
  3. Laboratory Investigation. 2006, Jul; 86(7): 664-675.
  1. 9.   Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation
  2. Berthet, C.; Klarmann, K. D.; Hilton, M. B.; Suh, H. C.; Keller, J. R.; Kiyokawa, H.; Kaldis, P.
  3. Developmental Cell. 2006, MAY; 10(5): 563-573.
  1. 10.   Tumor suppression and normal aging in mice with constitutively high p53 activity
  2. Mendrysa, S. M.; O'Leary, K. A.; McElwee, M. K.; Michalowski, J.; Eisenman, R. N.; Powell, D. A.; Perry, M. E.
  3. Genes & Development. 2006, JAN 1; 20(1): 16-21.
  1. 11.   FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis
  2. Li, C. L.; Xu, X. L.; Nelson, D. K.; Williams, T.; Kuehn, M. R.; Deng, C. X.
  3. Development. 2005, NOV; 132(21): 4755-4764.
  1. 12.   Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele
  2. Graveel, C.; Su, Y. L.; Koeman, J.; Wang, L. M.; Tessarollo, L.; Fiscella, M.; Birchmeier, C.; Swiatek, P.; Bronson, R.; Woude, G. V.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2004, DEC 7; 101(49): 17198-17203.
  1. 13.   BRCA2 deficiency in mice leads to meiotic impairment and infertility
  2. Sharan, S. K.; Pyle, A.; Coppola, V.; Babus, J.; Swaminathan, S.; Benedict, J.; Swing, D.; Martin, B. K.; Tessarollo, L.; Evans, J. P.; Flaws, J. A.; H, el
  3. Development. 2004 131(1): 131-142.
  1. 14.   Regulating the p53 system through ubiquitination
  2. Yang, Y. L.; Li, C. C. H.; Weissman, A. M.
  3. Oncogene. 2004 23(11): 2096-2106.
  1. 15.   Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene
  2. Ma, W. B.; Tessarollo, L.; Hong, S. B.; Baba, M.; Southon, E.; Back, T. C.; Spence, S.; Lobe, C. G.; Sharma, N.; Maher, G. W.; Pack, S.; Vortmeyer, A. O.; Guo, C. F.; Zbar, B.; Schmidt, L. S.
  3. Cancer Research. 2003 63(17): 5320-5328.
  1. 16.   Aberrant splicing induced by missense mutations in BRCA1: clues from a humanized mouse model
  2. Yang, Y. P.; Swaminathan, S.; Martin, B. K.; Sharan, S. K.
  3. Human Molecular Genetics. 2003 12(17): 2121-2131.
  1. 17.   Sequence, chromosomal location and expression analysis of the murine homologue of human RAD51L2/RAD51C
  2. Leasure, C. S.; Chandler, J.; Gilbert, D. J.; Householder, D. B.; Stephens, R.; Copeland, N. G.; Jenkins, N. A.; Sharan, S. K.
  3. Gene. 2001 271(1): 59-67.
  1. 18.   Stress signals utilize multiple pathways to stabilize p53
  2. Ashcroft, M.; Taya, Y.; Vousden, K. H.
  3. Molecular and Cellular Biology. 2000 20(9): 3224-3233.
  1. 19.   Regulation and activation of p53 and its family members
  2. Lohrum, M. A. E.; Vousden, K. H.
  3. Cell Death and Differentiation. 1999 6(12): 1162-1168.
  1. 20.   Regulation of p53 stability
  2. Ashcroft, M.; Vousden, K. H.
  3. Oncogene. 1999 18(53): 7637-7643.
  1. 21.   Regulation of Cardiac Development By Receptor Tyrosine Kinases
  2. Tessarollo, L.; Hempstead, B. L.
  3. Trends in Cardiovascular Medicine. 1998 8(1): 34-40.
  1. 22.   The bHLH-Zip transcription factor Tfeb is essential for placental vascularization
  2. Steingrimsson, E.; Tessarollo, L.; Reid, S. W.; Jenkins, N. A.; Copeland, N. G.
  3. Development. 1998 125(23): 4607-4616.
  1. 23.   Regulation of Mdm2-Directed Degradation By the C Terminus of P53
  2. Kubbutat, M. H. G.; Ludwig, R. L.; Ashcroft, M.; Vousden, K. H.
  3. Molecular and Cellular Biology. 1998 18(10): 5690-5698.
  1. 24.   Regulation of P53 Stability By Mdm2
  2. Kubbutat, M. H. G.; Jones, S. N.; Vousden, K. H.
  3. Nature. 1997 387(6630): 299-303.
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